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Unusual history of 'stitch'. 不寻常的 "缝合 "历史。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2023-331869
Geraldine Dahlqvist, Lancelot Marique
{"title":"Unusual history of 'stitch'.","authors":"Geraldine Dahlqvist, Lancelot Marique","doi":"10.1136/gutjnl-2023-331869","DOIUrl":"10.1136/gutjnl-2023-331869","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139912484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: Helicobacter pylori eradication, the proof is not in the symptoms-authors' reply. 致编辑的信：根除幽门螺杆菌，证据不在症状--作者的回复。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2024-331892
Christopher J Black, Peter A Paine, Alexander C Ford
{"title":"Letter to the editor: <i>Helicobacter pylori</i> eradication, the proof is not in the symptoms-authors' reply.","authors":"Christopher J Black, Peter A Paine, Alexander C Ford","doi":"10.1136/gutjnl-2024-331892","DOIUrl":"10.1136/gutjnl-2024-331892","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139432446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to McAlindon's letter. 对 McAlindon 信件的回复。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2024-331909
Lorenzo Fuccio, Laura Neilson, Leonardo Frazzoni, Colin J Rees
{"title":"Response to McAlindon's letter.","authors":"Lorenzo Fuccio, Laura Neilson, Leonardo Frazzoni, Colin J Rees","doi":"10.1136/gutjnl-2024-331909","DOIUrl":"10.1136/gutjnl-2024-331909","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Familial coaggregation of inflammatory bowel disease with cardiovascular disease: a nationwide multigenerational cohort study. 炎症性肠病与心血管疾病的家族聚集：一项全国性多代人队列研究。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2023-331632
Jiangwei Sun, Jialu Yao, Ola Olén, Jonas Halfvarson, David Bergman, Fahim Ebrahimi, Johan Sundström, Jonas F Ludvigsson
{"title":"Familial coaggregation of inflammatory bowel disease with cardiovascular disease: a nationwide multigenerational cohort study.","authors":"Jiangwei Sun, Jialu Yao, Ola Olén, Jonas Halfvarson, David Bergman, Fahim Ebrahimi, Johan Sundström, Jonas F Ludvigsson","doi":"10.1136/gutjnl-2023-331632","DOIUrl":"10.1136/gutjnl-2023-331632","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139110937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gut microbiota signatures of vulnerability to food addiction in mice and humans. 小鼠和人类易受食物成瘾影响的肠道微生物群特征。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2023-331445
Solveiga Samulėnaitė, Alejandra García-Blanco, Jordi Mayneris-Perxachs, Laura Domingo-Rodríguez, Judit Cabana-Domínguez, Noèlia Fernàndez-Castillo, Edurne Gago-García, Laura Pineda-Cirera, Aurelijus Burokas, Jose Espinosa-Carrasco, Silvia Arboleya, Jessica Latorre, Catherine Stanton, Koji Hosomi, Jun Kunisawa, Bru Cormand, Jose Manuel Fernández-Real, Rafael Maldonado, Elena Martín-García
{"title":"Gut microbiota signatures of vulnerability to food addiction in mice and humans.","authors":"Solveiga Samulėnaitė, Alejandra García-Blanco, Jordi Mayneris-Perxachs, Laura Domingo-Rodríguez, Judit Cabana-Domínguez, Noèlia Fernàndez-Castillo, Edurne Gago-García, Laura Pineda-Cirera, Aurelijus Burokas, Jose Espinosa-Carrasco, Silvia Arboleya, Jessica Latorre, Catherine Stanton, Koji Hosomi, Jun Kunisawa, Bru Cormand, Jose Manuel Fernández-Real, Rafael Maldonado, Elena Martín-García","doi":"10.1136/gutjnl-2023-331445","DOIUrl":"10.1136/gutjnl-2023-331445","url":null,"abstract":"<p><strong>Objective: </strong>Food addiction is a multifactorial disorder characterised by a loss of control over food intake that may promote obesity and alter gut microbiota composition. We have investigated the potential involvement of the gut microbiota in the mechanisms underlying food addiction.</p><p><strong>Design: </strong>We used the Yale Food Addiction Scale (YFAS) 2.0 criteria to classify extreme food addiction in mouse and human subpopulations to identify gut microbiota signatures associated with vulnerability to this disorder.</p><p><strong>Results: </strong>Both animal and human cohorts showed important similarities in the gut microbiota signatures linked to food addiction. The signatures suggested possible non-beneficial effects of bacteria belonging to the Proteobacteria phylum and potential protective effects of Actinobacteria against the development of food addiction in both cohorts of humans and mice. A decreased relative abundance of the species <i>Blautia wexlerae</i> was observed in addicted humans and of <i>Blautia</i> genus in addicted mice. Administration of the non-digestible carbohydrates, lactulose and rhamnose, known to favour <i>Blautia</i> growth, led to increased relative abundance of <i>Blautia</i> in mice faeces in parallel with dramatic improvements in food addiction. A similar improvement was revealed after oral administration of <i>Blautia wexlerae</i> as a beneficial microbe.</p><p><strong>Conclusion: </strong>By understanding the crosstalk between this behavioural alteration and gut microbiota, these findings constitute a step forward to future treatments for food addiction and related eating disorders.</p>","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11503113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141456346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Untargeted faecal metabolomics for the discovery of biomarkers and treatment targets for inflammatory bowel diseases. 非靶向粪便代谢组学用于发现炎症性肠病的生物标记物和治疗靶点。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2023-329969
Arnau Vich Vila, Jingwan Zhang, Moting Liu, Klaas Nico Faber, Rinse K Weersma
{"title":"Untargeted faecal metabolomics for the discovery of biomarkers and treatment targets for inflammatory bowel diseases.","authors":"Arnau Vich Vila, Jingwan Zhang, Moting Liu, Klaas Nico Faber, Rinse K Weersma","doi":"10.1136/gutjnl-2023-329969","DOIUrl":"10.1136/gutjnl-2023-329969","url":null,"abstract":"<p><p>The gut microbiome has been recognised as a key component in the pathogenesis of inflammatory bowel diseases (IBD), and the wide range of metabolites produced by gut bacteria are an important mechanism by which the human microbiome interacts with host immunity or host metabolism. High-throughput metabolomic profiling and novel computational approaches now allow for comprehensive assessment of thousands of metabolites in diverse biomaterials, including faecal samples. Several groups of metabolites, including short-chain fatty acids, tryptophan metabolites and bile acids, have been associated with IBD. In this <i>Recent Advances</i> article, we describe the contribution of metabolomics research to the field of IBD, with a focus on faecal metabolomics. We discuss the latest findings on the significance of these metabolites for IBD prognosis and therapeutic interventions and offer insights into the future directions of metabolomics research.</p>","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11503092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-linear association of baseline viral load with on-treatment hepatocellular carcinoma risk in chronic hepatitis B: still needs further discussion. 慢性乙型肝炎基线病毒载量与治疗后肝细胞癌风险的非线性关系：仍需进一步讨论。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2023-331443
Taiyu He, Dazhi Zhang
{"title":"Non-linear association of baseline viral load with on-treatment hepatocellular carcinoma risk in chronic hepatitis B: still needs further discussion.","authors":"Taiyu He, Dazhi Zhang","doi":"10.1136/gutjnl-2023-331443","DOIUrl":"10.1136/gutjnl-2023-331443","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
eCura and W-eCura: different scores, different populations, same goal. eCura 和 W-eCura：不同的分数，不同的人群，相同的目标。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2024-331924
Rui Morais, Diogo Libanio, João Santos-Antunes
{"title":"eCura and W-eCura: different scores, different populations, same goal.","authors":"Rui Morais, Diogo Libanio, João Santos-Antunes","doi":"10.1136/gutjnl-2024-331924","DOIUrl":"10.1136/gutjnl-2024-331924","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139574866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug targets for haemorrhoidal disease: proteome-wide Mendelian randomisation and colocalisation analyses. 痔疮疾病的药物靶点：全蛋白质组孟德尔随机化和共定位分析。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2023-330967
Shifang Li, Meijiao Gong
{"title":"Drug targets for haemorrhoidal disease: proteome-wide Mendelian randomisation and colocalisation analyses.","authors":"Shifang Li, Meijiao Gong","doi":"10.1136/gutjnl-2023-330967","DOIUrl":"10.1136/gutjnl-2023-330967","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When alcohol and fat meet, neutrophil traps form to promote liver injury. 当酒精和脂肪相遇时，就会形成中性粒细胞陷阱，促进肝脏损伤。
IF 23 1区 医学
Gut Pub Date : 2024-10-07 DOI: 10.1136/gutjnl-2024-332514
Gavin E Arteel, Bin Gao
{"title":"When alcohol and fat meet, neutrophil traps form to promote liver injury.","authors":"Gavin E Arteel, Bin Gao","doi":"10.1136/gutjnl-2024-332514","DOIUrl":"10.1136/gutjnl-2024-332514","url":null,"abstract":"","PeriodicalId":12825,"journal":{"name":"Gut","volume":null,"pages":null},"PeriodicalIF":23.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141537822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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