Heart rhythm最新文献

{"title":"Device-related complications in a national pediatric CIED cohort stratified after age and implantation technique.","authors":"Jani Thuraiaiyah, Annette Schophuus Jensen, Ole De Backer, Chee Woon Lim, Lars Idorn, Frederikke Noerregaard Jakobsen, Troels Hoejsgaard Joergensen, Michael Rahbek Schmidt, Morten Smerup, Jens Brock Johansen, Sam Riahi, Lars Sondergaard, Jens Cosedis Nielsen, Berit Thornvig Philbert, Christian Jons","doi":"10.1016/j.hrthm.2025.03.1986","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1986","url":null,"abstract":"<p><strong>Background: </strong>Cardiac implantable electronic devices (CIED) can be implanted epicardial or transvenous in children. Both techniques involve procedure-specific complications, and the evidence is scares for which technique to choose for different ages.</p><p><strong>Objectives: </strong>We aimed to characterize a complete national pediatric cohort with a de-novo CIED implantation and compare the risk and causes of re-intervention between transvenous and epicardial CIED recipients.</p><p><strong>Methods: </strong>This retrospective nationwide cohort study included all Danish children receiving a CIED aged≤15 years from 1977 to 2021. The outcomes included time to first re-intervention stratified by age and implantation technique. Re-intervention was either due to battery depletion, lead- or generator complication.</p><p><strong>Results: </strong>A total of 376 children received epicardial (n=131, 35%) and transvenous (n=245, 65%) CIEDs with a median follow-up of 14 (IQR 6-21) years. Median age was 6 (IQR 1-11) years. For epicardial recipients, the complication-driven re-intervention was equal across age groups (p=0.10), while among transvenous recipients, the risk was significantly lower with increasing age (p<0.001). Age-specific risk analyses revealed different risks for children aged <1 year, 1-8 years, and 9-15 years (P_interaction<0.001). For children<1 year, a complication-driven re-intervention was more frequent for transvenous versus epicardial recipients (p<0.001), while in children aged 9-15 years, the opposite was observed (p=0.02).</p><p><strong>Conclusions: </strong>Transvenous implantation in children <1 year and epicardial implantation in children 9-15 years were associated with higher risk of CIED-related complication leading to re-intervention, whereas for children aged 1 to 8 years, complication risk was similar between implantation techniques.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking AF Ablation Success by Integrating AF Burden into Time-to-Event Analysis: the Burden-Survival Curve.","authors":"Mattias Duytschaever, Alexandre Almorad, Milad El Haddad, Jean-Benoit Le Polain de Waroux, Sebastien Knecht, Rene Tavernier","doi":"10.1016/j.hrthm.2025.03.1984","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1984","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Substrate Characterization and Outcomes of Catheter Ablation of Ventricular Tachycardia in Patients with Non-Ischemic Dilated Cardiomyopathy and Isolated Apical Scar.","authors":"Yi-Wen Becky Liao, Bryan Baranowski, Mandeep Bhargava, Thomas D Callahan, Mina K Chung, Jeffery Courson, Thomas J Dresing, Nolan Hight, Ayman Hussein, Mohamed H Kanj, Arshneel S Kochar, Robert A Koeth, Justin Lee, David Martin, Kenneth Mayuga, Shady Nakhla, John Rickard, Walid I Saliba, Tyler Taigen, Niraj Varma, Tom Kai Ming Wang, Oussama M Wazni, Jakub Sroubek, Koji Higuchi, Pasquale Santangeli","doi":"10.1016/j.hrthm.2025.03.1985","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1985","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VENTRICULAR ARRHYTHMIAS DURING EXERCISE TESTING IN PEDIATRIC PATIENTS WITH ARRHYTHMOGENIC CARDIOMYOPATHY AT FIRST PRESENTATION AND WITH DIFFERENT VENTRICULAR INVOLVEMENT Correlation between arrhythmic expression and phenotype: is really possible?","authors":"Marianna Cicenia, Michele Lioncino, Nicoletta Cantarutti, Irma Battipaglia, Aurelio Secinaro, Rachele Adorisio, Anwar Baban, Massimo Stefano Silvetti, Fabrizio Drago","doi":"10.1016/j.hrthm.2025.03.1983","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1983","url":null,"abstract":"<p><strong>Background: </strong>Ventricular arrhythmias (VAs) may be the first clinical manifestation in pediatric patients with arrhythmogenic cardiomyopathy (ACM). The arrhythmogenicity of exercise testing (ET) remains unclear.</p><p><strong>Objective: </strong>Describe the arrhythmogenicity of ETs in pediatric early ACM.</p><p><strong>Methods: </strong>Pediatric patients diagnosed with definite ACM were enrolled. ET results at the first presentation and off of therapy were analyzed. Comparison with a control group [premature ventricular complexes (PVCs) without structural heart disease] was performed.</p><p><strong>Results: </strong>At baseline, VAs were observed in 20 (80%) patients: 3 had non-sustained ventricular tachycardia (ns-VT) and 17 isolated PVCs. No PVC morphology was significantly more prevalent among ACM phenotypes. At peak exercise, VAs were present in 40% of patients and 10% of controls. During recovery, VAs occurred in 17 (68%) and 4 (8%) of controls. Polymorphism and ns-VTs during recovery were more prevalent in biventricular-ACM (BIV-ACM) than non-biventricular-ACM (p=0.03; p=0.03). Irregular VAs were present in 80% of BIV-ACM. Compared with controls, PVCs with LBBB/superior axis at baseline and VAs during recovery were significantly associated with the probability of having ACM (p=0.0038, p=<0.0001, respectively).</p><p><strong>Conclusions: </strong>VAs behavior during ET at the beginning of ACM is highly variable and suppression during exercise is not uncommon. Nevertheless, the presence at the peak of exercise is more common in ACM patients. Baseline LBBB superior axis PVCs and VAs during recovery correlate with the presence of ACM. VAs morphology and ET behavior cannot predict ACM phenotype. Polymorphism and ns-VTs are more prevalent in patients with BIV-ACM.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Dedicated Radiofrequency Microcatheter Assembly For Trans-Right Atrial Appendage Pericardial Carbon Dioxide Insufflation To Facilitate Epicardial Access.","authors":"Ioan Liuba, Arwa Younis, Paresh Vasandani, Jakub Sroubek, Koji Higuchi, Justin Lee, Walid Saliba, Alison Krywanczyk, Shady Nakhla, Mandeep Bhargava, Ayman Hussein, Mohamed Kanj, Samir Kapadia, Oussama Wazni, Pasquale Santangeli","doi":"10.1016/j.hrthm.2025.03.1977","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1977","url":null,"abstract":"<p><strong>Background: </strong>Trans-right atrial appendage (RAA) pericardial insufflation of CO₂ can improve safety of percutaneous epicardial access. Dedicated device solutions for safe, effective and standardized microperforation are needed.</p><p><strong>Objectives: </strong>We evaluated the efficacy and safety of a novel radiofrequency (RF)-powered microcatheter specifically designed to facilitate trans-RAA exit to the pericardial space.</p><p><strong>Methods: </strong>Four healthy swine underwent repeated RAA and left atrial appendage (LAA) perforations to access the pericardial space via a dedicated 1.8 Fr microcatheter with an RF tip. Perforations were obtained by delivering short bursts of RF energy (20-25 W, <1 second, \"cut\" mode). Animals were sacrificed immediately after the experiment and the hearts were assessed by gross pathology and histology.</p><p><strong>Results: </strong>A median number of 7 microperforations/animal (interquartile range, IQR: 7-9) were performed in the RAA and 3/animal (IQR: 2-3) in the LAA. In one animal, a postero-lateral RA perforation was also performed. All perforations and microcatheter advancements in the pericardial space were successful (<5 seconds). There was no evidence of pericardial effusion by intracardiac echocardiography and no hemodynamic changes with any of the perforations. On pathology, no pericardial effusion was noted and the atrial perforations could be identified as punctate red areas (0.5-1 mm) in 28/31 targeted RAA sites and 5/8 targeted LAA sites. Histology showed central full-thickness defects with associated acute thrombus formation and surrounded by a small rim of contraction bands necrosis.</p><p><strong>Conclusions: </strong>In this pre-clinical study, repeated trans-RAA/LAA perforations with pericardial space access were successfully obtained with a dedicated RF-tip 1.8 Fr microcatheter with no evidence of significant pericardial bleeding.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Left Atrial Thrombus in Patients with Atrial Flutter in Comparison to Atrial Fibrillation.","authors":"Maciej T Wybraniec, Fabian Wesołek, Przemysław Szyszka, Małgorzata Cichoń, Michał Orszulak, Magdalena Mizia-Szubryt, Michał Wita, Monika Gawałko, Monika Budnik, Beata Uziębło-Życzkowska, Paweł Krzesiński, Katarzyna Starzyk, Beata Wożakowska-Kapłon, Ludmiła Daniłowicz-Szymanowicz, Damian Kaufmann, Maciej Wójcik, Robert Błaszczyk, Jarosław Hiczkiewicz, Jan Budzianowski, Katarzyna Łojewska, Katarzyna Kosmalska, Marcin Fijałkowski, Anna Szymańska, Anna Wiktorska, Maciej Haberka, Michał Kucio, Błażej Michalski, Karolina Kupczyńska, Anna Tomaszuk-Kazberuk, Katarzyna Wilk-Śledziewska, Renata Wachnicka-Truty, Marek Koziński, Paweł Burchardt, Katarzyna Mizia-Stec, Agnieszka Kapłon-Cieślicka","doi":"10.1016/j.hrthm.2025.03.1980","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1980","url":null,"abstract":"<p><strong>Background: </strong>Atrial flutter (AFL) and atrial fibrillation (AF) are believed to carry the same risk of systemic thromboembolism however there is paucity of data concerning such risk in patients with AFL in comparison to AF.</p><p><strong>Objective: </strong>The aim of the study was to evaluate the prevalence of left atrial thrombus (LAT) on transesophageal echocardiography (TEE) in patients with AFL in comparison to AF depending on anticoagulation status.</p><p><strong>Methods: </strong>The study is the sub-analysis of a multicenter, prospective Left Atrial Thrombus on Transesophageal Echocardiography (LATTEE) registry, which enrolled AF and AFL patients referred for ablation or electrical cardioversion regardless of oral anticoagulation (OAC) use. All patients underwent pre-procedural TEE to assess the primary endpoint of the LAT presence.</p><p><strong>Results: </strong>A total of 3109 patients (AF n=2577; AFL n=532) were included in the study. Therapeutic OAC, defined as anticoagulation lasting at least three weeks, was used by 89.8% of patients in the AF subgroup and 82.5% in the AFL subgroup (p<0.001). LAT was present in 8.3% of patients with AF and 6.8% with AFL, regardless of therapeutic OAC use (p=0.235). In patients on therapeutic OAC, LAT was present in 7.6% in AF group and 5.7% in AFL subgroup (p=0.167), while in patients without therapeutic OAC in 14.9% in AF subgroup and 11.8% in AFL subgroup (p=0.459).</p><p><strong>Conclusion: </strong>The risk of thrombus formation in AFL seems to be similar to AF, supporting similar recommendations concerning OAC use.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transvenous extraction of quadripolar coronary sinus pacing leads.","authors":"Ethan S Wagner, Robert K Lewis, Sean D Pokorney, Donald D Hegland, Jonathan P Piccini","doi":"10.1016/j.hrthm.2025.03.1979","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1979","url":null,"abstract":"<p><strong>Background: </strong>Quadripolar coronary sinus (CS) leads are commonly employed to achieve left ventricular pacing. There are limited data on extraction of these leads relative to traditional unipolar or bipolar CS pacing leads.</p><p><strong>Objective: </strong>To examine the safety and efficacy of quadripolar CS lead extraction and CS lead reimplantation, and to compare outcomes with extraction of non-quadripolar CS leads.</p><p><strong>Methods: </strong>Patients who underwent extraction of CS leads between 2013 and 2024 were included. Outcomes of interest included rates of complete CS lead removal, complete procedural success, major adverse events, and successful reimplantation in the CS.</p><p><strong>Results: </strong>A total of 182 patients were included (n = 102 quadripolar leads and n = 80 non-quadripolar leads). The mean patient age was 68.0 ± 11.6 years and 22% were female. The mean CS lead age was significantly lower in the quadripolar group (3.0 ± 2.7 years vs. 8.2 ± 4.3 years, p < 0.001). The complete procedural success rate was significantly higher in the quadripolar group (99% vs. 90%, p = 0.01); there was no difference between groups after accounting for lead age. There was no significant difference in complete CS lead removal rates between groups (99% vs. 95%, p = 0.17). Two major adverse events occurred in the non-quadripolar group and were directly related to lead extraction. In the quadripolar group, manual traction alone was successful in 59%, laser sheaths were used in 39%, and rotational cutting tools were used in 9%. In the non-quadripolar group, manual traction alone was successful in 19%, laser sheaths were used in 79%, and rotational cutting tools were used in 26%. There was no significant difference in reimplantation success rates between groups (82% vs. 90%, p = 0.30).</p><p><strong>Conclusion: </strong>Quadripolar CS lead extraction had a high success rate and low rate of major adverse events. Reimplantation in the CS was possible with a good success rate but was often limited by CS branch stenosis or occlusion.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse right coronary artery spasm occurring forty-five minutes post pulsed field ablation for atrial fibrillation.","authors":"Vishal Luther, Justin Chiong, Catherine James, Simon Modi, Dhiraj Gupta, John Hung","doi":"10.1016/j.hrthm.2025.03.1978","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1978","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Septal Vascular Injury and Perforation in Left Bundle Branch Area Pacing: Evaluating Septal Integrity using an Institutional Protocol.","authors":"Emine Özpak, Tijs Tournoy, Thomas Van Overmeiren, Frederic Van Heuverswyn, Frank Timmermans, Jan De Pooter","doi":"10.1016/j.hrthm.2025.03.1982","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1982","url":null,"abstract":"<p><strong>Background: </strong>Left bundle branch area pacing (LBBAP) involves deep septal lead deployment to capture the left bundle branch (LBB) or adjacent myocardium, which could compromise the septum's structural integrity or pose injury to the septal vasculature. The potential long-term effects of these complications remain unclear.</p><p><strong>Objective: </strong>To evaluate acute and long-term outcomes of septal injury during LBBAP using a structured institutional protocol.</p><p><strong>Methods: </strong>Adult patients receiving LBBAP between March 2019 and October 2024 were assessed for septal complications, including septal perforation, septal venous channel perforation (SVCP), septal coronary artery fistula (SCAF), and septal hematomas. The protocol included intraprocedural septography and post-procedural echocardiography, including visual assessment and strain imaging, to assess global and septal kinetics.</p><p><strong>Results: </strong>Among 636 patients, 32 (5%) experienced septal complications: 26 septal perforations (4%), 3 SVCP's (0,5%) and 3 SCAF's (0,5%). All perforations and SVCP's were identified during implant, while SCAF's were diagnosed post-procedurally. All complications were asymptomatic with no adverse clinical outcomes. Septal kinetics remained unaffected, as peak septal strain values showed no significant differences before and after implantation (from 20,4 ± 3,6% to 21,3 ± 3,3%; p=0,16). No late perforations or ventricular septal defects were observed. Two SCAF's healed spontaneously, and one persisted asymptomatically. Key pacing characteristics and left ventricular ejection fraction remained stable throughout follow-up.</p><p><strong>Conclusion: </strong>Septal perforations are the most frequent septal complication and are easily detected. Septal vascular injuries can be detected using dedicated protocols, but occur rarely.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes and anticoagulant management for new-onset atrial fibrillation in patients with ST-elevation myocardial infarction following primary percutaneous coronary intervention: Findings from a national multicenter registry and meta-analysis.","authors":"Can Zhou, Minghui Zhang, Zixu Zhao, Enze Li, Yichen Zhao, Hong Wang, Wei Luo, Keyang Zheng, Yu Liu, Chengqian Yin, Xinyong Zhang, Hai Gao, Xiaotong Hou, Dong Zhao, Changsheng Ma","doi":"10.1016/j.hrthm.2025.02.036","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.02.036","url":null,"abstract":"<p><strong>Background: </strong>Little is known about the risk factors and prognosis of new-onset atrial fibrillation (NOAF) in patients with primary percutaneous coronary intervention (PCI).</p><p><strong>Objective: </strong>The purpose of this study was to assess the prevalence and prognosis of NOAF after PCI and the effects of anticoagulation on clinical outcomes.</p><p><strong>Method: </strong>Using data from the CCC-ACS (Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome) project, ST-elevation myocardial infarction (STEMI) patients undergoing PCI were stratified into 2 groups: with NOAF or without any atrial fibrillation. Multivariable logistic regression was used to identify NOAF predictors, and propensity-score matching estimated associations between NOAF and in-hospital outcomes. A meta-analysis was also performed by pooling our results with literature data.</p><p><strong>Results: </strong>Of 19,288 STEMI patients undergoing PCI, 1.3% (n = 253) experienced NOAF. Independent risk factors were age ≥65 years, history of hypertension, stroke, heart failure, Killip class IV, and right coronary artery as the culprit artery. NOAF was associated with a higher risk of all-cause mortality (hazard ratio [HR] 2.26, 95% confidence interval [CI] 1.08-4.71), heart failure (HR 4.29, 95% CI 2.81-6.55), cardiogenic shock (HR 4.30, 95% CI 2.28-8.13), in-stent thrombosis (HR 6.04, 95% CI 1.71-21.45), and major bleeding (HR 2.86, 95% CI 1.44-5.66) during hospitalization. Meta-analysis found that NOAF had a higher risk of in-hospital stroke (odds ratio 3.33, 95% CI 1.73-6.43). In-hospital use of anticoagulants was associated with lower rates of all-cause mortality but similar rates of major bleeding in NOAF patients.</p><p><strong>Conclusion: </strong>Our study suggests NOAF following PCI is uncommon but associated with poor in-hospital prognosis. Findings support the use of anticoagulants in these patients during hospitalization.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}