Heart InternationalPub Date : 2021-12-20eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.2.106
Gustavo A Samaja, Heber Tejerina Segovia, José M Escalante, Corina Biagioni, Silvana Onorato Grats
{"title":"Endoleak after Endovascular Abdominal Aortic Aneurysm Repair Treated by Bilateral Transradial Access: Case Report.","authors":"Gustavo A Samaja, Heber Tejerina Segovia, José M Escalante, Corina Biagioni, Silvana Onorato Grats","doi":"10.17925/HI.2021.15.2.106","DOIUrl":"https://doi.org/10.17925/HI.2021.15.2.106","url":null,"abstract":"<p><p>The treatment of endovascular leaks after endovascular abdominal aortic repair can be challenging, particularly in patients with a lack of vascular access. We describe the case of a critically ill elderly patient with an endoleak resulting from structural failure of an endograft years after endovascular abdominal aortic repair. The patient was treated with an aorto-uni-iliac endoprosthesis, but a few days later a new endoleak appeared and femoral or axillar access was not feasible. We successfully treated the endoleak using a novel technique via bilateral transradial access involving simultaneous insufflation of two peripheral low-profile balloons to achieve a diameter capable of improving the apposition of the stent graft. In selected cases, bilateral radial access allows procedures to be performed that would otherwise be impossible due to the inherent limitation in sheath size that can be used in the radial artery.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 2","pages":"106-111"},"PeriodicalIF":0.2,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524746/pdf/heart-int-15-106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40654081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-12-20eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.2.94
Matthew E Li Kam Wa, Kalpa De Silva, Nilesh Pareek, Divaka Perera
{"title":"Coronary Revascularization and Out-of-hospital Cardiac Arrest: Past, Present and Future.","authors":"Matthew E Li Kam Wa, Kalpa De Silva, Nilesh Pareek, Divaka Perera","doi":"10.17925/HI.2021.15.2.94","DOIUrl":"10.17925/HI.2021.15.2.94","url":null,"abstract":"<p><p>Cardiologists and the cardiac catheter laboratory have key roles to play in the management of patients after out-of-hospital cardiac arrest (OHCA). Although immediate catheter laboratory activation is the standard of care in cardiogenic shock and ST elevation myocardial infarction, the majority of patients will present without these features and with an uncertain diagnosis. Even in the latter, early assessment and invasive management may be beneficial, but this is counterbalanced by significant resource utilization, potential to cause harm and the possibility that any diagnostic or therapeutic gains are offset by a poor neurological outcome. Past consensus on the management of the OHCA patient without ST elevation or cardiogenic shock is being challenged by emerging results from new trials in this field. Further randomized trials are ongoing, and are expected to deliver robust data from over 4,000 patients, allowing us to further refine the optimal management strategy in this challenging cohort. This article describes the benefits and pitfalls of a strategy of immediate coronary angiography in these patients, examines the recently published COACT and TOMAHAWK trials in detail, and describes a framework with which to approach the patient after resuscitated OHCA, based on the available evidence to date.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 2","pages":"94-102"},"PeriodicalIF":0.2,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524604/pdf/heart-int-15-94.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40655532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-12-10eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.2.65
Niels Mr van der Sangen, Wouter J Kikkert, José Ps Henriques, Bimmer Epm Claessen
{"title":"XIENCE Implantation Followed By Short Dual Antiplatelet Therapy: 'The New Normal'?","authors":"Niels Mr van der Sangen, Wouter J Kikkert, José Ps Henriques, Bimmer Epm Claessen","doi":"10.17925/HI.2021.15.2.65","DOIUrl":"https://doi.org/10.17925/HI.2021.15.2.65","url":null,"abstract":"<p><p>The XIENCE family of everolimus-eluting stents ranks among the most used and most widely studied drug-eluting stents worldwide. In patients at high bleeding risk undergoing non-complex percutaneous coronary intervention with these stents, a shortened dual antiplatelet therapy (DAPT) regimen of 1-3 months appears to be associated with a reduced rate of major bleeding, a similar rate of ischaemic events and a very low incidence of stent thrombosis after DAPT discontinuation compared with DAPT up to 12 months.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 2","pages":"65-66"},"PeriodicalIF":0.2,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524721/pdf/heart-int-15-65.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40654078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-12-10eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.2.73
Leonardo Marques, Silke Hopf-Jensen, Michael Preiss, Stefan Mueller-Huelsbeck
{"title":"An Update on Drug-eluting Technology in Peripheral Arteries to Treat Peripheral Arterial Disease.","authors":"Leonardo Marques, Silke Hopf-Jensen, Michael Preiss, Stefan Mueller-Huelsbeck","doi":"10.17925/HI.2021.15.2.73","DOIUrl":"https://doi.org/10.17925/HI.2021.15.2.73","url":null,"abstract":"<p><p>For the treatment of peripheral arterial disease, drug-eluting technology is a widely accepted therapeutic option, with significant reduction in intimal hyperplasia and, consequently, use of target lesion revascularization. Nevertheless, the reputation of such devices was damaged after a meta-analysis, published in December 2018, showed increased mortality in patients receiving paclitaxel-eluting devices. Although subsequent studies have failed to establish such correlation, the use of paclitaxel-eluting devices remains heavily restricted. As such, other options and drugs have been developed, for instance sirolimus. In this article we present the available data on drug-eluting technology.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 2","pages":"73-78"},"PeriodicalIF":0.2,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524588/pdf/heart-int-15-73.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40654077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-11-16eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.2.103
Haytham Enab, Colin Cunnington, Amir Zaidi
{"title":"An Unusual Cause of Pacemaker Lead Displacement: 'Reverse Ratchet' Syndrome.","authors":"Haytham Enab, Colin Cunnington, Amir Zaidi","doi":"10.17925/HI.2021.15.2.103","DOIUrl":"https://doi.org/10.17925/HI.2021.15.2.103","url":null,"abstract":"<p><p>Lead displacement is a common complication of pacemaker device implantation, often resulting in prolonged hospital stays and increased costs. The frequency of long-term lead displacement ranges between 1.8% and 8.0%. In our case, the patient did not present any symptoms and the lead displacement was seen at a relatively late stage. During a routine pacemaker follow up, it was noted that the right ventricular (RV) threshold had increased and deteriorated over time. The pacemaker box had rotated anticlockwise and the RV lead had developed a loop that eventually led to its retraction from the RV implantation position into the pulmonary artery. The patient was asymptomatic; however, he underwent RV lead revision. Patient education, opening an appropriate pocket for the size of the generator, fixing the sleeves to an appropriate tightness and securing the battery with a strong suture all can be used to avoid lead displacement.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 2","pages":"103-105"},"PeriodicalIF":0.2,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524719/pdf/heart-int-15-103.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40654083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-08-02eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.1.54
Robin Jacob, Ayaaz K Sachedina, Sachin Kumar
{"title":"Comprehensive Review of Complete Versus Culprit-only Revascularization for Multivessel Disease in ST-segment Elevation Myocardial Infarction.","authors":"Robin Jacob, Ayaaz K Sachedina, Sachin Kumar","doi":"10.17925/HI.2021.15.1.54","DOIUrl":"https://doi.org/10.17925/HI.2021.15.1.54","url":null,"abstract":"<p><p>Several organizations have developed guidelines for the management of ST-segment elevation myocardial infarction (STEMI). However, the optimal strategy regarding revascularization in the setting of multivessel disease, specifically with regards to culprit vessel versus complete revascularization, continues to evolve. While previous observational studies promoted culprit vessel-only intervention in patients with STEMI, recent randomized controlled trials suggest potential benefits with multivessel revascularization, either at the time of the index event or in a staged fashion, in patients without cardiogenic shock. This may be due to the known instability of non-culprit lesions in the setting of acute coronary syndrome, and the diffuse coronary processes involved. As additional literature examines culprit vessel versus multivessel revascularization strategies, clinicians continue to be tasked with determining optimal treatment plans for their patients and understanding the factors that promote selected revascularization strategies. This review summarizes and discusses observational studies, randomized control trials and current guidelines in order to evaluate optimal reperfusion strategies for patients presenting with STEMI in the setting of multivessel disease.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 1","pages":"54-59"},"PeriodicalIF":0.2,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524594/pdf/heart-int-15-54.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40568361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-07-21eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.1.14
Justin T Morrison, Judith Hsia, Marc P Bonaca
{"title":"Medical Therapy for Secondary Prevention of Atherothrombotic Events in Peripheral Artery Disease.","authors":"Justin T Morrison, Judith Hsia, Marc P Bonaca","doi":"10.17925/HI.2021.15.1.14","DOIUrl":"https://doi.org/10.17925/HI.2021.15.1.14","url":null,"abstract":"<p><p>Patients with peripheral artery disease (PAD) are at risk for severe morbidity and mortality, including ischaemic-related events. Furthermore, there is heterogeneity within the PAD population, where the drivers of risk for cardiovascular and limb-specific ischaemic events differ. Patients with PAD with concomitant coronary artery disease are at increased risk for cardiovascular ischaemic events, whereas patients with PAD with a prior history of lower-extremity revascularization are at increased risk for limb-specific ischaemic events. The current therapeutic challenge is identifying these risk factors to tailor therapy optimally for each patient. Additionally, the majority of our current medical therapeutics in patients with PAD have been shown to reduce atherothrombotic events, such as myocardial infarction, stroke and cardiovascular death, with a paucity of medical therapeutics specifically targeting a reduction in limb-specific ischaemic events. Over the past several years, there have been several contemporary clinical trials evaluating antithrombotic agents and their efficacy in reducing limb-specific ischaemic events. Specifically, rivaroxaban, with the addition of aspirin, has emerged as an efficacious therapeutic. In this article, we provide a review of the current clinical burden of PAD, the rationale behind current PAD medical therapeutics and the contemporary trials that have described the benefit of a novel therapeutic in PAD, rivaroxaban.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 1","pages":"14-19"},"PeriodicalIF":0.2,"publicationDate":"2021-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524742/pdf/heart-int-15-14.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40583010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-07-16eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.1.37
Michael J Reardon
{"title":"The ACURATE <i>neo</i>™ and <i>neo2</i>™ Valve Systems.","authors":"Michael J Reardon","doi":"10.17925/HI.2021.15.1.37","DOIUrl":"https://doi.org/10.17925/HI.2021.15.1.37","url":null,"abstract":"<p><p>Based on the strength of data from randomized trials and real-world clinical studies, transcatheter aortic valve replacement (TAVR) has become a popular and effective alternative to surgical valve replacement in patients with symptomatic aortic stenosis. The ACURATE <i>neo</i>™ (Boston Scientific, Marlborough, MA, USA) valve system has been commercially available for transfemoral TAVR in Europe since 2014. ACURATE <i>neo2</i>™ is an evolution of the neo design and was declared CE marked by the manufacturer in 2020. The <i>neo</i> and <i>neo2</i> valves have been studied in high-risk patients, and the currently active randomized trial for <i>neo2</i> will include over 1,500 patients of all risk categories in the USA. The goal of this review is to help inform the TAVR community about the ACURATE valve.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 1","pages":"37-41"},"PeriodicalIF":0.2,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524845/pdf/heart-int-15-37.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40568362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heart InternationalPub Date : 2021-07-16eCollection Date: 2021-01-01DOI: 10.17925/HI.2021.15.1.26
Clifton Espinoza, Debabrata Mukherjee
{"title":"Dual Antiplatelet Therapy in Patients with High Cardiovascular Risk.","authors":"Clifton Espinoza, Debabrata Mukherjee","doi":"10.17925/HI.2021.15.1.26","DOIUrl":"10.17925/HI.2021.15.1.26","url":null,"abstract":"<p><p>Coronary artery disease (CAD) is prevalent throughout the world, with a significant impact on global health. There is a vast collection of data in the medical literature relating to the topic of dual antiplatelet therapy (DAPT) in patients considered to be at high cardiovascular (CV) risk. In order to perform a narrative review of literature regarding the use of DAPT in patients with high CV risk, PubMed, Google Scholar and Embase were searched for English-language articles from 1985 to December 2020 by using the medical subject heading terms and keywords 'antiplatelet therapy' and 'high-risk cardiovascular disease', alone or in combination. Both authors critically reviewed the design, population characteristics and results of the selected studies. The topic of DAPT in patients with high CV risk is fluid and constantly evolving. The landmark trials of CURE, TRITON-TIMI 38 and PLATO provided evidence for the optimal use of DAPT in patients after acute coronary syndrome, while the CHARISMA and MATCH trials provided guidance for clinicians for their use in patients with stable coronary artery disease. The American College of Cardiology/American Heart Association focused update, published in 2016, and the European Society of Cardiology guidelines, published in 2017, were developed to provide guidance to clinicians based on the available data at the time to be able to choose the appropriate DAPT strategy that would provide patients with the maximum clinical benefit. The management of DAPT in patients with high CV risk is a challenging task, with new data on the subject constantly being reported. Balancing ischaemic benefit with potential bleeding complications adds to the complexity of managing DAPT in these patients. With all the available data and current clinical guidelines, patients deemed at high CV risk should be considered for DAPT, taking into account individual risk:benefit ratio. In most individuals with high CV risk, the net clinical benefit favours the use of DAPT.</p>","PeriodicalId":12836,"journal":{"name":"Heart International","volume":"15 1","pages":"26-36"},"PeriodicalIF":1.9,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584145/pdf/heart-int-15-26.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40583009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}