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Development and validation of a nomogram model for predicting the risk of hypertension in Bangladesh. 开发并验证用于预测孟加拉国高血压风险的提名图模型。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-08 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40246
Merajul Islam, Jahangir Alam, Sujit Kumar, Ariful Islam, Muhammad Robin Khan, Symun Rabby, N A M Faisal Ahmed, Dulal Chandra Roy
{"title":"Development and validation of a nomogram model for predicting the risk of hypertension in Bangladesh.","authors":"Merajul Islam, Jahangir Alam, Sujit Kumar, Ariful Islam, Muhammad Robin Khan, Symun Rabby, N A M Faisal Ahmed, Dulal Chandra Roy","doi":"10.1016/j.heliyon.2024.e40246","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40246","url":null,"abstract":"<p><strong>Background and objectives: </strong>Hypertension (HTN) is a leading cause of non-communicable disease in low- and middle-income countries, including Bangladesh. Thus, the objectives of this study were to investigate the associated risk factors for HTN and develop with validate a monogram model for predicting an individual's risk of HTN in Bangladesh<b>.</b></p><p><strong>Materials and methods: </strong>This study exploited the latest nationally representative cross-sectional BDHS, 2017-18 data, which consisted of 6569 participants. LASSO and logistic regression (LR) analysis were performed to reduce dimensionality of data, identify the associated risk factors, and develop a nomogram model for predicting HTN risk in the training cohort. The discrimination ability, calibration, and clinical effectiveness of the developed model were evaluated using validation cohort in terms of area under the curve (AUC), calibration plot, decision curve analysis, and clinical impact curve analysis.</p><p><strong>Results: </strong>The combined results of the LASSO and LR analysis demonstrated that age, sex, division, physical activity, family member, smoking, body mass index, and diabetes were the associated risk factors of HTN. The nomogram model achieved good discrimination ability with AUC of 0.729 (95 % CI: 0.685-0.741) for training and AUC of 0.715 (95 % CI: 0.681-0.729)] for validation cohort and showed strong calibration effects, with good agreement between the actual and predicted probabilities (p-value = 0.231).</p><p><strong>Conclusion: </strong>The proposed nomogram provided a good predictive performance and can be effectively utilized in clinical settings to accurately diagnose hypertensive patients who are at risk of developing severe HTN at an early stage in Bangladesh.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40246"},"PeriodicalIF":3.4,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovative techniques for developing hybrid yarns using different core insertion methods: A comparative study. 使用不同的插芯方法开发混合纱线的创新技术:比较研究。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-08 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40170
Onur Duru, Ahsan Habib, Osman Babaarslan
{"title":"Innovative techniques for developing hybrid yarns using different core insertion methods: A comparative study.","authors":"Onur Duru, Ahsan Habib, Osman Babaarslan","doi":"10.1016/j.heliyon.2024.e40170","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40170","url":null,"abstract":"<p><p>Elastane fibers, in particular, have gained an important share in the production of elastic yarn. This research aims to evaluate innovative methods for developing hybrid yarns (dual core) by integrating core elements in various configurations to show the influence of different core-inserting techniques on yarn characteristics. The research developed a modified pulley (W-grooved roller) to insert core elements side by side along with the existing method during the yarn manufacturing process. Ne 16/1 yarn (dual core) was manufactured using five different core inserting techniques with cotton roving, polybutylene terephthalate (PBT), and elastane (Lycra®). The characteristics of the produced yarns were analyzed using standard testing methods. Statistical analysis was performed to determine significant variations in yarn properties using one-way MANOVA and the MOORA method was employed to determine the most suitable yarn configuration. The results indicate that yarn manufactured by inserting core components side by side significantly enhances the expected characteristics of hybrid yarns. Yarns manufactured by inserting core components side by side show higher strength, elongation, and lower hairiness values. This research introduces a novel technique for producing dual-core yarns by side-by-side insertion of core elements contributing to the development of innovative hybrid yarns.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40170"},"PeriodicalIF":3.4,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined effect of compressing fresh concrete and curing regime on bonding performance of high strength repair mortar. 压缩新拌混凝土和养护制度对高强度修补砂浆粘结性能的综合影响
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-08 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40242
Parisa Bahri, Mahmoud Naderi
{"title":"Combined effect of compressing fresh concrete and curing regime on bonding performance of high strength repair mortar.","authors":"Parisa Bahri, Mahmoud Naderi","doi":"10.1016/j.heliyon.2024.e40242","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40242","url":null,"abstract":"<p><p>High strength concrete (HSC) is highly appropriate for the retrofitting and rehabilitation of reinforced concrete structures due to its low permeability and high bonding strength. However, its low workability and sensitivity to curing conditions pose significant challenges for its implementation in such projects. This study introduces a novel technique to overcome the workability barrier of HSC while enhancing its bonding strength under various curing conditions. To achieve this, four different pressures (0, 0.87, 2.61, and 5.23 MPa) were applied to fresh high strength repair mortar (HSRM) and HSC for durations of 2, 4, and 8 h. Subsequently, different curing methods, including the wet sack method, steam curing method, and the use of curing compounds, were employed. The modulus of elasticity and compressive strength of HSC, in addition to bonding performance between substrate HSC and 28-day compressed HSRM, were evaluated using the \"friction-transfer\" and \"twist-off\" techniques, which are standard techniques for measuring the bonding strength of concrete both in the laboratory and in-situ. Also, to further assess the effect of curing regime and pressure on the microstructures of HSRM, SEM images of 28-day HSRM specimens were collected. The results indicated that increasing the pressure to 5.23 MPa and extending the duration to 8 h enhanced the ultimate torsional shear strength between HSRM and substrate HSC by an average of 174%. Additionally, the mechanical properties of HSC were considerably enhanced by applying 5.23 MPa pressure over 8 h. It is worth mentioning that the bonding strength between HSRM and substrate HSC without curing was highly affected by the duration of pressure application compared to the three investigated curing methods. The wet sack curing method was found to be the most effective for enhancing the degree of hydration and increasing the failure torsional shear stress of compressed HSRM specimens.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40242"},"PeriodicalIF":3.4,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental assessment of using phase change materials in vapor compression refrigeration systems for condenser pre-cooling. 在蒸汽压缩制冷系统中使用相变材料进行冷凝器预冷的实验评估。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-08 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40259
Alireza Riahi, Mohammad Behshad Shafii
{"title":"Experimental assessment of using phase change materials in vapor compression refrigeration systems for condenser pre-cooling.","authors":"Alireza Riahi, Mohammad Behshad Shafii","doi":"10.1016/j.heliyon.2024.e40259","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40259","url":null,"abstract":"<p><p>The primary objective of this investigation is to empirically assess a new vapor compression cycle while employing phase change material (PCM) energy storage. During off-peak periods, the PCM undergoes charging, and during on-peak hours, it is discharged to cool the refrigerant entering the condenser, thereby enhancing the condenser's overall performance. In contrast to previous studies that exclusively examined the charging or discharging processes of air conditioning (AC) units, this research delves into the entire 24-h charge and discharge cycle. The proposed system is subjected to testing under identical conditions, both without PCM (conventional mode) and with a PCM storage tank, throughout a 24-h period. The PCM storage tank, which utilizes water as its phase change medium, possesses a volume of approximately 300 L and starts at an initial temperature of 25 °C. The outcomes of the study demonstrate notable improvements when incorporating the PCM storage tank. Specifically, the daily coefficient of performance (COP) increases by approximately 7 %, rising from 2.17 to 2.33. Additionally, it leads to a reduction in both the daily available cooling load and daily compressor energy consumption, with decreases of approximately 3.7 % (from 58.4 to 56.2 kWh) and 10.3 % (from 26.9 to 24.1 kWh), respectively.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40259"},"PeriodicalIF":3.4,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward high-integrity forest carbon market of ethnic minority groups in Dak Lak province, Vietnam. 越南达乐省少数民族群体的高完整性森林碳市场。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-07 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e39998
Nguyen Dinh Tien, Tran Thi Huong, Tran Nhat Lam Duyen, Nguyen Thi Hong Hanh, Nguyen Thi Thanh Huyen, Nguyen Thi Oanh
{"title":"Toward high-integrity forest carbon market of ethnic minority groups in Dak Lak province, Vietnam.","authors":"Nguyen Dinh Tien, Tran Thi Huong, Tran Nhat Lam Duyen, Nguyen Thi Hong Hanh, Nguyen Thi Thanh Huyen, Nguyen Thi Oanh","doi":"10.1016/j.heliyon.2024.e39998","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e39998","url":null,"abstract":"<p><p>Forest carbon markets have demonstrated numerous benefits across economic, social, and environmental dimensions, while also advancing sustainable development goals. This study examines the primary policy mechanisms and conditions related to the development of high-integrity forest carbon markets in Dak Lak province, Vietnam. Utilizing a combination of SWOT analysis and the DPSIR framework, the study provides a comprehensive evaluation of the opportunities, challenges, driving forces, pressures, potential impacts, and responses associated with developing these markets. The Gold Standard method was also employed to estimate the potential contribution to carbon emission reductions through the new forest planting programs in the province. Data analysis from 202 households and in-depth interviews with fifteen experts revealed that local residents have limited information about the forest carbon market. While forest management officials at various levels are aware of the market, there is a lack of specific guidance, limited participation in training sessions and workshops, and insufficient instructional materials. Dak Lak holds significant potential for carbon emission reductions, with an estimated average forest carbon storage capacity of 7.5 tCO<sub>2</sub>/ha/year for an afforestation/reforestation (A/R) carbon project. This initiative is projected to contribute approximately $753,972 annually to the province's GRDP and generate 280 jobs for local communities. However, the technical and financial resources are challenging in the province. The study identifies critical issues and proposes appropriate solutions to support Dak Lak in developing high-integrity forest carbon markets in alignment with the national roadmap, ultimately contributing to the achievement of sustainable development goals.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e39998"},"PeriodicalIF":3.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development, validation, and application of a South African Dietary Polyphenol Data Quality Assessment Tool. 南非膳食多酚数据质量评估工具的开发、验证和应用。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-07 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40231
Malory R Jumat, Kwaku G Duodu, Averalda E van Graan
{"title":"Development, validation, and application of a South African Dietary Polyphenol Data Quality Assessment Tool.","authors":"Malory R Jumat, Kwaku G Duodu, Averalda E van Graan","doi":"10.1016/j.heliyon.2024.e40231","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40231","url":null,"abstract":"<p><p>There is a wealth of South African scientific literature studying and reporting on dietary polyphenols in research articles and academic literature. The evaluation of data quality is critical to ensure polyphenol data compiled from various scientific journals and academic texts are acceptable in terms of compilation standards. This study aimed to develop, validate, and apply a country specific South African dietary polyphenol data quality assessment tool (SADPDQAT). The evaluation tool considered nine evaluation categories with a maximum score of 5. For each literature source assessed, a quality score and confidence code was assigned. Validation analysis revealed generally consistent results between raters with an average percentage agreement of 65 %, no scores falling outside of Bland-Altman limits of agreement and a moderate internal consistency α = 0.533 which was improved to 0.616. Applying the tool to 383 scientific studies showed that most literature obtained a quality score between 70 and 79 % resulting in a confidence code of \"B\" (n = 166, 43 %) and a score between 60 and 69 % resulting in a confidence code of \"C\" (n = 125, 33 %). The SADPDQAT can be used to evaluate a variety of dietary polyphenol containing literature and aids in setting priorities for further research in this area.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40231"},"PeriodicalIF":3.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pan-cancer analysis of IRF1 focusing on prognostic and immunological roles in non-small cell lung cancer. 对 IRF1 进行泛癌症分析,重点关注其在非小细胞肺癌中的预后和免疫学作用。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-07 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e39861
Weiling Sun, Kui Cao, Siran Wang, Mengdi Lu, Jianqun Ma, Chunlong Wu, Yanbin Zhao
{"title":"Pan-cancer analysis of IRF1 focusing on prognostic and immunological roles in non-small cell lung cancer.","authors":"Weiling Sun, Kui Cao, Siran Wang, Mengdi Lu, Jianqun Ma, Chunlong Wu, Yanbin Zhao","doi":"10.1016/j.heliyon.2024.e39861","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e39861","url":null,"abstract":"<p><p>Interferon regulatory factor 1 (IRF1) significantly affects tumour occurrence and development. This study aimed to analyse its function as a pan-cancer prognostic indicator. We compared IRF1 expression and prognostic significance in normal and tumour samples from different databases. Accordingly, we performed <i>in vitro</i> experiments and immunohistochemistry (IHC) to investigate the role of IRF1 in non-small cell lung cancer (NSCLC). Our findings indicate that IRF1 expression is significantly correlated with prognosis, the tumour microenvironment, and immune cell infiltration. Furthermore, receiver operating characteristic (ROC) analysis revealed that IRF1 had high accuracy in distinguishing cancerous tissues from normal ones. Notably, IRF1 expression was linked to immune-related and immune checkpoint genes. Cell proliferation, invasion, and migration were significantly related to IRF1 expression. IHC indicated that IRF1 was downregulated in NSCLC tissues. Our study provides comprehensive bioinformatic analysis and experimental verification of IRF1, suggesting its potential as a prognostic biomarker in cancer.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e39861"},"PeriodicalIF":3.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment on major browse feed resources and determine their chemical composition in Korhaye zone, Somali Region, Ethiopia. 评估埃塞俄比亚索马里地区科尔哈耶区的主要草食资源并确定其化学成分。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-07 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40178
Wondimagegn Tadesse, Kibebew Babege, Sale Wandara
{"title":"Assessment on major browse feed resources and determine their chemical composition in Korhaye zone, Somali Region, Ethiopia.","authors":"Wondimagegn Tadesse, Kibebew Babege, Sale Wandara","doi":"10.1016/j.heliyon.2024.e40178","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40178","url":null,"abstract":"<p><p>Assessment of major browse feed resources and determine the chemical composition of selected browse feed resource in <i>Korahay Zone, Somali Regional State, was the aim of this study</i>. Kebeles and the household heads were selected purposively in study area. The samples of fresh leaves (800 g) of selected browse species were collected to determine chemical compositions. SPSS version 20 was used for data analysis. The feed related constraints were ranked and analyzed by the ranking index. The current result indicated that, total of 22 trees, 6 shrub, 4 bush and 6 herbaceous species used as feed for livestock in dry and/or wet season were identified in the study area. DM, OM, CP, NDF, ADF, ADL and Ash of Dobera glabra, Grewia bicolor, Boscia minimfolia, Prosopis juliflora, Acacia Senegal, Unidentified (Alankhayir), Unidentified (Geed chic) were determined in current laboratory analysis. DM, OM, CP, NDF, ADF, ADL and Ash of Dobera glabra was 92.8 %, 94.28 %, 14.4 %, 42.5 %, 26.9 %, 5.22 % and 5.73 % respectively. Finally, feed quality and quantity, drought, invasive species and ecological deterioration were identified as major constraints of feed resources in study area. Due to this, intervention and further study should be conducted to tackle existing feed and feed related issues.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40178"},"PeriodicalIF":3.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Substantial projections from the lateral division of the lateral habenula to the dorsal raphe nucleus and from the lateral habenula to the contralateral ventral tegmental area. 从外侧哈文神经节的外侧分部向背侧剑突核以及从外侧哈文神经节向对侧腹侧被盖区发出大量投射。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-07 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40234
Tomoya Nakamura, Trang Van Thi Nguyen, Takumi Maeda, Hiroyuki Ichijo
{"title":"Substantial projections from the lateral division of the lateral habenula to the dorsal raphe nucleus and from the lateral habenula to the contralateral ventral tegmental area.","authors":"Tomoya Nakamura, Trang Van Thi Nguyen, Takumi Maeda, Hiroyuki Ichijo","doi":"10.1016/j.heliyon.2024.e40234","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40234","url":null,"abstract":"<p><p>The lateral habenular nucleus (LHb) projects to the dorsal raphe nucleus (DRN) and ventral tegmental area (VTA). Prior studies have reported that the medial division of the LHb (LHb-m) mainly projects to the DRN, while the LHb mainly projects to the ipsilateral VTA; however, due to only a few studies of projection ratio analysis, the degree of projection of minor and major pathways remains unclear, and the potential significance of minor pathways may be overlooked. After injecting the retrograde tracer into the mice DRN, the proportion of labeled neurons was 63.50 % in the LHb-m and 36.50 % in the lateral division of the LHb (LHb-l). The proportion distributions of labeled neurons were 26.90 % in the anterior LHb-m and 73.10 % in the posterior LHb-m. When the retrograde tracer was injected into the VTA, the percentage of labeled neurons was 64.85 % in the ipsilateral LHb and 35.15 % in the contralateral LHb. The number of cells projecting from anterior and posterior ipsilateral LHb-m to the VTA varied among the individual injection sites. Our quantitative analysis with multiple subjects showed that the projections from LHb-l to DRN and from LHb to contralateral VTA were indeed minor pathways, however, they were substantial. These results provide an anatomical basis for the potential importance of minor pathways projected from the LHb to the VTA and DRN and for the difference in the densities of neurons projecting from the anterior and posterior LHb-m to the DRN.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40234"},"PeriodicalIF":3.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modification mechanism of Te and morphology evolution of primary Mg2Si in an Al-20Mg2Si alloy. Al-20Mg2Si 合金中原生 Mg2Si 的 Te 变化机理和形态演变。
IF 3.4 3区 综合性期刊
Heliyon Pub Date : 2024-11-07 eCollection Date: 2024-11-30 DOI: 10.1016/j.heliyon.2024.e40141
Chao Li, Zhaohua Wang, Yongfeng Zhao, Junli Du, Yunrui Ma, Jiacheng Li, Fei Sun
{"title":"Modification mechanism of Te and morphology evolution of primary Mg<sub>2</sub>Si in an Al-20Mg<sub>2</sub>Si alloy.","authors":"Chao Li, Zhaohua Wang, Yongfeng Zhao, Junli Du, Yunrui Ma, Jiacheng Li, Fei Sun","doi":"10.1016/j.heliyon.2024.e40141","DOIUrl":"https://doi.org/10.1016/j.heliyon.2024.e40141","url":null,"abstract":"<p><p>In the present work, the modification effect of Te and the corresponding growth process of Mg<sub>2</sub>Si were clarified. With 0.5 wt% Te addition, the dendritic primary Mg<sub>2</sub>Si transformed to polygons, accompanied by a reduction in size from over ∼165 μm-∼18 μm. However, 2.0 wt% Te addition resulted in degradation of modification effect, and the morphology of Mg<sub>2</sub>Si changed to dendrite. Three-dimensional morphology of primary Mg<sub>2</sub>Si indicated that Te altered the morphology of primary Mg<sub>2</sub>Si from dendrites to polyhedrons surrounded by {111} and {100}. The modification mechanism of Te can be attributed to the heterogeneous nucleation and the doping of Te during the growth process of primary Mg<sub>2</sub>Si, which greatly contributed to dimension decrease and morphology evolution of primary Mg<sub>2</sub>Si respectively. With Te corporation, the relative surface energy between the {100} and {111} (r) drops, contributing to the exposure of {100}. Our work shows that the solute concentration under non-equilibrium solidification plays an important role in determining the final morphology of Mg<sub>2</sub>Si. The local segregation of Mg and Si solutes results in the degradation of dendrite arms along certain directions during the initial stage of crystal growth. Combined with the modifying effect of Te, which alters the surface energy of the crystal, the final crystal morphology deviates from its equilibrium state. Our study demonstrates that ultimate morphology and dimensions of primary Mg<sub>2</sub>Si can be determined simultaneously with the addition of certain modifiers, which can be achieved by regulating the growth and nucleation of Mg<sub>2</sub>Si at the same time.</p>","PeriodicalId":12894,"journal":{"name":"Heliyon","volume":"10 22","pages":"e40141"},"PeriodicalIF":3.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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