Özge Ünlütürk, Arif Garbioğlu, Muhammed Emin Gökşen, Murat Nihat Arslan
{"title":"Comparison of autopsy and stereomicroscope findings in the examination of hyoid bone fractures.","authors":"Özge Ünlütürk, Arif Garbioğlu, Muhammed Emin Gökşen, Murat Nihat Arslan","doi":"10.1007/s12024-026-01181-1","DOIUrl":"10.1007/s12024-026-01181-1","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"886-895"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serial determination of caffeine and active metabolites in a case of severe caffeine poisoning causing recurrent cardiac arrest after hemodialysis: a case report.","authors":"Saeko Kohara, Yoshito Kamijo, Ryoko Kyan, Hiroko Abe, Taiki Yamataka","doi":"10.1007/s12024-026-01193-x","DOIUrl":"10.1007/s12024-026-01193-x","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1079-1082"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147456810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Jane Heathfield, Lisa Malan, Chandra Finaughty, Calvin Gerald Mole, Victoria Elaine Gibbon
{"title":"A retrospective case review of decedents recovered from aquatic environments in Cape Town, South Africa.","authors":"Laura Jane Heathfield, Lisa Malan, Chandra Finaughty, Calvin Gerald Mole, Victoria Elaine Gibbon","doi":"10.1007/s12024-026-01229-2","DOIUrl":"10.1007/s12024-026-01229-2","url":null,"abstract":"<p><p>The identification of deceased individuals is a mandated component of medico-legal death investigations. Due to the unique taphonomic circumstances of decedents retrieved from aquatic environments, identification is often challenging. This study retrospectively examined 289 cases of deceased individuals recovered from aquatic environments that were admitted to Salt River Mortuary in Cape Town between January 2017 and December 2021. Case report data and associated documented information were analysed to evaluate reported post-mortem submersion intervals (PMSI), recovered body segments, and identification methods to inform future procedural improvements and prevention strategies. Findings indicated that 48.4% (140/289) of cases were recovered from the ocean. Overall, 33.2% (96/289) of cases were admitted to the mortuary with unknown identity, among these, 25.0% (24/96) were not identified after the medico legal investigation. The presumed identities of a further two cases were unconfirmed following post-mortem investigation, resulting in 9.0% (26/289) decedents remaining unidentified. Most unidentified decedents were recovered from the ocean 69.2% (18/26). Samples for DNA profiling were collected in 28.4% (82/289) cases and were successfully used in identification for 32.9% (27/82) cases. The average post-mortem submersion interval was less than two weeks for 51.2% (148/289) of cases but was undetermined for 47.8% (138/289) cases. The taphonomic environment of aquatic cases results in rapid and extensive breakdown of biological tissues leading to reduced rates of identification, which requires scientific focus and attention. To enhance identification rates for aquatic cases, further research into methodological and technological adjustments are required. In particular exploring alternatives to visual identification through use of DNA analyses and a better understanding of taphonomic processes in these aquatic environments may improve medico-legal death investigations.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1037-1050"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148041764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvia Farkašová Iannaccone, Alžbeta Ginelliová, Viktória Briškárová, Daniel Farkaš
{"title":"Auto-brewery syndrome with Candida-associated gastric ulcers in a severely cachectic child.","authors":"Silvia Farkašová Iannaccone, Alžbeta Ginelliová, Viktória Briškárová, Daniel Farkaš","doi":"10.1007/s12024-025-01170-w","DOIUrl":"10.1007/s12024-025-01170-w","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1099-1105"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cecilie Bækgård, Lars Andresen, Marie Høy Hansen, Henrik Elvang Jensen, Kristine Freude, Kristiane Barington
{"title":"A multidisciplinary approach for the study of age-dependent expression patterns in porcine experimental wounds.","authors":"Cecilie Bækgård, Lars Andresen, Marie Høy Hansen, Henrik Elvang Jensen, Kristine Freude, Kristiane Barington","doi":"10.1007/s12024-026-01183-z","DOIUrl":"10.1007/s12024-026-01183-z","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1139-1150"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation between BAC and abdominal muscle alcohol concentration: a promising parachute matrix in cases of severe injury.","authors":"Pascale Basilicata, Angela Simonelli, Mariagrazia Marisei, Maurizio Municinò, Rossella Guadagni, Angela Silvestre, Maria Pieri","doi":"10.1007/s12024-026-01212-x","DOIUrl":"10.1007/s12024-026-01212-x","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1083-1090"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Critical appraisal on \"automatic measuring of coronary atherosclerosis from medicolegal autopsy photographs based on deep learning techniques\".","authors":"Mihir Manuja","doi":"10.1007/s12024-025-01111-7","DOIUrl":"10.1007/s12024-025-01111-7","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"995-996"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145408552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatal gelsemium alkaloid poisoning versus cardiovascular cause in a sudden death: a forensic case report.","authors":"Guodong Qin, Pengfei Zhao","doi":"10.1007/s12024-026-01180-2","DOIUrl":"10.1007/s12024-026-01180-2","url":null,"abstract":"<p><p>Gelsemium alkaloids, such as gelsemine and koumine, are highly toxic compounds that can induce rapid respiratory and cardiovascular failure. Their clinical manifestations-dizziness, ptosis, and sudden collapse-closely resemble those of acute myocardial infarction, presenting diagnostic challenges in forensic practice, especially in distinguishing between poisoning and cardiovascular events. We describe a sudden death in a middle-aged male following a restaurant meal. The decedent developed acute dizziness and eyelid drooping shortly after ingestion and died within hours despite resuscitation. Autopsy revealed pulmonary edema, systemic congestion, and coronary atherosclerosis with ischemic changes, but without acute infarction. Toxicological analyses identified gelsemine and koumine in meal remnants and biological samples, which were confirmed by LC-MS/MS with validated parameters. The concentrations detected were within reported toxic ranges, supporting a fatal exposure. On the balance of evidence, the death was most consistent with poisoning from Gelsemium alkaloids, rather than primary cardiac disease. This case emphasizes the importance of integrating toxicological confirmation with pathological findings to distinguish poisoning from cardiovascular causes in sudden deaths.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"857-861"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146141710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Ambrosi, Federica Amirante, Simona Nicolì, Andrea Marzullo, Giuseppe Ingravallo, Davide Ferorelli, Biagio Solarino, Gianmarco Argentiero
{"title":"Digital pathology in forensic science: a systematic review of the literature.","authors":"Laura Ambrosi, Federica Amirante, Simona Nicolì, Andrea Marzullo, Giuseppe Ingravallo, Davide Ferorelli, Biagio Solarino, Gianmarco Argentiero","doi":"10.1007/s12024-025-01146-w","DOIUrl":"10.1007/s12024-025-01146-w","url":null,"abstract":"<p><strong>Background: </strong>Digital pathology (DP) and whole-slide imaging (WSI) are increasingly utilized in clinical pathology; however, their role in forensic medicine remains less defined, as evidentiary standards demand robust validation, auditability, and a chain of custody.</p><p><strong>Methods: </strong>We conducted a systematic review of PubMed, Scopus, and Web of Science for studies that applied DP and WSI to forensic, autopsy, or postmortem contexts, with eligibility requiring peer-reviewed human studies that reported methods and outcomes. Data were charted for study design, tissue, devices/software, and outcomes (diagnostic agreement, quantitative metrics, validation/quality assurance (QA)).</p><p><strong>Results: </strong>The search retrieved 361 records; after screening and full-text assessment, 21 studies were selected for inclusion. Fifteen studies primarily advanced diagnostic knowledge using postmortem material (e.g., quantitative neuropathology and organ-specific morphometry), while five had direct forensic aims (casework validation or core forensic tests).</p><p><strong>Conclusions: </strong>The review highlights that DP is technically ready for medico-legal workflows; however, its use remains low compared to other clinical settings. Adoption in forensics should centre on CAP-style, use-case-specific validation, traceable/auditable pipelines (including hashing, logs, and tile-linked overlays), stain/colour governance, and external robustness testing. Under these conditions, DP can deliver reproducible, transparent, and court-defensible evidence across forensic practice.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1121-1136"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145752060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}