Heliyon最新文献

{"title":"Comprehensive honey authentication in Bangladesh: Profiling physicochemical and bioactive compounds to distinguish floral sources and detect adulteration.","authors":"Roksana Al Nafiu Insha, Md Nahidul Islam, Joydeb Gomasta, Mohammad Nazmol Hasan, Md Ruhul Amin, Noor Shaila Sarmin, Md Mamunur Rahman","doi":"10.1016/j.heliyon.2024.e40203","DOIUrl":"10.1016/j.heliyon.2024.e40203","url":null,"abstract":"<p><p>This study aims to advance honey authentication in Bangladesh by developing a reliable, cost-effective, and user-friendly system capable of distinguishing floral sources and purity. We analyzed various physicochemical parameters and bioactive compounds in honey samples from diverse floral sources across Bangladesh during different floral seasons, including deliberately adulterated samples. Results showed clear distinctions among the tested parameters. Notably, moisture content exhibited considerable variability, with the highest levels found in kholisha (24.07%-24.99 %) and the lowest in black cumin honey (17.80%-27.46 %). Jujube honey exhibited the highest protein content at 10 % adulteration, whereas mustard honey showed the least at 20 % adulteration. Generally, adulterated honey samples showed a considerable deviation in protein content compared to known standards for pure honey, suggesting adulteration significantly impacts protein levels. Black cumin honey showed the highest electrical conductivity, followed by jujube. Antioxidant levels were highest in litchi honey, followed by ayurvedic and kholisha. Multivariate analysis revealed that two principal components explained 65 % of total variances and could separate the various clusters of honey samples. The pH values, total phenolic, total flavonoid, protein content, electrical conductivity, color intensity at 360 nm and 635 nm, and antioxidant properties of all tested honey samples showed a strong positive correlation. Overall, the manuscript strategically combines experimental findings with detailed analyses to explore the complex nature of honey composition, adulteration issues, and the significance of authenticating honey to maintain quality and ensure consumer trust in the market. This study is the first to employ a comprehensive set of physicochemical and bioactive indicators with multivariate analysis for honey authentication in Bangladesh, offering a novel and systematic approach to identifying purity and floral sources.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40203"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new knockin mouse carrying the E364X patient mutation for CDKL5 deficiency disorder: neurological, behavioral and molecular profiling.","authors":"C Quadalti, M Sannia, N E Humphreys, V A Baldassarro, A Gurgone, M Ascolani, L Zanella, L Giardino, C T Gross, S Croci, I Meloni, M Giustetto, A Renieri, L Lorenzini, L Calzà","doi":"10.1016/j.heliyon.2024.e40165","DOIUrl":"10.1016/j.heliyon.2024.e40165","url":null,"abstract":"<p><p>CDKL5 deficiency disorder (CDD) is a rare neurodevelopmental syndrome caused by mutations in the X-linked CDKL5 gene. Hundreds of pathogenic variants have been described, associated with a significant phenotypic heterogeneity observed among patients. To date, different knockout mouse models have been generated. Here we present a new knockin CDKL5 mouse model carrying a humanized, well-characterized nonsense variant (c.1090G > T; p.E364X) described in the C-terminal domain of the CDKL5 protein in a female patient with a milder phenotype. Both male and female <i>Cdkl5</i> ^E364X mice were analyzed. The novel <i>Cdkl5</i> ^E364X mouse showed altered neurological and motor neuron maturation, hyperactivity, defective coordination and impaired memory and cognition. Gene expression analysis highlighted an unexpected reduction of <i>Cdkl5</i> expression in <i>Cdkl5</i> ^E364X mice brain tissues, with a significant increase in overall neuron-specific gene expression and an area-dependent alteration of astrocyte- and oligodendrocyte-specific transcripts. Moreover, our results showed that the loss of CDKL5 protein had the most significant impact on the cerebellum and hippocampus, compared to other analyzed tissues. A targeted analysis to study synaptic plasticity in cerebellum and hippocampus showed reduced <i>Gabra1</i> and <i>Gabra5</i> expression levels in females, whereas <i>Gabra1</i> expression was increased in males, suggesting an opposite, sex-dependent regulation of the GABA receptor expression already described in humans. In conclusion, the novel Cdkl5^E364X mouse model is characterized by robust neurological and neurobehavioral alterations, associated with a molecular profile related to synaptic function indicative of a cerebellar GABAergic hypofunction, pointing to <i>Gabra1</i> and <i>Gabra5</i> as novel druggable target candidates for CDD.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40165"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in null hypothesis significance testing: Still going strong.","authors":"Frank Emmert-Streib","doi":"10.1016/j.heliyon.2024.e40133","DOIUrl":"10.1016/j.heliyon.2024.e40133","url":null,"abstract":"<p><p>Null hypothesis significance testing (NHST) is among the most prominent and widely used methods for analyzing data. At the same time, NHST has been criticized since many years because of misuses and misconceptions that can be found extensively in the scholarly literature. Furthermore, in recent years, NHST has been identified as one reason for the replication crisis because many studies place too much emphasis on statistical significance for drawing conclusions. As a response to those problems, calls for actions have been raised, among others by the American Statistical Association (ASA), to rectify these issues, for instance, by modifying or even abandoning NHST. In this paper, we study the reaction of the community on these discussions. Specifically, we conduct a scientometric analysis of bibliographic records to investigate the publication behavior about the usage of NHST. We conduct a trend analysis for the general community, for specific subject areas and for individual journals. Furthermore, we conduct a change-point analysis to investigate if there are continued movements or actual changes. As a result, we find that for the general community NHST is more popular than ever, however, for particular subject-areas and journals there is a clear heterogeneity and no uniform publication behavior is observable.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40133"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pan-cancer landscape of disulfidptosis across human tumors.","authors":"Kun Fang, Suxiao Jiang, Zhengjie Xu, Meng Luo, Changsheng Yan","doi":"10.1016/j.heliyon.2024.e40122","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40122","url":null,"abstract":"<p><strong>Objective: </strong>Disulfidptosis is a newly discovered disulfide stress-induced cell death form. Clinical significance and biological mechanisms of disulfidptosis in human cancers need to be further elucidated. Thus, this study was designed to characterize pan-cancer landscape of disulfidptosis across human tumors.</p><p><strong>Methods: </strong>Multi-omics features (transcriptomics, genomics, and DNA methylation) of disulfidptosis genes were investigated in TCGA pan-cancer cohorts. A disulfidptosis score system was defined across human tumors via ssGSEA. The activity of classical oncogenic pathways and hallmarks of cancer as well as the infiltration of immunocyte subpopulations were estimated, respectively. Drug sensitivity was inferred, and immune checkpoint blockade (ICB) response was evaluated in an independent cohort IMvigor210. ACHN, CAL-27, and NCI-H23 cells were transiently transfected with GYS1 siRNAs, and cell apoptosis and proliferation were measured through TUNEL and EdU assays, respectively.</p><p><strong>Results: </strong>Aberrant mRNA expression and DNA methylation of disulfidptosis genes as well as their genomic alterations were found in human tumors. The disulfidptosis score was utilized for quantifying the activity of disulfidptosis, which enabled to estimate patient prognosis. The disulfidptosis score presented positive correlations to angiogenesis and EMT, indicating the role of disulfidptosis in mediating tumor malignant features. Moreover, the score was negatively linked with infiltrating immune and stromal cells in the immune microenvironment. In the ICB cohort, shorter survival time was observed in patients with high disulfidptosis score, indicating the potential of disulfidptosis score in influencing clinical benefits from ICB. Additionally, tumors with low disulfidptosis score exhibited higher sensitivity to a few small molecular compounds, e.g., Sabutoclax, PRIMA-1MET, BIBR-1532, and Elephantin. Knockdown of disulfidptosis gene GYS1 effectively hindered tumor progression.</p><p><strong>Conclusion: </strong>Collectively, our findings depict a pan-cancer map of disulfidptosis to inform functional and therapeutic research.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40122"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"African sovereign risk premia and international market assets: A relook under the COVID-19 outbreak.","authors":"Godfred Amewu, Nana Kwame Akosah, Mohammed Armah","doi":"10.1016/j.heliyon.2024.e40194","DOIUrl":"10.1016/j.heliyon.2024.e40194","url":null,"abstract":"<p><p>Using the wavelet multiscale coherence technique, the paper examines the interdependences between global market assets, sovereign credit default swap (CDS) and yield-to-maturity on bond spread for African economies from January 2019 to March 2023. The empirical results primarily reveal a high level of coherence between global market assets and Africa's sovereign CDS and yield-to-maturity, although varying across countries and time-frequency domain. Notably, the high degree of coherence and the positive co-movement between sovereign CDS and global market assets are more concentrated at the medium and upper frequency bands. The observed intensity of co-movements between global market assets and sovereign CDS/yield-to-maturity (YTM) of bond spread, with global market assets broadly serving as leading variables, suggests that an increased global investor's risk aversion positively affects the yields on Africa market bonds. Among the global market assets, we identified that VIX (which is implied volatility of S&P500) has the dominant influence on Africa sovereign CDS/YTM compared to that emanating from Bitcoin and Godman Sachs Commodity Index. This is highly conceivable as VIX gauges bubbling global risks and uncertainties which considerably influences investor's risk aversion. The heterogeneous lead/lag dynamics also provide useful information to global investors, including by utilizing African markets to rebalance their portfolios for risk management purposes. The empirical findings thus provide further critical information to investors for hedging purposes, and to policymakers in formulating sovereign risk management policies oriented towards minimizing sovereign default risks.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40194"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of preslaughter handling approach and aging on carcass and meat quality attributes in goats.","authors":"Gamaleldin M Suliman, Abdullah N Al-Owaimer, Mohsen M Alobre, Ayman A Swelum, Maged A Algaradi, Hani Ba-Awadh, Awis-Qurni Sazili, Pavan Kumar, Ubedullah Kaka","doi":"10.1016/j.heliyon.2024.e40177","DOIUrl":"10.1016/j.heliyon.2024.e40177","url":null,"abstract":"<p><p>This study aimed to assess the impact of preslaughter handling method and aging on carcass and meat quality traits in goats. Twenty-seven male goats of Ardi breed were assigned into three treatment groups viz., the control (C), ear pulling (EP), and hind-leg pulling (HP). The carcasses were stored for post-mortem aging periods of 1, 7, and 14 days. On day 0 and the respective aging days, samples of the <i>Longissimus thoracic et lumborum</i> (LTL) muscles were collected and examined for various meat quality parameters. The preslaughter handling of goats significantly increase the total bacterial count, total Enterobacteriaceae count, and total Clostridium count. It also had a significant effect on the pH of LTL muscle during aging. A significantly lower values for pH were recorded in the treatment groups (EP and HP) as compared to the pH of the C group on day 1 of aging. Notably, both treatment groups were found to increase the shear force, hardness, and chewiness of the meat, ultimately compromising its quality. The proper treatment of meat animals, especially goats, is crucial for enhancing carcass and meat quality. Careful preslaughter handling practices by avoiding ear and hind-leg pulling can minimize negative impacts on the final product. Therefore, the significance of conducting this study lies in its potential to enhance animal welfare, improve meat quality, boost economic benefits for producers, and foster consumer confidence in meat products.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40177"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the effectiveness of dissuasive taxes as a policy tool for reducing tobacco and alcohol consumption in Cameroon: A welfare and microsimulation analysis.","authors":"Paul Tadzong Mouafo, Hilaire Nkengfack, Rodrigue Nobosse Tchoffo, Nelson Derrick Nguepi, Edmond Noubissi Domguia","doi":"10.1016/j.heliyon.2024.e40174","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40174","url":null,"abstract":"<p><p>Deterrent taxes are a crucial policy tool for reducing the consumption of harmful products like tobacco and alcohol. However, assessing dissuasive taxes impact different income groups is important to ensure that their burden is not disproportionately borne by low-income households. This study examines the effectiveness of deterrent taxes as an economic policy tool for reducing tobacco and alcohol consumption in Cameroon. We analyse the impact on household welfare and distributional effects using microsimulation analysis. The data come from the Cameroon Household Living Conditions Survey and the 2022 tax records. Our methodology is based on a dynamic computable general equilibrium (CGE) model enriched with an addiction model. The results indicate that deterrent taxes can significantly reduce the consumption of these harmful products but also have regressive effects on low-income households. In response, we recommend the adoption of a progressive tax structure and the establishment of targeted support programmes to mitigate the negative impact on vulnerable populations.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40174"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative phytochemical profile and biological activity of three <i>Terminalia</i> species as alternative antimicrobial therapies.","authors":"Jotham Yhi-Pênê N'do, Dramane Paré, Loyapin Bondé, Adama Hilou","doi":"10.1016/j.heliyon.2024.e40159","DOIUrl":"10.1016/j.heliyon.2024.e40159","url":null,"abstract":"<p><strong>Ethnopharmacological relevance: </strong>Medicinal plants can help combat antibiotic resistance by providing novel, active molecules. Three plant species of the <i>Terminalia</i> genus are widely used in traditional medicine in the Mouhoun region for the treatment of cutaneous and respiratory diseases. Therefore, it is important to determine the ethnopharmacological potential of bark extracts from the trunks of these three <i>Terminalia</i> species.</p><p><strong>Aim of the study: </strong>This study compared the phytochemical and biological activities of extracts from three <i>Terminalia</i> species to determine their ethnopharmacology.</p><p><strong>Materials and methods: </strong>The medicinal properties of the extracts were assessed based on their ability to inhibit the growth of the following microorganisms: <i>Staphylococcus aureus, Escherichia coli</i>, <i>Klebsiella pneumoniae</i>, <i>Pseudomonas aerugino</i>sa, <i>Candida albicans</i>, <i>Candida krusei</i>, <i>Candida glabrata,</i> and <i>Candida tropicalis</i>. The significant interest in these medicinal plants among the local communities were elucidated by their antioxidant properties and phytochemical composition, along with the detection key bioactive compounds. Major phytochemical groups and phenolic compounds were determined using high-performance liquid chromatography with a diode array detector. These phytochemical findings were validated by evaluating the antioxidant capacity of the extracts using DPPH, FRAP, and ABTS assays.</p><p><strong>Results: </strong>Hydroethanolic, ethanolic, and hexane extracts from the bark of three <i>Terminalia</i> species inhibited the growth of both bacteria and fungi, as evidenced by their minimum inhibitory concentrations (MICs).The findings showed that <i>Terminalia</i> species were most effective against various tested bacteria and fungi, with MICs ranging from 0.1 to 6.25 mg/mL. <i>Terminalia avicennioides</i>, <i>Terminalia macroptera,</i> and <i>Terminalia laxiflora</i> extracts demonstrated 50 % inhibition of DPPH at concentrations ranging from 0.04 to 0.6 mg/mL. Phytochemical analysis revealed the presence of several families of chemical compounds, such as total phenolics and flavonoids. Phenolic compounds identified by HPLC in ethanolic extracts of <i>T. avicennioides</i>, such as isorhamnetin, quercetin, and ferulic acid, are recognised for their antimicrobial and antioxidant properties.</p><p><strong>Conclusion: </strong>These findings establish an ethnobotany for these three <i>Terminalia</i> species, with their chromatographic characteristics facilitating the identification of key molecules of interest. The ethanolic extract of <i>T. avicennioides</i> can be used in phytomedicinal formulations against bacterial (<i>P. aeruginosa</i> and <i>S. aureus</i>) and fungal (<i>C. albicans</i> and <i>C. glabrata</i>) infections, both of which are recurrently recorded in certain skin and respiratory tract diseases.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40159"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association analyses of nutritional markers with Parkinson's disease and Alzheimer's disease.","authors":"Dong-Juan Xu, Yi-Lei Shen, Meng-Meng Hu, Ling-Ling Li, Yuan Fang, Ju-Ping He, Lu-Lu Ma, Shan-Shan Xu, Jian-Yong Wang","doi":"10.1016/j.heliyon.2024.e40191","DOIUrl":"10.1016/j.heliyon.2024.e40191","url":null,"abstract":"<p><strong>Introduction: </strong>Parkinson's disease (PD) and Alzheimer's disease (AD) are common neurodegenerative diseases with multifaceted etiology. Nutritional and metabolic abnormalities are frequently implicated in PD and AD. In this observational study, we analyzed a series of nutritional markers, and aimed to understand their association with AD and PD risk.</p><p><strong>Methods: </strong>A total of 424 PD patients, 314 AD patients, and 388 healthy controls were included. Nutritional markers including Hemoglobin A1c, vitamin B12, folate, apolipoprotein B (ApoB), apolipoprotein A1 (ApoA1), low-density lipoprotein (LDL), high-density lipoprotein, triglyceride, total cholesterol (TC), uric acid and homocysteine (HCY) were measured. Significance for odds ratios examining was <i>P</i> < 0.0045 after bonferroni correction.</p><p><strong>Results: </strong>Multifactor risk analysis showed that ApoB, LDL, and TC reduce PD risk, while HCY increase PD risk. ApoA1 and HCY are protective and risk factors for AD, respectively.</p><p><strong>Conclusion: </strong>The cross-sectional study demonstrates that HCY and lipid metabolism markers are associated with PD and AD risks. Our findings support the involvement of one-carbon metabolism and lipid metabolism disturbance in PD and AD.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40191"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of stacking sequence on the mechanical properties of banana-glass fiber hybrid laminates for automotive shells.","authors":"Mohammad Kamruzzaman, Samiul Alam","doi":"10.1016/j.heliyon.2024.e40130","DOIUrl":"10.1016/j.heliyon.2024.e40130","url":null,"abstract":"<p><p>The development of composite materials using natural fibers has garnered significant global research interest. Banana fibers, due to their abundant availability and rapid growth cycle, present a promising option for composite material development. When combined with synthetic fibers to form hybrid composites, the resulting material may exhibit significantly improved properties, which is desirable for automotive body manufacturing. The hybrid properties of such composites, however, remain largely unexplored and require thorough evaluation. This study investigates the mechanical performance of hybrid laminated composites fabricated from banana and woven glass fibers bonded with epoxy resin. The composites were produced using non-crimp banana (B) fiber and woven glass (WG) fiber fabrics through the hand lay-up process with four distinct stacking sequences: [WG/B-0⁰/B-0⁰/WG], [WG/B-0⁰/B-45⁰/WG], [WG/B-0⁰/B-60⁰/WG], and [WG/B-0⁰/B-90⁰/WG]. Comprehensive mechanical testing, including tensile, flexural, impact, and hardness tests, along with environmental testing (water diffusion) was conducted in accordance with ASTM standards. Results indicated that the [WG/B-0⁰/B-0⁰/WG] configuration exhibited the highest tensile strength, while the [WG/B-0⁰/B-60⁰/WG] configuration achieved superior flexural strength. The [WG/B-0⁰/B-45⁰/WG] configuration demonstrated the highest impact strength and energy absorption. Rockwell hardness testing revealed that the average hardness numbers for all orientations were approximately 79, which is considered moderate for composite materials. Water absorption tests showed maximum water saturation in [WG/B-0⁰/B-90⁰/WG] of ∼5.5 %, where the other laminates had water saturation between 4.5 and 4.9 %. The microscopic analysis of the [WG/B-0⁰/B-45⁰/WG] laminate suggests fiber-matrix debonding and fiber pull-out as the major cause of failure under tensile and flexural loading. These findings suggest that the hybrid laminated composites, particularly the [WG/B-0⁰/B-0⁰/WG] and [WG/B-0⁰/B-45⁰/WG] configurations, exhibit mechanical properties suitable for automotive body applications.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 21","pages":"e40130"},"PeriodicalIF":3.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}