Heart rhythmPub Date : 2025-03-28DOI: 10.1016/j.hrthm.2025.02.001
David G. Benditt MD, FHRS, CCDS , Eric N. Prystowsky MD, FHRS , Sanjeev Saksena MBBS, MD, FHRS
{"title":"In Memoriam: Victor Parsonnet, MD, FHRS, a Heart Rhythm Society founder and pioneer in cardiac pacing and electrophysiology","authors":"David G. Benditt MD, FHRS, CCDS , Eric N. Prystowsky MD, FHRS , Sanjeev Saksena MBBS, MD, FHRS","doi":"10.1016/j.hrthm.2025.02.001","DOIUrl":"10.1016/j.hrthm.2025.02.001","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"22 4","pages":"Pages 1127-1128"},"PeriodicalIF":5.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart rhythmPub Date : 2025-03-28DOI: 10.1016/j.hrthm.2024.11.037
Sana M. Al-Khatib MD, MHS, FHRS
{"title":"A discourse on primary prevention implantable cardioverter-defibrillators for heart failure is understandable, but answers must be sought appropriately","authors":"Sana M. Al-Khatib MD, MHS, FHRS","doi":"10.1016/j.hrthm.2024.11.037","DOIUrl":"10.1016/j.hrthm.2024.11.037","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"22 4","pages":"Pages 1052-1054"},"PeriodicalIF":5.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart rhythmPub Date : 2025-03-28DOI: 10.1016/j.hrthm.2025.02.019
Wojciech Zareba MD, PhD
{"title":"MADIT II trial: A 2002 breakthrough in primary prevention of mortality with implantable cardioverter-defibrillator","authors":"Wojciech Zareba MD, PhD","doi":"10.1016/j.hrthm.2025.02.019","DOIUrl":"10.1016/j.hrthm.2025.02.019","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"22 4","pages":"Pages 882-883"},"PeriodicalIF":5.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart rhythmPub Date : 2025-03-28DOI: 10.1016/j.hrthm.2025.02.008
Ian H. Law MD, FHRS, Benjamin W. Hale MD, FHRS
{"title":"Problems and possibilities of pacing the Fontan population","authors":"Ian H. Law MD, FHRS, Benjamin W. Hale MD, FHRS","doi":"10.1016/j.hrthm.2025.02.008","DOIUrl":"10.1016/j.hrthm.2025.02.008","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"22 4","pages":"Pages 1123-1124"},"PeriodicalIF":5.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart rhythmPub Date : 2025-03-28DOI: 10.1016/j.hrthm.2025.01.038
Marina Cerrone MD
{"title":"Top stories on advancements in gene therapy for inherited arrhythmogenic diseases: From preclinical studies to initial results in patients","authors":"Marina Cerrone MD","doi":"10.1016/j.hrthm.2025.01.038","DOIUrl":"10.1016/j.hrthm.2025.01.038","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"22 4","pages":"Pages 1125-1126"},"PeriodicalIF":5.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart rhythmPub Date : 2025-03-28DOI: 10.1016/j.hrthm.2025.02.018
Dhanunjaya Lakkireddy MD, MBA, FHRS , Andrea Natale MD, FHRS
{"title":"Enhancing member value and protecting the electrophysiology profession—Heart Rhythm Advocates are here","authors":"Dhanunjaya Lakkireddy MD, MBA, FHRS , Andrea Natale MD, FHRS","doi":"10.1016/j.hrthm.2025.02.018","DOIUrl":"10.1016/j.hrthm.2025.02.018","url":null,"abstract":"","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":"22 4","pages":"Pages 880-881"},"PeriodicalIF":5.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart rhythmPub Date : 2025-03-25DOI: 10.1016/j.hrthm.2025.03.1977
Ioan Liuba, Arwa Younis, Paresh Vasandani, Jakub Sroubek, Koji Higuchi, Justin Lee, Walid Saliba, Alison Krywanczyk, Shady Nakhla, Mandeep Bhargava, Ayman Hussein, Mohamed Kanj, Samir Kapadia, Oussama Wazni, Pasquale Santangeli
{"title":"A Dedicated Radiofrequency Microcatheter Assembly For Trans-Right Atrial Appendage Pericardial Carbon Dioxide Insufflation To Facilitate Epicardial Access.","authors":"Ioan Liuba, Arwa Younis, Paresh Vasandani, Jakub Sroubek, Koji Higuchi, Justin Lee, Walid Saliba, Alison Krywanczyk, Shady Nakhla, Mandeep Bhargava, Ayman Hussein, Mohamed Kanj, Samir Kapadia, Oussama Wazni, Pasquale Santangeli","doi":"10.1016/j.hrthm.2025.03.1977","DOIUrl":"https://doi.org/10.1016/j.hrthm.2025.03.1977","url":null,"abstract":"<p><strong>Background: </strong>Trans-right atrial appendage (RAA) pericardial insufflation of CO<sub>2</sub> can improve safety of percutaneous epicardial access. Dedicated device solutions for safe, effective and standardized microperforation are needed.</p><p><strong>Objectives: </strong>We evaluated the efficacy and safety of a novel radiofrequency (RF)-powered microcatheter specifically designed to facilitate trans-RAA exit to the pericardial space.</p><p><strong>Methods: </strong>Four healthy swine underwent repeated RAA and left atrial appendage (LAA) perforations to access the pericardial space via a dedicated 1.8 Fr microcatheter with an RF tip. Perforations were obtained by delivering short bursts of RF energy (20-25 W, <1 second, \"cut\" mode). Animals were sacrificed immediately after the experiment and the hearts were assessed by gross pathology and histology.</p><p><strong>Results: </strong>A median number of 7 microperforations/animal (interquartile range, IQR: 7-9) were performed in the RAA and 3/animal (IQR: 2-3) in the LAA. In one animal, a postero-lateral RA perforation was also performed. All perforations and microcatheter advancements in the pericardial space were successful (<5 seconds). There was no evidence of pericardial effusion by intracardiac echocardiography and no hemodynamic changes with any of the perforations. On pathology, no pericardial effusion was noted and the atrial perforations could be identified as punctate red areas (0.5-1 mm) in 28/31 targeted RAA sites and 5/8 targeted LAA sites. Histology showed central full-thickness defects with associated acute thrombus formation and surrounded by a small rim of contraction bands necrosis.</p><p><strong>Conclusions: </strong>In this pre-clinical study, repeated trans-RAA/LAA perforations with pericardial space access were successfully obtained with a dedicated RF-tip 1.8 Fr microcatheter with no evidence of significant pericardial bleeding.</p>","PeriodicalId":12886,"journal":{"name":"Heart rhythm","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}