超薄支架药物洗脱支架的述评:越薄越好?

IF 1.9 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Heart International Pub Date : 2021-12-21 eCollection Date: 2021-01-01 DOI:10.17925/HI.2021.15.2.84

Maik J Grundeken, Marcel Am Beijk

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引用次数: 4

摘要

第二代药物洗脱支架(DES)被认为是经皮冠状动脉介入治疗患者血运重建的标准护理。除了聚合物和抗增殖药物外，DES的金属骨架是一个有吸引力的进一步开发目标。与传统的第二代DES相比，超薄支架DES(支架厚度≤70 μm)具有更强的柔韧性，更好的可追踪性和可交叉性。重要的是，超薄支架DES降低了支架内再狭窄的风险，从而降低了血管造影和临床再狭窄的风险。在这篇叙述性综述中，我们将讨论市售超薄支架DES的临床结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Narrative Review of Ultrathin-strut Drug-eluting Stents: The Thinner the Better?

Second-generation drug-eluting stents (DES) are considered standard of care for revascularization of patients undergoing percutaneous coronary intervention. Besides the polymer and antiproliferative drug used, the metallic backbone of DES is an attractive target for further development. Ultrathin-strut DES (≤70 μm strut thickness) are more flexible, have an improved trackability and crossability compared to conventional second-generation DES. Importantly, ultrathin-strut DES reduce the risk of in-stent restenosis, thereby decreasing the risk of angiographic and clinical restenosis. In this narrative review, we will discuss the clinical outcomes of the commercially available ultrathin-strut DES.

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来源期刊

Heart International Medicine-Cardiology and Cardiovascular Medicine

CiteScore

0.90

自引率

0.00%

发文量

审稿时长

7 weeks