Folia medica最新文献_第10页

Atypical clinical and radiologic findings in a patient with brain metastatic lesions 脑转移病变患者的非典型临床和放射学表现

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e84810

Eray Halil, Ekaterina Viteva, Georgi Vasilev, Krasimir Shukerski, Penka Atanassova

{"title":"Atypical clinical and radiologic findings in a patient with brain metastatic lesions","authors":"Eray Halil, Ekaterina Viteva, Georgi Vasilev, Krasimir Shukerski, Penka Atanassova","doi":"10.3897/folmed.65.e84810","DOIUrl":"https://doi.org/10.3897/folmed.65.e84810","url":null,"abstract":"We report the case of a 47-year-old man who was admitted to our clinic with an intractable headache, nausea, and sporadic vomiting, as well as speech difficulties and a ‘floating’ sensation. This man had no prior medical history. MRI of the brain showed evidence of over 20 supra- and infratentorial capsulated ring-enhancing lesions. All other paraclinical investigations done in our clinic were unremarkable and we excluded our first assumption of neurocysticercosis, as well as other parasitic infections. The patient was then referred to the Oral and Maxillofacial Surgery Clinic for an excisional biopsy of a submandibular formation, which was later verified to represent a lymph node metastasis from a poorly differentiated adenocarcinoma. A chest X-ray failed to demonstrate any significant pathology and the immunohistochemical constellation of the lymph node metastasis excluded the possibility of the primary tumor originating in the lung or the prostate. Due to the unresolved diagnostic query, a whole-body PET/CT was performed demonstrating a formation with malignant characteristics in the basal segment of the left lung, reaching the pleura and the left hilum, as well as solitary enlarged mesenteric and mediastinal lymph nodes. Following clinical consultations, it was determined that the patient was inoperable and chemotherapy and palliative CNS irradiation were recommended.","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135868724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of 38% silver diamine fluoride on fracture resistance of leucite reinforced feldspathic ceramic CAD/CAM class I inlay restorations Effect 38%氟化银二胺对白晶石增强长石陶瓷CAD/CAM I类镶嵌体修复体抗断裂性能的影响

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e97183

Egemen Sezen, Umut Kaya, Asli Topaloglu Ak, Miray Ay

{"title":"Effect of 38% silver diamine fluoride on fracture resistance of leucite reinforced feldspathic ceramic CAD/CAM class I inlay restorations","authors":"Egemen Sezen, Umut Kaya, Asli Topaloglu Ak, Miray Ay","doi":"10.3897/folmed.65.e97183","DOIUrl":"https://doi.org/10.3897/folmed.65.e97183","url":null,"abstract":"Introduction : Silver diamine fluoride (SDF) is a topical agent that has recently gained popularity for its ability to stop and prevent dental caries. Aim : The aim of this study was to evaluate the effect of SDF applied to class I cavities of extracted non-caries molar teeth on the fracture resistance of CAD/CAM block. Materials and methods : Twenty eight extracted noncarious molars were selected for the study. They were divided into two groups (n=14 per group). In each tooth, a diamond head was used to create Class I cavities that were 2 mm deep and 2 mm wide. The fracture strength test was carried out by applying a force at a speed of 5 mm/min, while continuously increasing the long axis of the tooth at the point corresponding to the central fossa. Results : SDF application did not have a statistically significant effect on fracture resistance in teeth restored with Class I cavities CAD/CAM blocks. The two groups did not differ statistically significantly according to the two-way ANOVA [mean fracture force (N) ± standard deviation: without SDF 1138.19±581.65 and with SDF 1067.93±555.65; p =0.712]. Conclusions : This study showed that SDF did not have either a positive or negative effect on the fracture resistance for restoration or easy application in cavities. Long-term clinical studies with different mechanical tests are needed for the safe use of SDF in pre-restoration cavities with CAD/CAM blocks.","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135863416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of body weight and psychological characteristics on periodontal disease development 体重和心理特征对牙周病发展的影响

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e98856

Maksym Skrypnyk, Tatiana Petrushanko, Karine Neporada, Nataliia Vynnyk, Margarita Skikevych, Igor Skrypnyk

{"title":"The effect of body weight and psychological characteristics on periodontal disease development","authors":"Maksym Skrypnyk, Tatiana Petrushanko, Karine Neporada, Nataliia Vynnyk, Margarita Skikevych, Igor Skrypnyk","doi":"10.3897/folmed.65.e98856","DOIUrl":"https://doi.org/10.3897/folmed.65.e98856","url":null,"abstract":"Aim : The aim of the study was to examine the association between periodontal health in young patients with various body mass indexes and psychological traits such as temperament, level of anxiety, and autonomic nervous system tone. Materials and methods : The study included 132 male and female subjects aged 18–22 years with different body mass indexes (BMI). They were allocated into four groups by their BMIs: normal weight, overweight, and first- and second-degree obesity. We completed periodontal charts for all patients and evaluated basic oral hygiene and periodontal indexes, such as the Green-Vermillion index (OHI), the approximal plaque index by Lange (API), and papilla bleeding index by Saxer & Mühlemann (PBI). Eysenck personality questionnaire, the state-trait anxiety inventory of Spielberger-Khanin, and Wayne questionnaire were used to determine the psychological characteristics. Results : Patients with the first and second degrees of obesity were found to have the highest prevalence and severity of generalized gingivitis (up to 90%). Patients with normal BMI had significantly lower levels of extraversion and higher levels of neuroticism than the obese individuals, while subjects with extra weight and normal BMI were more emotionally stable. We found no evidence that choleric or melancholic temperament had an impact on BMI or periodontal health. However, phlegmatic temperament was found to be linked to a normal BMI, good oral hygiene, and an intact periodontium, while sanguine temperament was linked to obesity and gingivitis in young adults. A significantly higher level of state and trait anxiety was observed in obese individuals. Fifty percent of the obese subjects had disturbances of the functional state of the cardiovascular system and the tone of the autonomic nervous system. Conclusions : Because obesity and periodontal pathology are multifactorial diseases linked to lifestyle, stress tolerance, and habits, personality temperament may play a causal role in their development.","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135871182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic benefits of 18F-FDG PET/CT in cases of prosthetic infective endocarditis 18F-FDG PET/CT在假体感染性心内膜炎病例中的诊断价值

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e98732

Bistra Dobreva-Yatseva, Fedya Nikolov, Ralitsa Raycheva, Albena Botushanova, Maria Koleva, Mariya Tokmakova

引用次数: 0

Duplicated gallbladder: an incidental anatomical variation in a patient with symptomatic cholelithiasis 胆囊重复:有症状的胆石症患者的偶然解剖变异

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e91397

Ludmila Baltaga, Dimosthenis Chrysikos, Spiros Delis, Charina Triantopoulou, Dimitrios Filippou, Vasileios Protogerou, Theodore Troupis

引用次数: 0

The role of prophylactic parathyroidectomy during thyroidectomy for MTC in patients with MEN2A syndrome 预防性甲状旁腺切除术在MEN2A综合征MTC患者甲状腺切除术中的作用

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e86749

Christos Kavazis, Konstantinos Romanidis, Michail Pitiakoudis, Isaak Kesisoglou, Styliani Laskou, Konstantinos Sapalidis

{"title":"The role of prophylactic parathyroidectomy during thyroidectomy for MTC in patients with MEN2A syndrome","authors":"Christos Kavazis, Konstantinos Romanidis, Michail Pitiakoudis, Isaak Kesisoglou, Styliani Laskou, Konstantinos Sapalidis","doi":"10.3897/folmed.65.e86749","DOIUrl":"https://doi.org/10.3897/folmed.65.e86749","url":null,"abstract":"Aim : To define the role of prophylactic parathyroidectomy in the surgical treatment of medullary thyroid carcinoma (MTC) in multiple endocrine neoplasia type IIa (MEN2A) syndrome through a literature review. Materials and methods : The database of PubMed was searched using the terms “parathyroidectomy” and “medullary” in the fields “Title” and “Abstract”, as well as the Google Scholar database. Articles without references to parathyroid management strategies were mainly excluded. Results : Fourteen articles were reviewed as relevant to this study regarding recommendations for the management of parathyroids during prophylactic thyroidectomy in patients with MTC in MEN2A syndrome. Three of them had the same or similar purpose to our work, and the most recent literature review did not clearly support either one of the two management strategies. References to parathyroid management were found in the rest of the articles, but their purpose was not to determine the appropriate management strategy. The majority of the authors support the preservation of macroscopically normal parathyroid glands, while one study favored routine total parathyroidectomy and autografting. Conclusions : Although there does not seem to be a gold standard, the strategy of preserving macroscopically normal parathyroid glands with routine lab testing and surgical exploration for hyperparathyroidism during thyroidectomy seems to be a safe and effective strategy.","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traumatic head injuries in Moldova: a cross-sectional analysis of medical registry data 摩尔多瓦的创伤性头部损伤:医疗登记数据的横断面分析

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e91262

Svetlana Cociu, Cara J. Hamann, Serghei Cebanu, Angela Cazacu-Stratu, Mădălina Adina Coman, Corinne Peek-Asa

{"title":"Traumatic head injuries in Moldova: a cross-sectional analysis of medical registry data","authors":"Svetlana Cociu, Cara J. Hamann, Serghei Cebanu, Angela Cazacu-Stratu, Mădălina Adina Coman, Corinne Peek-Asa","doi":"10.3897/folmed.65.e91262","DOIUrl":"https://doi.org/10.3897/folmed.65.e91262","url":null,"abstract":"Aim : The aims of this study were to evaluate the demographics and crash profiles of road traffic-related traumatic brain injury (TBI) patients treated at two emergency departments in the Republic of Moldova, and to identify areas for prevention. Materials and methods : A prospective study was conducted using data from the medical records of a pilot TBI registry from the emergency departments of two large hospitals in Moldova. The study sample included patients with TBI related to road traffic mechanisms from March 1 to August 31, 2019. Results : During the study period, 368 patients were included in the TBI registry, with 113 (30.7%) of them having TBIs caused by traffic. Children under the age of 18 (44.2%), people aged 30-49 (18.6%), and males (71.7%) were the largest proportions of the road traffic-related TBI patient population. Most (78.8%) of the TBI injuries occurred in a transportation area (street, road, highway, etc.), among children under age of 18, while walking (36.7%) or riding in a passenger vehicle (68.4%). Pedestrians (42.5%) accounted for the most cases, followed by passengers (33.6%) and drivers (23.9%). Over two-thirds of all cases were tested for alcohol. Most cases were in June (20.4%) and between 2 pm and 6 pm (29.2%) within the research period. Conclusions : This is the first study to examine the road traffic-related traumatic brain injuries in the Republic of Moldova, which underlines the high burden of injuries among males, children, and the middle-aged population. Results from this study will help to support the development of a country’s national TBI registry and can argue for the running of comprehensive measures in road injury prevention targeted to the most affected populations","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135813732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the flexural strength of orthodontic acrylic resin incorporated with propolis nanoparticles: an in vitro study 评价正畸丙烯酸树脂与蜂胶纳米颗粒的抗弯强度:体外研究

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e90085

Azam Akhavan, Sepideh Arab, Negin Eslamiamirabadi, Ahmad Sodagar, Fatemeh Safari

{"title":"Evaluation of the flexural strength of orthodontic acrylic resin incorporated with propolis nanoparticles: an in vitro study","authors":"Azam Akhavan, Sepideh Arab, Negin Eslamiamirabadi, Ahmad Sodagar, Fatemeh Safari","doi":"10.3897/folmed.65.e90085","DOIUrl":"https://doi.org/10.3897/folmed.65.e90085","url":null,"abstract":"Aim : Nanopropolis has become the subject of interest in medicine and dentistry as a natural product due to its outstanding properties, particularly antimicrobial activity. This study aimed at investigating the effect of nanopropolis on flexural strength of polymethyl methacrylate (PMMA). Materials and methods : Three groups of two acrylic resin brands namely Acropars and Triplex containing 0 (control group), 0.5%, and 1% of nanopropolis were prepared in 64×10.0×3.3 mm according to ISO 20795-2 (2013). Fifteen samples were allocated to each concentration. Flexural strength was determined following immersion in water and incubation at 37°C for 50±2 hours using a universal testing machine at a crosshead speed of 5±1 mm/min. Data were analyzed using ANOVA, Tukey HSD, and t -test. P &lt;0.05 was set as statistical significance. Results : Control groups of Acropars and Triplex showed the highest mean flexural strength within their own group which both were higher than the recommended 50 MPa. The mean flexural strength of Triplex incorporated with 0.5 and 1% of nanopropolis was higher than that of Acropars with the same percentage. Conclusions : The mean flexural strength of Triplex remained above the recommended value of 50 MPa after incorporation of both 0.5 and 1% nanopropolis. However, that of Acropars dropped below it.","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135813834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methods and techniques for increasing the safety and efficacy of pulmonary vein isolation in patients with atrial fibrillation 提高房颤患者肺静脉隔离安全性和有效性的方法和技术

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e103031

Krasimir R. Dzhinsov

{"title":"Methods and techniques for increasing the safety and efficacy of pulmonary vein isolation in patients with atrial fibrillation","authors":"Krasimir R. Dzhinsov","doi":"10.3897/folmed.65.e103031","DOIUrl":"https://doi.org/10.3897/folmed.65.e103031","url":null,"abstract":"The most common type of sustained arrhythmia is atrial fibrillation (AF). Pulmonary vein isolation (PVI) is the cornerstone of catheter ablation for atrial fibrillation, which has emerged as the primary therapeutic strategy for atrial fibrillation patients. Unfortunately, about one-third of patients experience recurrent atrial arrhythmias after the procedure. The leading cause of AF recurrence after PVI, especially during the first year, is reconnection of the pulmonary veins. There are different techniques and methods that could increase the efficacy of the procedure by making durable pulmonary vein isolation. A literature search was conducted using the terms atrial fibrillation, ablation, pulmonary vein isolation, and durable PVI in the PubMed, Scopus, and Web of Science databases. Durable pulmonary vein isolation could be achieved by avoiding gaps in the ablation line and PV reconnections using pharmacological testing, waiting time, various indexes based on data from the electroanatomical mapping system, and special ablation catheters. Furthermore, detecting the gaps in the ablation line in the end of the procedure using different pacing and mapping techniques and application of additional energy to close those gaps could increase the success rate of the procedure. Most commonly, AF recurrence after PVI is due to PV reconnections caused by gaps in the ablation line. To achieve safer and more effective PVI, the procedure has to be standardized and operator-independent with reproducible success rate and safety profile.","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135813947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetes mellitus as a risk factor and comorbidity in gout 糖尿病是痛风的危险因素和合并症

Folia medica Pub Date : 2023-10-31 DOI: 10.3897/folmed.65.e91075

Larisa Rotaru, Liliana Groppa, Eugeniu Russu, Lia Chișlari, Cătălin Codreanu, Larisa Spinei, Oleg Arnaut, Cornelia Cornea

{"title":"Diabetes mellitus as a risk factor and comorbidity in gout","authors":"Larisa Rotaru, Liliana Groppa, Eugeniu Russu, Lia Chișlari, Cătălin Codreanu, Larisa Spinei, Oleg Arnaut, Cornelia Cornea","doi":"10.3897/folmed.65.e91075","DOIUrl":"https://doi.org/10.3897/folmed.65.e91075","url":null,"abstract":"Introduction : Metabolic disorders are a public health issue because of the complications they cause, but they are also a major risk factor for the onset of gout. Aim : The current study set out to demonstrate clinically how the clinical-paraclinical evaluation methodology had advanced as well as to assess comorbidity in gout patients using diabetes mellitus (DM). We also wanted to examine the pancreatic dysfunction in gout patients of different ages (by assessing the glucose and glycolated Hb analyses). Materials and methods : Two hundred gout patients (mean age, men 60±8.0 years, women 63±9.0 years) were included in a descriptive, cross-sectional study. The diagnosis of gout was made according to the classification criteria for gout according to ACR and EULAR 2015. The raw data were analyzed using SPSS v. 26.0. Results : In the study, type 2 diabetes mellitus (DM2) was encountered with a comparable frequency among both middle-aged and elderly patients (33.8% and 41.8%, respectively, p =0.26). In only 15% of cases, DM2 preceded the development of gout (in 3% with the beginning and 12% with late onset), while the developmental age of the DM2 prior to gout was comparable (50.9±2.8 years in age group 1 and 55.1±6.9 years in age group 2). We found that elderly people experience gout much more frequently (up to 41%) when DM2 is present. However, DM2 is not considered a predictor of gout. Conclusions : In gout patients under the age of 59 inclusive, the mean age at diabetes onset is significantly lower than the age (37.49.6 years) at which diabetes develops in the general population. Early onset of diabetes is associated with early development of gout.","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135870475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0