{"title":"Refining endoscopic resection criteria for early gastric cancer in elderly patients","authors":"Yinfang Wu MM, Weixing Xu MM","doi":"10.1016/j.gie.2024.10.020","DOIUrl":"10.1016/j.gie.2024.10.020","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 4","pages":"Pages 921-922"},"PeriodicalIF":6.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consideration of the risk score model of lymph node metastasis in early gastric cancer based on EUS","authors":"Guanjun Zhang MD, PhD, Mingyang Li MD, PhD","doi":"10.1016/j.gie.2024.10.042","DOIUrl":"10.1016/j.gie.2024.10.042","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 4","pages":"Pages 923-924"},"PeriodicalIF":6.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tae-Geun Gweon MD, PhD , Hyun Gun Kim MD, PhD , Yunho Jung MD, PhD , Seong Ran Jeon MD, PhD , Soo-Young Na MD, PhD , Yoo Jin Lee MD, PhD , Tae Ho Kim MD, PhD
{"title":"Safety of cold snare resection techniques for removal of polyps in the small colon in patients taking clopidogrel and aspirin: a Korean Association for the Study of Intestinal Diseases prospective multicenter study","authors":"Tae-Geun Gweon MD, PhD , Hyun Gun Kim MD, PhD , Yunho Jung MD, PhD , Seong Ran Jeon MD, PhD , Soo-Young Na MD, PhD , Yoo Jin Lee MD, PhD , Tae Ho Kim MD, PhD","doi":"10.1016/j.gie.2024.10.014","DOIUrl":"10.1016/j.gie.2024.10.014","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Polypectomy is a procedure associated with a high risk of bleeding. Guidelines recommend uninterrupted aspirin use during polypectomy, whereas cessation of clopidogrel 5 to 7 days before polypectomy is recommended. The cold snare resection (CSR) technique, with or without submucosal injection, is considered safer than conventional polypectomy using electrocoagulation for postpolypectomy bleeding. In this study, we compared the bleeding adverse events associated with CSR between clopidogrel and aspirin users.</div></div><div><h3>Methods</h3><div>This multicenter prospective cohort study was conducted in 5 academic hospitals in Korea and included clopidogrel and aspirin users who underwent polypectomy. Antiplatelet agents were used without interruption, with ≤3 days of interruption defined as continuous use. The primary endpoint was delayed bleeding, which was defined as bleeding occurring several hours after polypectomy, whereas immediate bleeding was defined as bleeding requiring hemostasis 2 minutes after polypectomy. Risk factors for immediate bleeding were investigated for each polyp.</div></div><div><h3>Results</h3><div>Finally, 263 patients (509 polyps) were included, including those receiving clopidogrel (n=129) and aspirin (n=134). The rates of delayed bleeding per patient in the clopidogrel and aspirin groups were .8% and .7%, respectively, meeting noninferiority (rate difference, .03%; 95% confidence interval, –2.07 to 2.13). A total of 100 cases of hemostasis (19.8%) were performed in 68 patients after polypectomy. Immediate bleeding risk factors were female sex, end-stage renal disease, submucosal injection before resection, and polyp size ≥5 mm.</div></div><div><h3>Conclusions</h3><div>This multicenter prospective study demonstrated the safety of CSR in patients treated with uninterrupted clopidogrel and aspirin. (Clinical trial registration number: NCT04328987.)</div></div>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 4","pages":"Pages 866-876"},"PeriodicalIF":6.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142462632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and safety of endoscopic hemostasis with a self-assembling peptide solution in patients with colonic diverticular bleeding: a multicenter pilot study (with video)","authors":"Daisuke Yamaguchi MD, PhD , Naoyuki Tominaga MD, PhD , Genki Mori MD , Takeshi Yasuda MD, PhD , Takahiro Yukimoto MD, PhD , Yosuke Minoda MD, PhD , Koichi Miyahara MD, PhD , Kensei Ohtsu MD, PhD , Yoichiro Ito MD, PhD , Kohei Yamanouchi MD, PhD , Kasumi Gondo MD , Tadahiro Nomura MD , Yuichiro Tanaka MD, PhD , Michito Tomonaga MD , Mitsuru Esaki MD, PhD , Takuya Shimamura MD, PhD , Yuki Takeuchi MD, PhD , Motohiro Esaki MD, PhD","doi":"10.1016/j.gie.2024.11.006","DOIUrl":"10.1016/j.gie.2024.11.006","url":null,"abstract":"<div><h3>Background and Aims</h3><div>PuraStat (3-D Matrix, Tokyo, Japan) is an absorbent localized hemostatic agent that uses self-assembling peptide technology. In this multicenter pilot study, we evaluated the efficacy and safety of endoscopic hemostasis using PuraStat in patients with colonic diverticular bleeding (CDB).</div></div><div><h3>Methods</h3><div>This study involved patients who had CDB with stigmata of recent hemorrhage (SRH) and underwent endoscopic hemostasis with PuraStat monotherapy or combination therapy comprising PuraStat with endoscopic band ligation (EBL) or clipping (group A). Treatment outcomes and adverse events were assessed and compared with those of a previous cohort who underwent endoscopic hemostasis without PuraStat for CDB with SRH (group B). Factors associated with the reduction of recurrent bleeding were subsequently investigated.</div></div><div><h3>Results</h3><div>PuraStat was used in 25 patients with CDB. The mean patient age was 70.8 years, 13 (52.0%) were men, and the most frequent bleeding sites were in the ascending colon (15 patients [60.0%]). The success rate of endoscopic hemostasis was 100% (25/25); 2 patients were treated with PuraStat monotherapy and 23 with combination therapy (EBL, 13 patients; clipping, 10 patients). The success rates were comparable between groups A and B (100% vs 96.4%, <em>P</em> = 1.000). The rate of recurrent bleeding within 30 days was significantly lower in group A than in group B (4.0% vs 20.9%, <em>P</em> = .047). Multivariate analyses revealed that the addition of PuraStat was associated with the reduced risk of recurrent bleeding (odds ratio, .11; 95% confidence interval, .01-.95; <em>P</em> = .045).</div></div><div><h3>Conclusions</h3><div>PuraStat can be easily added to conventional hemostatic methods for CDB, which could lower the risk of recurrent bleeding. (Clinical trial registration number: UMIN000053065.)</div></div>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 4","pages":"Pages 894-902"},"PeriodicalIF":6.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hsuan-Wei Chen MD, Yu-Ting Kuo MD, MSc, Kuo-Feng Hsu MD, PhD, Po-Da Chen MD, PhD, Hsiu-Po Wang MD
{"title":"Rescue laparoscopy-assisted repositioning of a misdeployed metal stent in the peritoneum after EUS-guided hepaticogastrostomy (with video)","authors":"Hsuan-Wei Chen MD, Yu-Ting Kuo MD, MSc, Kuo-Feng Hsu MD, PhD, Po-Da Chen MD, PhD, Hsiu-Po Wang MD","doi":"10.1016/j.gie.2024.11.041","DOIUrl":"10.1016/j.gie.2024.11.041","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 4","pages":"Pages 909-911"},"PeriodicalIF":6.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dechun Wang BMed, Ruobing Li BMed, Xiaohong Li BMed, Fumei Yang BMed, Suyuan Zhang MMed, Xiangao Wang BMed, Rong Zhu MD
{"title":"A rare atypical idiopathic mesenteric phlebosclerosis characterized by widespread submucosal bulges of small bowel and colon: first report","authors":"Dechun Wang BMed, Ruobing Li BMed, Xiaohong Li BMed, Fumei Yang BMed, Suyuan Zhang MMed, Xiangao Wang BMed, Rong Zhu MD","doi":"10.1016/j.gie.2024.11.034","DOIUrl":"10.1016/j.gie.2024.11.034","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 4","pages":"Pages 915-917"},"PeriodicalIF":6.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Manuela Estevinho MD , Mara Sarmento Costa MD , Rita Franco MD , Inês Pestana MD , Pedro Marílio Cardoso MD , Sara Archer MD , Maria Inês Canha MD , João Correia MD , Pedro Mesquita MD , Lídia Roque Ramos MD , Adélia Rodrigues MD , Catarina Gomes MD , Sandra Lopes MD , Rolando Pinho MD
{"title":"Preparation Regimens to Improve Capsule Endoscopy Visualization and Diagnostic Yield (PrepRICE): a multicenter randomized trial","authors":"Maria Manuela Estevinho MD , Mara Sarmento Costa MD , Rita Franco MD , Inês Pestana MD , Pedro Marílio Cardoso MD , Sara Archer MD , Maria Inês Canha MD , João Correia MD , Pedro Mesquita MD , Lídia Roque Ramos MD , Adélia Rodrigues MD , Catarina Gomes MD , Sandra Lopes MD , Rolando Pinho MD","doi":"10.1016/j.gie.2024.07.012","DOIUrl":"10.1016/j.gie.2024.07.012","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Current guidelines recommend bowel preparation before small-bowel capsule endoscopy (SBCE). However, the optimal protocol is yet to be defined. To determine the best timing for preparation in SBCE, we compared small-bowel visualization quality (SBVQ), diagnostic yield (DY), and patient-reported outcomes across 4 purgative regimens.</div></div><div><h3>Methods</h3><div>In this prospective, randomized (1:1:1:1), multicenter study, patients with suspected small-bowel bleeding were randomized into 4 arms: G1 (1 L of polyethylene glycol + ascorbic acid [Moviprep, Norgine, Amsterdam, The Netherlands] the night before SBCE), G2 (1 L in the morning up to 2 hours before SBCE), G3 (0.5 L up to 2 hours before SBCE + 0.5 L after the capsule reached the duodenum), and G4 (1 L after the capsule reached the duodenum). To assess DY, lesions were categorized as having high (P2) or low (P0 or P1) bleeding potential. SBVQ was assessed using the Brotz score. Transit times were measured, and patient tolerability was scored from 0 to 5, with higher scores indicating better tolerability.</div></div><div><h3>Results</h3><div>A total of 387 patients were included, 59% female and with a median age of 73 years (interquartile range, 23). The examination completion rate was lower in G1 (90%, <em>P</em> < .001). Small-bowel transit time was shorter for patients receiving purgative during SBCE (G3 and G4, <em>P</em> = .001). SBVQ was better in patients receiving purgative after reaching the small bowel (<em>P</em> < .001): a median of 7 for G1, 8 for G2, and 9 for G3 and G4. The overall DY of patients receiving intraprocedure purgatives (G3 + G4) was superior (42.7 vs 31.3%, <em>P</em> = .02); significant differences were found in the second and third terciles. Likewise, G3 and G4 had higher angioectasia detection (<em>P</em> = .04). Patients’ satisfaction was significantly superior for G4 (median, 4 points; interquartile range, 1).</div></div><div><h3>Conclusions</h3><div>The group that received the bowel preparation the night before SBCE had poorer outcomes. Intraprocedure purgative regimens reduced SBTT, enhanced visualization, improved DY, and increased angioectasia detection. G4 was the best-tolerated regimen.</div></div>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"101 4","pages":"Pages 856-865.e3"},"PeriodicalIF":6.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}