Frontiers in Veterinary Science最新文献

{"title":"Advances in immunological sorting of X and Y chromosome-bearing sperm: from proteome to sex-specific proteins.","authors":"Linfeng Bai, Yue Zhao, Yang Zhou, Yongli Song, Hao Xiao, Gaoping Zhao, Zhigang Wang, Xihe Li","doi":"10.3389/fvets.2025.1523491","DOIUrl":"10.3389/fvets.2025.1523491","url":null,"abstract":"<p><p>Sex determination is the developmental assignment that results from genetic factors. The sexual characters were the specific manifestations of male and female individuals under stimulation of sexual hormonal production. The fusion of an oocyte with an X chromosome-bearing sperm will lead to a female (XX), while fusion with a Y chromosome-bearing sperm will develop into a male (XY) in mammals. Sexing technology has been developed to fertilize eggs with sorted sperm, producing offspring of the desired sex. Sperm sorting enables the sex pre-determination of offspring via <i>in vitro</i> fertilization (IVF) or artificial insemination (AI) in domestic animals. Flow cytometric sorting of X and Y sperm is widely considered the most applied method for sperm sorting and has been commercially applied in cattle. However, a non-invasive, immunological method for screening X and Y sperm is considered to be a feasible approach. This review summarizes the current knowledge and techniques of sperm immunological sorting, including the preparation of antibodies, application of immunomodulators, and immunoisolation. Additionally, we focus on identifying sex-specifically expressed proteins in X and Y sperm through proteomic analysis, and verifying the sex-specific proteins using experimental techniques. Furthermore, several housekeeping proteins as loading control were discussed in immunoblotting of sperm proteins. Immunological sorting of X and Y sperm could provide a convenient, cost-effective, and highly efficient technique that can improve economic benefits and achieve an advanced level of sexing technology. This review provides insight into immunological sorting of sperm and the pre-determination of sex in farm animals.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1523491"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of intragastric administration of donkey milk on mouse immunity utilizing gut microbiomics and plasma metabolomics.","authors":"Jianwen Wang, Wanlu Ren, Zhiwen Sun, Shibo Liu, Zixiang Han, Yongfa Wang, Yaqi Zeng, Jun Meng, Xinkui Yao","doi":"10.3389/fvets.2025.1486406","DOIUrl":"10.3389/fvets.2025.1486406","url":null,"abstract":"<p><strong>Introduction: </strong>Donkey milk demonstrates closer compositional resemblance to human milk compared to bovine milk, positioning it as an optimal nutritional substitute for infants with cow's milk allergy. Furthermore, its rich profile of bioactive compounds suggests potential immunomodulatory properties. This study systematically investigated the effects of donkey milk supplementation on murine immune function and gut microbiome dynamics, thereby providing mechanistic insights to support its clinical development in functional food applications.</p><p><strong>Methods: </strong>Following daily intragastric administration of 10 mL/kg of body weight of donkey milk (DM) or distilled water (DW) to the mice for 28 consecutive days, liver tissues were harvested for immunological profiling, with concurrent collection of blood samples for plasma metabolomic analysis and fecal specimens for gut microbiome characterization. Subsequently, the modulatory effects of donkey milk supplementation on immune parameters, intestinal microbiota composition, and plasma metabolic profiles were systematically evaluated.</p><p><strong>Results: </strong>Immunity analysis revealed that intragastric administration of DM raised the levels of IL-6 and TNF-α cytokines in mouse liver. In addition, DM modulated the composition of both the murine gut microbiome and plasma metabolites. One-hundred and forty-five differentially-produced metabolites were identified, most prominently nicotinamide, L-valine, and β-estradiol, that are primarily associated with valine, leucine, and isoleucine biosynthesis and degradation, nicotinate and nicotinamide metabolism, and unsaturated fatty acid biosynthesis. Alterations at phylum, genus, and species levels were evident in the fecal microbiota of mice after intragastric administration of DM. In particular, an increased abundance of the <i>Lactobacillus</i> bacterium was observed. Correlation analysis of differential metabolites and microbiomes indicated a correspondence between <i>Falsiroseomonas</i> and <i>Salipiger</i> species and the antioxidant coenzyme Q that has the potential to activate the immune system.</p><p><strong>Conclusion: </strong>The data collectively suggest that DM may adjust the murine gut microbiome and plasma metabolites thereby potentially improving immunity in mice.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1486406"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research publications and global manufacture of veterinary vaccines against avian influenza A (2019-2023).","authors":"Aníbal Domínguez-Odio, Ernesto Rodríguez-Martínez, Mayelin Paneque Zayas, Daniel Leonardo Cala-Delgado","doi":"10.3389/fvets.2025.1394675","DOIUrl":"10.3389/fvets.2025.1394675","url":null,"abstract":"<p><p>The characteristics of the avian influenza virus and its worldwide spread have led to intense and unprecedented scientific activity and industrial production for preventive veterinary vaccines. However, knowledge gaps remain regarding the best strategies to prevent epidemiological events in the future. In this context, the present study aimed to provide a global analysis on the scientific and industrial production of avian influenza type A vaccines for farm animals and pets during the period 2019 2023. The Scopus database was used as the primary source of information (12,162 keywords, 2,437 scientific articles, 659 academic journals, and 46 countries) for the academic analysis, while technical information posted on official institutional websites (136 commercial formulations, 24 vaccines manufacturers, and 17 countries) was collected to conduct the industrial analysis. 3,045, 25.0%) exhibited the highest levels of co-occurrence in the sciences; the journal Vaccine was the most productive in terms of articles (11.8%, 288/2,437), and the countries with the most publications were the USA (25.5%, 622/2,437) and China (23.1%, 564/2,437). The most internationally marketed vaccines were inactivated (86.0%, 117/136), avian (47.1%, 64/136), and combined (52.2%, 71/136) vaccines as well as those containing Newcastle antigens (38.0%, 27/71). In conclusion, the study demonstrated the fundamental role of classical production methods (based on the use of the whole pathogen) in avian influenza A research and the production of veterinary vaccines.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1394675"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic analysis of extended-spectrum beta-lactamase-producing <i>E. coli</i> from Czech diary calves and their caretakers.","authors":"Martina Masarikova, Aneta Papouskova, Iva Sukkar, Jarmila Lausova, Darina Cejkova, Alois Cizek","doi":"10.3389/fvets.2025.1552297","DOIUrl":"10.3389/fvets.2025.1552297","url":null,"abstract":"<p><strong>Introduction: </strong>The increasing prevalence of antimicrobial resistance in livestock, particularly the dissemination of extended-spectrum beta-lactamase-producing <i>Escherichia coli</i>, poses a significant zoonotic and public health risk. This study investigates the genomic characteristics of cefotaxime-resistant <i>E. coli</i> isolates from dairy calves across 23 Czech farms and their caretakers.</p><p><strong>Materials and methods: </strong>Bacteriological cultivation on McConkey agar with cefotaxime was used for their isolation, susceptibility to selected antibiotics was determined by disc diffusion method, production of extended-spectrum beta-lactamases (ESBL) was demonstrated by double disc synergy test. The PCR was applied to confirm the presence of selected genes encoding resistance to some beta-lactams and genes encoding resistance to quinolones carried on plasmids. Using whole-genome sequencing, we evaluated resistance genotypes, sequence types, serotypes, plasmid replicons, and virulence genes.</p><p><strong>Results and discussion: </strong>Among 266 rectal samples obtained from the calves, 128 (48%) harbored cefotaxime-resistant <i>E. coli</i>. Whole-genome analysis revealed <i>bla_CTX-M</i> genes in 91% (116/128) of isolates, with <i>bla</i> _{<i>CTX-M</i>-14} (44%) and <i>bla</i> _{<i>CTX-M</i>-1} (34%) being the dominant variants. Other beta-lactamase gene <i>bla_TEM-1b</i> was found in 40% (51/128) of isolates. Notably, no cephamycin resistance genes have been identified. The plasmid-mediated quinolone resistance (PMQR) gene <i>qnrS1</i> was present at 21% (27/128) of isolates. The colistin resistance gene <i>mcr-1</i> was found in a single ST2325 isolate. Sequence typing revealed significant clonal diversity, with 21 different STs detected among 68 sequenced isolates. ST10 was the most prevalent (27%), followed by ST69 (12%), ST29 (7%) and others. The phylogenetic distribution showed a predominance of commensal groups A (54%) and B1 (21%). The most common serotypes included O101:H9 (21%), O15:H18 (12%), H12, and O70:H11 (7%). Analysis of plasmid content revealed a complex distribution of 18 distinct plasmid replicon types, especially IncF, followed by Col-type and IncI1-type plasmids. Cross-species transmission was indicated by the detection of clonal strains shared between calves and caretakers, notably ST10-O101:H9 and ST34-O68:H30. The prevalence of high-risk clones and the presence of mobile resistance elements underscore the urgent need for stringent monitoring, antimicrobial stewardship, and improved biosecurity measures in livestock environments like increased caution and personal hygiene of animal handlers to mitigate the spread of resistant <i>E. coli</i> between animals and humans.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1552297"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into the role of bioactive plants for lambs infected with <i>Haemonchus contortus</i> parasite.","authors":"Michaela Komáromyová, Daniel Petrič, Klára Demčáková, Matej Leško, Klaudia Čobanová, Michal Babják, Alžbeta Königová, Tetiana Kuzmina, Sylwester Ślusarczyk, Paulina Izabela Fortuna, Anna Łukomska, Pola Sidoruk, Adam Cieslak, Zora Váradyová, Marián Várady","doi":"10.3389/fvets.2025.1566720","DOIUrl":"10.3389/fvets.2025.1566720","url":null,"abstract":"<p><p>Bioactive plants provide therapeutic and prophylactic effects to ruminants. We determined the effect of grazing on natural meadow grassland enriched with experimentally sown chicory (<i>Cichorium intybus</i>) on parasitological status, pasture larval infectivity, antioxidant parameters, and the histology of abomasal tissue in lambs experimentally infected with the parasitic gastrointestinal nematode (GIN) <i>Haemonchus contortus.</i> We also qualitatively identified the main polyphenols in the meadow grassland and phenolic metabolites in the feces of the lambs. Sixteen lambs were orally infected with approximately 5,000 infective larvae (L3) of <i>H. contortus</i>. The lambs were divided into two groups: lambs grazing on a plot consisting exclusively of meadow pasture which serves as control group and lambs grazing on a plot where approximately 25% of a meadow grassland was reclaimed with chicory. The experimental period was 144 days. The number of eggs per gram (EPG) of feces was quantified on D21, D34, D48, D62, D76, D89, D103, D118, D131, and D144 post-infection. Pasture contamination with <i>H. contortus</i> L3 was examined. EPG in both groups of lambs was highest at D34. Egg shedding was significantly lower in both groups from D48 onwards, with a reduction of >95% from D103 onwards. Pasture contamination with L3 was highest at D41 but was then significantly lower in both groups. The total antioxidant capacity, the activity of glutathione peroxidase and the concentration of malondialdehyde in the serum changed significantly during the experiment (<i>p</i> < 0.003, < 0.001, and < 0.016, respectively). At least 54 species of meadow plants were identified on both pasture plots; plant bioactive compounds identified were mainly phenolic acids, flavonoids, and glucosides. Phenolic metabolites (e.g., coumaric acid, chicory acid, salvigenin, and esters of gallic acid) were identified in the feces of the lambs. In some lambs, the morphological observation identified small histopathological changes in the abomasal tissues typical of hemonchosis. Both the natural meadow pasture and the pasture enriched with experimentally sown chicory slowed the dynamics of GIN infection and pasture contamination with L3 by mobilizing the antioxidant defensive system and gradually increasing the resistance of the infected lambs, probably due to the beneficial effects of plant bioactive substances.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1566720"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetisation transfer, T1 and T2* relaxation in canine menisci of elderly dogs-an <i>ex vivo</i> study in stifle joints.","authors":"Lena Bunzendahl, Amir Moussavi, Martina Bleyer, Stephan Neumann, Susann Boretius","doi":"10.3389/fvets.2025.1521684","DOIUrl":"10.3389/fvets.2025.1521684","url":null,"abstract":"<p><p>Magnetic resonance imaging (MRI) is widely used in human medicine, offering multiple contrast mechanisms to visualise different tissue types. It is also gaining importance in veterinary medicine, including diagnosing joint disorders. The menisci of the stifle joint play a crucial role in the development of osteoarthritis (OA), and multi-parameter MRI of the menisci may aid in early OA diagnosis, potentially improving therapeutic outcomes. In a previous <i>ex vivo</i> study, we measured T2 relaxation times in menisci of elderly dogs with mild histological signs of degeneration but no clinical symptoms of lameness. As no significant changes in T2 relaxation times were observed in relation to histological scores, the present study extends this investigation by exploring more advanced MR parameters-including T1 relaxation time, T2* relaxation time, magnetisation transfer ratio (MTR), and magnetisation transfer saturation (MTsat)-to assess their potential for detecting early microstructural changes in the menisci. While T2* relaxation times and MTR showed no significant variation across histological scores, MTsat values increased with higher proteoglycan staining. In contrast, the apparent T1 relaxation time (T1app) was lower in menisci with elevated proteoglycan scores and increased with higher cellularity scores. The correlation between MTsat and proteoglycan content suggests that MTsat, along with T1app, could be a promising parameter for characterising the extracellular matrix. However, further research is needed to validate these findings.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1521684"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The biological functions of proanthocyanidin and its application in pig production.","authors":"Aiying Yu, Lingli Sun, Lian Chen, Dan Wang, Zhiyi Li, Yuan Wang, Zhenjiang Wang, Sen Lin","doi":"10.3389/fvets.2025.1565501","DOIUrl":"10.3389/fvets.2025.1565501","url":null,"abstract":"<p><p>Proanthocyanidins (PACs) are natural polyphenolic compounds widely distributed in various plants, which are mixtures of oligomers and polymers formed by the polymerization of different numbers of catechins and epicatechins. PACs exhibit a range of biological activities, including antioxidant, anti-inflammatory, anti-cancer, anti-atherosclerotic, hypoglycemic, and antihypertensive effects, as well as the ability to regulate intestinal flora and promote fat metabolism. These properties render PACs highly promising for applications in the food, pharmaceutical, and cosmetic industries, garnering substantial interest from researchers globally. Additionally, PACs demonstrate significant nutritional benefits in animal husbandry. Dietary PACs can enhance animal growth, mitigate oxidative stress, decrease feeding expenses, and offer an environmentally friendly, antibiotic-free alternative. Therefore, PACs have great application potential in the field of pig production. This article reviews the basic properties, biological functions, and research status and application in pig production of PACs, aiming to provide theoretical guidance for the development of substitute antibiotic feed additives.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1565501"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transthoracic fine-needle aspiration of the lungs, and bacterial culture with antimicrobial susceptibility testing used in diagnosing bacterial pneumonia in dogs and cats: 14 dogs and 2 cats (2009-2021).","authors":"Aleksandra Preibisz, Claudia Sabine Schwedes","doi":"10.3389/fvets.2025.1521793","DOIUrl":"10.3389/fvets.2025.1521793","url":null,"abstract":"<p><p>Transthoracic fine-needle aspiration of the lungs (TFNA) combined with positive bacterial culture is used less frequently than airway lavage in diagnosing bacterial pneumonia in dogs and cats. This retrospective study evaluated TFNA results and bacterial culture findings in 14 dogs (1 dog twice) and two cats with bacterial pneumonia. Bacterial culture yielded positive results in 9/16 (56.3%) of samples. Only 1/11 (9.1%) of isolated bacterial species showed resistance to empiric treatment (amoxicillin with clavulanate). Six patients without prior antimicrobial treatment had negative bacterial cultures, despite the presence of intracellular bacteria on cytology samples. For patients with suspected bacterial pneumonia, we should consider performing both cytological examination and bacterial culture of lung aspirates, with careful interpretation of the results. Bacterial culture should be considered regardless of ongoing or previous antibiotic treatment, and even in cases where intracellular bacteria are not identified on cytology. Based on our antimicrobial susceptibility findings, first-line empirical treatment with amoxicillin with clavulanate might be an appropriate choice in most of cases regardless of the previous treatment.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1521793"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of applications of deep learning in veterinary diagnostics and animal health.","authors":"Sam Xiao, Navneet K Dhand, Zhiyong Wang, Kun Hu, Peter C Thomson, John K House, Mehar S Khatkar","doi":"10.3389/fvets.2025.1511522","DOIUrl":"10.3389/fvets.2025.1511522","url":null,"abstract":"<p><p>Deep learning (DL), a subfield of artificial intelligence (AI), involves the development of algorithms and models that simulate the problem-solving capabilities of the human mind. Sophisticated AI technology has garnered significant attention in recent years in the domain of veterinary medicine. This review provides a comprehensive overview of the research dedicated to leveraging DL for diagnostic purposes within veterinary medicine. Our systematic review approach followed PRISMA guidelines, focusing on the intersection of DL and veterinary medicine, and identified 422 relevant research articles. After exporting titles and abstracts for screening, we narrowed our selection to 39 primary research articles directly applying DL to animal disease detection or management, excluding non-primary research, reviews, and unrelated AI studies. Key findings from the current body of research highlight an increase in the utilisation of DL models across various diagnostic areas from 2013 to 2024, including radiography (33% of the studies), cytology (33%), health record analysis (8%), MRI (8%), environmental data analysis (5%), photo/video imaging (5%), and ultrasound (5%). Over the past decade, radiographic imaging has emerged as most impactful. Various studies have demonstrated notable success in the classification of primary thoracic lesions and cardiac disease from radiographs using DL models compared to specialist veterinarian benchmarks. Moreover, the technology has proven adept at recognising, counting, and classifying cell types in microscope slide images, demonstrating its versatility across different veterinary diagnostic modality. While deep learning shows promise in veterinary diagnostics, several challenges remain. These challenges range from the need for large and diverse datasets, the potential for interpretability issues and the importance of consulting with experts throughout model development to ensure validity. A thorough understanding of these considerations for the design and implementation of DL in veterinary medicine is imperative for driving future research and development efforts in the field. In addition, the potential future impacts of DL on veterinary diagnostics are discussed to explore avenues for further refinement and expansion of DL applications in veterinary medicine, ultimately contributing to increased standards of care and improved health outcomes for animals as this technology continues to evolve.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1511522"},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health impacts of African swine fever outbreaks on veterinarians in the Philippines.","authors":"Hannah J Bakke, Alejandro D Perez, Ruth Miclat-Sonaco, Andres M Perez, Rachel A Schambow","doi":"10.3389/fvets.2025.1519270","DOIUrl":"10.3389/fvets.2025.1519270","url":null,"abstract":"<p><p>Emergence of African swine fever (ASF) in the Philippines in 2019 caused substantial impacts on animal health and its pig industry. To control ASF, strict policies were applied including zoning and depopulation of infected herds. While ASF's severe impacts on pigs are well recognized, its potential impacts to public health are often overlooked. ASF is not a food safety concern and does not infect humans, but it has the potential to affect mental, emotional, and social well-being during emergency response. Veterinarians may be particularly at risk due to their role in depopulation of pigs and other distressing tasks. The objective here was to assess the effects of the ASF outbreaks on Filipino veterinarians' mental and social well-being. A questionnaire was created and anonymously administered to 13 Filipino veterinarians attending a training workshop in December 2023. All participants had experience responding to the ASF outbreaks. Then, the summary responses were discussed with the entire group, allowing for clarification and verification. Two-by-two contingency tables and Fisher's exact test were used to explore associations between responses. The top five negative signs reported by >50% participants were \"reduced energy,\" \"reduced sleep,\" \"new feelings of hopelessness or sadness,\" \"new feelings of anger or frustration,\" and \"reduced enjoyment of life.\" Some veterinarians also reported negative social interactions such as antagonism and blame toward public veterinarians. These results highlight the often-overlooked impacts of ASF on mental and social well-being and indicate the need for mental health support for veterinarians as part of comprehensive ASF mitigation efforts.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1519270"},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}