Herz最新文献 - Book学术

Transcatheter mitral valve replacement. 经导管二尖瓣置换术

IF 0.9 4区医学

Herz Pub Date : 2026-05-05 DOI: 10.1007/s00059-026-05377-7

Tobias Friedrich Ruf, Theresa Ann-Marie Gößler, Philipp Lurz

引用次数: 0

Research hotspots and emerging trends of exosomes in myocardial infarction: a bibliometric-based visual analysis. 心肌梗死中外泌体的研究热点和新趋势：基于文献计量学的可视化分析。

IF 0.9 4区医学

Herz Pub Date : 2026-04-28 DOI: 10.1007/s00059-026-05379-5

Runfang Deng, Weiju Liao, Lingling Wu, Dongyi Huang, Tingting Huang, Xingzhen Huang

{"title":"Research hotspots and emerging trends of exosomes in myocardial infarction: a bibliometric-based visual analysis.","authors":"Runfang Deng, Weiju Liao, Lingling Wu, Dongyi Huang, Tingting Huang, Xingzhen Huang","doi":"10.1007/s00059-026-05379-5","DOIUrl":"https://doi.org/10.1007/s00059-026-05379-5","url":null,"abstract":"Objective: The aim of this study was to summarize the current research status and application of exosomes in the treatment of myocardial infarction (MI) through bibliometric analysis and to provide insights and suggestions for future research.Methods: We searched the Web of Science Core Collection database for publications on exosome-based treatments for MI from 2000 to 2023. Bibliometric and visualization analyses were conducted using VOSviewer and CiteSpace.Results: A total of 6138 authors from 96 institutions in 65 countries and regions published 1062 articles in 358 academic journals. The majority of publications were from China and the United States. Nanjing Medical University and Soochow University are the most active institutions. Cheng was the author with the highest number of publications, while Barile was the most co-cited. The International Journal of Molecular Sciences had the highest publication output while Circulation Research was the most cited journal. Current research focuses on areas likely to be future hot topics, such as \"repair,\" \"mesenchymal stem cells,\" \"progenitor cells,\" \"endothelial cells,\" \"expression,\" \"bone marrow,\" \"apoptosis,\" \"drug delivery,\" \"inflammation,\" and \"cells.\" Future research directions include exploring the mechanisms of exosomes from various cellular sources for MI treatment, investigating different drug delivery modes, developing post-MI therapeutic strategies, regulating apoptotic protein expression, and emphasizing the roles of different stem cells and molecules in exosome studies for MI treatment.Conclusion: In the field of MI, exosomes represent an excellent drug delivery system. This analysis offers valuable insights into research hotspots and cutting-edge directions for scholars in related fields.","PeriodicalId":12863,"journal":{"name":"Herz","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147769880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced interatrial block independently predicts appropriate and inappropriate ICD therapies in hypertrophic cardiomyopathy. 晚期房间传导阻滞独立预测肥厚性心肌病适当和不适当的ICD治疗。

IF 0.9 4区医学

Herz Pub Date : 2026-04-28 DOI: 10.1007/s00059-026-05378-6

Nizamettin Selçuk Yelgeç, Can Baba Arın, Ayşegül Aygün, Musa Çağrı Bolca, Kadir Gürkan

{"title":"Advanced interatrial block independently predicts appropriate and inappropriate ICD therapies in hypertrophic cardiomyopathy.","authors":"Nizamettin Selçuk Yelgeç, Can Baba Arın, Ayşegül Aygün, Musa Çağrı Bolca, Kadir Gürkan","doi":"10.1007/s00059-026-05378-6","DOIUrl":"https://doi.org/10.1007/s00059-026-05378-6","url":null,"abstract":"Background: Implantable cardioverter-defibrillators (ICDs) reduce the risk of sudden cardiac death in hypertrophic cardiomyopathy (HCM); however, both appropriate and inappropriate shocks carry important clinical implications. Advanced interatrial block (IAB) is an electrocardiographic marker of atrial conduction disease, but its prognostic impact on ICD shocks in HCM remains unclear.Methods: We retrospectively analyzed consecutive patients with HCM who underwent ICD implantation between 2014 and 2024. Advanced IAB was defined as a P-wave duration of ≥ 120 ms with biphasic morphology in the inferior leads. Appropriate ICD shocks were delivered for sustained ventricular tachycardia or ventricular fibrillation, whereas inappropriate shocks resulted from supraventricular arrhythmias or device-related causes. Time to first ICD shock was assessed using Kaplan-Meier analysis and multivariable Cox proportional hazards regression.Results: A total of 184 patients were included (median follow-up: 68.5 months). Patients with advanced IAB exhibited significantly lower shock-free survival for both appropriate and inappropriate ICD shocks. Advanced IAB independently predicted appropriate ICD shocks (hazard ratio [HR]: 6.03, 95% confidence interval [CI]: 2.68-13.57; p < 0.001), together with non-sustained ventricular tachycardia (HR: 7.98; p < 0.001). Advanced IAB was also an independent predictor of inappropriate ICD shocks (HR: 3.50, 95% CI: 1.78-6.86; p < 0.001), along with left atrial diameter, atrial fibrillation, and age.Conclusion: Advanced interatrial block is independently associated with an increased risk of both appropriate and inappropriate ICD shocks in patients with HCM. This simple ECG marker may enhance risk stratification and help optimize ICD follow-up and programming strategies.","PeriodicalId":12863,"journal":{"name":"Herz","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147769912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cardiovascular pharmacotherapy in the era of RNA-based precision medicine]. 【rna精准医学时代的心血管药物治疗】。

IF 0.9 4区医学

Herz Pub Date : 2026-04-07 DOI: 10.1007/s00059-026-05375-9

Anselm A Derda, Anna Hohneck

引用次数: 0

Contemporary insights and evolving clinical pathways in transcatheter tricuspid valve replacement. 经导管三尖瓣置换术的当代见解和不断发展的临床途径。

IF 0.9 4区医学

Herz Pub Date : 2026-03-03 DOI: 10.1007/s00059-026-05371-z

J G da Rocha E Silva, L Stolz, H Kempton, L T Weckbach, T J Stocker, P Doldi, J Novotny, M Näbauer, Jörg Hausleiter

引用次数: 0

[Response to the letter to the editor from K. Toussaint]. [对K. Toussaint给编辑的信的回应]。

IF 0.9 4区医学

Herz Pub Date : 2026-03-01 Epub Date: 2026-02-11 DOI: 10.1007/s00059-026-05368-8

Anna Hohneck, Oliver Weingärtner

引用次数: 0

[Artificial intelligence in risk stratification of acute coronary syndrome : Future vision or already reality?] 人工智能在急性冠状动脉综合征风险分层中的应用：未来愿景还是现实？］

IF 0.9 4区医学

Herz Pub Date : 2026-03-01 Epub Date: 2026-01-14 DOI: 10.1007/s00059-025-05360-8

A Büscher, L Plagwitz, J Blaschke, D Heider, L Eckardt

{"title":"[Artificial intelligence in risk stratification of acute coronary syndrome : Future vision or already reality?]","authors":"A Büscher, L Plagwitz, J Blaschke, D Heider, L Eckardt","doi":"10.1007/s00059-025-05360-8","DOIUrl":"10.1007/s00059-025-05360-8","url":null,"abstract":"Artificial intelligence (AI) in cardiology has evolved from rule-based expert systems to data-driven, learning models that can support diagnostic and therapeutic decision-making in acute coronary syndrome (ACS). At their core, these are statistical prediction models that infer conditional probabilities for clinical events from data and are therefore, in principle, ideally suited for risk-based decision making. This review article focuses on risk stratification in ACS, with particular emphasis on the detection of type 1 or occlusive myocardial infarction (MI). Models based on clinical variables and high-sensitivity troponin measurements use continuous troponin values in combination with patient characteristics to estimate individual probabilities of MI instead of relying on fixed troponin thresholds. In retrospective studies, they reduce the \"observe zone\", enable faster and safer rule-out decisions, and have the potential to relieve pressure on emergency departments. However, they remain dependent on laboratory assays and currently lack prospective evidence of improvements in patient relevant outcomes. Electrocardiogram (ECG)-based approaches promise greater clinical impact: classical machine learning (ML) on preselected ECG features already yields interpretable models that quantify ischemic patterns and can detect occlusive MI even in the absence of ST-segment elevation. Deep learning models applied directly to raw ECG signals additionally exploit subtle spatiotemporal changes and have outperformed conventional ECG interpretation in early studies. Prospective data on the detection of ST segment elevation myocardial infarction (STEMI) indicate that this can shorten the time to reperfusion.","PeriodicalId":12863,"journal":{"name":"Herz","volume":" ","pages":"92-99"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Telemedicine in heart failure : Evidence, benefits and future perspectives]. [心力衰竭的远程医疗：证据、益处和未来展望]。

IF 0.9 4区医学

Herz Pub Date : 2026-03-01 Epub Date: 2026-01-22 DOI: 10.1007/s00059-026-05364-y

Simon Glück, Oliver Przibille, Friedrich Köhler, Ralph Bosch, Eimo Martens

{"title":"[Telemedicine in heart failure : Evidence, benefits and future perspectives].","authors":"Simon Glück, Oliver Przibille, Friedrich Köhler, Ralph Bosch, Eimo Martens","doi":"10.1007/s00059-026-05364-y","DOIUrl":"10.1007/s00059-026-05364-y","url":null,"abstract":"In recent years telemonitoring for heart failure (TmHi) has transitioned from project-based pilot applications to a structured and fully reimbursed component of routine outpatient care in Germany. This development is supported by robust evidence from randomized controlled trials and meta-analyses demonstrating consistent reductions in mortality and hospitalizations, improved treatment adherence and enhanced continuity of care. Both noninvasive and implant-based monitoring strategies enable early detection of pathophysiological deterioration and facilitate proactive therapeutic adjustments through telemedicine centers (TMZ) in close collaboration with primary physicians. The implementation of TmHi in Germany relies on clear legal, technical and organizational standards, although current practice across centers remains heterogeneous and reveals potential for improvement in workflow standardization, interoperability, staffing and reimbursement management. In addition to the proven clinical benefits, in the context of the demographic changes TmHi is gaining in importance economically and in the healthcare system. Telemonitoring is thus poised to evolve from a specialized adjunct service into a cornerstone of predictive, digitally integrated care of heart failure.","PeriodicalId":12863,"journal":{"name":"Herz","volume":" ","pages":"108-115"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Same-day discharge in electrophysiology : Overview for the practice]. 【电生理学当日出院：实践综述】。

IF 0.9 4区医学

Herz Pub Date : 2026-03-01 Epub Date: 2026-01-29 DOI: 10.1007/s00059-026-05366-w

Julia Vogler, Joachim R Ehrlich, Henning Jansen, Oliver Przibille, Roland R Tilz, Christoph Stellbrink, Arian Sultan, Stephan Willems

引用次数: 0

[Commentary on "ESC Guidelines Update 2025 on Dyslipidemia: New Recommendations for Practice"]. [对“ESC指南更新2025：新的实践建议”的评论]。

IF 0.9 4区医学

Herz Pub Date : 2026-03-01 Epub Date: 2026-02-11 DOI: 10.1007/s00059-025-05363-5

Kai Toussaint

引用次数: 0