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Congenital extrahepatic portosystemic shunt in a teenager: a case report. 一名青少年的先天性肝外门静脉分流：病例报告。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e124107
Daniela Arias-Mariño, Alejandro Rojas-Urrea, Duvan Felipe Velandia-Siabato, Marlon Alberto Orozco-Mojica, Andres Manuel Bohorquez-Diaz, Lorena García-Agudelo
{"title":"Congenital extrahepatic portosystemic shunt in a teenager: a case report.","authors":"Daniela Arias-Mariño, Alejandro Rojas-Urrea, Duvan Felipe Velandia-Siabato, Marlon Alberto Orozco-Mojica, Andres Manuel Bohorquez-Diaz, Lorena García-Agudelo","doi":"10.3897/folmed.66.e124107","DOIUrl":"https://doi.org/10.3897/folmed.66.e124107","url":null,"abstract":"<p><p>The congenital extrahepatic portosystemic shunt is a rare anomaly characterized by aplasia or hypoplasia of intrahepatic portal venous branches that generate complete or partial extrahepatic shunting of portal venous intra-systemic veins. The clinical presentation is variable, including nausea, abdominal pain, anorexia, and jaundice. This entity has been associated with other congenital anomalies, and the most common are the cardiovascular anomalies. Imaging studies are essential to confirm the diagnosis, establish pre-operative planning, and determine the surgical procedure to be performed. We presented the case of a 15-year-old adolescent who had abdominal symptoms and was found to have a portal venous vascular abnormality.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"726-730"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Schwannomas of the upper limb: Clinical presentation, preoperative management and outcomes of surgical treatment. 上肢许旺瘤：临床表现、术前处理和手术治疗效果。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e135490
Edoardo Ipponi, Elena Bechini, Martina Cordoni, Fabrizia Gentili, Francesco Rosario Campo, Fabio Cosseddu, Antonio D'Arienzo, Paolo Domenico Parchi, Lorenzo Andreani
{"title":"Schwannomas of the upper limb: Clinical presentation, preoperative management and outcomes of surgical treatment.","authors":"Edoardo Ipponi, Elena Bechini, Martina Cordoni, Fabrizia Gentili, Francesco Rosario Campo, Fabio Cosseddu, Antonio D'Arienzo, Paolo Domenico Parchi, Lorenzo Andreani","doi":"10.3897/folmed.66.e135490","DOIUrl":"10.3897/folmed.66.e135490","url":null,"abstract":"<p><strong>Inroduction: </strong>Schwannomas are the most common tumors of the peripheral nervous system. Surgical eradication with excision or enucleation is the treatment for symptomatic and large schwannomas.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"618-628"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Lactobacillus plantarum supplementation on trimethylamine-N-oxide levels in 30 patients with atherosclerotic cardiovascular disease: A double-blind randomized controlled trial. 补充植物乳杆菌对 30 名动脉粥样硬化性心血管疾病患者体内三甲胺-N-氧化物水平的影响：双盲随机对照试验
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e132325
Natalia Spasova, Desislava Somleva, Bozhidar Krastev, Rositsa Tropcheva, Dobrin Svinarov, Todor Kundurzhiev, Elena Kinova, Assen Goudev
{"title":"Effect of <i>Lactobacillus plantarum</i> supplementation on trimethylamine-N-oxide levels in 30 patients with atherosclerotic cardiovascular disease: A double-blind randomized controlled trial.","authors":"Natalia Spasova, Desislava Somleva, Bozhidar Krastev, Rositsa Tropcheva, Dobrin Svinarov, Todor Kundurzhiev, Elena Kinova, Assen Goudev","doi":"10.3897/folmed.66.e132325","DOIUrl":"10.3897/folmed.66.e132325","url":null,"abstract":"<p><strong>Introduction: </strong>Trimethylamine-N-oxide (TMAO) is a metabolite produced by intestinal microbiota. It is well recognized as an independent risk marker for cardiovascular and renal diseases and mortality.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"682-691"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolomic biomarkers in amniotic fluid for early diagnosis of preterm birth and fetal growth restriction. 用于早期诊断早产和胎儿生长受限的羊水代谢生物标志物。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e137403
Charalampos Kolvatzis, Konstantinos Tsiantas, Ioannis Tsakiridis, Paris Christodoulou, Antigoni Cheilari, Ioannis Kalogiannidis, Panagiotis Zoumpoulakis, Apostolos Athanasiadis
{"title":"Metabolomic biomarkers in amniotic fluid for early diagnosis of preterm birth and fetal growth restriction.","authors":"Charalampos Kolvatzis, Konstantinos Tsiantas, Ioannis Tsakiridis, Paris Christodoulou, Antigoni Cheilari, Ioannis Kalogiannidis, Panagiotis Zoumpoulakis, Apostolos Athanasiadis","doi":"10.3897/folmed.66.e137403","DOIUrl":"https://doi.org/10.3897/folmed.66.e137403","url":null,"abstract":"<p><p>Preterm birth, affecting about 10% of pregnancies, significantly contributes to perinatal morbidity and mortality. Recent research indicates that metabolomics could enhance pregnancy outcomes and reduce costs by identifying biomarkers related to common pregnancy complications. Our team focused on analyzing amniotic fluid collected during the second trimester to identify potential biomarkers for preterm birth using 1H-NMR metabolomic analysis. We compared amniotic fluid samples from women who delivered prematurely with those who delivered at term. Multivariate principal component analysis revealed dimethylglycine, glucose, myo-inositol, and succinic acid as potential biomarkers for preterm birth prognosis and early diagnosis. Further analysis demonstrated distinct regulation patterns of these metabolites in relation to fetal growth centiles. For instance, dimethylglycine and glucose were upregulated in fetuses above the 20th centile, while citrate and succinate were upregulated in those below it. With Area Under the Curve (AUROC) values over 0.75 and p-values less than 0.05, these metabolites show promise as reliable biomarkers for predicting fetal growth restriction. This approach could significantly impact maternal-fetal medicine by facilitating early diagnosis and personalized interventions. Future research should focus on validating these findings in larger populations and exploring the underlying mechanisms of metabolite regulation.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"717-720"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracoabdominal approach to large adrenal tumors - when laparoscopic adrenalectomy is not enough: a retrospective four-year study. 当腹腔镜肾上腺切除术无法满足需要时--大型肾上腺肿瘤的胸腹入路：一项为期四年的回顾性研究。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e130680
Konstantinos Tsalis, Orestis Ioannidis, Natalia Antigoni Savvala, Grigorios Gkasdaris, Panagiotis Christidis, Elissavet Anestiadou, Ioannis Mantzoros, Manousos Pramateftakis, Efstathios Kotidis, Nikolaos Ouzounidis, Vasilis Foutsitzis, Savvas Symeonidis, Stefanos Bitsianis, Angeliki Cheva, Stamatios Angelopoulos
{"title":"Thoracoabdominal approach to large adrenal tumors - when laparoscopic adrenalectomy is not enough: a retrospective four-year study.","authors":"Konstantinos Tsalis, Orestis Ioannidis, Natalia Antigoni Savvala, Grigorios Gkasdaris, Panagiotis Christidis, Elissavet Anestiadou, Ioannis Mantzoros, Manousos Pramateftakis, Efstathios Kotidis, Nikolaos Ouzounidis, Vasilis Foutsitzis, Savvas Symeonidis, Stefanos Bitsianis, Angeliki Cheva, Stamatios Angelopoulos","doi":"10.3897/folmed.66.e130680","DOIUrl":"https://doi.org/10.3897/folmed.66.e130680","url":null,"abstract":"<p><strong>Introduction: </strong>Laparoscopic adrenalectomy is considered to be the gold standard approach in the field of adrenal surgery. This technique offers advantages of great importance compared to variant laparotomy techniques. Notwithstanding, a technique that needs to be mentioned is the thoracoabdominal approach which facilitates the anatomic exposure of the retroperitoneum, adrenal gland, and great vessels and is strongly recommended for the surgery of large, malignant adrenal tumors.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"637-644"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlating the genetic alterations and expression profile of the TRA2B gene in HNSCC and LUSC. HNSCC和LUSC中TRA2B基因遗传改变和表达谱的相关性。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e117367
Amba Esakki, Anitha Pandi, Smiline A S Girija, Vijayashree Priyadharsini Jayaseelan
{"title":"Correlating the genetic alterations and expression profile of the <i>TRA2B</i> gene in HNSCC and LUSC.","authors":"Amba Esakki, Anitha Pandi, Smiline A S Girija, Vijayashree Priyadharsini Jayaseelan","doi":"10.3897/folmed.66.e117367","DOIUrl":"https://doi.org/10.3897/folmed.66.e117367","url":null,"abstract":"<p><strong>Introduction: </strong>Transformer (TRA2B) is a serine/arginine-rich (SR)-like protein family that regulates the alternative splicing of several genes in a concentration-dependent manner. Amplification of the TRA2B gene, which codes for TRA2B, occurs in several malignancies, including those of the lung, cervix, head and neck, ovary, stomach, and uterine.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"673-681"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual and refractive outcome after 12 years of treatment of type 1 prethreshold retinopathy of prematurity. 1 型阈前早产儿视网膜病变治疗 12 年后的视力和屈光效果。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e133949
Vasil G Marinov, Nelly P Sivkova, Maya B Krasteva, Kiril K Simitchiev
{"title":"Visual and refractive outcome after 12 years of treatment of type 1 prethreshold retinopathy of prematurity.","authors":"Vasil G Marinov, Nelly P Sivkova, Maya B Krasteva, Kiril K Simitchiev","doi":"10.3897/folmed.66.e133949","DOIUrl":"https://doi.org/10.3897/folmed.66.e133949","url":null,"abstract":"<p><strong>Aim: </strong>In this study, the best corrected visual acuity (BCVA) and refraction in preterm-born infants in South-Eastern Bulgaria after 12 years of treatment for type 1 prethreshold retinopathy of prematurity were presented, and the outcomes of laser treatment and cryotherapy were compared.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"645-652"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attitudes and awareness related to cervical cancer vaccine. 对宫颈癌疫苗的态度和认识。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e130668
Darina N Ruschukova, Teodora D Momchilova, Marieta S Vladimirova, Zlatina I Nikolova, Krikor O Indjian
{"title":"Attitudes and awareness related to cervical cancer vaccine.","authors":"Darina N Ruschukova, Teodora D Momchilova, Marieta S Vladimirova, Zlatina I Nikolova, Krikor O Indjian","doi":"10.3897/folmed.66.e130668","DOIUrl":"https://doi.org/10.3897/folmed.66.e130668","url":null,"abstract":"<p><strong>Introduction: </strong>Cervical cancer causes major morbidity and mortality around the world. This makes prophylactic vaccines a significant tool for preventing the disease. As these vaccines become more widely available, they have the potential to drastically lower the cancer's prevalence and burden in the future.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"707-716"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment of pulmonary hydatid disease: a nine-year single-center experience. 肺包虫病的手术治疗：九年单中心经验。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e134503
Petar Uchikov, Nedzhat Ali, Milena Sandeva, Krasimir Kraev, Krasimira Eneva, Bozhidar Hristov, Mariya Kraeva, Elizabet Dzhambazova, Daniela Taneva, Tihomir Tenchev, Angel Uchikov
{"title":"Surgical treatment of pulmonary hydatid disease: a nine-year single-center experience.","authors":"Petar Uchikov, Nedzhat Ali, Milena Sandeva, Krasimir Kraev, Krasimira Eneva, Bozhidar Hristov, Mariya Kraeva, Elizabet Dzhambazova, Daniela Taneva, Tihomir Tenchev, Angel Uchikov","doi":"10.3897/folmed.66.e134503","DOIUrl":"https://doi.org/10.3897/folmed.66.e134503","url":null,"abstract":"<p><strong>Introduction: </strong>Hydatidosis is one of the most critical parasitic zoonotic diseases worldwide. Lungs are the second most common site of the disease.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"653-661"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant dorsal liposarcoma in an elderly man: a case report. 一名老年男性的巨大背侧脂肪肉瘤：病例报告。
Folia medica Pub Date : 2024-10-31 DOI: 10.3897/folmed.66.e125471
Daniela Arias-Mariño, Alejandro Rojas-Urrea, Diego Herrera-Salcedo, Lorena García-Agudelo
{"title":"Giant dorsal liposarcoma in an elderly man: a case report.","authors":"Daniela Arias-Mariño, Alejandro Rojas-Urrea, Diego Herrera-Salcedo, Lorena García-Agudelo","doi":"10.3897/folmed.66.e125471","DOIUrl":"https://doi.org/10.3897/folmed.66.e125471","url":null,"abstract":"<p><p>Liposarcoma is a malignant mesenchymal tumor defined as a rare cancer due to its low incidence rate. The most common location of liposarcoma is in the extremities, followed by retroperitoneum, with the bone and trunk being the less frequent presentations. The most common histological subtype is well-differentiated liposarcoma, which has the highest local recurrence, is slow-growing, and is insensitive to chemo and radiotherapy. We present the case of a 62-year-old male patient with a 10-year-growth mass in the dorsal region. A computed tomography scan showed a huge mass in the right dorsal space with a malignant lipomatous appearance, which required surgical removal of a mass of 2,800 g.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 5","pages":"749-754"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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