Hellenic journal of nuclear medicine最新文献_第10页

Combination of myocardial perfusion imaging, left ventricle function parameters and coronary artery calcium score in risk evaluation in patients with diabetes mellitus. 联合心肌灌注显像、左心室功能参数及冠状动脉钙化评分评价糖尿病患者的危险性。

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912510

Martin Havel, Milan Kaminek, Iva Metelkova, Lenka Henzlova, Libuse Quinn, Gabriela Havlova

{"title":"Combination of myocardial perfusion imaging, left ventricle function parameters and coronary artery calcium score in risk evaluation in patients with diabetes mellitus.","authors":"Martin Havel, Milan Kaminek, Iva Metelkova, Lenka Henzlova, Libuse Quinn, Gabriela Havlova","doi":"10.1967/s002449912510","DOIUrl":"https://doi.org/10.1967/s002449912510","url":null,"abstract":"Objective: Myocardial perfusion imaging (MPI) can be challenging in some cases of multi vessel involvement. Our aim was to examine specific group of patients with diabetes mellitus (DM), who did not have significant reversible ischaemia diagnosed on perfusion study itself, and asses additional value of functional parameters obtained from gated acquisition and added information from coronary artery calcium score (CACS).Subjects and methods: One hundred and seventy eight patients with a history of DM, with summed difference score (SDS)≤1, were included in the study. All patients underwent gated acquisition with recording of functional parameters and CACS evaluation. During the follow-up, cardiac events (CE) were recorded.Results: During the median follow-up of 20.3 months there were 23 CE encountered. Optimal cut-off value for CACS to predict CE was found at 1427, higher values were significantly related to CE (P<0.001). Low stress left ventricular ejection fraction (LVEF) <45% and induced stress LVEF drop for 5% were also more frequent in CE group (P=0.001, P=0.008). Multivariable Cox analysis revealed low stress LVEF (P=0.001, HR=4.48, 95%CI 1.79-11.22), stress induced LVEF drop (P=0.017, HR 3.13, 95%CI 1.22-8.01) and high CACS (P<0.001, HR 10.52, 95%CI 4.32-25.63) as significant predictors of CE.Conclusion: Low stress LVEF under 45%, post-stress LVEF drop for more than 5% and CACS more than or equal to 1427 are significant predictors of CE in patients with DM, who did not have reversible ischemia detected on MPI single photon emission computed tomography (SPECT).","PeriodicalId":12871,"journal":{"name":"Hellenic journal of nuclear medicine","volume":"25 3","pages":"227-234"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10799113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High grade glioma recurrence presenting as extensive tumor thrombus and simultaneous pulmonary metastasis revealed on ¹⁸F-FDG PET/CT. 18F-FDG PET/CT显示高度胶质瘤复发，表现为广泛的肿瘤血栓和同时的肺转移。

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912520

Hangyu Xie, Liu Xiao, Lin Li

引用次数: 0

Eosinophilic abscess of rib on ¹⁸F-FDG PET/CT: A mimic of bone tumor. 18F-FDG PET/CT示肋骨嗜酸性脓肿:模拟骨肿瘤。

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912519

Fanhui Yang, Lingzhi Cao, Fei Chen, Xiaohong Huang, Suping Li

引用次数: 0

Dosimetric approach to ¹³¹I ablation therapy for the differentiated thyroid cancer. 131I消融治疗分化型甲状腺癌的剂量学研究。

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912514

Fatma Arzu Görtan, Alptug Özer Yüksel, Nedim C M Gülaldı, Nazım Coşkun, Ceren D K Akça

{"title":"Dosimetric approach to 131I ablation therapy for the differentiated thyroid cancer.","authors":"Fatma Arzu Görtan, Alptug Özer Yüksel, Nedim C M Gülaldı, Nazım Coşkun, Ceren D K Akça","doi":"10.1967/s002449912514","DOIUrl":"https://doi.org/10.1967/s002449912514","url":null,"abstract":"Objective: The aim of this study is to compare the activity amounts used in the standard activity approach with the activity amounts calculated with the dosimetric method for the ablation of post-operative differentiated thyroid cancer residual tissue.Subjects and methods: Seventeen patients (mean age=47.5±8.4 years) were included in the study. Time-activity curves were created by measuring iodine-131 (131I) uptake values of residual tissue at 4th, 24th, 48th and 96th hours following oral administration of 131I. In a dosimetric approach, activity amounts exposing 300Gy to residual tissue were calculated using medicalinternal radiation dose (MIRD) formulation.Results: Dosimetric calculation could not be made in 3 patients because there was not enough radioactive iodine uptake (RAIU) at the neck to calculate the radioactive iodine treatment (RAIT) dose. The lowest and highest activity amounts determined by dosimetric calculations were 259MBq and 10860MBq, respectively. Dose amounts for the proposed treatment were decreased in 8 and increased in 6 patients compared to the standard activity approach. Cumulative activity (CA) and total cumulative activity (TCA) levels were found to be high in 1 patient who could not achieve adequate ablation.Conclusion: We recommend the dosimetric approach for ablation of residual postoperative thyroid tissue to find patients with high levels of CA and TCA levels to consider higher activity doses compared to risk stratification assessment.","PeriodicalId":12871,"journal":{"name":"Hellenic journal of nuclear medicine","volume":"25 3","pages":"260-268"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10799573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¹⁸F-FDG PET/CT and clinicopathological characteristics of neurolymphomatosis in lymphoma patients. 18F-FDG PET/CT与淋巴瘤患者神经淋巴瘤病的临床病理特征

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912517

Xiaoyue Tan, Xiaolin Sun, Hui Yuan, Li He, Chongyang Ding, Lei Jiang

{"title":"18F-FDG PET/CT and clinicopathological characteristics of neurolymphomatosis in lymphoma patients.","authors":"Xiaoyue Tan, Xiaolin Sun, Hui Yuan, Li He, Chongyang Ding, Lei Jiang","doi":"10.1967/s002449912517","DOIUrl":"https://doi.org/10.1967/s002449912517","url":null,"abstract":"Objective: Neurolymphomatosis (NL) is a rare but serious manifestation defined as invasion of peripheral nervous system by malignant lymphocytes. Thus, this study investigated fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) and clinicopathological characteristics of NL in lymphoma patients.Subjects and methods: Clinicopathological and 18F-FDG PET/CT findings and treatment regimens were retrospectively investigated in 20 lymphoma patients with NL, and analyzed their correlation with progression-free survival (PFS) and overall survival (OS).Results: These 20 lymphoma patients (11 males, 9 females; median age, 49 years) included 10 primary and 10 secondary NL patients. Non-Hodgkin's lymphoma (NHL) was noted in 19 patients, B-cell NHL was associated with 18 cases, and diffuse large B-cell lymphoma was the most common. Notably, 18 patients were aggressive lymphoma while 2 were indolent lymphoma. The affected neural structures included nerve roots (n=17), peripheral nerves (n=3), cranial nerves (n=3), and neural plexus (n=2). Fluorine-18-FDG was avid in all cases, and the median maximum standardized uptake value (SUVmax) of neural and all lesions was 12.2 (range, 3.3-25.6) and 15.0 (range, 4.4-34.2), respectively. The median PFS and OS of all patients were 9.3 and 14.3 months. The 12-month OS rate of 18 patients with aggressive lymphoma receiving intrathecal chemotherapy/autologous stem cell transplants (IT chem/ASCT) was significantly higher than who did not (64.8% vs 15.9%).Conclusion: The majority of NL occurred in patients with aggressive lymphoma, of which B-cell NHL were the predominant subtypes. Fluorine-18-FDG PET/CT imaging of NL was mainly characterized by intense glucose accumulation alongside peripheral nerves, and IT chem/ASCT was suggested to improve the outcomes of NL.","PeriodicalId":12871,"journal":{"name":"Hellenic journal of nuclear medicine","volume":"25 3","pages":"285-296"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10799571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of quantitative bone SPECT/CT for bone metastasis diagnosis. 定量骨SPECT/CT诊断骨转移的有效性。

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912513

Takashi Ikeda, Kazuhiro Kitajima, Tatsuya Tsuchitani, Yoshiyuki Takahashi, Yasuhiko Hama, Noriko Kotura

{"title":"Effectiveness of quantitative bone SPECT/CT for bone metastasis diagnosis.","authors":"Takashi Ikeda, Kazuhiro Kitajima, Tatsuya Tsuchitani, Yoshiyuki Takahashi, Yasuhiko Hama, Noriko Kotura","doi":"10.1967/s002449912513","DOIUrl":"https://doi.org/10.1967/s002449912513","url":null,"abstract":"Objective: This study was conducted to investigate the utility of standardized uptake value (SUV) derived from bone single photon emission tomography/computed tomography (SPECT/CT) for diagnosing bone metastasis.Subjects and methods: One hundred forty-seven patients with malignant cancer (breast or prostate cancer), joint disorders, primary skeletal disease, or cartilaginous bone neoplasms who underwent skeletal quantitative SPECT/CT were retrospectively investigated. Acquired data were classified as normal fourth lumbar vertebra, skeletal degenerative changes, or bone metastasis. Receiver operating characteristic (ROC) curves were used to determine the optimum cut-off value for SUVmax to distinguish among these diagnoses.Results: Mean SUVmax values for the normal L4 bone (n=101), skeletal degenerative changes (n=47) and bone metastasis (n=64) groups were 4.47±1.66 (range 1.01-11.25), 6.99±2.58 (2.21-14.6), and 25.4±15.7 (3.88-98.87), respectively. Compared to the other two groups, SUVmax for the bone metastasis group was significantly higher (P<0.001). In the normal bone group, sensitivity, specificity and accuracy for discriminating bone metastasis were 96.3%, 95.1%, and 95.7% respectively, with a best SUVmax cut-off value of 7.40. For the skeletal degenerative changes group sensitivity, specificity and accuracy were 87.5%, 93.6%, and 90.4% respectively, with a best SUVmax cut-off value of 11.26.Conclusion: Quantitative bone SPECT/CT may be useful for bone metastasis diagnosis.","PeriodicalId":12871,"journal":{"name":"Hellenic journal of nuclear medicine","volume":"25 3","pages":"253-259"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10799574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The role of basal metabolic and volumetric ¹⁸F-FDG PET/CT parameters and their changes in predicting pathological complete response in breast cancer patients receiving neoadjuvant chemotherapy. 基础代谢和体积18F-FDG PET/CT参数及其变化在预测乳腺癌新辅助化疗患者病理完全缓解中的作用

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912511

Ferat Kepenek, Hüseyin Karaoğlan, Canan Can, Halil Kömek, İhsan Kaplan, Hülya Etem, Senar Ebinç, Şeyhmus Kavak, Cihan Gündoğan

{"title":"The role of basal metabolic and volumetric 18F-FDG PET/CT parameters and their changes in predicting pathological complete response in breast cancer patients receiving neoadjuvant chemotherapy.","authors":"Ferat Kepenek, Hüseyin Karaoğlan, Canan Can, Halil Kömek, İhsan Kaplan, Hülya Etem, Senar Ebinç, Şeyhmus Kavak, Cihan Gündoğan","doi":"10.1967/s002449912511","DOIUrl":"https://doi.org/10.1967/s002449912511","url":null,"abstract":"Objective: The aim of this study is to investigate the roles of pre- and post- treatment quantitative fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) parameters including maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) and their rate of change in predicting pathological complete response (pCR) in patients with local and locally advanced invasive breast cancer receiving neoadjuvant chemotherapy (NAC).Subjects and methods: Ninety-eight patients who received NAC after being diagnosed with local and locally advanced invasive breast cancer between January 2017 and September 2021 were retrospectively included in our study. Molecular subtypes of all patients were determined. Maximum SUV, MTV, TLG, percent change in SUVmax (ΔSUVmax), ΔMTV, and ΔTLG obtained from PET/CT scans performed before and after NAC were calculated. The cut-off, AUC, sensitivity, and specificity values of these parameters in predicting pCR were calculated using receiver operating characteristic (ROC) curves.Results: ΔTMTV (cut-off 94.01%, AUC: 0.846), ΔTTLG (cut-off 97.36%, AUC: 0.870), B2MTV (cut-off<1.75, AUC: 0.764), B2TLG (cut-off<2.11, AUC: 0.764), B2SUVmax (cut-off<1.58, AUC: 0.767), ΔBMTV (cut-off 93.67%, AUC: 0.851), ΔBTLG (cut-off 97.22%, AUC: 0.870), ΔBSUVmax (cut-off 84.99%, AUC: 0.846) calculated using ROC curves were found to significantly predict pCR with high sensitivity and specificity.Conclusion: We concluded that metabolic and volumetric PET/CT parameters, the rates of their change, and metabolic response during NAC may be important variables in predicting pCR in patients with breast cancer.","PeriodicalId":12871,"journal":{"name":"Hellenic journal of nuclear medicine","volume":"25 3","pages":"235-246"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10799115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusually seen pattern of ^99mTc-DPD soft tissue uptake in a patient with AL amyloidosis. Is it an amyloid type indicator in specific cases? AL淀粉样变患者99mTc-DPD软组织摄取异常。在特定情况下它是淀粉样蛋白类型的指示物吗?

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912526

Argyrios Doumas, Iakovos Armenis, Vasileios Chatzoglou, Spyridoula Kitziri, Emmanouil Papanastasiou, Maria Koutelou

引用次数: 0

Hepatic brucellosis detected by ¹⁸F-FDG PET/CT. 18F-FDG PET/CT检测肝布鲁氏菌病。

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912518

Mehraban Jaromi Nariman, Johannes Andel, Jarub Salaheddin, Mario Bachmayr, Robert Pichler

引用次数: 0

¹⁸F-FDG PET/CT imaging of multiple intrahepatic Epstein-Barr virus-associated smooth muscle tumors in a pediatric patient after heart transplantation. 1例儿童心脏移植术后肝内多个eb病毒相关平滑肌肿瘤的18F-FDG PET/CT成像

IF 1.5 4区医学

Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI: 10.1967/s002449912521

Hui Yuan, Baozhen Zeng, Li He, Xiaoyue Tan, Lei Jiang

引用次数: 1