Hacettepe Journal of Biology and Chemistry最新文献_第9页

DNA/HSA Interactions and Anticancer Activity of a Palladium(II) Saccharinate Complex Bearing Ethyldiphenylphosphine 含乙基二苯基膦的钯(II)糖化配合物的DNA/HSA相互作用及抗癌活性

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-12-22 DOI: 10.15671/hjbc.836685

Ceyda Icsel

引用次数: 0

Determination of Metal Concentrations in Değirmendere Stream Drainage Area of Southeastern Black Sea Coast of Turkey 土耳其黑海东南海岸Değirmendere河流流域金属浓度测定

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-12-09 DOI: 10.15671/hjbc.686166

A. Alkan, Koray Özşeker, I. Yıldız, Cemal Dinçer

引用次数: 1

MODERN METHODS FOR WASTEWATER TREATMENT 污水处理的现代方法

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-12-09 DOI: 10.15671/hjbc.686544

E. Gadirova

引用次数: 3

Effects of Asymmetric Nanopore Geometries on Nanoparticle Sensing Using Track-Etched Nanopore Membranes 不对称纳米孔几何形状对轨迹蚀刻纳米孔膜纳米粒子传感的影响

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-11-01 DOI: 10.15671/hjbc.667462

Dürdane Yilmaz, D. Kaya, K. Kececi, A. Dinler

{"title":"Effects of Asymmetric Nanopore Geometries on Nanoparticle Sensing Using Track-Etched Nanopore Membranes","authors":"Dürdane Yilmaz, D. Kaya, K. Kececi, A. Dinler","doi":"10.15671/hjbc.667462","DOIUrl":"https://doi.org/10.15671/hjbc.667462","url":null,"abstract":"Resistive pulse sensing, based on the Coulter Counter principle, is an important assay for sensing and separation processes to detect/discriminate several types of particles in various mediums. In such a set-up, attaining the signal from the smaller particles can be hard compared to larger particles. In this work, we focus on the critical role of pore shape on signal precision. We have simulated hourglass and cigar shaped nanopores to study the sensitivity for small particles. We have considered the translocation of 120 nm diameter particle by altering the surface charge as -0.001 C/m2, -0.007 C/m2 and -0.015 C/m2 under the applied potential between -0.3 V and -1 V with 0.1 increments. We have compared the signals in different concentration for identical-sized particles with varying surface charges. Comparison of pulse magnitudes and normalized current changes obtained from each pore shapes have shown that the cigar shaped pore yields more prominent signals for smaller sized particles than the hourglass pore. The results reveal that the hourglass shaped pore provides higher sensitivity than cigar shaped to discriminate the smaller particles and the hourglass pore might be preferable for nanopore sensor applications.","PeriodicalId":12939,"journal":{"name":"Hacettepe Journal of Biology and Chemistry","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78635915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Electrochemical Synthesis of Cauliflower-Like PtPd@PVF Nanocatalyst for Electrooxidation of Methanol 菜花样PtPd@PVF纳米甲醇电氧化催化剂的电化学合成

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-10-30 DOI: 10.15671/hjbc.704959

M. S. Çelebi, Kübra Öztürk, Mehmet Dumangöz

引用次数: 0

Radiation-Grafted Polymer Electrolyte Membranes for Fuel Cells 辐射接枝聚合物电解质膜用于燃料电池

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-10-28 DOI: 10.15671/hjbc.813239

Begüm Yarar Kaplan, A. Kırlıoğlu, E. Jamil, Alp Yürüm, Naeimeh Rajabalizadeh, N. Haghmoradi, Bilal Iskandarani, Hamed Salimkhani, S. A. Gürsel

{"title":"Radiation-Grafted Polymer Electrolyte Membranes for Fuel Cells","authors":"Begüm Yarar Kaplan, A. Kırlıoğlu, E. Jamil, Alp Yürüm, Naeimeh Rajabalizadeh, N. Haghmoradi, Bilal Iskandarani, Hamed Salimkhani, S. A. Gürsel","doi":"10.15671/hjbc.813239","DOIUrl":"https://doi.org/10.15671/hjbc.813239","url":null,"abstract":"Fuel cells are one of the most efficient energy conversion systems to produce electricity. A solid ion-conducting polymer membrane is employed as both separator and electrolyte for polymer electrolyte membrane fuel cells and anion-exchange membrane fuel cells. Radiation-induced graft polymerization is a versatile method for the fabrication of low-cost alternatives to commercial polymer membranes. In this method, typically a base polymer is exposed to ionizing radiation which generates active radical sites within the polymer substrate. Then a suitable vinyl monomer is polimerized on these active sites to form a graft copolymer. Finally, a subsequent chemical treatment is performed to introduce hydrophilic groups to hydrophobic polymer backbone so that an ion conducting membrane is formed. There are various studies about the influence of radiation grafting parameters on membrane properties. Moreover, the favorable fuel cell relevant and polarization properties of such radiation-grafted membranes were reported. Thus, radiation-grafted polymer membranes are one of the significant low-cost alternatives for fuel cells. This review focuses on the preparation, characterization of fuel cell relevant properties and fuel cell performance of radiation-grafted membranes.","PeriodicalId":12939,"journal":{"name":"Hacettepe Journal of Biology and Chemistry","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86187362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The role of the Cellular Antioxidant Defense System on Oxidative Stress in Acute Appendicitis 细胞抗氧化防御系统在急性阑尾炎氧化应激中的作用

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-10-27 DOI: 10.15671/hjbc.728686

Ayetullah Temiz, M. Işık, Y. Albayrak, H. Duran, A. Aslan, Yeliz Demir, Ayşe Albayrak, Ş. Beydemir

引用次数: 0

Synthesis of Polymer Brushes by Surface-Initiated Controlled/Living Free Radical Polymerization Techniques 表面引发控制/活性自由基聚合技术合成聚合物刷

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-10-21 DOI: 10.15671/hjbc.813565

Kübra Hüküm Özkan, Esma Mutlutürk, Tugba D Caliskan, T. Caykara

{"title":"Synthesis of Polymer Brushes by Surface-Initiated Controlled/Living Free Radical Polymerization Techniques","authors":"Kübra Hüküm Özkan, Esma Mutlutürk, Tugba D Caliskan, T. Caykara","doi":"10.15671/hjbc.813565","DOIUrl":"https://doi.org/10.15671/hjbc.813565","url":null,"abstract":"The surface modifications are necessary to alter the inherent surface physical/chemical properties of materials in terms of adhesion, wettability, friction, biocompatibility etc. for using in textile, electronic and biomedical industries. Surface modifications are usually made by grafting of polymer brushes to the solid substrates. The grafting process allows controlling and manipulation of surface properties without changing the chemical structure of polymers. Besides their chemical structures, grafting density of polymer brushes and average distance between the polymer chains attached to the surface are also important parameters, affecting the intended use of the grafted materials. Synthesis of functional polymer brushes is generally carried out by one of surface-initiated controlled/living free radical polymerization techniques, namely Atom Transfer Radical Polymerization (ATRP), Nitroxide-Mediated Polymerization (NMP), Photoiniferter-Mediated Polymerization (PIMP) and Reversible Addition-Fragmentation Chain Transfer Polymerization (RAFT). This review reports the strategies of these techniques for generating polymer brushes and summarizes the application of polymer brushes in multiple fields.","PeriodicalId":12939,"journal":{"name":"Hacettepe Journal of Biology and Chemistry","volume":"58 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90681522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Molecular Imprinting Technology for Biomimetic Assemblies 仿生装配的分子印迹技术

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-10-16 DOI: 10.15671/hjbc.801427

Nilay Bereli, Semra Akgönüllü, Sevgi Aslıyüce, Duygu Çimen, Ilgım Göktürk, Deniz Türkmen, H. Yavuz, A. Denizli

{"title":"Molecular Imprinting Technology for Biomimetic Assemblies","authors":"Nilay Bereli, Semra Akgönüllü, Sevgi Aslıyüce, Duygu Çimen, Ilgım Göktürk, Deniz Türkmen, H. Yavuz, A. Denizli","doi":"10.15671/hjbc.801427","DOIUrl":"https://doi.org/10.15671/hjbc.801427","url":null,"abstract":"The term biomimetic can be simply defined as the examination of nature. The scientists inspired by the enormous diversity of nature to solve human problems or facilitate daily life by mimicking natural models, systems, and elements especially in the biomedical and therapeutic applications to make better drugs, artificial organs, sensing instruments, etc. Biological recognition elements like proteins, antibodies, enzymes, DNA, lectins, aptamers, cells, and viruses have been heavily used to ensure specificity in such applications in spite of their lack of stability and reusability. However, in the last two decades molecularly imprinted polymers, MIPs, have been synthesized as an alternative to mimic natural biological interactions for a broad spectrum of templates by means of coordinating functional monomers around template in the presence of cross-linker. This review will outline the broad contours of biomimetics prepared by molecular imprinting techniques and their practical applications in the separation techniques, tissue engineering applications, biomimetic surfaces, sensors, artificial membranes, and drug delivery systems.","PeriodicalId":12939,"journal":{"name":"Hacettepe Journal of Biology and Chemistry","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79920329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Micro and Nanogels for Biomedical Applications 生物医学应用的微纳米凝胶

Hacettepe Journal of Biology and Chemistry Pub Date : 2020-10-16 DOI: 10.15671/hjbc.810599

M. Can, O. Güven, N. Sahiner

{"title":"Micro and Nanogels for Biomedical Applications","authors":"M. Can, O. Güven, N. Sahiner","doi":"10.15671/hjbc.810599","DOIUrl":"https://doi.org/10.15671/hjbc.810599","url":null,"abstract":"Micro and nano hydrogels developed from natural and synthetic polymers have garnered great deal of attention in scientific and industrial realms due to their higher surface area, degree of swelling and active material loading capacity, softness and flexibility, as well as their similarity to natural tissues. Particularly, biocompatible, non-toxic, and biodegradable micro/nano vehicles with tailor made design and functionalization facilities their use with excellent feasibility for a variety of biomedical applications such as tissue engineering, bioimaging and drug delivery. However, these platforms require rational design and functionalization strategies to cope with barriers of in vivo environment to pass into clinical use. Firstly, an ideal carrier should be biocompatible, and capable of evasion from immune elimination, specifically target at desired sites and sustainably release the therapeutic cargo in response to microenvironment conditions. Despite the few setbacks in micro/nano vehicle design and several successful formulations translated to clinical use and majority of the carries are yet to achieve complete success for all biological criteria. In this review, design, and functionalization strategies of micro and nanogels have been summarized and the recent progress in biomedical applications of microgels and nanogels have been outlined with a primary focus placed on drug and biomolecule delivery applications.","PeriodicalId":12939,"journal":{"name":"Hacettepe Journal of Biology and Chemistry","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83057765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3