Future Science OA最新文献

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Clinical impact of multidrug-resistant bacterial infections in patients with cirrhosis. 肝硬化患者耐多药细菌感染的临床影响。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0160
Nouha Trad, Ghanem Mohamed, Sondes Bizid, Hatem Ben Abdallah, Riadh Bouali, Mohamed Nabil Abdelli
{"title":"Clinical impact of multidrug-resistant bacterial infections in patients with cirrhosis.","authors":"Nouha Trad, Ghanem Mohamed, Sondes Bizid, Hatem Ben Abdallah, Riadh Bouali, Mohamed Nabil Abdelli","doi":"10.2144/fsoa-2023-0160","DOIUrl":"10.2144/fsoa-2023-0160","url":null,"abstract":"<p><p><b>Aim:</b> Recently, the emergency of multidrug-resistant organisms (MDRO) has complicated the management of bacterial infections (BI) in cirrhosis. We aimed to assess their clinical impact on patients with decompensated cirrhosis. <b>Methods:</b> A retrospective study included consecutive cirrhotic patients hospitalized for acute decompensation (AD) between January 2010 and December 2019. <b>Results:</b> A total of 518 AD admissions in 219 patients were included, with 260 BI episodes (50.2%). MDRO prevalence was 38.2% of the total isolates. Recent antibiotic use (OR = 4.91), nosocomial infection (OR = 2.95), and healthcare-associated infection (OR = 3.45) were their main risk factors. MDROs were associated with empiric treatment failure (OR = 23.42), a higher prevalence of sepsis (OR = 4.93), ACLF (OR = 3.42) and mortality. <b>Conclusion:</b> The clinical impact of MDROs was pejorative, with an increased risk of empiric treatment failure, organ failure and death.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic scores in primary biliary cholangitis. 原发性胆汁性胆管炎的预后评分。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0203
Ramzi Tababi, Soumaya Mrabet, Imen Akkari, Raida Harbi, Elhem Ben Jazia
{"title":"Prognostic scores in primary biliary cholangitis.","authors":"Ramzi Tababi, Soumaya Mrabet, Imen Akkari, Raida Harbi, Elhem Ben Jazia","doi":"10.2144/fsoa-2023-0203","DOIUrl":"10.2144/fsoa-2023-0203","url":null,"abstract":"<p><p><b>Aim:</b> Evaluating prognostic scores' utility in predicting ursodeoxycholic acid (UDCA) biochemical response (BR) and long-term liver-related complications in primary biliary cholangitis (PBC) patients. <b>Patients & methods:</b> This retrospective single-center study included 50 predominantly female PBC patients (median age: 56) on UDCA treatment. BR was defined by Paris II criteria. Liver-related complications during a median 76-month follow-up were assessed. APRI, ALBI, Mayo, GLOBE and UK-PBC scores were calculated. <b>Results:</b> 64% achieved BR, while 40% experienced liver-related complications. All scores showed good BR prediction (concordance statistics: 0.76-0.94) and excellent negative predictive values for 5-year liver complications (concordance statistics: 0.73-0.89). <b>Conclusion:</b> Implementing these scores in clinical practice is encouraged due to their effectiveness in predicting BR- and liver-related events.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low dose insulin infusion versus the standard dose in children with diabetic ketoacidosis: a meta-analysis. 糖尿病酮症酸中毒患儿低剂量胰岛素输注与标准剂量胰岛素输注的比较:一项荟萃分析。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0137
Mohamed Mohamed Belal, Basma Badrawy Khalefa, Eslam Mohammed Rabea, Mazen Negmeldin Aly Yassin, Mohamed Nabih Bashir, Malak Mohamed Abd El-Hameed, Omar Elkoumi, Saad Mohamed Saad, Loubna Mohamed Saad, Mohamed Hamouda Elkasaby
{"title":"Low dose insulin infusion versus the standard dose in children with diabetic ketoacidosis: a meta-analysis.","authors":"Mohamed Mohamed Belal, Basma Badrawy Khalefa, Eslam Mohammed Rabea, Mazen Negmeldin Aly Yassin, Mohamed Nabih Bashir, Malak Mohamed Abd El-Hameed, Omar Elkoumi, Saad Mohamed Saad, Loubna Mohamed Saad, Mohamed Hamouda Elkasaby","doi":"10.2144/fsoa-2023-0137","DOIUrl":"10.2144/fsoa-2023-0137","url":null,"abstract":"<p><p><b>Aim:</b> This systematic review aims to consolidate findings from current clinical trials that compare the effectiveness of insulin infusion at 0.05 IU/kg/h versus 0.1 IU/kg/h in managing pediatric diabetic ketoacidosis. <b>Methods:</b> We searched several databases, including PubMed, Embase, Scopus, Cochrane Central and Web of Science. Our primary outcomes were time to reach blood glucose ≤250 mg/dl and time to resolution of acidosis. Secondary outcomes included rate of blood glucose decrease per hour, incidence of hypoglycemia, hypokalemia, treatment failure, and cerebral edema. <b>Results & conclusion:</b> The present study establishes that a low insulin dose exhibits comparable efficacy to the standard dosage for managing pediatric patients suffering from diabetic ketoacidosis, with a lower incidence of complications.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyroid storm-induced acute liver dysfunction and portal hypertension in a patient with Graves' disease: a case report. 甲状腺风暴诱发巴塞杜氏病患者急性肝功能异常和门静脉高压:病例报告。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0180
Mouna Medhioub, Amal Khsiba, Moufida Mahmoudi, Asma Ben Mohamed, Manel Yakoubi, Emna Haouet, Lamine Hamzaoui
{"title":"Thyroid storm-induced acute liver dysfunction and portal hypertension in a patient with Graves' disease: a case report.","authors":"Mouna Medhioub, Amal Khsiba, Moufida Mahmoudi, Asma Ben Mohamed, Manel Yakoubi, Emna Haouet, Lamine Hamzaoui","doi":"10.2144/fsoa-2023-0180","DOIUrl":"10.2144/fsoa-2023-0180","url":null,"abstract":"<p><p>Thyroid storm is a life-threatening condition associated with multiorgan dysfunction and decompensation. We report the case of a 41-year-old woman having Graves' disease presented with thyroid storm complicated with liver dysfunction and portal hypertension in the absence of congestive heart failure or known liver disease. After successful therapeutic management, all biological, clinical and morphological abnormalities regressed.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gabapentinoid prescriptions for neuropathic and musculoskeletal pain in Lebanon. 黎巴嫩治疗神经痛和肌肉骨骼痛的加巴喷丁诺类处方。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0219
Joe Rassi, Stephanie Khazaka, Sani Hlais, Stephanie Rassi, Mohammad Daher, Toufic Samaha
{"title":"Gabapentinoid prescriptions for neuropathic and musculoskeletal pain in Lebanon.","authors":"Joe Rassi, Stephanie Khazaka, Sani Hlais, Stephanie Rassi, Mohammad Daher, Toufic Samaha","doi":"10.2144/fsoa-2023-0219","DOIUrl":"10.2144/fsoa-2023-0219","url":null,"abstract":"<p><p><b>Aim:</b> The purpose of this study is to analyze the different characteristics of gabapentinoids prescription by Lebanese orthopedics surgeons. <b>Methods:</b> This is an observational, cross-sectional study using a survey which was carried out in collaboration with the Lebanese Orthopedic Society over a 3-month period. <b>Results:</b> Forty-two orthopedic surgeons responded, most of them prescribing gabapentinoids in their daily practice with only half of the patients feeling relief after taking them. Furthermore, most of the surgeons prescribed these drugs for patients above 18 years old and for both acute and chronic pain. <b>Conclusion:</b> Even though almost half of the patients do not experience relief after taking gabapentinoids, these drugs are becoming more and more prescribed.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Financial hardship after cancer: revision of a conceptual model and development of patient-reported outcome measures. 癌症后的经济困难:概念模型的修订和患者报告结果测量方法的开发。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0229
Salene Mw Jones, Jean Yi, Nora B Henrikson, Laura Panattoni, Veena Shankaran
{"title":"Financial hardship after cancer: revision of a conceptual model and development of patient-reported outcome measures.","authors":"Salene Mw Jones, Jean Yi, Nora B Henrikson, Laura Panattoni, Veena Shankaran","doi":"10.2144/fsoa-2023-0229","DOIUrl":"10.2144/fsoa-2023-0229","url":null,"abstract":"<p><p><b>Aim:</b> This qualitative study refined a conceptual model of financial hardship and developed measures corresponding to model constructs. <b>Methods:</b> Eighteen women with breast cancer recruited through a comprehensive cancer center completed interviews. A qualitative framework analysis was conducted of the interviews. <b>Results:</b> Participants experienced varying levels of financial hardship. Protective factors included good health insurance, work accommodations and social support. Participants worried about cancer care costs and employment. Programs for alleviating financial hardship had high administrative burdens. Four preliminary financial hardship measures were developed: coping, impacts, depression and worry. <b>Conclusion:</b> Reducing administrative barriers to benefits could reduce financial hardship after cancer. More research is needed on the effects of out-of-network/formulary care and denials of coverage and to validate the measures.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early laparoscopic cholecystectomy in severely comorbid patients with acute cholecystitis: results of a monocentric study. 急性胆囊炎严重合并症患者的早期腹腔镜胆囊切除术:单中心研究结果。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0185
Mohamed S Jarrar, Malek Barka, Mehdi Chahed, Radhouane Toumi, Ameni Beizig, Mohamed H Mraidha, Fehmi Hamila, Sabri Youssef
{"title":"Early laparoscopic cholecystectomy in severely comorbid patients with acute cholecystitis: results of a monocentric study.","authors":"Mohamed S Jarrar, Malek Barka, Mehdi Chahed, Radhouane Toumi, Ameni Beizig, Mohamed H Mraidha, Fehmi Hamila, Sabri Youssef","doi":"10.2144/fsoa-2023-0185","DOIUrl":"10.2144/fsoa-2023-0185","url":null,"abstract":"<p><p><b>Aim:</b> The aim is to evaluate laparoscopic cholecystectomy safety based on American Society of Anesthesiologists score for acute cholecystitis in patients with comorbidities. <b>Patients & methods:</b> This is retrospective study of patients who underwent laparoscopic cholecystectomy for acute cholecystitis between 2003 and 2021. According to their respective ASA-score, patients were divided into group 1: ASA1-2 and group 2: ASA3-4. <b>Results:</b> We collected 578 patients. Even though the gangrenous forms were more frequent and the operative time was longer in group 2, laparoscopic cholecystectomy seems safe and effective. We didn't observe any differences in terms of intraoperative incidents, open conversion rate, or postoperative complications compared with other patients. <b>Conclusion:</b> ASA3-4 patients with acute cholecystitis don't face elevated risks of complications or mortality during laparoscopic cholecystectomy.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of histology's performance compared with PCR in the diagnosis of Helicobacter pylori infection. 评估组织学与 PCR 在幽门螺旋杆菌感染诊断中的性能比较。
IF 2.5
Future Science OA Pub Date : 2024-05-14 eCollection Date: 2024-01-01 DOI: 10.2144/fsoa-2023-0217
Manel Moalla, Lassaad Chtourou, Basma Mnif, Slim Charfi, Hend Smaoui, Mon Boudabous, Leila Mnif, Ali Amouri, Hela Gdoura, Adnene Hammami, Tahya Boudawara, Nabil Tahri
{"title":"Assessment of histology's performance compared with PCR in the diagnosis of <i>Helicobacter pylori</i> infection.","authors":"Manel Moalla, Lassaad Chtourou, Basma Mnif, Slim Charfi, Hend Smaoui, Mon Boudabous, Leila Mnif, Ali Amouri, Hela Gdoura, Adnene Hammami, Tahya Boudawara, Nabil Tahri","doi":"10.2144/fsoa-2023-0217","DOIUrl":"10.2144/fsoa-2023-0217","url":null,"abstract":"<p><p><b>Aim:</b> Histology is the most widely used test to detect <i>H. pylori</i>. PCR is less used but allows the detection of both infection and antibiotics' resistance. <b>Methods:</b> We conducted a monocentric cross-sectional study, collecting 97 symptomatic patients to assess the diagnostic performance of histology in the detection of <i>H. pylori</i> infection compared with PCR. <b>Results:</b> Sensitivity of histology in comparison with PCR was 81.5% and specificity was 56.3%. A history of anti-<i>H. pylori</i> therapy intake, as well as the density of the bacterium on the gastric sample and the presence of gastric atrophy, were significantly correlated to the PCR's result in terms of <i>H. pylori</i> detection. <b>Conclusion:</b> Thus, histology can be considered as an efficient test compared with PCR in <i>H. pylori</i> detection.</p>","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A bibliometric analysis of the 100 most-influential papers in the field of anti-diabetic drugs 抗糖尿病药物领域最具影响力的 100 篇论文的文献计量分析
IF 2.5
Future Science OA Pub Date : 2024-01-31 DOI: 10.2144/fsoa-2023-0230
Fatima Azam, Muhammad Hamza Dawood, Aroosa Roshan, Maryam Urooj, Zoha Khan, M. O. Larik, Fatima Mustafa Lakdawala, Ahad Yousuf Moulvi, Ifrah Salim, Mehak Abbas Zaidi, Alizeh Imran
{"title":"A bibliometric analysis of the 100 most-influential papers in the field of anti-diabetic drugs","authors":"Fatima Azam, Muhammad Hamza Dawood, Aroosa Roshan, Maryam Urooj, Zoha Khan, M. O. Larik, Fatima Mustafa Lakdawala, Ahad Yousuf Moulvi, Ifrah Salim, Mehak Abbas Zaidi, Alizeh Imran","doi":"10.2144/fsoa-2023-0230","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0230","url":null,"abstract":"Aim: We analyzed the 100 most-cited articles on all anti-diabetic drugs. A comprehensive literature review found no bibliometrics on this. Methods: Two researchers independently extracted articles from Scopus and ranked them by citation count as the ‘top 100 most-cited’. Results: The median number of citations is 1385.5. Most articles are from the USA (n = 59). Insulin has the most papers (n = 24). Majority (n = 76) were privately funded and contained at least one conflict of interest (n = 66). The New England Journal of Medicine has the most publications (n = 44). Male authors made majority of both first and last authorship positions. Conclusion: This study aims to aid in directing future research and in reducing biases.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140470549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body fluids biomarkers associated with prognosis of acute ischemic stroke: progress and prospects 与急性缺血性脑卒中预后相关的体液生物标志物:进展与展望
IF 2.5
Future Science OA Pub Date : 2024-01-31 DOI: 10.2144/fsoa-2023-0142
Fengmang Jiang, Junhua Li, Simin Yu, Jinli Miao, Wenmin Wang, Xiaohong Xi
{"title":"Body fluids biomarkers associated with prognosis of acute ischemic stroke: progress and prospects","authors":"Fengmang Jiang, Junhua Li, Simin Yu, Jinli Miao, Wenmin Wang, Xiaohong Xi","doi":"10.2144/fsoa-2023-0142","DOIUrl":"https://doi.org/10.2144/fsoa-2023-0142","url":null,"abstract":"Acute ischemic stroke (AIS) is one of the most common strokes posing a grave threat to human life and health. Predicting the prognosis of AIS allows for an understanding of disease progress, and a better quality of life by making individualized treatment scheme. In this paper, we conducted a systematic search on PubMed, focusing on the relevant literature in the last 5 years. Summarizing the candidate prognostic biomarkers of AIS in body fluids such as blood, urine, saliva and cerebrospinal fluid is often of great significance for the management of acute ischemic stroke, which has the potential to facilitate early diagnosis, treatment, prevention and long-term outcome improvement.","PeriodicalId":12568,"journal":{"name":"Future Science OA","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140477373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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