American Journal of Medicine and Medical Sciences最新文献_第5页

Oral Administration of Aqueous Leaf Extract of Ocimum Gratissimum Ameliorates Polyphagia, Polydipsia and Weight Loss in Streptozotocin-Induced Diabetic Rats 枸杞子叶水提物可改善链脲佐菌素诱导的糖尿病大鼠的多食、多饮和体重减轻

American Journal of Medicine and Medical Sciences Pub Date : 2012-05-09 DOI: 10.5923/J.AJMMS.20120203.04

D. U. Owo, N. Udokang, J. Udobang, C. Ekpenyong

{"title":"Oral Administration of Aqueous Leaf Extract of Ocimum Gratissimum Ameliorates Polyphagia, Polydipsia and Weight Loss in Streptozotocin-Induced Diabetic Rats","authors":"D. U. Owo, N. Udokang, J. Udobang, C. Ekpenyong","doi":"10.5923/J.AJMMS.20120203.04","DOIUrl":"https://doi.org/10.5923/J.AJMMS.20120203.04","url":null,"abstract":"The effects of oral administration of aqueous leaf extract of Ocimum gratissimum (OG) on food, water intake and weight changes in streptozotocin (STZ)-induced diabetic Albino Wistar rats was studied. Eighteen rats were randomly assigned into 3 groups of 6 rats each for control, diabetic (DM) and diabetic-treated (DMT) groups. Diabetes mellitus was induced in the test groups (DM and DMT) by a single dose of STZ (65 mg/kg, i.p.). The extract was administered per oral to the DMT group at a dose of 1500 mg/k body weight daily for 28 days. All the groups were fed normal rat chow and al- lowed water freely. The fasting blood glucose levels in the DM and DMT groups were higher (P<0.001) than the control group, with the DMT group lower (P<0.01) than the DM group. There was a significant (P<0.05) loss of body weight in the DM group compared to the control (P<0.01) and DMT (P<0.05) groups. There was an increase (P<0.01) in volume of wa- ter taken by the test groups compared to the control. The water intake in DMT group was lower (P<0.01) than the DM group. The food intake in the DM group was greater (P<0.001) than the control and DMT groups, with the later higher (P<0.05) than the control group. We therefore conclude that Ocimum gratissimum reduces blood sugar level in STZ-induced diabetic rats and alleviates the cardinal symptoms of diabetes mellitus namely; polydypsia, polyphagia and weight loss.","PeriodicalId":124628,"journal":{"name":"American Journal of Medicine and Medical Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125288528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 60

Effect of Ondansetron alone or in Combination with Dehydrobenzperidole and Dexamethasone on Discharge Time Following Gynecological Laparoscopy 昂丹司琼单用或联用脱氢苯哌啶多及地塞米松对妇科腹腔镜术后出院时间的影响

American Journal of Medicine and Medical Sciences Pub Date : 2012-05-09 DOI: 10.5923/J.AJMMS.20120203.03

H. Petersen, C. Hemmingsen

{"title":"Effect of Ondansetron alone or in Combination with Dehydrobenzperidole and Dexamethasone on Discharge Time Following Gynecological Laparoscopy","authors":"H. Petersen, C. Hemmingsen","doi":"10.5923/J.AJMMS.20120203.03","DOIUrl":"https://doi.org/10.5923/J.AJMMS.20120203.03","url":null,"abstract":"We aimed to examine a possible accelerated discharge time after gynecological laparoscopy when treated with a combination of ondansetron, dehydrobenzperidole and dexamethasone as compared to ondansetron alone. Sixty ASA 1-2 women were included in this prospective double-blind study and were randomised to either peroperative ondansetron 4 mg, dehydrobenzperidole 0.625 mg and dexamethasone 8 mg or to ondansetron 4 mg only. General anaesthesia was induced by fentanyl, propofol, mivacurium and maintained by sevoflurane in 50% oxygen. Patients were tracheal intubated and had a orogastric tube during the laparoscopy. The neuromuscular block was allowed to wear of without the use of neostigmine. In case of postoperative nausea and vomiting in the ondansetron only group, escape medication with dehydrobenzperidole and dexamethasone was given. The discharge criteria at the day surgery unit were fulfilled at 7h 45min (range 3h 10min - 24h 16min) after the end of surgery in the women treated with ondansetron only, but was accelerated to 5h 11min (range 3h 9min - 21h 8min) in the women having peroperative treatment with both ondansetron, dehydrobenzperidole and dexamethasone (p<0.01). Postoperative nausea and vomiting was evident in 4% at arrival at day surgery recovery after treatment with the triple combination, but in 16% in the patients treated with ondansetron alone (p<0.01). In conclusion, peroperative treatment with a combination of ondansetron, dehydrobenzperidole and dexamethasone allows a significantly accelerated discharge time after gynecological laparoscopy and causes a significantly reduced incidence of nausea and vomiting.","PeriodicalId":124628,"journal":{"name":"American Journal of Medicine and Medical Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126600905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation of Flipped Classroom Design in Transfusion Science Course 翻转课堂设计在输血学课程中的实施

American Journal of Medicine and Medical Sciences Pub Date : 1900-01-01 DOI: 10.5923/J.AJMMS.20190907.10

S. Shibeeb

引用次数: 0

New technologies in treatment of patients in the acute period of stroke 脑卒中急性期治疗的新技术

American Journal of Medicine and Medical Sciences Pub Date : 1900-01-01 DOI: 10.31838/ijpr/2020.12.02.0025

D. Khodjieva, D. Khaydarova, N. Khaydarov

引用次数: 0

Citrullus Colocynthis a Prospective Antimicrobial and Antifungal Agent 瓜蒌多糖是一种有前景的抗菌和抗真菌药物

American Journal of Medicine and Medical Sciences Pub Date : 1900-01-01 DOI: 10.5923/J.AJMMS.20190902.01

A. Aljabry, Ayat Ahmed Alrasheid, Elnur Ramadan

引用次数: 1

The Auditory Working Memory of 13-15-Year-Old Adolescents Using Water with Varying Fluoride Concentrations from Selected Public Primary Schools in North Kajiado Sub County 13-15岁青少年使用不同氟化物浓度饮用水的听觉工作记忆研究

American Journal of Medicine and Medical Sciences Pub Date : 1900-01-01 DOI: 10.5923/J.AJMMS.20180810.04

Benjamin Induswe, G. Opinya, L. Khasakhala, R. Owino

{"title":"The Auditory Working Memory of 13-15-Year-Old Adolescents Using Water with Varying Fluoride Concentrations from Selected Public Primary Schools in North Kajiado Sub County","authors":"Benjamin Induswe, G. Opinya, L. Khasakhala, R. Owino","doi":"10.5923/J.AJMMS.20180810.04","DOIUrl":"https://doi.org/10.5923/J.AJMMS.20180810.04","url":null,"abstract":"Water contributes significantly to the physiological functions in the in the human body. However, low fluoride doses have been reported to affect the central nervous system (CNS) without first causing the physical malformations of dental and skeletal fluorosis. Aims and objectives were to determine fluoride concentrations in water used by adolescents who were born and raised in North Kajiado and correlated it with their Auditory Working Memory Index (AWMI). The survey was cross-sectional and descriptive involving 269 school children aged 13-15 years. A purposeful sampling frame was used to select the schools. Fluoride in water was determined using the Fluoride Ion selective electrode. The AWM was assessed using the Wechsler intelligence scale for Children V (WISC-V) subtest. The mean auditory working index for the group was 111.5±22.6 while the boys had a mean AWMI of 111.46±22.37 and the girls 111.56±22.75. A comparison of the AWM of children from low (105.40±23.6) and high (99.52±23.2) fluoride schools and medium with high fluoride school had significant differences. The AWM for the children whose household water had low fluoride had higher AWMI 122.58±19.9 compared to those whose household had high fluoride in the with ANOVA F (2, 266) = 17.968, p≤.0001 and Tukey HSD for low and medium (m=-5.919, se=3.146, p=.145, low and high fluoride, (m=-18.559. se=3.124, p≤.001; medium and high (m=-12.640, se= 3.32, p≤.001 at 95% CL. In conclusion, low fluoride in the water seemed to enhance the AWM. However, the AWM declined with an increased in the fluoride concentration in water.","PeriodicalId":124628,"journal":{"name":"American Journal of Medicine and Medical Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114732372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Indeterminate Form of Chagas' Disease and Metabolic Syndrome: A Dangerous Combination 不明形式的恰加斯病和代谢综合征:危险的组合

American Journal of Medicine and Medical Sciences Pub Date : 1900-01-01 DOI: 10.5923/J.AJMMS.20130304.03

E. C. Navarro, Mariana Abreu, Francilene Capel Tavares, J. Corrente, C. Arruda, P. C. Pereira

引用次数: 10