Forensic Science, Medicine and Pathology最新文献_第2页

Fifty shades of green and blue: autopsy findings after administration of xenobiotics. 五十度的绿色和蓝色：服用异种生物制剂后的尸检结果。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-30 DOI: 10.1007/s12024-024-00903-7

J Baumgarten, I Greb, F Holz, C Nieß, S Petzel-Witt, Christoph G Birngruber

{"title":"Fifty shades of green and blue: autopsy findings after administration of xenobiotics.","authors":"J Baumgarten, I Greb, F Holz, C Nieß, S Petzel-Witt, Christoph G Birngruber","doi":"10.1007/s12024-024-00903-7","DOIUrl":"https://doi.org/10.1007/s12024-024-00903-7","url":null,"abstract":"Unusual findings during an autopsy may come from peculiarities in the position, shape, size, weight, consistency, smell or color of organs. The following study was triggered by an autopsy case in which an unusual blue-green discoloration of organs, which changed during the autopsy, was noticed. A review of the local autopsy database, selected cases including the antemortem clinical documentation and the literature has been performed to clarify the etiology of these conspicuous discolorations and to evaluate their diagnostic value. The study showed that certain xenobiotics may lead to such discoloration. After systemic administration of methylene blue, darkening blue-green discoloration of organs, especially the brain and heart, can be observed. In addition, the systemic administration of toluidine blue also appears to be capable of causing such discoloration. Beyond that, drugs (like Rohypnol®) or other foreign substances (like detergents) containing warning colors, i.e. indigocarmin (E132) or Brilliant Blue FCF (E133) may cause discolorations of the upper gastrointestinal tract or the urinary bladder respectively. A blue-green, possibly darkening discoloration of organs during autopsy may point towards an antemortem administration of certain xenobiotics. The affected organs give an indication of the possible route of application and the type of substance. A differentiated interpretation of the etiology of such conspicuous discolorations at autopsy should only be made considering the (medical) history and, if necessary, complementary (toxicological) examinations.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual analysis of postmortem interval estimation trends and collaborative networks: a 15-year study (2006-2020). 死后间隔估计趋势和协作网络的可视化分析：一项为期 15 年的研究（2006-2020 年）。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-30 DOI: 10.1007/s12024-024-00908-2

Chuangyan Zhai

{"title":"Visual analysis of postmortem interval estimation trends and collaborative networks: a 15-year study (2006-2020).","authors":"Chuangyan Zhai","doi":"10.1007/s12024-024-00908-2","DOIUrl":"https://doi.org/10.1007/s12024-024-00908-2","url":null,"abstract":"Utilizing a visual analysis of the literature on postmortem interval (PMI) estimation indexed by Web of Science (WOS), this study investigates developmental trends and research hot points across each 5-year period from 2006 to 2020. Additionally, collaborative efforts among authors, countries, and institutions were examined. Research hot points, high-frequency keywords, authors, countries and institutions in relevant papers were analyzed using CiteSpace.5.7.R2 information visualization analysis software over the past 15 years. The literature related to PMI estimation has witnessed consistent growth over time. In the keyword co-occurrence network, several impactful terms stand out, including blowfly, mitochondrial DNA, and emerging concepts like virtual autopsy. Technological advancements, such as RNA stability analysis and virtual autopsy tools, have played a pivotal role in shaping the direction of PMI research. Scientific research institutions dominate the high-frequency affiliations within the institutional cooperative network. Additionally, the country cooperative network exhibits a trend of co-occurrence and multi-clustering. As science and technology continue to advance, traditional PMI estimation methods mature while novel interdisciplinary approaches drive innovation. By identifying emerging trends and research hotspots, this study provides a roadmap for future investigations, guiding researchers toward new opportunities in PMI estimation.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The art of peer reviewing. 同行评审的艺术

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-29 DOI: 10.1007/s12024-024-00905-5

Roger W Byard

引用次数: 0

Development of conductive fingermarks for forensic applications. 开发用于法医应用的导电指印。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-24 DOI: 10.1007/s12024-024-00898-1

Niamh E Richards, Andrew Langley, Laura J Vera Stimpson

引用次数: 0

Page kidney in a case of polyarteritis nodosa. 页码结节性多动脉炎病例中的肾脏。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-24 DOI: 10.1007/s12024-024-00904-6

Tuba Demirci Yıldırım

引用次数: 0

The other side of the paper as the evidence: impacts of fingermark development reagents on fingermark development and cocaine amount in cocaine-impregnated paper. 纸的另一面是证据：指痕显影试剂对可卡因浸渍纸中指痕显影和可卡因含量的影响。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-17 DOI: 10.1007/s12024-024-00897-2

Yakup Gulekci, Fatma Cavus Yonar, Pınar Efeoglu Ozseker, İsmail Ethem Gören, Nebile Daglioglu

{"title":"The other side of the paper as the evidence: impacts of fingermark development reagents on fingermark development and cocaine amount in cocaine-impregnated paper.","authors":"Yakup Gulekci, Fatma Cavus Yonar, Pınar Efeoglu Ozseker, İsmail Ethem Gören, Nebile Daglioglu","doi":"10.1007/s12024-024-00897-2","DOIUrl":"https://doi.org/10.1007/s12024-024-00897-2","url":null,"abstract":"Despite various preventative measures, cocaine smuggling is still a major problem worldwide. A recent method of smuggling is the transportation of cocaine with various chemicals or with impregnated materials such as cloth and paper. This study aims to examine the change in the amount of cocaine on the paper surface and attempts to decide the best fingermark development method in the case of smuggling trafficking in the form of impregnated paper with the least effect on the cocaine concentration on the paper. The papers (n = 6 + 1) were prepared for each fingermark development method, including a blank paper, were dipped into a working solution prepared by dissolving 0.38 mg cocaine in 500 mL methanol. Fingermarks were developed by applying various chemicals, including Iodine vapor, 1,2-Indandione, DFO (1,8-diazafluoren-9-one), ThermaNin, 5-MTN (5-methylthioninhydrin), and silver nitrate chemicals and Ninhydrin, which is the most commonly used reagent for visualizing latent prints, particularly on paper surfaces. Also, the natural fingermarks of four different donors, two women and two men between 20 and 50 years of age, were used to compare with the presence of cocaine. Different from others, this study examined the application of DFO and 1,2-Indandione as alternatives to other chemicals and revealed that it is possible to identify cocaine using these methods. The order of success was Ninhydrin > DFO > 1,2-Indandione > ThermaNin > Iodine vapor = 5-MTN. To the best of our knowledge, the current study is the first to investigate fingermark identification methods along with the amounts of cocaine on cocaine-impregnated papers.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Air embolism during unsuccessful transcatheter closure of secundum atrial septal defect in a patient with an undetected left-sided inferior vena cava. 一名未检测到左侧下腔静脉的患者在经导管关闭房间隔缺损不成功的过程中发生空气栓塞。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-17 DOI: 10.1007/s12024-024-00902-8

Silvia Farkašová Iannaccone, Alžbeta Ginelliová, Janka Vecanová, Daniel Farkaš

{"title":"Air embolism during unsuccessful transcatheter closure of secundum atrial septal defect in a patient with an undetected left-sided inferior vena cava.","authors":"Silvia Farkašová Iannaccone, Alžbeta Ginelliová, Janka Vecanová, Daniel Farkaš","doi":"10.1007/s12024-024-00902-8","DOIUrl":"https://doi.org/10.1007/s12024-024-00902-8","url":null,"abstract":"A 46-year-old man with a history of secundum atrial septal defect and interstitial lung disease was admitted to the hospital for a planned transcatheter closure of the atrial septal defect. Following multiple failed attempts to place a right femoral vein catheter, the procedure was aborted. Another attempt was made to the left femoral vein, but that attempt was complicated by an unfamiliar resistance. Even though resistance was met during insertion, the catheter was further inserted until a position in the inferior vena cava above the liver was obtained at fluoroscopy. Simultaneously, the patient became unresponsive. The procedure was immediately aborted and the atrial septal defect closure was not completed. Air embolism to the heart and brain was detected using echocardiography and computed tomography. The patient died 15 days after the procedure. Death was attributed to severe cerebral edema due to air embolism. The autopsy revealed a left-sided inferior vena cava. This case report demonstrates that unexpected congenital vascular anomalies complicating a routine transcatheter closure of the atrial septal defect can result in a fatal outcome.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidental detection of aluminum phosphide in abdominal subcutaneous fat- a rare reporting of chemical analysis findings in poisoning cases. 在腹部皮下脂肪中意外检测到磷化铝--中毒病例中罕见的化学分析结果报告。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-10 DOI: 10.1007/s12024-024-00899-0

Arijit Datta, Dhara Goswami, Srushti Shukla, Darshan Galoria, Pradip Rana, Arpan Kumar Pan

{"title":"Incidental detection of aluminum phosphide in abdominal subcutaneous fat- a rare reporting of chemical analysis findings in poisoning cases.","authors":"Arijit Datta, Dhara Goswami, Srushti Shukla, Darshan Galoria, Pradip Rana, Arpan Kumar Pan","doi":"10.1007/s12024-024-00899-0","DOIUrl":"https://doi.org/10.1007/s12024-024-00899-0","url":null,"abstract":"Aluminum phosphide (AlP) poses a significant health challenge in developing countries, primarily because of its accessibility to the unregulated market and the absence of specific antidotes. Although chemical analysis of routine viscera can provide valuable information regarding the type of poison present in the body during poisoning incidents, numerous factors can alter the test results of chemical analysis, such as decomposition changes, postmortem redistribution, and the chemical nature of drugs. Analytical methods are frequently impeded by the interference caused by coextracted putrefactive compounds, which can mask or alter the detection of drugs. This series of three cases is particularly noteworthy because it involves the postmortem detection of AlP in the abdominal subcutaneous fat of the deceased, a previously unreported occurrence. In the first case, the body showed findings of late postmortem changes, with stomach mucosa being congested and hemorrhagic, along with routine viscera, and abdominal subcutaneous fat was sent for toxicological analysis. To confirm these findings, in two further cases of suspected AlP poisoning, subcutaneous fat was sent along with routine viscera. Stomach mucosa in the other two cases showed findings similar to those in the first. In the third case, black paste-like material was noted as stomach content. All the cases revealed the presence of AlP in routine viscera samples and abdominal subcutaneous fat on gas chromatography-mass spectrometry (GC‒MS) analysis. Therefore, abdominal fat can serve as a suitable sample for toxicological analysis to identify the presence of AlP, even in cases with advanced putrefactive changes.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iatrogenic needle penetrating injury of cervical spinal cord: a case of fatal therapeutic complication. 先天性针头穿透颈脊髓损伤：一例致命的治疗并发症。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-09 DOI: 10.1007/s12024-024-00886-5

Fabio A Tironi, Michael S Pollanen

{"title":"Iatrogenic needle penetrating injury of cervical spinal cord: a case of fatal therapeutic complication.","authors":"Fabio A Tironi, Michael S Pollanen","doi":"10.1007/s12024-024-00886-5","DOIUrl":"https://doi.org/10.1007/s12024-024-00886-5","url":null,"abstract":"A 52-year-old woman with of neck pain underwent percutaneous neck injection of local anesthetic and a corticosteroid without image guidance. She collapsed asystolic during the procedure was resuscitated and then died after 2 weeks in the intensive care unit with hypoxic encephalopathy. Complete postmortem examination included additional posterior neck dissection and cervical spinal cord removal with intact dura mater. The entire cervical spinal cord with the dura and leptomeninges was embedded in an oriented sequence of several paraffin blocks. Serial sections of each selected blocks were then studied to locate a putative puncture site. Serial sections from the third and fourth cervical levels (C3-C4) were stained with luxol fast blue-hematoxylin-eosin, iron stain, trichrome stain, and immunostained for b-amyloid precursor protein, and CD68. Histological examination revealed a linear needle track with a subacute healing reaction. The path included the dorsal spinal dura, arachnoid, and the left dorsal column. Clinicopathological correlation and the cause of death are discussed. Careful planning, dissection, sampling, and oriented serial sectioning with immunostaining were key points to document the injuries and understand this case.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Arc-like curvilinear bullet pathways along inner surface of skull - two cases. 沿着头骨内表面的弧形曲线子弹路径--两个案例。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-10-07 DOI: 10.1007/s12024-024-00901-9

Keenan Boulnemour, Joseph A Prahlow

引用次数: 0