{"title":"Burning mouth syndrome - known and unknown.","authors":"Zlatina Tomova, Atanas Chonin, Radka Cholakova, Iliyana Stoeva","doi":"10.3897/folmed.66.e139442","DOIUrl":"10.3897/folmed.66.e139442","url":null,"abstract":"<p><p>The aim of this literature review was to provide a brief perspective over the scientific research of the condition known as burning mouth syndrome. Information from review articles, original studies, and dissertations was gathered using keywords describing etiological factors, clinical, laboratory findings and treatment protocols. We compiled information on potential etiological factors, symptoms, and potential treatments from the fifty-three included studies on dental and general health issues in patients complaining of burning sensations in their mouths. Despite the numerous attempts by dental and medical professionals to diagnose and treat mouth burning, the etiology and pathogenesis of this disorder remain rather unclear. In most cases, it is concluded that further research is needed with the inclusion of more patients, administering a long-term therapy, and monitoring the results.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"770-775"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-12-31DOI: 10.3897/folmed.66.e129478
Atanaska Petrova, Ivan N Ivanov, Liubomir Paunov, Angel Uchikov, Ivan Stoikov, Todor Kantardjiev, Marianna Murdjeva
{"title":"First VIM-producing representative of <i>Pseudomonas putida</i> group from the largest Bulgarian hospital.","authors":"Atanaska Petrova, Ivan N Ivanov, Liubomir Paunov, Angel Uchikov, Ivan Stoikov, Todor Kantardjiev, Marianna Murdjeva","doi":"10.3897/folmed.66.e129478","DOIUrl":"https://doi.org/10.3897/folmed.66.e129478","url":null,"abstract":"<p><p>Here we describe the first detected VIM-2-producing representative of Pseudomonasputida group - Pseudomonaskurunegalensis from the largest Bulgarian hospital - St George University Hospital in Plovdiv.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"905-910"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimizing orthodontic anchorage: comparative evaluation of larger diameter, shorter length mini-implants for enhanced mechanical stability.","authors":"Swapnil Junnarkar, Anand Sabane, Amol Patil, Meenal Tepan, Tanisha Rout, Sonakshi Sharma, Arati Gholap","doi":"10.3897/folmed.66.e130813","DOIUrl":"https://doi.org/10.3897/folmed.66.e130813","url":null,"abstract":"<p><strong>Aim: </strong>We aim to assess and contrast the mechanical stability of two mini-implant designs, featuring larger diameters and shorter lengths, for orthodontic anchorage against a conventional group of implants.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"849-862"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-12-31DOI: 10.3897/folmed.66.e126615
Areti Kalfoutzou, Aikaterini Doumana, Aimilia-Iris Karamolegkou, Adam Mylonakis, Christos Piperis, Maria Dimitrakoudi, Eleni Mostratou
{"title":"DRESSed for distress: a case of allopurinol-induced DRESS syndrome.","authors":"Areti Kalfoutzou, Aikaterini Doumana, Aimilia-Iris Karamolegkou, Adam Mylonakis, Christos Piperis, Maria Dimitrakoudi, Eleni Mostratou","doi":"10.3897/folmed.66.e126615","DOIUrl":"10.3897/folmed.66.e126615","url":null,"abstract":"<p><p>DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) syndrome is a severe systemic drug reaction characterized by a latent period of several weeks following the initiation of drug therapy. Among the most well-known causative agents is allopurinol, commonly prescribed for managing asymptomatic gout. Allopurinol-induced DRESS syndrome is associated with high mortality rates and significant long-term sequelae. This report details the case of an elderly female patient who presented with an extensive rash covering her trunk and extremities which was concurrent with her use of allopurinol. The condition progressed to renal impairment but showed significant improvement upon cessation of the drug and administration of high-dose corticosteroids. This case aims to shed light on one of the most underrecognized types of systemic drug reactions, hoping to raise awareness about this rare yet serious complication of one of the most widely prescribed drugs.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"929-934"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of rare anatomic variants - publication bias due to selective reporting in meta-analyses studies.","authors":"Vasileios Papadopoulos, Dimitrios Filippou, Aliki Fiska","doi":"10.3897/folmed.66.e137881","DOIUrl":"10.3897/folmed.66.e137881","url":null,"abstract":"<p><strong>Introduction: </strong>Meta-analyses of prevalence studies reporting rare anatomic variants are prone to selective reporting of non-null, confirmatory results, thus resulting in publication bias.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"795-817"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective study of post-treatment <sup>131</sup>I SPECT/CT imaging for personalizing therapy of patients with differentiated thyroid cancer.","authors":"Sonya Sergieva, Teodor Sofiyanski, Bozhil Robev, Milena Dimcheva, Albena Fakirova","doi":"10.3897/folmed.66.e139177","DOIUrl":"https://doi.org/10.3897/folmed.66.e139177","url":null,"abstract":"<p><strong>Introduction: </strong>The absence of anatomical landmarks in the whole body scan makes it challenging to precisely localize 131I uptake, which is used to treat patients with differentiated thyroid cancer (DTC). Recently, SPECT/CT studies have been utilized to increase the diagnostic sensitivity and specificity.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"776-786"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-12-31DOI: 10.3897/folmed.66.e130873
Sevinç Külekçioğlu
{"title":"A prospective clinical study to evaluate the comparative effectiveness of dry needling and laser therapy in neck and upper back myofascial pain syndrome.","authors":"Sevinç Külekçioğlu","doi":"10.3897/folmed.66.e130873","DOIUrl":"https://doi.org/10.3897/folmed.66.e130873","url":null,"abstract":"<p><strong>Introduction: </strong>Myofascial pain syndrome (MPS) is a disorder of the musculoskeletal system that is distinguished by the presence of pain, tenderness, muscle spasms, restricted joint range of motion, fatigue, and, in rare cases, autonomic dysfunction.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"842-848"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-12-31DOI: 10.3897/folmed.66.e135281
Mihail Z Tanev, Georgi T Tomov, Kostadin G Georgiev, Ekaterina D Georgieva, Kamelia V Petkova-Parlapanska, Galina D Nikolova, Yanka D Karamalakova
{"title":"Evaluation of indocyanine green antimicrobial photodynamic therapy in radical species elimination: an <i>in vitro</i> study.","authors":"Mihail Z Tanev, Georgi T Tomov, Kostadin G Georgiev, Ekaterina D Georgieva, Kamelia V Petkova-Parlapanska, Galina D Nikolova, Yanka D Karamalakova","doi":"10.3897/folmed.66.e135281","DOIUrl":"https://doi.org/10.3897/folmed.66.e135281","url":null,"abstract":"<p><strong>Introduction: </strong>Antimicrobial photodynamic therapy (aPDT) utilizes light-sensitive materials to inactivate pathogens. Indocyanine green (ICG) is an FDA-approved photosensitizer known for its effective photo-thermal and photo-chemical properties.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"876-883"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation between microRNA-21 expression and overweight/obesity.","authors":"Shashwat Sinha, Babu Rajendran, Shomnath Vasagam, Jeyakumar Balakrishnan","doi":"10.3897/folmed.66.e137396","DOIUrl":"https://doi.org/10.3897/folmed.66.e137396","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity and overweight are chronic conditions characterized by excessive adiposity that negatively impact health. They are among the most significant risk factors for respiratory failure, diabetes mellitus, cardiovascular disease, and hypertension. Genetic factors may contribute to some of these conditions, but they are mainly associated with the lifestyle in the majority. However, neither genetics nor lifestyle can fully explain all cases. Recent studies have proven that microRNA-21 causes the systemic hypertension, many cardiac pathologies, and some cancers. MicroRNA-21 is viewed as an important future biomarker for many critical conditions. We explored the role of microRNA-21 in the causation of overweight and obesity. There is conflicting data about this association in the literature. Determining if there is an association may help us in better understanding and managing this condition.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 6","pages":"825-833"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}