Heart International最新文献_第8页

Pulmonary Regurgitation - Results from the Harmony™ Transcatheter Pulmonary Valve Trial. 肺返流——Harmony™经导管肺动脉瓣试验结果

IF 0.2

Heart International Pub Date : 2020-10-20 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.2.67

John Cheatham

引用次数: 1

Cardiovascular Effects of COVID-19 - What Do We Know and Where Should We Go? 新冠肺炎对心血管的影响-我们知道什么？我们应该去哪里？

IF 0.2

Heart International Pub Date : 2020-08-18 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.16

Matthew Ryan, Ozan Demir, Kevin O'Gallagher, Divaka Perera

引用次数: 4

Is There Still a Place for Revascularisation in the Management of Stable Coronary Artery Disease Following the ISCHEMIA Trial? ISCHEMIA 试验后，血管重建术在稳定型冠状动脉疾病的治疗中还有用武之地吗？

IF 1.9

Heart International Pub Date : 2020-08-08 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.13

Andre Briosa E Gala, Nick Curzen

引用次数: 0

The Coronary Sinus Reducer - Clinical Evidence and New Perspectives On An Emerging Tool in the Treatment of Refractory Angina. 冠状窦减速器-治疗难治性心绞痛的新工具的临床证据和新观点。

IF 0.2

Heart International Pub Date : 2020-08-04 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.29

Carlo Zivelonghi, Stefan Verheye

引用次数: 2

Ratio of Serum Aspartate to Alanine Aminotransferase as a Marker of Isolated Coronary Artery Ectasia and its Severity. 血清天冬氨酸/丙氨酸转氨酶比值作为离体冠状动脉扩张及其严重程度的标志。

IF 0.2

Heart International Pub Date : 2020-07-31 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.43

Danesh Soltani, Samira Jafari, Haleh Ashraf, Amir Sobh-Rakhshankhah, Zahra Kolahchi, Farzad Masoudkabir, Mohammad Ali Boroumand, Ali Vasheghani-Farahani

{"title":"Ratio of Serum Aspartate to Alanine Aminotransferase as a Marker of Isolated Coronary Artery Ectasia and its Severity.","authors":"Danesh Soltani, Samira Jafari, Haleh Ashraf, Amir Sobh-Rakhshankhah, Zahra Kolahchi, Farzad Masoudkabir, Mohammad Ali Boroumand, Ali Vasheghani-Farahani","doi":"10.17925/HI.2020.14.1.43","DOIUrl":"https://doi.org/10.17925/HI.2020.14.1.43","url":null,"abstract":"Background: Several studies have reported an association between elevated liver enzymes and increased risks for developing inflammatory diseases. The aim of our study was to examine how serum liver transaminases, as inexpensive and routinely measured markers, and the De Ritis ratio are associated with the presence of coronary artery ectasia (CAE) and its severity.Methods: Participants were recruited from patients admitted to Tehran Heart Center for diagnostic coronary angiography due to suspected myocardial ischaemia. These participants also underwent concurrent laboratory routine biochemical and liver enzyme tests.Results: A total of 104 participants were included; 59 had CAE and 45 were controls without coronary artery disease (CAD). The CAE group was split into a further two subgroups: those with isolated CAE (n=27) and those with CAD and coexisting CAE (n=32). In the adjusted multivariate analysis, a lower ratio of aspartate aminotransferase to ALT (AST/ALT) was, uniquely among the variables, a statistically significant marker for isolated CAE. In the CAD + CAE group, the AST/ALT ratio was not significant after adjustments for the confounding factors. The multivariate linear regression for the Markis score showed that the AST/ALT ratio was inversely associated with the severity of CAE.Conclusions: We conclude that the AST/ALT ratio and, to some extent, ALT independently of other inflammatory factors, can be associated with the presence and severity of isolated CAE.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"43-48"},"PeriodicalIF":0.2,"publicationDate":"2020-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524754/pdf/heart-int-14-43.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent Myocardial Ischaemia due to Anaemia in a Patient with Coeliac Disease - A Case Report. 腹腔疾病患者贫血致持续性心肌缺血1例报告

IF 0.2

Heart International Pub Date : 2020-07-16 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.49

Aleksandra Gąsecka, Karolina Kruk, Adam Przybyłkowski, Tomasz Mazurek, Janusz Kochman

{"title":"Persistent Myocardial Ischaemia due to Anaemia in a Patient with Coeliac Disease - A Case Report.","authors":"Aleksandra Gąsecka, Karolina Kruk, Adam Przybyłkowski, Tomasz Mazurek, Janusz Kochman","doi":"10.17925/HI.2020.14.1.49","DOIUrl":"https://doi.org/10.17925/HI.2020.14.1.49","url":null,"abstract":"Introduction: Coeliac disease (CD) is a systemic disease of inappropriate immune response to gluten, and is associated with 10% increased risk of cardiovascular disease. Here we present a case of a young patient with persistent myocardial ischaemia due to iron-deficiency anaemia despite oral iron supplementation, who was eventually diagnosed with CD.Case report: A 36-year-old man was admitted to the cardiology department due to ST-elevation myocardial infarction of the inferior wall. Emergency coronary angiography showed occlusion of the right coronary artery and intermediate-diameter lesions in other arteries. Primary percutaneous coronary intervention with stent implantation to the right coronary artery was performed. Despite the successful intervention, the patient presented with recurrent chest pain, persistent tachycardia up to 120 beats per minute and syncope. Coronary angiography was repeated and the intermediate-diameter lesions were proved insignificant. Laboratory tests revealed microcytic anaemia with haemoglobin level of 6.5 g/dL, despite oral iron supplementation in the pre-hospital period. An emergency gastroscopy with duodenoscopy revealed flat duodenal mucosa. The duodenal biopsy confirmed the diagnosis of CD. Strict gluten-free diet and further iron supplementation were recommended. Two months later the patient presented with no recurrent chest pain and normal haemoglobin concentration.Conclusions: Diagnosis of CD with atypical presentation can be difficult. Iron-deficiency anaemia refractory to oral iron supplementation should always raise the suspicion of CD, even without typical gastrointestinal manifestation.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"49-52"},"PeriodicalIF":0.2,"publicationDate":"2020-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524602/pdf/heart-int-14-49.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clopidogrel-induced Pill Oesophagitis. 氯吡格雷引起的食道炎。

IF 0.2

Heart International Pub Date : 2020-07-14 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.56

James C Blankenship, Matthew J Shellenberger

引用次数: 1

Andexanet Alfa and its Clinical Application. Andexanet Alfa 及其临床应用。

IF 1.9

Heart International Pub Date : 2020-06-19 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.20

Fauve A Noordergraaf, Marco Alings

{"title":"Andexanet Alfa and its Clinical Application.","authors":"Fauve A Noordergraaf, Marco Alings","doi":"10.17925/HI.2020.14.1.20","DOIUrl":"10.17925/HI.2020.14.1.20","url":null,"abstract":"Factor Xa (FXa) inhibitors are widely used for stroke prevention in patients with nonvalvular atrial fibrillation, and for the treatment and prevention of deep venous thrombosis and pulmonary embolism. Compared with warfarin, individual FXa inhibitors are associated with a lower risk of major bleeding. Nevertheless, bleeding remains a feared complication of any anticoagulant therapy. Despite their demonstrated safety, implementation of FXa inhibitors in clinical practice may have been limited by the lack of a specific antidote. Recently, however, the United States Food and Drug Administration and the European Medicines Agency approved andexanet alfa for reversal of anticoagulation in patients treated with rivaroxaban or apixaban who have life-threatening or uncontrolled bleeding. This review will discuss andexanet alfa's mode of action, indication for use and efficacy, with a focus on its appropriate use in clinical practice. Unnecessary usage should be prevented as this may compromise patient safety. Assessment of potentially suitable patients by a multidisciplinary team, use according to the institutional protocol and central storage, all contribute to proper use of andexanet alfa. A practical tool to direct appropriate use of andexanet alfa is proposed.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"20-23"},"PeriodicalIF":1.9,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524750/pdf/heart-int-14-20.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Contemporary Drug-eluting Coronary Stents - Is Any Stent Better than the Others? 当代药物洗脱冠状动脉支架的比较——是否有一种支架比其他支架更好?

IF 0.2

Heart International Pub Date : 2020-06-18 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.34

William Parker, Javaid Iqbal

{"title":"Comparison of Contemporary Drug-eluting Coronary Stents - Is Any Stent Better than the Others?","authors":"William Parker, Javaid Iqbal","doi":"10.17925/HI.2020.14.1.34","DOIUrl":"https://doi.org/10.17925/HI.2020.14.1.34","url":null,"abstract":"Percutaneous coronary intervention (PCI) with implantation of a metallic drug-eluting stent (DES) is the mainstay of treatment in patients with significant coronary artery disease or acute coronary syndromes. DESs comprise a metallic platform and an anti-proliferative drug, usually released from a polymer coating. A wide range of DESs, differing in platform, polymer or drug, are currently available for clinical use. Although there are significant differences in the physical, biological and pharmacological properties of contemporary DESs, it remains unclear whether these impact meaningfully on clinical outcomes for patients undergoing PCI. Numerous randomised clinical trials have compared DESs in recent years, but these trials are typically designed to show non-inferiority, rather than superiority. Data from meta-analyses have helped to study this in larger populations, but have limitations. Improvement in stent design continues and ongoing work is exploring the effects of new innovations as well as gathering further data on existing devices. This review explores the development, properties and clinical efficacy of current-generation DESs, comparing different types where possible, whilst identifying areas of further work.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"34-42"},"PeriodicalIF":0.2,"publicationDate":"2020-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524693/pdf/heart-int-14-34.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A Rare Case of Cor Triatriatum Sinister in Adulthood with Atypical Manifestation. 罕见的成年期三心房心绞痛，表现不典型。

IF 0.2

Heart International Pub Date : 2020-06-14 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.53

Thauler Alves de Oliveira, Renan Attílio Santos Marquiori

引用次数: 0