Future cardiology最新文献_第6页

The effect of sodium-glucose co-transporter 2 inhibitors on clinical outcomes after acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials. 钠-葡萄糖共转运蛋白2抑制剂对急性心肌梗死后临床结局的影响：随机对照试验的系统回顾和荟萃分析

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-02-12 DOI: 10.1080/14796678.2025.2464449

Ubaid Khan, Ahmed Mazen Amin, Amira Mohamed Taha, Yehya Khlidj, Majd M AlBarakat, Mariam Elewidi, Mohamed Abuelazm, Mustafa Turkmani, Basel Abdelazeem, Rida Laeeq

{"title":"The effect of sodium-glucose co-transporter 2 inhibitors on clinical outcomes after acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials.","authors":"Ubaid Khan, Ahmed Mazen Amin, Amira Mohamed Taha, Yehya Khlidj, Majd M AlBarakat, Mariam Elewidi, Mohamed Abuelazm, Mustafa Turkmani, Basel Abdelazeem, Rida Laeeq","doi":"10.1080/14796678.2025.2464449","DOIUrl":"10.1080/14796678.2025.2464449","url":null,"abstract":"Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2is) reduce cardiovascular events, especially in diabetic patients. However, the cardioprotective effects of early SGLT2i administration following acute myocardial infarction (AMI) remain unclear.Objective: This study aims to investigate the impact of SGLT2is on clinical outcomes in patients post-AMI.Methods: A comprehensive search was conducted in PubMed, CENTRAL, WOS, Scopus, and EMBASE up to April 2024. Risk ratio (RR) was used for dichotomous outcomes and mean difference (MD) for continuous outcomes, with 95% confidence intervals (CI).Results: Seven studies with 11,407 patients were included. SGLT2is did not significantly reduce the incidence of major adverse cardiovascular events (MACE) (RR = 0.94, 95% CI [0.68, 1.29], p = 0.69), all-cause mortality (RR = 1.01, 95% CI [0.84, 1.21], p = 0.93), or stroke (RR = 0.61, 95% CI [0.29,1.28], p = 0.19). However, SGLT2is significantly reduced the risk of heart failure (RR = 0.76, 95% CI [0.63, 0.91], p < 0.01) and improved left ventricular ejection fraction (MD = 1.86, 95% CI [1.58, 2.14], p < 0.01).Conclusion: In post-AMI patients, SGLT2is do not significantly affect MACE or mortality but are associated with reduced heart failure risk and improved ejection fraction.Protocol registration: PROSPERO identifier number: CRD42024506806.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"177-190"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current landscape of congenital heart disease management during pregnancy. 妊娠期先天性心脏病管理的现状。

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-01-28 DOI: 10.1080/14796678.2025.2458404

Gurleen Wander, Mark R Johnson

引用次数: 0

Current landscape of clinical management for systemic light chain amyloidosis. 系统性轻链淀粉样变性的临床管理现状。

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-01-31 DOI: 10.1080/14796678.2025.2460392

Andrew Staron, Vaishali Sanchorawala

引用次数: 0

A nuanced scrutiny of the segmental renal artery spectral Doppler in "Pickering" the right diagnosis. 在“皮克林”的正确诊断中，对肾动脉节段谱多普勒进行细致入微的检查。

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-01-23 DOI: 10.1080/14796678.2025.2457933

Adee Elhamdani, Kirtivardhan Vashistha, Laith Alhuneafat, Tala Altarawneh, Robert Biederman, John Travis Wilson, Wilbert S Aronow, Vinh Nguyen

引用次数: 0

Assessing angiographic results of saline autotransfusion and thrombus aspiration in STEMI patients. 评估STEMI患者生理盐水自身输注和血栓抽吸的血管造影结果。

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-03-04 DOI: 10.1080/14796678.2025.2472581

Rekha V, Sudhakar Rao, Krishnananda Nayak, Manjoosha M, Jyothi Samanth, Padmakumar R

{"title":"Assessing angiographic results of saline autotransfusion and thrombus aspiration in STEMI patients.","authors":"Rekha V, Sudhakar Rao, Krishnananda Nayak, Manjoosha M, Jyothi Samanth, Padmakumar R","doi":"10.1080/14796678.2025.2472581","DOIUrl":"10.1080/14796678.2025.2472581","url":null,"abstract":"Background: Effective myocardial reperfusion in ST-Elevation Myocardial Infarction (STEMI) remains challenging despite advancements in primary percutaneous coronary intervention (PCI). This study evaluates the impact of thrombus aspiration (TA) and saline autotransfusion (SAT) compared to standard PCI (NOTA) on coronary flow dynamics and myocardial perfusion.Research design and method: This prospective cohort study enrolled 157 STEMI patients who underwent primary PCI. Participants were divided into two groups: TA+SAT (n = 80) and NOTA (n = 77). Clinical parameters such as blood pressure, ejection fraction, ST-segment resolution, thrombolysis in myocardial infarction (TIMI) flow grades, corrected TIMI frame count (CTFC), and myocardial infarction (MI) location were assessed.Results: Patients in the TA+SAT group exhibited significantly better short-term myocardial reperfusion, as indicated by superior ST-segment resolution (p = 0.010) and lower CTFC values (p < 0.001). Blood pressure was significantly lower in the TA+SAT group (p = 0.042). However, ejection fraction improvement at one month was not statistically significant. TIMI and TMPG flow grades were comparable between groups.Conclusion: The TA+SAT approach demonstrated improved coronary flow dynamics and better short-term myocardial reperfusion in STEMI patients without additional pharmacological interventions. These findings suggest that TA+SAT may serve as a valuable adjunct to PCI, warranting further investigation into its long-term clinical benefits.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"237-243"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of single-pill ACE inhibitor/ccb combination for hypertension: an Algerian view via the nominal group technique. 单片ACE抑制剂/ccb联合治疗高血压的作用：阿尔及利亚人通过名义组技术观察。

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-02-12 DOI: 10.1080/14796678.2025.2465218

Brahim Kichou, Abed Bouraghda, Hadj Mohamed Ali Lahmar, Sofiane Amara, Yazid Aoudia, Yasmina Benchabi, Farid Haddoum, Adjia Kachenoura, Nadia Laredj, Leila Manamani, Mohamed Tahar Chafik Bouafia, Mohamed Chettibi

{"title":"The role of single-pill ACE inhibitor/ccb combination for hypertension: an Algerian view via the nominal group technique.","authors":"Brahim Kichou, Abed Bouraghda, Hadj Mohamed Ali Lahmar, Sofiane Amara, Yazid Aoudia, Yasmina Benchabi, Farid Haddoum, Adjia Kachenoura, Nadia Laredj, Leila Manamani, Mohamed Tahar Chafik Bouafia, Mohamed Chettibi","doi":"10.1080/14796678.2025.2465218","DOIUrl":"10.1080/14796678.2025.2465218","url":null,"abstract":"Around one-third of adults in Algeria have hypertension, but > 40% are unaware they have the disease, and of those receiving treatment, only ~ 20-30% have adequate blood pressure (BP) control. Recommended starting treatment is an angiotensin converting enzyme inhibitor (ACEi) or angiotensin receptor blocker plus a calcium channel blocker (CCB) or diuretic. A single-pill combination of perindopril/amlodipine (ACEi/CCB) recently became available in Algeria. Twelve Algerian hypertension experts reviewed the clinical evidence regarding this therapeutic combination to determine its potential role for hypertension management in Algeria. The evidence indicated that this combination reduces cardiovascular outcomes and visit-to-visit BP variability, effectively controls 24-hour BP, and is well tolerated. In conclusion, the perindopril/amlodipine SPC provides a valuable new treatment option for hypertension in Algeria.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"155-166"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of novel predictors for early detection of cancer therapeutics-related cardiac dysfunction. 验证早期检测癌症治疗相关心功能障碍的新预测因子。

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-02-16 DOI: 10.1080/14796678.2025.2466379

Marwan S Mahmoud, Moustafa Morsy, Mohamed Abdel Ghany, Naglaa K Idriss, Hatem Abdelrahman Helmy, Yehia T Kishk

{"title":"Validation of novel predictors for early detection of cancer therapeutics-related cardiac dysfunction.","authors":"Marwan S Mahmoud, Moustafa Morsy, Mohamed Abdel Ghany, Naglaa K Idriss, Hatem Abdelrahman Helmy, Yehia T Kishk","doi":"10.1080/14796678.2025.2466379","DOIUrl":"10.1080/14796678.2025.2466379","url":null,"abstract":"Background: Early identification of cardiotoxicity of chemotherapy is crucial. Gene expression is considered a promising tool.Aim: To validate the new speckle tracking values, high-sensitive (Hs) troponin and expression of TNNI3K and RyR2 genes for early detection of cardiotoxicity.Methods: Fifty patients with cancer breast on Anthracycline chemotherapy were subjected to speckle tracking echocardiography and Hs troponin measurement. Relative expression of TNNI3K and RyR2 genes were determined by RT-PCR.Results: Fifty female patients with age (43.89 ± 6.4) were included. Fourteen patients (28%) developed cardiotoxicity, diagnosed by decrease GLS > 15%. Compared to GLS, Hs-Troponin has sensitivity 73%, specificity 100%, PPV 78.5% and NPV 100%. Cutoff point of GLS > 10% had sensitivity 95%, specificity 78%, PPV 81% and NPV 84%. Using a cutoff of 24% change in TNNI3K Expression; sensitivity 100%, specificity 74%, PPV 79.5% and NPV 100%. Using a cutoff of 25% in RYR-2 expression; sensitivity 67% and specificity 59% with less PPV and NPV (62% and 64%). Adding GLS change >10% to Hs troponin and TNNI3K expression resulted in highest sensitivity (100%) and specificity (95.5%) with 96% PPV and 100% NPV.Conclusion: Cutoff point of GLS > 10%, Hs-Troponin and TNNI3K gene expression are reliable test for early detection of cardiotoxicity.Trial registration number (irb): 042024100222.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"229-235"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case report: ST-elevation myocardial infarction complications. How far will you go? 1例报告：st段抬高型心肌梗死并发症。你会走多远？

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-02-26 DOI: 10.1080/14796678.2025.2471732

Rumbinaitė Eglė, Karčiauskas Dainius, Jakuška Povilas, Vajauskas Donatas, Mamedov Arslan, Jakuškaitė Gabrielė, Bolys Ramūnas, Žūkaitė Gabrielė, Jankauskienė Loreta, Benetis Rimantas, Žaliūnas Remigijus

{"title":"Case report: ST-elevation myocardial infarction complications. How far will you go?","authors":"Rumbinaitė Eglė, Karčiauskas Dainius, Jakuška Povilas, Vajauskas Donatas, Mamedov Arslan, Jakuškaitė Gabrielė, Bolys Ramūnas, Žūkaitė Gabrielė, Jankauskienė Loreta, Benetis Rimantas, Žaliūnas Remigijus","doi":"10.1080/14796678.2025.2471732","DOIUrl":"10.1080/14796678.2025.2471732","url":null,"abstract":"Herein, we review the critical role of a multi-disciplinary team approach in managing the intricate complications of ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Mechanical circulatory support (MCS) implantation represents a potentially life-saving intervention, often serving as a bridge to heart transplantation (HTx). However, complications from prior interventions, in patients receiving MCS due to STEMI-CS, may present additional challenges to successful HTx candidacy. A 63-year-old male suffered out-of-hospital cardiac arrest and was hospitalized due to acute anterior STEMI-CS. Emergency percutaneous coronary intervention was performed in the setting of cardiopulmonary resuscitation. Despite successful revascularization and subsequent optimal medical therapy hemodynamic status remained compromised, the decision was made to implant a HeartMate 3 (HM3) left ventricular assist device (LVAD) as a bridge to HTx. HM3 LVAD was implanted without complications and patient was weaned from mechanical ventilation. The later postoperative period was complicated by infections leading to the LVAD-related complications. Moreover, the patient experienced repeated episodes of stridor, which were attributed to significant tracheal stenosis (due to temporary tracheostomy). Finally, a suitable heart donor was found and a successful HTx was performed.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"217-221"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of renal denervation in microcirculation: focusing on coronary microvascular dysfunction. 肾去神经对微循环的影响：以冠状动脉微血管功能障碍为重点。

IF 1.6

Future cardiology Pub Date : 2025-03-01 Epub Date: 2025-02-09 DOI: 10.1080/14796678.2025.2464478

Kyriakos Dimitriadis, Nikolaos Pyrpyris, Fotis Tatakis, Konstantinos Kyriakoulis, Daphne Elpy Pitsiori, Eirini Beneki, Christos Fragkoulis, Dimitrios Konstantinidis, Anastasios Kollias, Konstantinos Aznaouridis, Konstantinos Tsioufis

{"title":"The effect of renal denervation in microcirculation: focusing on coronary microvascular dysfunction.","authors":"Kyriakos Dimitriadis, Nikolaos Pyrpyris, Fotis Tatakis, Konstantinos Kyriakoulis, Daphne Elpy Pitsiori, Eirini Beneki, Christos Fragkoulis, Dimitrios Konstantinidis, Anastasios Kollias, Konstantinos Aznaouridis, Konstantinos Tsioufis","doi":"10.1080/14796678.2025.2464478","DOIUrl":"10.1080/14796678.2025.2464478","url":null,"abstract":"Arterial hypertension is one of the most prevalent cardiovascular pathologies worldwide. Considering the increased rates of uncontrolled hypertension and treatment non-adherence, catheter-based methods, with the most prominent being renal denervation, have been recently included in international guidelines for the management of the pathology, naming the method the third pillar in hypertension management. However, sympathetic overactivation is not only a major pathophysiologic driver in hypertension, but in other cardiovascular pathologies as well. Considering the effect of renal denervation in hypertension-mediated target organ damage, as well as the pleotropic effects of this modality, recent evidence have evaluated the modality in coronary microvascular dysfunction (CMD). Interestingly, despite preclinical data showcase a benefit of renal denervation in microcirculatory homeostasis, with enhancement of endothelial-mediated vasodilation and reduction of inflammation, these effects have failed to be translated into clinical benefit, with the limited, to date, non-interventional studies in coronary microcirculation reporting neutral effects. Therefore, this review aims to delineate the pathophysiological processes which relate microvascular dysfunction with hypertension, discuss the effect of the procedure in hypertension-mediated target organ damage, analyze preclinical and clinical data on the safety and efficacy of renal denervation in improving microcirculatory indices, as well as provide future directions for this novel field.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"245-256"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of in-clinic assessment of 6MWT by conventional method and using wearable sensors for patients with ATTR-CM. 常规方法与可穿戴传感器对atr - cm患者临床6MWT评估的比较

IF 1.6

Future cardiology Pub Date : 2025-02-01 Epub Date: 2025-01-29 DOI: 10.1080/14796678.2025.2457881

Prem Soman, Michel G Khouri, Daniel Lenihan, Alex Reyentovich, Brett W Sperry, Kristen Sowalsky, Yun Bai, Jing Du, Leonid Katz, Suresh Siddhanti, Jonathan C Fox

{"title":"Comparison of in-clinic assessment of 6MWT by conventional method and using wearable sensors for patients with ATTR-CM.","authors":"Prem Soman, Michel G Khouri, Daniel Lenihan, Alex Reyentovich, Brett W Sperry, Kristen Sowalsky, Yun Bai, Jing Du, Leonid Katz, Suresh Siddhanti, Jonathan C Fox","doi":"10.1080/14796678.2025.2457881","DOIUrl":"10.1080/14796678.2025.2457881","url":null,"abstract":"Introduction: The 6-minute walk test (6MWT) is used to assess submaximal exercise capacity in clinical trials. Conducting the 6MWT can be challenging when patients cannot visit the clinic due to physical/travel limitations. This pilot study assessed the feasibility of conducting the 6MWT using wearable sensors for patients with transthyretin amyloid cardiomyopathy.Methods: Participants were enrolled in the phase 3 ATTRibute-CM trial. Sensors were positioned on patients' feet and lower back during the 6MWT. The 6-minute walk distance (6MWD) was compared with the distance measured by a trained observer during a concurrent conventional test. Pearson and concordance correlation coefficients were estimated.Results: Twelve participants from five centers participated; 11 had evaluable data. Mean 6MWD was 330.3 m (conventional method) and 335.1 m (wearable sensors); mean difference (SD) was 4.7 m (10.95). Pearson and concordance correlation coefficients for 6MWD were 0.998 (95% CI: 0.992-0.999) and 0.997 (95% CI: 0.991-0.999), respectively.Conclusions: The 6MWD measured using wearable sensors and by the conventional method were closely correlated. Conducting the 6MWT with wearable sensors may be feasible and as reliable as the conventional method in a monitored clinic setting. Whether at-home 6MWD measured by wearable sensors correlates with in-clinic monitoring deserves further study.Clinical trial registration: ClinicalTrials.gov identifier is NCT03860935.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"75-81"},"PeriodicalIF":1.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0