{"title":"Cognitive functions in a 29-year-old male with post-COVID syndrome and long-term psoriasis - a case study.","authors":"Miroslava Hristova, Radka Massaldjieva, Lyubomir Chervenkov, Penka Atanassova","doi":"10.3897/folmed.66.e124311","DOIUrl":"10.3897/folmed.66.e124311","url":null,"abstract":"<p><p>Post-acute COVID syndrome (PACS), or long COVID, is a newly defined condition emerging as a widespread post-pandemic diagnosis with prevalent neuro-psychiatric symptoms and possible neuroinflammation-associated pathogenetic mechanisms.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"587-591"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nonsurgical class III correction in adolescence using modified fixed reverse twin-block therapy and fixed appliances - a case series.","authors":"Harpreet Singh, Pinaki Roy, Raj Kumar Maurya, Poonam Sharma, Pranav Kapoor, Tanmay Mittal","doi":"10.3897/folmed.66.e119060","DOIUrl":"10.3897/folmed.66.e119060","url":null,"abstract":"<p><p>Skeletal class III malocclusion is a therapeutic challenge in orthodontic practice. Reverse functional appliances such as reverse twin block (RTB) are used to correct class III skeletal and occlusal disharmonies associated with functional anterior shift in growing patients. However, treatment options become limited with increasing age, especially when patients desire nonsurgical and nonextraction camouflage treatment. This report illustrates the successful nonsurgical treatment of class III malocclusion during adolescence and adulthood, exacerbated by a functional anterior shift that resulted in overclosure of the mandible. A modified fixed RTB was utilized to posture the mandible backwards, thereby inducing active clockwise rotation of the mandible. After treatment, patients demonstrated significantly improved maxillomandibular relationships, well-maintained stable occlusion, and facial esthetics. Satisfactory occlusal, esthetic, and functional outcomes achieved in the present cases underline the fact that dentoalveolar changes induced by fixed RTB can be utilized even past a patient's peak pubertal growth period to obtain changes that aid in correcting a class III malocclusion. A synergistic combination of modified fixed RTB therapy accompanied by comprehensive fixed mechanotherapy is a viable treatment alternative for the correction of aptly selected mild to moderate skeletal class III malocclusions associated with functional anterior shift, anterior crossbites, and mandibular overclosure.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"555-567"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reliability of Moyer's and Tanaka Johnston's prediction methods in a non-Caucasian heterogeneous population - a cross-sectional study.","authors":"Panchatcharam Barkavi, Mohamed Iqbal, Priyanka Gandhi, Harishma Sivakumar, Kavitha Mathivanan, Kothandaraman Thirivikhraman","doi":"10.3897/folmed.66.e126997","DOIUrl":"https://doi.org/10.3897/folmed.66.e126997","url":null,"abstract":"<p><strong>Introduction: </strong>Mixed dentition analyses are used to determine possible tooth-size and arch-length discrepancies during the transition from primary to permanent dentition. Prediction methods using a probability table or linear regression equation use the sum of the mesiodistal widths of mandibular permanent incisors to predict the mesiodistal width of unerupted permanent teeth. Racial and sexual variations and sexual dimorphism in tooth size have been reported. The objective of this study is to validate Moyer's and Tanaka Johnston's mixed dentition analyses in a contemporary South Indian population.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"521-527"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-08-31DOI: 10.3897/folmed.66.e120391
Daniel Markov, Petar Uchikov, Pavel Timonov, Galabin Markov, Elena Poryazova
{"title":"Primary pleomorphic breast sarcoma - a case report.","authors":"Daniel Markov, Petar Uchikov, Pavel Timonov, Galabin Markov, Elena Poryazova","doi":"10.3897/folmed.66.e120391","DOIUrl":"10.3897/folmed.66.e120391","url":null,"abstract":"<p><p>Primary mammary sarcomas are very rare, histologically heterogeneous non-epithelial malignant neoplasms. Primary undifferentiated pleomorphic sarcoma is a rare malignant mesenchymal tumor in the breast. It is characterized by marked cellular atypism and pleomorphism. Isolated cases with an aggressive course and poor prognosis have been commonly described in the literature. We present a rare case of a 62-year-old woman with an 18-cm solid tumor of the left breast, 6 months old, which grew rapidly during the last month. Physical examination and mammography revealed no enlarged lymph nodes in the left axilla. A total mastectomy was performed. The diagnosis of undifferentiated pleomorphic sarcoma is challenging due to the lack of specific immunohistochemical markers. It can only be made after excluding other types of soft tissue sarcomas. This report discusses the histopathological and immunohistochemical studies that were conducted. Our case is distinguished from others with the same diagnosis by the atypical clinical presentation, which is painless, and the spontaneous bleeding, as well as the large size of the tumor.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"568-573"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-08-31DOI: 10.3897/folmed.66.e127319
Krasimir Kraev, Petar Uchikov, Bozhidar Hristov, Maria Kraeva, Yordanka Basheva-Kraeva, Mladen Doykov, Stanislava Popova-Belova, Mariela Geneva-Popova
{"title":"Exploring the impact of curcumin on osteoarthritis symptomatology: correlations and insights from a Bulgarian cohort.","authors":"Krasimir Kraev, Petar Uchikov, Bozhidar Hristov, Maria Kraeva, Yordanka Basheva-Kraeva, Mladen Doykov, Stanislava Popova-Belova, Mariela Geneva-Popova","doi":"10.3897/folmed.66.e127319","DOIUrl":"https://doi.org/10.3897/folmed.66.e127319","url":null,"abstract":"<p><strong>Introduction: </strong>Osteoarthritis is a prevalent degenerative joint disorder associated with pain and functional impairment. Curcumin, a natural anti-inflammatory compound, has garnered attention for its potential therapeutic benefits in osteoarthritis management.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"461-465"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Could Madelung disease be a cause of stroke? A rare case report.","authors":"Bünyamin Tosunoğlu, Melih Altıkardeş, Elif Pınar Arık, Nilay Kaya, Levent Ertuğrul İnan","doi":"10.3897/folmed.66.e116329","DOIUrl":"10.3897/folmed.66.e116329","url":null,"abstract":"<p><p>Multiple symmetric lipomatosis (MLS), also known as Launois-Bensaude syndrome or Madelung disease, is a rare metabolic condition characterized by generally symmetrical, non-encapsulated fat accumulations in the patient's body.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"583-586"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between mandibular prognathism and Matrilin-1, bone morphogenic protein, Tyr67Asn, homeobox protein hox-A2, Rho-GTPase activating protein, and <i>Myosin 1H</i> genes in the Indian population.","authors":"Anish Doke, Anand Sabane, Amol Patil, Jayesh Rahalkar, Tulsi Subramaniam, Monali Nikalje","doi":"10.3897/folmed.66.e129047","DOIUrl":"10.3897/folmed.66.e129047","url":null,"abstract":"<p><strong>Introduction: </strong>Mandibular prognathism (MP) patients present with aesthetic concerns and functional issues, including difficulties in mastication and pronunciation. Studies revealed that mandibular prognathism had definitive Mendelian inheritance patterns. This study aimed to ascertain distinct genetic markers associated with mandibular prognathism in individuals of Indian descent, focusing on exploring the prevalent genetic variations associated with certain genes. This study sought to identify the association of the following gene markers with mandibular prognathism: 1) Matrilin-1 (MATN1) (rs1065755), 2) Bone morphogenic protein 3 (BMP-3) (Tyr67Asn), 3) Homeobox protein hox-A2 (HOXA2) (Val327Ile), 4) Rho-GTPase activating protein (ARHGAP 21) (Gly1121Ser), 5) Myosin 1H (MYO1H) (rs10850110).</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"528-535"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-08-31DOI: 10.3897/folmed.66.e129251
Rositsa Dimova, Ralitsa Raycheva, Pavlina Pavlova
{"title":"Application of the bow-tie analysis to improve patient safety - a lesson learned from clinical practice.","authors":"Rositsa Dimova, Ralitsa Raycheva, Pavlina Pavlova","doi":"10.3897/folmed.66.e129251","DOIUrl":"https://doi.org/10.3897/folmed.66.e129251","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to assess the risk management of drug safety in an operating theater setting within a hospital-based treatment facility.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"549-554"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-08-31DOI: 10.3897/folmed.66.e123766
Krikor Giragosyan, Ivan Chenchev, Vasilena Ivanova
{"title":"Linear bone gain and healing complication rate comparative outcomes following ridge augmentation with custom 3D printed titanium mesh vs Ti-reinforced dPTFE. A randomized clinical trial.","authors":"Krikor Giragosyan, Ivan Chenchev, Vasilena Ivanova","doi":"10.3897/folmed.66.e123766","DOIUrl":"10.3897/folmed.66.e123766","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this randomized clinical trial was to compare the qualitative (linear alveolar ridge changes) and quantitative (healing complications) outcomes after guided bone regeneration (GBR) using a custom-made 3D printed titanium mesh versus titanium reinforced dense PTFE membrane for vertical and horizontal augmentation of deficient alveolar ridges.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"505-514"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Folia medicaPub Date : 2024-08-31DOI: 10.3897/folmed.66.e127273
Mariya Ivanova, Anna Todorova, Daniela Grekova-Kafalova
{"title":"Impact of working environment on the level of occupational burnout among community pharmacists - a pilot study.","authors":"Mariya Ivanova, Anna Todorova, Daniela Grekova-Kafalova","doi":"10.3897/folmed.66.e127273","DOIUrl":"https://doi.org/10.3897/folmed.66.e127273","url":null,"abstract":"<p><strong>Introduction: </strong>The disorder known as burnout develops as a reaction to the damaging impacts of workplace stress. When occupational stress is poorly managed, it can result in burnout, which has a detrimental impact on workers' performance and emotional and physical well-being. Those who work in the helping profession are the most vulnerable. Pharmacy practitioners are among the most vulnerable groups in the healthcare industry.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"66 4","pages":"536-542"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}