Gastrointestinal endoscopy最新文献

{"title":"Enhancing endoscopic sleeve gastroplasty research: addressing missing data, subgroup variations, and unadjusted confounders","authors":"Zhen Deng MD, Lincheng Duan PhD, Tao Li MD","doi":"10.1016/j.gie.2024.12.031","DOIUrl":"10.1016/j.gie.2024.12.031","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 6","pages":"Pages 1276-1277"},"PeriodicalIF":6.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined phosphorus-32 implantation and chemotherapy versus chemotherapy alone for locally advanced pancreatic cancer: a propensity-score weighted landmark analysis.","authors":"Amanda H Lim, Darshan Nitchingham, Jana Bednarz, Madison Bills, Laxmi Lanka, Berry Allen, Alvin Tan, Rohit Joshi, William Hsieh, Benjamin Crouch, Joshua Zobel, John-Edwin Thomson, Euling Neo, Romina Safaeian, Edmund Tse, Christopher K Rayner, Andrew Ruszkiewicz, Jayden Wong, Nimit Singhal, Dylan Bartholomeusz, Frank Weilert, Nam Q Nguyen","doi":"10.1016/j.gie.2025.04.054","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.054","url":null,"abstract":"<p><strong>Background and aims: </strong>Combined standard chemotherapy and phosphorus-32 (³²P) microparticle intra-tumoral implantation has revealed encouraging results in locally advanced pancreatic cancer (LAPC). We compared chemotherapy and ³²P implantation with standard therapy (chemotherapy +/- chemoradiotherapy) using a propensity-score weighted analysis (PSWA).</p><p><strong>Method: </strong>We conducted a retrospective cohort study comparing clinical outcomes of combined chemotherapy and endoscopic ultrasound (EUS)-guided ³²P implantation against standard therapy for patients with LAPC from 2 tertiary hospitals. Landmark analysis was used to address immortal time bias. PSWA was applied to reduce bias due to confounding. The primary outcome was overall survival within 30 months after first-line treatment initiation, with treatment effect expressed as restricted mean survival time (RMST).</p><p><strong>Results: </strong>104 patients were considered. The landmark date was designated as 3 months after initiation of first-line chemotherapy. After excluding patients who died before the landmark, or had ³²P implantation after it, 86 patients were included (35 combination vs. 51 standard). The RMST within 30 months after chemotherapy commencement was an estimated 189 days longer for patients with combination therapy (527.2 [95% CI 437.8-634.8] vs. 338.0 [95%CI 284.2-402]; p=0.002). The local progression free RMST within 30 months was estimated to be 168.6 days (95%CI 79.9-257.2) longer and the probability of downstaging was 23.9% higher (95%CI 6.3-41.3, p=0.008) in patients treated with combination therapy.</p><p><strong>Conclusion: </strong>In this comparative study between combined chemotherapy and ³²P microparticles implantation with standard chemotherapy for patients with LAPC, the combination showed better survival, disease control and downstaging. The outcomes highlight the need for a randomized controlled trial.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manifestations and Endoscopic Treatment of Eosinophilic Esophageal Myositis (with video).","authors":"Nan Dai, Chang-Qing Guo, Yang Shi, Xin-Guang Cao","doi":"10.1016/j.gie.2025.04.048","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.048","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elongated duodenal spindle cell lipoma.","authors":"Guoxin Wang, Qifang Wu, Xijin Wang, Mingfu Tong","doi":"10.1016/j.gie.2025.04.046","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.046","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A duodenal spindle cell lipoma removed by endoscopic resection.","authors":"Xiaolin Li, Zhilan Liu, Xiaohong Xue, Yaping Wang","doi":"10.1016/j.gie.2025.04.047","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.047","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 2024 top 10 list of endoscopy topics in medical publishing: an annual review by the American Society for Gastrointestinal Endoscopy Editorial Board.","authors":"Melissa Martinez, Michael J Bartel, Tiffany Chua, Lara Dakhoul, Hala Fatima, Brooke Glessing, Dennis Jensen, Luis F Lara, Brianna Shinn, Micheal Tadros, Edward Villa, John R Saltzman","doi":"10.1016/j.gie.2025.04.004","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.004","url":null,"abstract":"<p><p>Using a systematic literature search of original articles published during 2024 in Gastrointestinal Endoscopy (GIE) and other high-impact medical and gastroenterology journals, the GIE Editorial Board of the American Society for Gastrointestinal Endoscopy compiled a list of the top 10 most significant topic areas in general and advanced GI endoscopy during the year. Each GIE Editorial Board member was directed to consider 3 criteria in generating candidate topics: significance, novelty, and impact on clinical practice. Subject matter consensus was facilitated by the Chair through electronic voting of the entire GIE Editorial Board. The top 10 identified topics collectively represent advances in the following endoscopic areas: glucagon-like peptide-1 receptor agonists and endoscopy, advances in AI in endoscopy, ergonomics in endoscopy, peroral endoscopic myotomy, bariatric and metabolic endoscopy, endoscopic resection in the colon, gastric intestinal metaplasia and endoscopy, inflammatory bowel disease and endoscopy, GI bleeding risk stratification and endoscopic therapies, and therapeutic EUS. Board members were assigned a topic area and summarized relevant and important articles, thereby generating this overview of the \"top 10\" endoscopic advances of 2024.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopy in Inflammatory Bowel Disease: What Every Endoscopist Should Know.","authors":"Gursimran S Kochhar, Partha Pal","doi":"10.1016/j.gie.2025.04.044","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.044","url":null,"abstract":"<p><strong>Background and aims: </strong>Endoscopic advancements have revolutionized the diagnosis, monitoring, and management of inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Ileocolonoscopy remains the gold standard for initial diagnosis, guiding therapeutic strategies and providing baseline disease characterization.</p><p><strong>Methods: </strong>The available literature was systematically reviewed, including articles focusing on the role of endoscopy in IBD diagnosis, disease activity assessment (endoscopic scoring), post-operative monitoring, and therapeutic interventions assessing their impact on reducing surgical intervention and optimizing disease management.</p><p><strong>Results: </strong>Endoscopic scoring systems, including the Mayo Endoscopic Subscore, Ulcerative Colitis Endoscopic Index of Severity, and Simple Endoscopic Score for Crohn's Disease, provide standardized evaluation of disease activity and treatment response. Knowledge of these scoring systems is essential in the modern era for managing the IBD. Post-operative surgical anatomy can pose a different challenge, and understanding of these is very important for a practicing gastroenterologist. In recent years, role of endoscopy has evolved from diagnosis to therapeutic interventions such as endoscopic balloon dilation, stricturotomy, and stenting to effectively manage complications like strictures and fistulas, minimizing the need for surgery. Advanced endoscopic techniques, including mucosal resection, submucosal dissection, and full-thickness resection, have transformed the management of dysplasia, reducing the risk of colectomy.</p><p><strong>Conclusion: </strong>This review underscores the critical role of endoscopy in optimizing patient outcomes through accurate diagnosis, therapeutic precision, and the integration of emerging technologies.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Top tips for endoscopic-guided nasojejunal tube placement (with video).","authors":"Nonthalee Pausawasdi","doi":"10.1016/j.gie.2025.04.043","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.043","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved clinical outcomes of patients with cirrhosis and acute variceal bleeding over the last two decades.","authors":"Nikolaus Pfisterer, Florian Riedl, Michael Schwarz, Benedikt Simbrunner, Nina Dominik, Georg Kramer, Mathias Jachs, Lukas Hartl, Florian Putre, Lukas Ritt, Mattias Mandorfer, Philipp Holzmueller, Christian Madl, Michael Trauner, Thomas Reiberger","doi":"10.1016/j.gie.2025.04.045","DOIUrl":"https://doi.org/10.1016/j.gie.2025.04.045","url":null,"abstract":"<p><strong>Background and aims: </strong>Acute variceal bleeding (AVB), a severe complication of portal hypertension, may cause death in patients with cirrhosis. We investigated whether outcomes after AVB have improved over time.</p><p><strong>Methods: </strong>Data from 406 patients with cirrhosis with AVB (2000-2022) from two Viennese centers were analyzed for recurrent bleeding, 6-week mortality, and 1-year transplant-free survival (TFS).</p><p><strong>Results: </strong>Recurrent bleeding rates within 6 weeks decreased from 19.4% to 11.8% (HR:0.59, 95%CI: 0.35-0.97;p=0.049) and bleeding-related mortality decreased from 23.6% to 18.3% (HR:0.68, 95%CI: 0.44-1.06;p=0.099). 1-year TFS after AVB improved from 63.8% to 73.7% (HR:0.68; 95%CI: 0.47-0.97;p=0.041). Higher Child-Pugh scores were associated with increased risk for bleeding (aOR:1.68) and mortality (aOR:1.69, both p<0.001). Non-selective beta-blockers reduced 1-year mortality risk (aOR:0.48,p0.038).</p><p><strong>Conclusion: </strong>Recurrent bleeding and mortality rates after AVB improved over the last two decades but remain substantial, highlighting the need for continued efforts to optimize outcomes for patients with cirrhosis.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPUTER-AIDED DETECTION WITH OR WITHOUT MUCOSAL-EXPOSURE DEVICES IN COLONOSCOPY: A SYSTEMATIC REVIEW AND META-ANALYSIS WITH TRIAL SEQUENTIAL ANALYSIS","authors":"Erica U. Holanda,&nbsp;Gilmara C. Meine,&nbsp;Eduardo C. Barbosa,&nbsp;Paula Santo,&nbsp;Angélica L. Nau,&nbsp;Karollyna M. Moore,&nbsp;Rafael D. Picon","doi":"10.1016/j.gie.2025.03.093","DOIUrl":"10.1016/j.gie.2025.03.093","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 5","pages":"Pages S51-S52"},"PeriodicalIF":6.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}