Heart International最新文献_第9页

Ratio of Serum Aspartate to Alanine Aminotransferase as a Marker of Isolated Coronary Artery Ectasia and its Severity. 血清天冬氨酸/丙氨酸转氨酶比值作为离体冠状动脉扩张及其严重程度的标志。

IF 0.2

Heart International Pub Date : 2020-07-31 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.43

Danesh Soltani, Samira Jafari, Haleh Ashraf, Amir Sobh-Rakhshankhah, Zahra Kolahchi, Farzad Masoudkabir, Mohammad Ali Boroumand, Ali Vasheghani-Farahani

{"title":"Ratio of Serum Aspartate to Alanine Aminotransferase as a Marker of Isolated Coronary Artery Ectasia and its Severity.","authors":"Danesh Soltani, Samira Jafari, Haleh Ashraf, Amir Sobh-Rakhshankhah, Zahra Kolahchi, Farzad Masoudkabir, Mohammad Ali Boroumand, Ali Vasheghani-Farahani","doi":"10.17925/HI.2020.14.1.43","DOIUrl":"https://doi.org/10.17925/HI.2020.14.1.43","url":null,"abstract":"Background: Several studies have reported an association between elevated liver enzymes and increased risks for developing inflammatory diseases. The aim of our study was to examine how serum liver transaminases, as inexpensive and routinely measured markers, and the De Ritis ratio are associated with the presence of coronary artery ectasia (CAE) and its severity.Methods: Participants were recruited from patients admitted to Tehran Heart Center for diagnostic coronary angiography due to suspected myocardial ischaemia. These participants also underwent concurrent laboratory routine biochemical and liver enzyme tests.Results: A total of 104 participants were included; 59 had CAE and 45 were controls without coronary artery disease (CAD). The CAE group was split into a further two subgroups: those with isolated CAE (n=27) and those with CAD and coexisting CAE (n=32). In the adjusted multivariate analysis, a lower ratio of aspartate aminotransferase to ALT (AST/ALT) was, uniquely among the variables, a statistically significant marker for isolated CAE. In the CAD + CAE group, the AST/ALT ratio was not significant after adjustments for the confounding factors. The multivariate linear regression for the Markis score showed that the AST/ALT ratio was inversely associated with the severity of CAE.Conclusions: We conclude that the AST/ALT ratio and, to some extent, ALT independently of other inflammatory factors, can be associated with the presence and severity of isolated CAE.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"43-48"},"PeriodicalIF":0.2,"publicationDate":"2020-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524754/pdf/heart-int-14-43.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent Myocardial Ischaemia due to Anaemia in a Patient with Coeliac Disease - A Case Report. 腹腔疾病患者贫血致持续性心肌缺血1例报告

IF 0.2

Heart International Pub Date : 2020-07-16 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.49

Aleksandra Gąsecka, Karolina Kruk, Adam Przybyłkowski, Tomasz Mazurek, Janusz Kochman

{"title":"Persistent Myocardial Ischaemia due to Anaemia in a Patient with Coeliac Disease - A Case Report.","authors":"Aleksandra Gąsecka, Karolina Kruk, Adam Przybyłkowski, Tomasz Mazurek, Janusz Kochman","doi":"10.17925/HI.2020.14.1.49","DOIUrl":"https://doi.org/10.17925/HI.2020.14.1.49","url":null,"abstract":"Introduction: Coeliac disease (CD) is a systemic disease of inappropriate immune response to gluten, and is associated with 10% increased risk of cardiovascular disease. Here we present a case of a young patient with persistent myocardial ischaemia due to iron-deficiency anaemia despite oral iron supplementation, who was eventually diagnosed with CD.Case report: A 36-year-old man was admitted to the cardiology department due to ST-elevation myocardial infarction of the inferior wall. Emergency coronary angiography showed occlusion of the right coronary artery and intermediate-diameter lesions in other arteries. Primary percutaneous coronary intervention with stent implantation to the right coronary artery was performed. Despite the successful intervention, the patient presented with recurrent chest pain, persistent tachycardia up to 120 beats per minute and syncope. Coronary angiography was repeated and the intermediate-diameter lesions were proved insignificant. Laboratory tests revealed microcytic anaemia with haemoglobin level of 6.5 g/dL, despite oral iron supplementation in the pre-hospital period. An emergency gastroscopy with duodenoscopy revealed flat duodenal mucosa. The duodenal biopsy confirmed the diagnosis of CD. Strict gluten-free diet and further iron supplementation were recommended. Two months later the patient presented with no recurrent chest pain and normal haemoglobin concentration.Conclusions: Diagnosis of CD with atypical presentation can be difficult. Iron-deficiency anaemia refractory to oral iron supplementation should always raise the suspicion of CD, even without typical gastrointestinal manifestation.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"49-52"},"PeriodicalIF":0.2,"publicationDate":"2020-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524602/pdf/heart-int-14-49.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clopidogrel-induced Pill Oesophagitis. 氯吡格雷引起的食道炎。

IF 0.2

Heart International Pub Date : 2020-07-14 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.56

James C Blankenship, Matthew J Shellenberger

引用次数: 1

Andexanet Alfa and its Clinical Application. Andexanet Alfa 及其临床应用。

IF 1.9

Heart International Pub Date : 2020-06-19 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.20

Fauve A Noordergraaf, Marco Alings

{"title":"Andexanet Alfa and its Clinical Application.","authors":"Fauve A Noordergraaf, Marco Alings","doi":"10.17925/HI.2020.14.1.20","DOIUrl":"10.17925/HI.2020.14.1.20","url":null,"abstract":"Factor Xa (FXa) inhibitors are widely used for stroke prevention in patients with nonvalvular atrial fibrillation, and for the treatment and prevention of deep venous thrombosis and pulmonary embolism. Compared with warfarin, individual FXa inhibitors are associated with a lower risk of major bleeding. Nevertheless, bleeding remains a feared complication of any anticoagulant therapy. Despite their demonstrated safety, implementation of FXa inhibitors in clinical practice may have been limited by the lack of a specific antidote. Recently, however, the United States Food and Drug Administration and the European Medicines Agency approved andexanet alfa for reversal of anticoagulation in patients treated with rivaroxaban or apixaban who have life-threatening or uncontrolled bleeding. This review will discuss andexanet alfa's mode of action, indication for use and efficacy, with a focus on its appropriate use in clinical practice. Unnecessary usage should be prevented as this may compromise patient safety. Assessment of potentially suitable patients by a multidisciplinary team, use according to the institutional protocol and central storage, all contribute to proper use of andexanet alfa. A practical tool to direct appropriate use of andexanet alfa is proposed.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"20-23"},"PeriodicalIF":1.9,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524750/pdf/heart-int-14-20.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Contemporary Drug-eluting Coronary Stents - Is Any Stent Better than the Others? 当代药物洗脱冠状动脉支架的比较——是否有一种支架比其他支架更好?

IF 0.2

Heart International Pub Date : 2020-06-18 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.34

William Parker, Javaid Iqbal

{"title":"Comparison of Contemporary Drug-eluting Coronary Stents - Is Any Stent Better than the Others?","authors":"William Parker, Javaid Iqbal","doi":"10.17925/HI.2020.14.1.34","DOIUrl":"https://doi.org/10.17925/HI.2020.14.1.34","url":null,"abstract":"Percutaneous coronary intervention (PCI) with implantation of a metallic drug-eluting stent (DES) is the mainstay of treatment in patients with significant coronary artery disease or acute coronary syndromes. DESs comprise a metallic platform and an anti-proliferative drug, usually released from a polymer coating. A wide range of DESs, differing in platform, polymer or drug, are currently available for clinical use. Although there are significant differences in the physical, biological and pharmacological properties of contemporary DESs, it remains unclear whether these impact meaningfully on clinical outcomes for patients undergoing PCI. Numerous randomised clinical trials have compared DESs in recent years, but these trials are typically designed to show non-inferiority, rather than superiority. Data from meta-analyses have helped to study this in larger populations, but have limitations. Improvement in stent design continues and ongoing work is exploring the effects of new innovations as well as gathering further data on existing devices. This review explores the development, properties and clinical efficacy of current-generation DESs, comparing different types where possible, whilst identifying areas of further work.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"34-42"},"PeriodicalIF":0.2,"publicationDate":"2020-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524693/pdf/heart-int-14-34.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A Rare Case of Cor Triatriatum Sinister in Adulthood with Atypical Manifestation. 罕见的成年期三心房心绞痛，表现不典型。

IF 0.2

Heart International Pub Date : 2020-06-14 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.53

Thauler Alves de Oliveira, Renan Attílio Santos Marquiori

引用次数: 0

Management of Coronary Artery Disease in the Setting of Transcatheter Aortic Valve Replacement. 经导管主动脉瓣置换术中冠状动脉疾病的处理。

IF 0.2

Heart International Pub Date : 2020-04-15 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.24

Natraj Katta, J Dawn Abbott, Ankur Kalra, Fawaz Alenezi, Andrew Goldsweig, Herbert Aronow, Poonam Velagapudi

{"title":"Management of Coronary Artery Disease in the Setting of Transcatheter Aortic Valve Replacement.","authors":"Natraj Katta, J Dawn Abbott, Ankur Kalra, Fawaz Alenezi, Andrew Goldsweig, Herbert Aronow, Poonam Velagapudi","doi":"10.17925/HI.2020.14.1.24","DOIUrl":"https://doi.org/10.17925/HI.2020.14.1.24","url":null,"abstract":"Aortic stenosis and coronary artery disease (CAD) frequently co-exist, as they share a common pathophysiology and risk factors. Due to lack of randomised controlled trials (RCTs) and exclusion of significant CAD in transcatheter aortic valve replacement (TAVR) trials, the optimal method of revascularisation of CAD in patients undergoing TAVR remains unknown. Observational studies and meta-analyses have shown varied results in outcomes for patients with CAD undergoing TAVR, and no significant difference in post-TAVR outcomes in patients who underwent revascularisation either prior to or during TAVR versus those who did not. However, some observational studies have shown that patients with lower residual SYNTAX score (rSS) post-revascularisation have better outcomes post-TAVR compared to those with higher rSS. RCTs are needed to clearly understand whether revascularisation is beneficial in these patients. Until then, management of CAD in patients undergoing TAVR must be individualised based on discussion with the heart team.","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"14 1","pages":"24-28"},"PeriodicalIF":0.2,"publicationDate":"2020-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524713/pdf/heart-int-14-24.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40583482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft in Left Main Revascularisation. 经皮冠状动脉介入治疗与冠状动脉旁路移植术在左主干血管重建中的应用。

IF 1.9

Heart International Pub Date : 2020-03-12 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.11

Timir Kumar Paul

引用次数: 0

New Consumer Guidance on Wearable Devices from the Consumer Electronics Show 2020. 2020年消费电子展关于可穿戴设备的新消费者指南。

IF 0.2

Heart International Pub Date : 2020-03-12 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.1.9

Nassir F Marrouche

引用次数: 0

Summary of Practice Considerations for Percutaneous Coronary Intervention of Left Main Bifurcation Disease. 左主干分叉疾病经皮冠状动脉介入治疗实践注意事项摘要。

IF 1.9

Heart International Pub Date : 2020-01-07 eCollection Date: 2020-01-01 DOI: 10.17925/HI.2020.14.2.69

Tanveer Rab, J Dawn Abbott, Mir Babar Basir, Azeem Latib, Gautam Kumar, Perwaiz Meraj, Kevin Croce, Rajesh Davé

引用次数: 0