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Serum Vitamin D levels in males with premature androgenetic alopecia: a prospective case-control study. 男性早发性雄激素性脱发患者血清维生素D水平：一项前瞻性病例对照研究
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e138514
Rehana Batool, Seemab Khan, Hur Abbas, Syed Muhammad Abbas, Mirza Shaheer Hyder, Syed Arbab Shah, Muhammad Raza Sarfraz, Humera Fiaz
{"title":"Serum Vitamin D levels in males with premature androgenetic alopecia: a prospective case-control study.","authors":"Rehana Batool, Seemab Khan, Hur Abbas, Syed Muhammad Abbas, Mirza Shaheer Hyder, Syed Arbab Shah, Muhammad Raza Sarfraz, Humera Fiaz","doi":"10.3897/folmed.67.e138514","DOIUrl":"https://doi.org/10.3897/folmed.67.e138514","url":null,"abstract":"<p><strong>Introduction: </strong>Androgenetic alopecia (AGA), the predominant form of hair loss, affects a significant global population. While emerging research suggests a potential correlation between serum vitamin D levels and AGA severity, the current body of evidence remains inconclusive, necessitating further investigation to elucidate this relationship and its clinical implications.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The contemporary role of lactate in exercise physiology and exercise prescription - a review of the literature. 乳酸盐在运动生理学和运动处方中的当代作用-文献综述。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e144693
Nikolay Mandadzhiev
{"title":"The contemporary role of lactate in exercise physiology and exercise prescription - a review of the literature.","authors":"Nikolay Mandadzhiev","doi":"10.3897/folmed.67.e144693","DOIUrl":"https://doi.org/10.3897/folmed.67.e144693","url":null,"abstract":"<p><p>Lactate is a key molecule in exercise metabolism. In the last two decades, there has been a revolution in the understanding of its role - from a byproduct of hypoxic muscles to a major energy resource and a signaling molecule - 'lactormone'. The aim of this review is to compile all the up-to-date information that is available on the general metabolism of lactate, but also the specific use that exercise physiologists, coaches, and athletes can get out of lactate measurements, lactate-based training zones, and periodization of training sessions. Since the revolution in the understanding of lactate's role in normal metabolism and disease in the late 20th century, more evidence has been assembled regarding the specific part it plays in exercise. From the vast body of knowledge, the researchers developed the concept of training intensity distribution into zones according to the level of blood lactate. The end goal of training to a specific lactate level or 'threshold' is the increased adaptation to specific training stimuli and ultimately better performance, which has been backed up by the achievements of numerous athletes training according to this concept.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micro-CT assessment of sealant penetration in different types of fissures in primary molars. 微ct对不同类型乳牙牙槽裂隙的充填效果评价。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e140934
Krasimir Hristov, Ralitsa Bogovska-Gigova, Nedana Georgieva
{"title":"Micro-CT assessment of sealant penetration in different types of fissures in primary molars.","authors":"Krasimir Hristov, Ralitsa Bogovska-Gigova, Nedana Georgieva","doi":"10.3897/folmed.67.e140934","DOIUrl":"https://doi.org/10.3897/folmed.67.e140934","url":null,"abstract":"<p><strong>Introduction: </strong>Sealants prevent the development of dental caries by forming a protective barrier that reduces bacterial growth and food retention. The morphology of the pits and fissures and the material of the sealant can affect the depth to which it penetrates into the fissures and the longevity and durability of the sealant.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SEM and elemental analysis evaluation of the working surface of instruments from two different nickel titanium rotary file systems. 两种不同镍钛旋转锉系统的仪器工作表面的扫描电镜和元素分析评价。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e127609
Hachko Giragosyan, Ivan Filipov, Emiliya Simeonova, Nikolay Zahariev, Stela Kasabova
{"title":"SEM and elemental analysis evaluation of the working surface of instruments from two different nickel titanium rotary file systems.","authors":"Hachko Giragosyan, Ivan Filipov, Emiliya Simeonova, Nikolay Zahariev, Stela Kasabova","doi":"10.3897/folmed.67.e127609","DOIUrl":"https://doi.org/10.3897/folmed.67.e127609","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the present study was to evaluate the surface changes in two different systems of rotary instruments before and after use by means of scanning electron microscopy (SEM) and energy dispersive analysis (EDA).</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inappropriate polypharmacy during the COVID-19 pandemic: impact, challenges, and solutions - a narrative review. 2019冠状病毒病大流行期间不适当的多种用药：影响、挑战和解决方案——叙述性回顾。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e144169
Evelina Gavazova, Radiana Staynova, Daniela Grekova-Kafalova
{"title":"Inappropriate polypharmacy during the COVID-19 pandemic: impact, challenges, and solutions - a narrative review.","authors":"Evelina Gavazova, Radiana Staynova, Daniela Grekova-Kafalova","doi":"10.3897/folmed.67.e144169","DOIUrl":"https://doi.org/10.3897/folmed.67.e144169","url":null,"abstract":"<p><p>The COVID-19 pandemic has brought unprecedented challenges to healthcare systems worldwide, impacting various aspects of patient care. Polypharmacy, the concurrent use of multiple medications by a single patient, is a significant concern exacerbated by the pandemic. The dual threat of COVID-19 infection and polypharmacy for the same vulnerable group - the elderly and those with pre-existing multimorbidity - is particularly problematic, as polypharmacy has been shown to lead to suboptimal treatment outcomes in many chronic diseases. This comprehensive review explores the multifaceted issues surrounding polypharmacy during the COVID-19 pandemic, addressing its causes, consequences, and potential solutions.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trans-catheter mitral valve repair with MitraClip for mitral regurgitation. A case report of an unusual and acute complication of MitraClip migration in the left atrium. 二尖瓣返流经导管MitraClip修复。一个不寻常的和急性并发症的MitraClip迁移在左心房报告。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e127944
Despoina G Sarridou, Sophia Anastasia Mouratoglou, Christos Chamos, Theofilos Manos, Sokratis Tsagkaropoulos, Georgios Theodoros Karapanagiotidis
{"title":"Trans-catheter mitral valve repair with MitraClip for mitral regurgitation. A case report of an unusual and acute complication of MitraClip migration in the left atrium.","authors":"Despoina G Sarridou, Sophia Anastasia Mouratoglou, Christos Chamos, Theofilos Manos, Sokratis Tsagkaropoulos, Georgios Theodoros Karapanagiotidis","doi":"10.3897/folmed.67.e127944","DOIUrl":"https://doi.org/10.3897/folmed.67.e127944","url":null,"abstract":"<p><p>Transcatheter mitral valve repair with the MitraClip device has become an established therapeutic option for the treatment of symptomatic patients with mitral regurgitation and prohibitive surgical risk. Despite its safe profile when performed in experienced centers, complications such as MitraClip device detachment or migration into the left atrium can occur and pose a significant risk. We report a MitraClip device migration into the left atrium short after its placement in a patient with symptomatic mitral valve regurgitation and a history of previous coronary artery bypass grafting and aortic valve replacement.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing wound healing with synthetic hyaluronic acid injection in sutured incisions on BALB/c mice. 合成透明质酸促进BALB/c小鼠缝合切口愈合。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e130272
Elham Aryanfar, Mahdi Ghoncheh, Mohammad Afshar, Mahboobe Chahkandi, Elahe Allahyari, Mehri Shadi
{"title":"Enhancing wound healing with synthetic hyaluronic acid injection in sutured incisions on BALB/c mice.","authors":"Elham Aryanfar, Mahdi Ghoncheh, Mohammad Afshar, Mahboobe Chahkandi, Elahe Allahyari, Mehri Shadi","doi":"10.3897/folmed.67.e130272","DOIUrl":"https://doi.org/10.3897/folmed.67.e130272","url":null,"abstract":"<p><strong>Introduction: </strong>Hyaluronic acid has been shown to possess notable properties in wound healing, skin regeneration, and anti-inflammatory effects. The formation of scar tissue is a common and unintended phenomenon during the wound-healing process, potentially leading to diverse consequences for individuals.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural products in fascial burn treatment. 筋膜烧伤治疗中的天然产物。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e139352
Vanya N Anastasova, Elean I Zanzov, Aleksandar A Georgiev, Karina I Ivanova, Petar I Kiskinov, Elena S Krasteva, Dimitar A Dachev
{"title":"Natural products in fascial burn treatment.","authors":"Vanya N Anastasova, Elean I Zanzov, Aleksandar A Georgiev, Karina I Ivanova, Petar I Kiskinov, Elena S Krasteva, Dimitar A Dachev","doi":"10.3897/folmed.67.e139352","DOIUrl":"https://doi.org/10.3897/folmed.67.e139352","url":null,"abstract":"<p><strong>Introduction: </strong>Wound healing in burn patients presents a substantial clinical challenge. Various topical agents are available for the treatment of burn wounds. Facial burns present an increased challenge due to the complex management required, which impacts both physical recovery and psychological well-being.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Care of tracheostomized children. 气管造口术患儿的护理。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e143214
Stoyan Markov, Petya Markova
{"title":"Care of tracheostomized children.","authors":"Stoyan Markov, Petya Markova","doi":"10.3897/folmed.67.e143214","DOIUrl":"https://doi.org/10.3897/folmed.67.e143214","url":null,"abstract":"<p><p>Tracheotomy is an emergency surgical procedure that first appeared and was developed in ancient times. Surgical techniques for tracheotomy have been perfected in modern times, and in adults it is one of the most common surgical procedures performed in emergency departments and intensive care units worldwide.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral salt wasting syndrome in a patient who suffered a gunshot traumatic head injury: a case report. 脑盐消耗综合征患者遭受枪伤创伤头部：一个病例报告。
Folia medica Pub Date : 2025-02-24 DOI: 10.3897/folmed.67.e130280
Alejandro Rojas-Urrea, Daniela Arias-Mariño, Lorena García-Agudelo, Ivan Camilo Gonzalez-Calderon
{"title":"Cerebral salt wasting syndrome in a patient who suffered a gunshot traumatic head injury: a case report.","authors":"Alejandro Rojas-Urrea, Daniela Arias-Mariño, Lorena García-Agudelo, Ivan Camilo Gonzalez-Calderon","doi":"10.3897/folmed.67.e130280","DOIUrl":"https://doi.org/10.3897/folmed.67.e130280","url":null,"abstract":"<p><p>Cerebral salt wasting syndrome is described as a hyponatremic condition in the context of a central nervous system injury. It is caused by a renal loss of sodium, and the primary distinguishing factor among similar conditions, such as the syndrome of inappropriate antidiuretic hormone secretion, is a reduction in the extracellular fluid volume. We describe here the case of a young adult who suffered brain injuries as a result of a gunshot and developed cerebral salt wasting syndrome during his in-hospital stay. Any type of cerebral attack can lead to hyponatraemic syndrome, but the most common are subarachnoid hemorrhages and neurological and meningeal tuberculosis infections. Treatment of the cerebral salt wasting syndrome leads to both hypovolemia and hyponatremia correction. The first line of management included hydric reposition with saline solution, either isotonic or hypertonic, depending on the severity of the symptoms.</p>","PeriodicalId":12415,"journal":{"name":"Folia medica","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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