Gastrointestinal endoscopy最新文献

{"title":"Anatomical location of colorectal neoplasia in patients with positive stool test (multitarget stool DNA or fecal immunochemical test) results: data from the New Hampshire Colonoscopy Registry.","authors":"Joseph C Anderson, William M Hisey, Christina M Robinson, Paul J Limburg, Bonny L Kneedler, Lynn F Butterly","doi":"10.1016/j.gie.2025.08.043","DOIUrl":"10.1016/j.gie.2025.08.043","url":null,"abstract":"<p><strong>Background and aims: </strong>Data comparing the location of polyp yield in patients with positive stool test results can aid screening test selection. We conducted a cross-sectional analysis of New Hampshire Colonoscopy Registry data to compare the location, left versus right side of the colon, of neoplasia detected on colonoscopy after a multitarget stool DNA (mt-sDNA) test or a fecal immunochemical test (FIT), compared with a reference group undergoing colonoscopy without a stool test.</p><p><strong>Methods: </strong>Our outcomes were advanced lesions (adenomas and/or serrated polyps, including cancer), advanced adenomas, or advanced serrated polyps stratified by location. We examined the prevalence of left- versus right-sided lesions across 3 cohorts.</p><p><strong>Results: </strong>As compared to colonoscopy (n = 68,645), both FIT+ (n = 584) and mt-sDNA+ (n = 1176) patients had higher proportions of advanced lesions and advanced adenomas on both sides of the colon (P < .001). Mt-sDNA+ patients had significantly higher risks for right-sided advanced serrated polyps (odds ratio [OR] = 3.21; 95% confidence interval [CI], 2.67-3.85; colonoscopy [reference]) and right-sided advanced lesions (OR = 3.13; 95% CI, 2.66-3.68; colonoscopy [reference]) as compared to FIT+ (advanced serrated polyps: OR = 1.38; 95% CI, 0.99-1.99 and advanced lesions: OR = 1.84; 95% CI, 1.43-2.37) or colonoscopy (reference). In our main analysis, the colonoscopy-only group had significantly higher odds of each outcome on the right side than the left side; in comparison, the odds for FIT+ and mt-sDNA+ patients were more evenly distributed throughout the colon.</p><p><strong>Conclusions: </strong>Our data suggest that FIT+ tests are associated with higher detection of both right- and left-sided advanced adenomas as compared to colonoscopy without a prior stool test. Furthermore, mt-sDNA+ patients had higher proportions of left- and right-sided advanced adenomas and advanced serrated polyps, particularly on the right side.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of self-assembling peptide in reducing bleeding after colorectal endoscopic submucosal dissection.","authors":"Takeshi Yamamura, Masanao Nakamura, Mio Hiramatsu, Genta Uchida, Keisaku Yamada, Takeshi Kuno, Keiko Maeda, Tsunaki Sawada, Eri Ishikawa, Takashi Hirose, Takuya Ishikawa, Kazuhiro Furukawa, Takashi Honda, Hiroki Kawashima","doi":"10.1016/j.gie.2025.08.042","DOIUrl":"10.1016/j.gie.2025.08.042","url":null,"abstract":"<p><strong>Background and aims: </strong>The newly developed self-assembling peptide (SAP) is expected to exert hemostatic effects on the gastrointestinal tract and promote ulcer healing. However, its efficacy in preventing postprocedural hemorrhage after colorectal endoscopic submucosal dissection (ESD) remains uncertain. This study aimed to determine whether SAP could reduce hematochezia, including delayed bleeding (DB), and prevent its occurrence after colorectal ESD.</p><p><strong>Methods: </strong>This multicenter retrospective study included 1597 patients with 1654 colorectal ESD-related lesions treated between January 2017 and July 2024. Initially, 1419 lesions were analyzed and categorized into non-SAP and SAP groups. Subsequently, the differences between lesions with and without postprocedural hematochezia and DB were explored. Factors associated with hematochezia and DB were examined using univariate and multivariate logistic regression analyses.</p><p><strong>Results: </strong>A total of 719 and 700 lesions were assigned to the non-SAP and SAP groups, respectively. The use of SAP was associated with a significant reduction in hematochezia. In addition, SAP significantly reduced DB. SAP was identified as a significant factor in the prevention of hematochezia and DB after colorectal ESD.</p><p><strong>Conclusions: </strong>The application of SAP significantly reduced the occurrence of hematochezia and DB after colorectal ESD. Furthermore, SAP was a significant factor associated with the reduction of hematochezia and DB. Therefore, SAP may be appropriate for the prevention of post-ESD bleeding in the colon.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response.","authors":"Kyong Joo Lee, Se Woo Park","doi":"10.1016/j.gie.2025.07.036","DOIUrl":"https://doi.org/10.1016/j.gie.2025.07.036","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on the Multicenter prospective study of a novel spiral-designed plastic stent in malignant hilar biliary obstruction: suggestions for evidence optimization.","authors":"Meng-Yuan Shen, Ze-Jiong Li, Jian-Nong Wu","doi":"10.1016/j.gie.2025.06.050","DOIUrl":"https://doi.org/10.1016/j.gie.2025.06.050","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conservative management of dislodged endoclip in the appendix.","authors":"Ho Yu Ng, Justin Christopher Ng, Ka Shing Cheung","doi":"10.1016/j.gie.2025.08.040","DOIUrl":"10.1016/j.gie.2025.08.040","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best of endoscopic retrograde cholangiopancreatography articles 2025","authors":"Douglas G. Adler MD, FACG, AGAF, FASGE","doi":"10.1016/j.gie.2025.07.018","DOIUrl":"10.1016/j.gie.2025.07.018","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"102 5","pages":"Pages 636-638"},"PeriodicalIF":7.5,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best of: Artificial intelligence in GI endoscopy.","authors":"Michael B Wallace","doi":"10.1016/j.gie.2025.08.038","DOIUrl":"10.1016/j.gie.2025.08.038","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of submucosal lesion of rectum: an unexpected isolated muscularis propria layer rectal endometriosis.","authors":"Feng Xiong, Shenggang Zhan, Wenbiao Chen, Yiteng Meng","doi":"10.1016/j.gie.2025.08.037","DOIUrl":"10.1016/j.gie.2025.08.037","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Random Neo-Squamous and Cardia Biopsies During Surveillance After Dysplastic Barrett's Eradication: A Prospective Single- Center Study.","authors":"Aman Yadav, Sunil Gupta, Shwan Karim, Xuan Banh, Jennifer Borowsky, Caroline Cooper, Ian Hughes, Luke F Hourigan, Alexander Huelsen","doi":"10.1016/j.gie.2025.08.033","DOIUrl":"https://doi.org/10.1016/j.gie.2025.08.033","url":null,"abstract":"<p><strong>Background and aims: </strong>Surveillance post complete eradication of dysplastic Barrett's esophagus (BE) is important given the risk of recurrent intestinal metaplasia and neoplasia, however the optimal surveillance strategy remains unclear. This study aims to ascertain the yield of random biopsies of the neo-squamous epithelium (NE) and gastric cardia for detecting dysplasia.</p><p><strong>Methods: </strong>In this prospective single-center study, patients undergoing post-endoscopic eradication therapy (EET) surveillance for dysplastic BE were included. High-definition white light, narrow-band, and near-focus imaging were used for esophageal assessment. Targeted biopsies were performed on visible abnormalities, followed by six random cardia biopsies and four-quadrant NE biopsies at 1 cm intervals.</p><p><strong>Results: </strong>Seventy-one patients underwent 119 surveillance endoscopies after complete eradication of intestinal metaplasia (CEIM), yielding 2,892 biopsies (66 targeted, 714 random cardia, 2,112 NE). Targeted biopsies detected IM in 15.2% (10/66) and dysplasia in 3% (2/66) of biopsies, leading to further treatment in 8 patients. In contrast, IM was detected in 2.4% (17/714) of random cardia biopsies and 0.4% (9/2112) of random NE biopsies. No dysplasia was detected via random cardia or NE biopsies. The total cost to detect one case of IM via random biopsies was $3,144, whereas the cost to detect one case of dysplasia using the random biopsy strategy exceeded $29,673.</p><p><strong>Conclusions: </strong>Targeted biopsies of the NE and gastric cardia are important in detecting early BE recurrence. Additional random NE and cardia biopsies provide no added benefit in dysplasia detection but incur unnecessary time and cost expenditures. We recommend targeted biopsies as the primary surveillance strategy post-CEIM and eliminating random biopsies in expert centers.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144950205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bowel Preparation Quality in Patients Using Glucagon-Like Peptide-1 Agonists: A Systematic Review and Meta-Analysis","authors":"Zohaib Ahmed MD, Amna Iqbal MD, Syeda Faiza Arif, Connor Campbell MS4, Jared Fehlman MD, David James Allen, Wade Lee Smith MSc, Basmah Khalil MD, Faisal Kamal MD, Umair Iqbal, Ali Nawras MD, Yaseen Alastal MD, Douglas G. Adler MD","doi":"10.1016/j.gie.2025.08.027","DOIUrl":"https://doi.org/10.1016/j.gie.2025.08.027","url":null,"abstract":"Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are now the mainstay treatment for many chronic conditions including diabetes mellitus, obesity, heart failure and chronic kidney disease. GLP-1 RAs may affect bowel preparation for a colonoscopy by modifying intestinal motility and gastric emptying. We conducted a systematic review and meta-analysis to investigate the impact of GLP-1 RA use on bowel preparation quality, measured by the Boston Bowel Preparation Scale (BBPS), and the frequency of inadequate preparation events.","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"15 1","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}