Food Science and Human Wellness最新文献_第5页

A wheat germ-rich diet preserves bone homeostasis by regulating gut microbiota and plasma metabolites in aged rats 富含小麦胚芽的饮食通过调节老年大鼠的肠道微生物群和血浆代谢物来保护骨稳态

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250040

Luanfeng Wang , Zebin Weng , Tong Chen , Yu Li , Ling Xiong , Haizhao Song , Fang Wang , Xiaozhi Tang , Bo Ren , Xuebo Liu , Xinchun Shen

{"title":"A wheat germ-rich diet preserves bone homeostasis by regulating gut microbiota and plasma metabolites in aged rats","authors":"Luanfeng Wang , Zebin Weng , Tong Chen , Yu Li , Ling Xiong , Haizhao Song , Fang Wang , Xiaozhi Tang , Bo Ren , Xuebo Liu , Xinchun Shen","doi":"10.26599/FSHW.2023.9250040","DOIUrl":"10.26599/FSHW.2023.9250040","url":null,"abstract":"<div><div>Bone loss caused by ageing has become one of the leading health risk factors worldwide. Wheat germ (WG) is consists of high amounts of bioactive peptides, polyunsaturated fatty acids, and dietary fibre. Currently, WG has been proven to possess strong antioxidant and anti-inflammatory properties. We recently explored the beneficial effects and relevant mechanisms of a WG-rich diet (2.5 % and 5 % WG, <em>m</em>/<em>m</em>) on bone homeostasis in aged rats. Our results showed that 5 % WG supplementation for 12 months effectively attenuated ageing-induced microstructural damage and differentiation activity changes in the femur. The 5 % WG supplementation also significantly increased the levels of total antioxidant capacity (T-AOC), glutathione peroxidase (GSH-Px) (<em>P <</em> 0.01), and superoxide dismutase (SOD) (<em>P <</em> 0.05), and decreased inflammatory cytokine levels (tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6)) (<em>P <</em> 0.01). Furthermore, the WG-rich diet reshaped the composition of the gut microbiota, enhancing short-chain fatty acids (SCFAs)-producing microbes and reducing inflammation-related microbes. In addition, metabolomics analysis showed that 5 % WG supplementation improved plasma metabolites related to bone metabolism. Conclusively, our study purports long-term WG-rich diet may preserve bone homeostasis by regulating gut microbiota and plasma metabolites in aged rats.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3582-3594"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140464390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China 高血压和植物性膳食模式与认知障碍的关系：中国全国队列研究

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250037

Fang Liang , Jialin Fu , Gabrielle Turner-McGrievy , Yechuang Wang , Kai Ding , Jing Zeng , Justin B Moore , Rui Li

{"title":"Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China","authors":"Fang Liang , Jialin Fu , Gabrielle Turner-McGrievy , Yechuang Wang , Kai Ding , Jing Zeng , Justin B Moore , Rui Li","doi":"10.26599/FSHW.2023.9250037","DOIUrl":"10.26599/FSHW.2023.9250037","url":null,"abstract":"<div><div>This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet (PBD) patterns may modify the association. We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey (2011−2018). Cognitive function was assessed by the Mini-mental State Examination (MMSE), and cognitive impairment was defined as an MMSE score below 18 points. Diet patterns were assessed using the overall plant-based diet index (PDI), healthful plant-based diet index (hPDI), and unhealthful plant-based diet index (uPDI) derived from a simplified food frequency questionnaire (FFQ). Blood pressure was measured through physical examination. Cox proportional hazard regression and restricted cubic spline were performed. Participants with hypertension had an increased risk of cognitive impairment compared with normal group. The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI, among participants with lower hPDI than those with higher hPDI, and among participants with higher uPDI than those with lower uPDI. A healthful PBD pattern may attenuate hypertension-induced cognitive impairment, while an unhealthful PBD pattern may exacerbate hypertension-induced cognitive impairment in elderly. Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3544-3552"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140465920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation into IgG/IgE binding capacity and gut microbiota of digestion products derived from glycated ovalbumin 糖化卵清蛋白消化产物的 IgG/IgE 结合能力和肠道微生物群调查

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250045

Jihua Mao , Yanhong Shao , Hui Wang , Jun Liu , Zongcai Tu

{"title":"Investigation into IgG/IgE binding capacity and gut microbiota of digestion products derived from glycated ovalbumin","authors":"Jihua Mao , Yanhong Shao , Hui Wang , Jun Liu , Zongcai Tu","doi":"10.26599/FSHW.2023.9250045","DOIUrl":"10.26599/FSHW.2023.9250045","url":null,"abstract":"<div><div>Gut microbiota plays an important role in food allergy. The immunoglobulin G (IgG)/immunoglobulin E (IgE) binding capacity and human gut microbiota changes of digestion products derived from glycated ovalbumin (OVA) were investigated. Gastrointestinal digestion effectively destroyed the primary structure of glycated OVA, resulting in a significantly higher digestibility than gastric digestion, and more abundant peptides < 3 kDa. Moreover, gastric and gastrointestinal digestion products have different fluorescence quenching and red shift of fluorescence peaks, and possess different conformational structures. These changes resulted in a decrease in 28.7 % of the IgE binding capacity of gastrointestinal digestion products beyond that of pepsin. Moreover, gastrointestinal digestion products of glycated OVA increased significantly the proportion of <em>Subdoligranulum</em>, <em>Collinsella</em>, and <em>Bifidobacterium</em>. Therefore, gastrointestinal digestion products of glycated OVA altered human intestinal microbiota, reducing the risk of potential allergy.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3633-3641"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140468043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification and analysis of immunological activity of two isoforms of tropomyosin in Alectryonella plicatula 鉴定和分析 Plicatula Alectryonella 中两种同工酶的免疫活性

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250050

Shiqiang Yang , Yexin Chen , Fei Huan , Xinrong He , Xiao Yun , Hong Liu , Guixia Chen , Guangming Liu

{"title":"Identification and analysis of immunological activity of two isoforms of tropomyosin in Alectryonella plicatula","authors":"Shiqiang Yang , Yexin Chen , Fei Huan , Xinrong He , Xiao Yun , Hong Liu , Guixia Chen , Guangming Liu","doi":"10.26599/FSHW.2023.9250050","DOIUrl":"10.26599/FSHW.2023.9250050","url":null,"abstract":"<div><div>Oyster, as a common aquatic food, play an important role in shellfish allergy. In this study, 2 tropomyosin (TM) isoforms TM-α and TM-β (TM-α/-β) in <em>Alectryonella plicatula</em> were identified. The sequences of 852 bp encoding 284 amino acids of TM-α/-β and 2 recombinant proteins were obtained, respectively. There were 12 amino acid differences between TM-α/-β. The results of immunological experiments indicated that TM-β had stronger immunobinding activity and immunoreactivity than those of TM-α. Structural analysis showed that TM-β had more <em>α</em>-helix and higher surface hydrophobicity than TM-α. Sequences and epitopes alignment with shellfish TMs revealed that amino acids of TM-β were more frequently recognized as IgE epitopes in other shellfish TMs than TM-α. Differences in structure and sequence account for the higher immunological activity of TM-β compared to TM-α. These findings provide a theoretical basis for enriching the understanding of shellfish TM and accurate diagnosis of allergic components.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3697-3707"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140469094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Goat milk-based infant formula regulates intestinal barrier function and promotes the production of short-chain fatty acids 以山羊奶为基础的婴儿配方奶粉可调节肠道屏障功能并促进短链脂肪酸的生成

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250002

Qingxue Chen , Ting Cao , Hongwei Tang , Linyi Zhou , Yuxuan Zheng , Jinju Cheng , Bailiang Li , Song Wang

{"title":"Goat milk-based infant formula regulates intestinal barrier function and promotes the production of short-chain fatty acids","authors":"Qingxue Chen , Ting Cao , Hongwei Tang , Linyi Zhou , Yuxuan Zheng , Jinju Cheng , Bailiang Li , Song Wang","doi":"10.26599/FSHW.2023.9250002","DOIUrl":"10.26599/FSHW.2023.9250002","url":null,"abstract":"<div><div>Infant formula (IF) based on cow milk and goat milk is a substitute food for infants who are underfed with human milk. In our previous study, we reported the composition and physicochemical stability of IF based on milk from cows and goats and a combination of both milks. Here, we investigated the effects of these 3 IFs on intestinal immunity and short-chain fatty acid production (SCFAs) using human microbiota-associated (HMA) mice and selected human milk as a positive control. The results showed that goat milk-based IF is associated with a functional immune advantage, due to the rise in the levels of immune-related cytokines interleukin (IL)-2 and IL-10, decreased levels of intestinal permeability markers <em>D</em>-lactic acid and endotoxin, and increased mRNA levels of intestinal tight junction proteins <em>occludin</em> and <em>claudin</em>. In addition, the intestine of mice fed with goat milk-based IF contained 12.06 μmol/g acetate, 2.42 μmol/g propionate, and 1.72 μmol/g butyrate, which reached 69 %, 79 %, and 60 % of the levels in human milk, respectively. Our results indicate that goat milk-based IF improves intestinal immune function and promotes the production of intestinal SCFAs.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3150-3158"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140465173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The gut-liver axis mechanismf of increased susceptibility to non-alcoholic fatty disease in female offspring rats with prenatal caffeine exposure 产前接触咖啡因的雌性后代大鼠对非酒精性脂肪疾病易感性增加的肠道-肝轴机制

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250035

Qian Wang , Xiaoqian Lu , Wen Hu , Cong Zhang , Kexin Liu , Kai Tong , Kaiqi Chen , Hui Wang

{"title":"The gut-liver axis mechanismf of increased susceptibility to non-alcoholic fatty disease in female offspring rats with prenatal caffeine exposure","authors":"Qian Wang , Xiaoqian Lu , Wen Hu , Cong Zhang , Kexin Liu , Kai Tong , Kaiqi Chen , Hui Wang","doi":"10.26599/FSHW.2023.9250035","DOIUrl":"10.26599/FSHW.2023.9250035","url":null,"abstract":"<div><div>Caffeine intake during pregnancy is common, while its effect on gut microbiota composition of offspring and the relationship with susceptibility to adult diseases remains unclear. This study aimed to confirm the effects of prenatal caffeine exposure (PCE) on the gut microbiota composition and its metabolites in female offspring rats, and to further elucidate its underlying mechanism and intervention targets in adult non-alcoholic fatty disease (NAFLD). The results showed that the gut microbiota of PCE female offspring at multiple time points from infancy to adolescence were significantly changed with depletion of butyric acid-producing bacteria, leading to a decrease in butyric acid in adulthood. It was also found that PCE female offspring rats were sensitive to NAFLD induced by a postnatal high-fat diet (HFD), which is mainly related to the enhancement of hepatic triglyceride synthesis function. Through mechanism exploration, we found that HFD further reduced the fecal and serum butyric acid levels in the PCE female offspring, which was significantly negatively correlated with hepatic <em>SREBP-1c/FASN</em> mRNA expression and triglyceride level. <em>In vivo</em> and <em>in vitro</em> experiments confirmed that sodium butyrate (NaB) supplementation could reduce hepatic lipid accumulation through MCT1/GPR109A-AMPK, thereby effectively decreasing the susceptibility to NAFLD in the PCE female offspring rats.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3522-3535"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140467978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lactobacillus gasseri CCFM1255 promotes peripheral estrogen synthesis in ovariectomized rats by modulating the gut microbiome and serum metabolome 加塞乳杆菌 CCFM1255 通过调节肠道微生物组和血清代谢组促进卵巢切除大鼠外周雌激素的合成

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250016

Qian Chen , Haiqin Chen , Jianxin Zhao , Wei Chen , Gang Wang

{"title":"Lactobacillus gasseri CCFM1255 promotes peripheral estrogen synthesis in ovariectomized rats by modulating the gut microbiome and serum metabolome","authors":"Qian Chen , Haiqin Chen , Jianxin Zhao , Wei Chen , Gang Wang","doi":"10.26599/FSHW.2023.9250016","DOIUrl":"10.26599/FSHW.2023.9250016","url":null,"abstract":"<div><div>The decline in ovarian estrogen production is known to have detrimental health consequences and negatively affect the quality of life in menopausal women. Increasing estradiol levels is key to preventing disease in menopausal women. In this study, <em>Lactobacillus gasseri</em> CCFM1255 isolated from healthy infants was found to have a positive effect on estradiol production in ovariectomized rats. CYP19, the key enzyme catalysing the conversion of androgens into estrogens, was upregulated in adipose tissue upon CCFM1255 treatment. Untargeted metabolome analysis and targeted metabolite detection were used to identify the key metabolites altered by CCFM1255 treatment. CCFM1255 treatment significantly improved the serum concentration of glutamine (Gln). A significantly positive correlation was observed between serum Gln and estradiol concentrations. CCFM1255 treatment reshaped the structure of the gut microbiome, which was correlated with certain changes in serum metabolite concentrations. These results indicate that the provision of CCFM1255 as a dietary supplement may be an effective strategy to alleviate menopausal symptoms by increasing circulating estradiol.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3301-3310"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140468224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of solid-phase extraction and gas chromatography-mass spectrometry (SPE-GC-MS) in resolution of metabolism pattern of higher alcohols in rat plasma SPE-GC/MS 在解析大鼠血浆中高级醇代谢模式中的应用

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250033

Yufei Liu , Xiaonian Cao , Zhilei Zhou , Qingxi Ren , Zhongwei Ji , Min Gong , Yuezheng Xu , Weibiao Zhou , Shuguang Chen , Jian Mao

{"title":"Application of solid-phase extraction and gas chromatography-mass spectrometry (SPE-GC-MS) in resolution of metabolism pattern of higher alcohols in rat plasma","authors":"Yufei Liu , Xiaonian Cao , Zhilei Zhou , Qingxi Ren , Zhongwei Ji , Min Gong , Yuezheng Xu , Weibiao Zhou , Shuguang Chen , Jian Mao","doi":"10.26599/FSHW.2023.9250033","DOIUrl":"10.26599/FSHW.2023.9250033","url":null,"abstract":"<div><div>Higher alcohols are key factors affecting sensory quality and post-drinking comfort of alcoholic beverages. A strategy combining solid-phase extraction and gas chromatography-mass spectrometry (SPE-GC-MS) was established to analyze the metabolism pattern of higher alcohols in rat plasma after gavage of 4 common alcoholic beverages including huangjiu, baijiu, wine and brandy. 7 mL of dichloromethane was determined as the optimal extraction condition, and 8 higher alcohols were precisely quantified with detection limits of 1.82−11.65 μg/L, recoveries of 89.07 %−110.89 % and fine repeatability. The fastest absorption and elimination rates of plasma total higher alcohols were observed in baijiu and huangjiu group, respectively, and the highest peak concentration was found in brandy group. Additionally, the metabolic rate of plasma isoamyl alcohol in huangjiu group was faster than that in wine group at the same intragastric administration dosage. This study may provide potential insight for evaluation of alcoholic beverage quality.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3501-3510"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140469307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural identification and antioxidative activity evaluation of flaxseed lignan macromolecules: structure-activity correlation 亚麻籽木酚素大分子的结构鉴定和抗氧化活性评估：结构-活性相关性

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2023.9250009

Chen Cheng , Lei Wang , Xiao Yu , Fenghong Huang , Jing Yang , Fang Geng , Xiaoyang Xia , Xia Xiang , Shufang Xu , Qianchun Deng

{"title":"Structural identification and antioxidative activity evaluation of flaxseed lignan macromolecules: structure-activity correlation","authors":"Chen Cheng , Lei Wang , Xiao Yu , Fenghong Huang , Jing Yang , Fang Geng , Xiaoyang Xia , Xia Xiang , Shufang Xu , Qianchun Deng","doi":"10.26599/FSHW.2023.9250009","DOIUrl":"10.26599/FSHW.2023.9250009","url":null,"abstract":"<div><div>Flaxseed lignan macromolecules (FLM) are a class of important secondary metabolites in flaxseed, which have been widely concerned due to their biological and pharmacological properties, especially for their antioxidative activity. For the composition and structure of FLM, our results confirmed that ferulic acid glycoside (FerAG) was directly ester-linked with herbacetin diglucoside (HDG) or pinoresinol diglucoside (PDG), which might determine the beginning of FLM biosynthesis. Additionally, <em>p</em>-coumaric acid glycoside (CouAG) might determine the end of chain extension during FLM synthesis in flaxseed. FLM exhibited higher antioxidative activity in polar systems, as shown by its superior 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging capacity compared to the 2,2'-azinobis(3-ehtylbenzothiazolin-6-sulfnic acid) (ABTS) cation free radical scavenging capacity in non-polar systems. Moreover, the antioxidative activity of FLM was found to be highly dependent on its composition and structure. In particular, it was positively correlated with the number of phenolic hydroxyl groups (longer FLM chains) and inversely related to the steric hindrance at the ends (lower levels of FerAG and CouAG). These findings verified the potential application of FLM in non-polar systems, particularly in functional food emulsions.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3224-3235"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140465647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research advances on encapsulation of probiotics with nanomaterials and their repair mechanisms on intestinal barriers 纳米材料包裹益生菌及其对肠道屏障修复机制的研究进展

IF 5.6 1区农林科学

Food Science and Human Wellness Pub Date : 2024-11-01 DOI: 10.26599/FSHW.2022.9250246

Xiaochen Wang , Mengxi Yu , Jianming Ye , Ting Liu , Lijuan Jian , Xiaoyan Zheng , Yuan Wang , Wei Song , Yan’e Luo , Tianli Yue

{"title":"Research advances on encapsulation of probiotics with nanomaterials and their repair mechanisms on intestinal barriers","authors":"Xiaochen Wang , Mengxi Yu , Jianming Ye , Ting Liu , Lijuan Jian , Xiaoyan Zheng , Yuan Wang , Wei Song , Yan’e Luo , Tianli Yue","doi":"10.26599/FSHW.2022.9250246","DOIUrl":"10.26599/FSHW.2022.9250246","url":null,"abstract":"<div><div>Probiotics participate in various physiological activities and contribute to body health. However, their viability and bioefficacy are adversely affected by gastrointestinal harsh conditions, such as gastric acid, bile salts and various enzymes. Fortunately, encapsulation based on various nanomaterials shows tremendous potential to protect probiotics. In this review, we introduced some novel encapsulation technologies involving nanomaterials in view of predesigned stability and viability, selective adhesion, smart release and colonization, and efficacy exertion of encapsulated probiotics. Furthermore, the interactions between encapsulated probiotics and the gastrointestinal tract were summarized and analyzed, with highlighting the regulatory mechanisms of encapsulated probiotics on intestinal mechanical barrier, chemical barrier, biological barrier and immune barrier. This review would benefit the food and pharmaceutical industries in preparation and utilization of multifunctional encapsulated probiotics.</div></div>","PeriodicalId":12406,"journal":{"name":"Food Science and Human Wellness","volume":"13 6","pages":"Pages 3095-3109"},"PeriodicalIF":5.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140465983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0