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Folate-driven changes in snoRNA function: a novel epigenetic-ribosomal axis in hepatocellular carcinoma. 叶酸驱动的snoRNA功能改变：肝细胞癌中一种新的表观遗传-核糖体轴。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-23 DOI: 10.1186/s41065-026-00666-x
Xinxin Song, Deyu Kong, Yongjiao Zi, Xu Wang, Juan Ni
{"title":"Folate-driven changes in snoRNA function: a novel epigenetic-ribosomal axis in hepatocellular carcinoma.","authors":"Xinxin Song, Deyu Kong, Yongjiao Zi, Xu Wang, Juan Ni","doi":"10.1186/s41065-026-00666-x","DOIUrl":"10.1186/s41065-026-00666-x","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancer-based gene therapy: a new path for precision medicine. 基于增强子的基因治疗：精准医学的新途径。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-21 DOI: 10.1186/s41065-026-00655-0
Hany E Marei
{"title":"Enhancer-based gene therapy: a new path for precision medicine.","authors":"Hany E Marei","doi":"10.1186/s41065-026-00655-0","DOIUrl":"10.1186/s41065-026-00655-0","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147491121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification and external validation of a prognostic signature based on myeloid-derived suppressor cell-related lncRNAs for hepatocellular carcinoma. 基于髓源性抑制细胞相关lncrna的肝细胞癌预后特征的鉴定和外部验证
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-19 DOI: 10.1186/s41065-026-00664-z
Tong Mu, Shunyao Zhang, Yun Zhong, Zijian Zhou, Lei Xie, Yajie Zhou, Wenxiong Zhang, Liang Zhai
{"title":"Identification and external validation of a prognostic signature based on myeloid-derived suppressor cell-related lncRNAs for hepatocellular carcinoma.","authors":"Tong Mu, Shunyao Zhang, Yun Zhong, Zijian Zhou, Lei Xie, Yajie Zhou, Wenxiong Zhang, Liang Zhai","doi":"10.1186/s41065-026-00664-z","DOIUrl":"10.1186/s41065-026-00664-z","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13123200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147485745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cuproptosis of endothelial cells in a hypoxic environment: from molecular classification to PMAIP1-targeted intervention. 缺氧环境下内皮细胞铜变：从分子分类到pmaip1靶向干预
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-19 DOI: 10.1186/s41065-026-00667-w
Jie Wang, Xueying Chen, Huabin Wang, Wenjing Feng, Nan Lin, Xueyun Ren, Manman Wang, Lijun Gan
{"title":"Cuproptosis of endothelial cells in a hypoxic environment: from molecular classification to PMAIP1-targeted intervention.","authors":"Jie Wang, Xueying Chen, Huabin Wang, Wenjing Feng, Nan Lin, Xueyun Ren, Manman Wang, Lijun Gan","doi":"10.1186/s41065-026-00667-w","DOIUrl":"10.1186/s41065-026-00667-w","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13123213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147485773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A prognostic model for gastric cancer based on histamine-associated prognostic genes. 基于组胺相关预后基因的胃癌预后模型。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-11 DOI: 10.1186/s41065-026-00659-w
Yan Zhang, Na Liu, Xiao Dong, Yu Li, Jinrui Geng, Yonghong Li
{"title":"A prognostic model for gastric cancer based on histamine-associated prognostic genes.","authors":"Yan Zhang, Na Liu, Xiao Dong, Yu Li, Jinrui Geng, Yonghong Li","doi":"10.1186/s41065-026-00659-w","DOIUrl":"10.1186/s41065-026-00659-w","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13093977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147432591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the role of lncRNA SNHG14 in early diagnosis and prognosis of acute pancreatitis: a bioinformatics exploration. 探讨lncRNA SNHG14在急性胰腺炎早期诊断和预后中的作用：生物信息学探索。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-11 DOI: 10.1186/s41065-026-00656-z
Qilin Zhu, Bin Liang, Dongqin Shen, Wei Chen, Hanqing Liao
{"title":"Investigating the role of lncRNA SNHG14 in early diagnosis and prognosis of acute pancreatitis: a bioinformatics exploration.","authors":"Qilin Zhu, Bin Liang, Dongqin Shen, Wei Chen, Hanqing Liao","doi":"10.1186/s41065-026-00656-z","DOIUrl":"10.1186/s41065-026-00656-z","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13088405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147432549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardamonin ameliorates neuroinflammation in Parkinson's disease by regulating NF-κB signaling. 小豆蔻素通过调节NF-κB信号通路改善帕金森病的神经炎症。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-09 DOI: 10.1186/s41065-026-00660-3
Yezi Xia, Yinwei Zhang, Ying Li, Xiaojing Li, Yaling Wu, Qi Yao
{"title":"Cardamonin ameliorates neuroinflammation in Parkinson's disease by regulating NF-κB signaling.","authors":"Yezi Xia, Yinwei Zhang, Ying Li, Xiaojing Li, Yaling Wu, Qi Yao","doi":"10.1186/s41065-026-00660-3","DOIUrl":"10.1186/s41065-026-00660-3","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrated bioinformatics analysis and experimental validation reveal Pevonedistat as a promising therapeutic agent modulating the CRL4-DTL-p21/p53 axis in nasopharyngeal carcinoma. 综合生物信息学分析和实验验证表明，佩onedistat是一种有前景的治疗鼻咽癌的药物，可调节CRL4-DTL-p21/p53轴。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-07 DOI: 10.1186/s41065-026-00661-2
Cong-Chao Jia, Zhen-Yi Li, Wei-Hua Jia, Cheng-Tao Jiang
{"title":"Integrated bioinformatics analysis and experimental validation reveal Pevonedistat as a promising therapeutic agent modulating the CRL4-DTL-p21/p53 axis in nasopharyngeal carcinoma.","authors":"Cong-Chao Jia, Zhen-Yi Li, Wei-Hua Jia, Cheng-Tao Jiang","doi":"10.1186/s41065-026-00661-2","DOIUrl":"10.1186/s41065-026-00661-2","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13081564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perillaldehyde inhibits oxidative stress, NLRP3-mediated inflammation and fibrosis in diabetic nephropathy through regulating HMOX1. 紫苏醛通过调节HMOX1抑制糖尿病肾病的氧化应激、nlrp3介导的炎症和纤维化。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-06 DOI: 10.1186/s41065-026-00657-y
Wen Hao, Chunhua Liu, Jing Feng, Zhanliang Ren
{"title":"Perillaldehyde inhibits oxidative stress, NLRP3-mediated inflammation and fibrosis in diabetic nephropathy through regulating HMOX1.","authors":"Wen Hao, Chunhua Liu, Jing Feng, Zhanliang Ren","doi":"10.1186/s41065-026-00657-y","DOIUrl":"10.1186/s41065-026-00657-y","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147369518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
miR-3913-3p promoted the progression of lung adenocarcinoma by regulating STX3 expression. miR-3913-3p通过调节STX3的表达促进肺腺癌的进展。
IF 2.5 3区 生物学
Hereditas Pub Date : 2026-03-04 DOI: 10.1186/s41065-026-00654-1
Yu Wang, Lin Shen, Ruijie Cao, Hao Xu, Zhong Guo, Yuxing Chen, Dan Wang
{"title":"miR-3913-3p promoted the progression of lung adenocarcinoma by regulating STX3 expression.","authors":"Yu Wang, Lin Shen, Ruijie Cao, Hao Xu, Zhong Guo, Yuxing Chen, Dan Wang","doi":"10.1186/s41065-026-00654-1","DOIUrl":"10.1186/s41065-026-00654-1","url":null,"abstract":"","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13067435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147348252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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