Gastrointestinal endoscopy最新文献

{"title":"Rescue Treatment with intraluminal endoscopic vacuum therapy for Ileal Pouch-Anal Anastomotic Dehiscence in a Young Patient with Ulcerative Colitis (with Video).","authors":"Antonio Z Gimeno-García, María de la Cruz Correa, Marta Carrillo, David Nicolás-Pérez","doi":"10.1016/j.gie.2026.09.030","DOIUrl":"https://doi.org/10.1016/j.gie.2026.09.030","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Vacuum Therapy Successfully Treats a Large Radiation-Related Low Rectal Anastomotic Ulcer After Local Excision for Rectal Cancer.","authors":"Wenliang Sun, Junjie Tang, Qing Teng, Dongbing Zhou, Yunhong Tian","doi":"10.1016/j.gie.2026.09.031","DOIUrl":"https://doi.org/10.1016/j.gie.2026.09.031","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of gastric length of myotomy during POEM on the incidence of gastroesophageal reflux: A randomized controlled trial.","authors":"Zaheer Nabi, Naveen Adepu, Pradev Inavolu, Jayanta Samanta, Hardik Rughwani, Aniruddha Pratap Singh, Partha Pal, Santosh Darisetty, Rama Kotla, Rajesh Goud, Rakesh Kalpala, Manu Tandan, Rajesh Gupta, Mohan Ramchandani, Sundeep Lakhtakia, D Nageshwar Reddy","doi":"10.1016/j.gie.2026.09.018","DOIUrl":"https://doi.org/10.1016/j.gie.2026.09.018","url":null,"abstract":"<p><strong>Background and aims: </strong>Peroral endoscopic myotomy (POEM) is an effective treatment for achalasia cardia, but gastroesophageal reflux disease (GERD) remains a significant concern. The length of gastric myotomy may influence reflux outcomes, but high-quality data are lacking. This randomized controlled trial compared the incidence of GERD after short versus long gastric myotomy (SGM vs LGM) during POEM.</p><p><strong>Methods: </strong>In this randomized trial, we compared SGM (gastric myotomy <3 cm) with LGM (gastric myotomy≥3 cm) during POEM in cases with type I or II achalasia. The primary endpoint was significant reflux esophagitis defined as Los Angeles (LA) grade B or higher esophagitis at 6 months follow-up. Secondary endpoints included esophageal acid exposure (≥6% total acid exposure time [AET]) on 24-hour pH monitoring, reflux symptoms, proton pump inhibitor (PPI) use, Eckardt score, esophageal emptying, and high-resolution manometry parameters.</p><p><strong>Results: </strong>A total of 100 patients were randomly assigned to undergo either POEM with SGM (50 patients) or LGM (50 patients). Baseline characteristics were similar between groups. At 6 months, significant reflux esophagitis occurred in 24% (12/50) of SGM patients versus 44% (22/50) of LGM patients (p = 0.035; odds ratio, 2.45; 95% CI, 1.04-5.79). Upright acid exposure was significantly lower in the SGM group (median 0.75% vs 3.2%; p = 0.036). No differences were observed in reflux symptoms, PPI use, total AET, or clinical efficacy between groups.</p><p><strong>Conclusions: </strong>SGM significantly reduces the incidence of LA grade ≥B esophagitis at 6 months following POEM, without differences in symptom burden, acid exposure, or clinical efficacy. (ClinicalTrials.gov number, NCT05500196).</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Artificial Intelligence for Invasion-Depth Prediction in Superficial Upper Gastrointestinal Cancer: A Diagnostic Test Accuracy Meta-Analysis.","authors":"Hyuk Lee, Yang Won Min, Sehun Kim, Hyosoon Yoo, Tae Jun Kim","doi":"10.1016/j.gie.2026.09.022","DOIUrl":"https://doi.org/10.1016/j.gie.2026.09.022","url":null,"abstract":"<p><strong>Background and aims: </strong>Pre-resection prediction of submucosal invasion is pivotal for endoscopic submucosal dissection (ESD) candidate selection in early gastric and esophageal cancers. We performed a diagnostic test accuracy meta-analysis of artificial intelligence (AI) for invasion-depth prediction.</p><p><strong>Methods: </strong>PubMed/MEDLINE, Embase, Cochrane CENTRAL, and Web of Science were searched through 11 June 2026. Eligible studies applied AI to endoscopic images or videos of superficial upper gastrointestinal cancers with histopathological reference standards. Pooled sensitivity and specificity were estimated with a bivariate random-effects model; subgroup and meta-regression analyses examined validation framework, histology, AI architecture, and imaging modality. Risk of bias was assessed with QUADAS-2.</p><p><strong>Results: </strong>Twenty-six studies were eligible; 18 (14 gastric adenocarcinoma, 4 esophageal squamous cell carcinoma) contributed to the primary pool of 6,568 validation/test patients or lesions. Pooled sensitivity was 0.77 (95% CI 0.71-0.82) and specificity 0.88 (0.85-0.90); positive and negative likelihood ratios were 6.30 and 0.26. Externally validated specificity was lower than internally validated specificity (0.85 vs. 0.93); validation framework was the only covariate significantly associated with performance in prespecified meta-regression (specificity pseudo-R² 77.9%), whereas AI architecture and imaging modality were not. In within-study paired comparisons (n = 8 studies), mean per-study sensitivity was higher for AI alone than for unassisted endoscopists (82.5% vs. 63.8%; +18.7 percentage points; paired t = 3.29, p = 0.013); specificity did not differ significantly. Limited AI-assisted reader-comparison data were directionally consistent with a second-reader role but remained exploratory.</p><p><strong>Conclusions: </strong>Endoscopic AI shows clinically meaningful, but validation-dependent, accuracy for invasion-depth prediction, supporting stronger rule-in than rule-out utility for submucosal invasion. Its most plausible near-term role is second-reader support rather than stand-alone determination of ESD candidacy; independent patient-level external validation should be considered essential before clinical deployment. (PROSPERO registration: CRD420261400366).</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are the benefits attributed to Endocut Q for hot snare resection in the colorectum real or myth?","authors":"Douglas K Rex, Daniel von Renteln, John J Guardiola, Cesare Hassan, Heiko Pohl","doi":"10.1016/j.gie.2026.09.020","DOIUrl":"https://doi.org/10.1016/j.gie.2026.09.020","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of novel VAC-Stent in management of upper gastrointestinal post-surgical leaks: results from a large multicenter study in tertiary referral centers.","authors":"F P Zito, A D'Alessandro, G Dell'Anna, A Martino, S Saviano, F V Mandarino, F Bernardi, A De Leone, M Di Serafino, S Giovine, S Danese, R Rosati, G De Roberto, M Maregatti, V Colace, S Mangiafico, G Donatelli, H Bertani, F Pirozzi, D Esposito, C Giardiello, G Galasso, R Manta, G Lombardi","doi":"10.1016/j.gie.2026.09.021","DOIUrl":"https://doi.org/10.1016/j.gie.2026.09.021","url":null,"abstract":"<p><strong>Background and aim: </strong>Self-expandable metal stents (SEMS) and endoscopic vacuum therapy (EVT) represent the mainstay of endoscopic treatment for leaks of the upper gastrointestinal (UGI) tract. The VAC-Stent GIᵀᴹ (MicroTech, Düsseldorf, Germany) is a novel device that combines the principles of both SEMS and EVT. In this study, we evaluate the efficacy and safety of VAC-Stent in the management of post-surgical UGI wall defects.</p><p><strong>Methods: </strong>A retrospective multicenter study was performed in seven Italian endoscopic centers between June 2023 and January 2025. A total of 81 patients with evidence of UGIpost-surgical leak were enrolled (71.6% male; age range 32 - 83 yrs; mean age 63.5 ± 11.8 yrs). VAC-Stent removal or substitution was scheduled within 7 days from the deployment; continuous suction with negative pressure of - 125 mmHg was applied; leak closure was radiologically and/or endoscopically confirmed.</p><p><strong>Results: </strong>A total of 156 VAC-Stents GIᵀᴹ was implanted in 81 patients (range 1-7; mean stent per patient 2.0 ± 1.0), with a mean treatment duration of 12.7 ± 6.3 days (range 7 - 41 days). Six out 81 patients were excluded because of premature death unrelated to stent failure. Deployment was successful in 100% of cases (150/150). Mean diameter of the wall defect was 19.6 ± 18.2 mm and complete healing was achieved in 85.3% of patients (64/75). Enteral nutrition was provided in 53.3% of the cases. One case of late bleeding occurred after stent deployment and was managed conservatively; no cases of recurrence were recorded during follow-up.</p><p><strong>Conclusions: </strong>VAC-stent GIᵀᴹ represents a safe and effective approach in treating anastomotic leaks following upper GI surgery.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Competing mortality, not age or sex, may explain the loss of benefit from colonoscopy in adults aged 80 to 85 years.","authors":"Christos Zavos","doi":"10.1016/j.gie.2026.07.043","DOIUrl":"https://doi.org/10.1016/j.gie.2026.07.043","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic decompression of congenital diaphragmatic incarceration.","authors":"Satomi Otaki, Naoki Oshima, Shunji Ishihara","doi":"10.1016/j.gie.2026.09.016","DOIUrl":"10.1016/j.gie.2026.09.016","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response.","authors":"Jahnvi Dhar, Jayanta Samanta","doi":"10.1016/j.gie.2026.07.033","DOIUrl":"https://doi.org/10.1016/j.gie.2026.07.033","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An endoscopic solution for a medically refractory Crohn's manifestation.","authors":"Dr Samantha Ehrlich, Dr Jakob Saidman, Dr Arun Swaminath","doi":"10.1016/j.gie.2026.09.010","DOIUrl":"https://doi.org/10.1016/j.gie.2026.09.010","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}