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Steroid use and lipid abnormalities in children: assessing the risk in chronic disease management. 儿童类固醇使用和脂质异常：评估慢性疾病管理的风险
Folia medica Pub Date : 2026-04-16 DOI: 10.3897/folmed.68.e171187
Siska Mayasari Lubis, Melda Deliana, Megan Quinka, Shofiyya Imtiyaz
{"title":"Steroid use and lipid abnormalities in children: assessing the risk in chronic disease management.","authors":"Siska Mayasari Lubis, Melda Deliana, Megan Quinka, Shofiyya Imtiyaz","doi":"10.3897/folmed.68.e171187","DOIUrl":"10.3897/folmed.68.e171187","url":null,"abstract":"<p><strong>Introduction: </strong>Although steroid-induced dyslipidemia is well-documented in adults, its impact on children remains underexplored. Given the long-term cardiovascular risks associated with dyslipidemia, understanding its link with steroid use in children is crucial.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation patterns of CEA, CA19-9, CA72-4, CA125, CA15-3, and PIVKA-II in malignant pleural effusions: overlap and distinction across tumor biology. 恶性胸腔积液中CEA、CA19-9、CA72-4、CA125、CA15-3和PIVKA-II的相关模式：肿瘤生物学上的重叠和区别
Folia medica Pub Date : 2026-04-16 DOI: 10.3897/folmed.68.e172308
Vladimir Aleksiev, Daniel Markov, Kristian Bechev, Boyko Yavorov, Filip Shterev
{"title":"Correlation patterns of CEA, CA19-9, CA72-4, CA125, CA15-3, and PIVKA-II in malignant pleural effusions: overlap and distinction across tumor biology.","authors":"Vladimir Aleksiev, Daniel Markov, Kristian Bechev, Boyko Yavorov, Filip Shterev","doi":"10.3897/folmed.68.e172308","DOIUrl":"https://doi.org/10.3897/folmed.68.e172308","url":null,"abstract":"<p><strong>Introduction: </strong>Malignant pleural effusions (MPEs) are a frequent complication of cancer, causing significant morbidity and representing a major diagnostic challenge. Tumor markers in pleural fluid have been studied, but their interrelationships remain poorly understood.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of dentists' knowledge of oral manifestations of Corynebacterium diphtheriae infection: a questionnaire-based survey. 评估牙医对白喉棒状杆菌感染口腔表现的知识：一项基于问卷的调查。
Folia medica Pub Date : 2026-04-16 DOI: 10.3897/folmed.68.e171679
Veselina Kondeva, Velina Stoeva, Rumyana Stoyanova
{"title":"Assessment of dentists' knowledge of oral manifestations of <i>Corynebacterium diphtheriae</i> infection: a questionnaire-based survey.","authors":"Veselina Kondeva, Velina Stoeva, Rumyana Stoyanova","doi":"10.3897/folmed.68.e171679","DOIUrl":"https://doi.org/10.3897/folmed.68.e171679","url":null,"abstract":"<p><strong>Introduction: </strong>Diphtheria is a severe airborne bacterial anthroponosis characterized by high mortality rates and high prevalence in many geographical regions. It presents with a distinctive appearance in the oral cavity, marked by extensive pseudomembranes, and dentists may frequently be the first healthcare providers to diagnose it.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between smoking burden and one-year mortality in ST-elevation and non-ST-elevation myocardial infarction: insights from a regional cohort. st段抬高和非st段抬高心肌梗死患者吸烟负担与一年死亡率之间的关系：来自区域队列的见解
Folia medica Pub Date : 2026-04-16 DOI: 10.3897/folmed.68.e174430
Parisa Janjani, Sayeh Motevaseli, Nader Asgari, Mohammad Rouzbahani, Hosna Janjani, Atiyeh Asadmobini, Nahid Salehi
{"title":"Association between smoking burden and one-year mortality in ST-elevation and non-ST-elevation myocardial infarction: insights from a regional cohort.","authors":"Parisa Janjani, Sayeh Motevaseli, Nader Asgari, Mohammad Rouzbahani, Hosna Janjani, Atiyeh Asadmobini, Nahid Salehi","doi":"10.3897/folmed.68.e174430","DOIUrl":"https://doi.org/10.3897/folmed.68.e174430","url":null,"abstract":"<p><strong>Introduction: </strong>Cigarette smoking is a major modifiable risk factor for cardiovascular disease and acute myocardial infarction (MI). The prognostic impact of cumulative smoking exposure (pack-years) on post-MI outcomes remains uncertain. The controversial \"smoker's paradox\" suggesting better short-term prognosis in smokers has been largely attributed to younger age and fewer comorbidities. Prior studies frequently failed to quantify smoking intensity, stratify by MI subtype (STEMI vs. NSTEMI), or adequately adjust for confounders such as age and renal function.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Etiological spectrum of sexually transmitted infections in infertile men: a monocentric retrospective study. 不育男性性传播感染的病因谱：一项单中心回顾性研究。
Folia medica Pub Date : 2026-04-03 DOI: 10.3897/folmed.68.e172980
Blagovest Petrov, Kostadin Kostadinov, Ivan Dechev, Krasimira Eneva
{"title":"Etiological spectrum of sexually transmitted infections in infertile men: a monocentric retrospective study.","authors":"Blagovest Petrov, Kostadin Kostadinov, Ivan Dechev, Krasimira Eneva","doi":"10.3897/folmed.68.e172980","DOIUrl":"https://doi.org/10.3897/folmed.68.e172980","url":null,"abstract":"<p><strong>Background: </strong>Sexually transmitted infections (STIs) have been linked to male infertility; however, the available evidence from Eastern Europe is inconclusive.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reversible pulmonary function impairment in female patients with nickel sensitization: a cross-sectional observational study. 镍致敏女性患者的可逆性肺功能损害：一项横断面观察研究。
Folia medica Pub Date : 2026-04-03 DOI: 10.3897/folmed.68.e177549
Burim Neziri, Shqipe Devaja, Samir Durmishi
{"title":"Reversible pulmonary function impairment in female patients with nickel sensitization: a cross-sectional observational study.","authors":"Burim Neziri, Shqipe Devaja, Samir Durmishi","doi":"10.3897/folmed.68.e177549","DOIUrl":"10.3897/folmed.68.e177549","url":null,"abstract":"<p><strong>Introduction: </strong>Nickel allergy is among the most common contact hypersensitivities worldwide. It affects women predominantly. This study examined whether female nickel-sensitized patients exhibit reversible changes in pulmonary function following a period of nickel avoidance.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum microRNA-122 as a potential biomarker for early detection and monitoring of type 2 diabetes mellitus: a cross-sectional study. 血清microRNA-122作为2型糖尿病早期检测和监测的潜在生物标志物：一项横断面研究
Folia medica Pub Date : 2026-04-03 DOI: 10.3897/folmed.68.e171319
Hiba Dawood, Qutaiba Qasim
{"title":"Serum microRNA-122 as a potential biomarker for early detection and monitoring of type 2 diabetes mellitus: a cross-sectional study.","authors":"Hiba Dawood, Qutaiba Qasim","doi":"10.3897/folmed.68.e171319","DOIUrl":"https://doi.org/10.3897/folmed.68.e171319","url":null,"abstract":"<p><strong>Introduction: </strong>MicroRNAs (miRNAs) are small noncoding RNAs with transcriptional repressive properties. Type 2 diabetes mellitus (T2DM) is closely associated with endothelial dysfunction and altered molecular signaling. Although microRNA-122 (miR-122) is highly abundant in the liver and contributes to lipid homeostasis, its significance in predicting long-term metabolic disease risk remains insufficiently understood.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic drug monitoring of adalimumab for dose optimization during maintenance therapy in patients with ulcerative colitis: real-world data. 溃疡性结肠炎患者维持治疗期间阿达木单抗剂量优化的治疗药物监测：真实世界数据
Folia medica Pub Date : 2026-04-03 DOI: 10.3897/folmed.68.e170410
Ahmed Mansur Kadhim, Dheyaa Jabbar Kadhim, Raghad Jawad Hussein
{"title":"Therapeutic drug monitoring of adalimumab for dose optimization during maintenance therapy in patients with ulcerative colitis: real-world data.","authors":"Ahmed Mansur Kadhim, Dheyaa Jabbar Kadhim, Raghad Jawad Hussein","doi":"10.3897/folmed.68.e170410","DOIUrl":"https://doi.org/10.3897/folmed.68.e170410","url":null,"abstract":"<p><strong>Introduction: </strong>Ulcerative colitis (UC) is a chronic inflammatory disease that primarily affects the colon. Tumor necrosis factor-α inhibitors (like adalimumab) are effective agents for UC. However, loss of response may occur. Proactive therapeutic drug monitoring involves measuring drug levels at regular intervals in patients in remission to maintain therapeutic concentrations and potentially prevent loss of response.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microorganisms associated with black tooth stain and contemporary strategies for their management. 与黑牙斑相关的微生物及其当代管理策略。
Folia medica Pub Date : 2026-04-03 DOI: 10.3897/folmed.68.e175900
Kristina Tabutova, Maria Shindova
{"title":"Microorganisms associated with black tooth stain and contemporary strategies for their management.","authors":"Kristina Tabutova, Maria Shindova","doi":"10.3897/folmed.68.e175900","DOIUrl":"10.3897/folmed.68.e175900","url":null,"abstract":"<p><strong>Introduction: </strong>Black stain is an extrinsic tooth discoloration, characterized by dark lines or incomplete pigmentation along the gingival margin in the cervical third of the tooth. They can affect both primary and permanent dentitions.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognosis of acute stroke patients monitored in neurological intensive care unit. 神经内科重症监护病房监测急性脑卒中患者预后分析。
Folia medica Pub Date : 2026-04-03 DOI: 10.3897/folmed.68.e173599
Hulya Özkan, Serefnur Ozturk
{"title":"Prognosis of acute stroke patients monitored in neurological intensive care unit.","authors":"Hulya Özkan, Serefnur Ozturk","doi":"10.3897/folmed.68.e173599","DOIUrl":"10.3897/folmed.68.e173599","url":null,"abstract":"<p><strong>Introduction: </strong>Stroke is the second most common cause of death in the world. Identifying the factors that influence stroke prognosis in advance is important to take the necessary precautions and improve the patient's chances of survival.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"68 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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