Experimental and Сlinical Urology最新文献

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Principles of therapy selection for enuresis in children and adolescents. 儿童和青少年遗尿症的治疗选择原则。
Experimental and Сlinical Urology Pub Date : 2022-09-25 DOI: 10.29188/2222-8543-2022-15-3-142-147
V. I. Morozov, R. Baybikov, A. Zakirov
{"title":"Principles of therapy selection for enuresis in children and adolescents.","authors":"V. I. Morozov, R. Baybikov, A. Zakirov","doi":"10.29188/2222-8543-2022-15-3-142-147","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-3-142-147","url":null,"abstract":"Introduction. The problem of enuresis to this day remains relevant primarily in connection with a decrease in the quality of life of both children, due to psychological discomfort, and their parents. The aim of the study was to select effective algorithms for the diagnosis and treatment of nocturnal enuresis in children and adolescents, taking into account the pathogenesis of the disease. Materials and methods. Children aged 5 to 15 years with a clinically confirmed diagnosis of enuresis were selected for the study. Depending on the clinical form of the disease, the children were divided into three groups. The first group included patients with the primary form of enuresis, the second-with secondary enuresis, and the third-with a mixed form of the disease. After an additional examination, all patients were assigned treatment based on their clinical group. Patients of the first clinical group were prescribed desmopressin as a treatment. In the second clinical group, treatment was carried out taking into account the level of damage to the nervous system. In the case of a suspected lesion of the cervical spine, electrophoresis was performed with a 1% solution of Euphyllini with an electrode applied to the cervical region. Nootropics and group B vitamins were prescribed for suspected cerebral lesions. In hyperexcitability syndrome, patients received Тenoten for children. In the third clinical group, treatment was carried out in two stages. The first stage corresponded to the protocol of treatment of the secondary form of enuresis, was carried out in a hospital setting. Further treatment was carried out on an outpatient basis in accordance with the recommendations for the treatment of the primary form of enuresis. Results. Positive dynamics was observed in all three clinical groups after the treatment. In 2.7% of children, a clinical cure was observed after the first course of therapy. 71.8% have a complete recovery after two courses of therapy. In 17.3% – after three courses of treatment. Conclusion. Principles of therapy selection for enuresis in children and adolescents require a comprehensive diagnosis and careful selection of therapy, depending on the pathogenetic form. The current control of therapy can be carried out by a pediatrician, and the intermediate results of treatment should be evaluated by a neurologist and a urologist. Hospitalization in a hospital is indicated in the case of the development of concomitant complications in the form of urinary tract infection, infectious and urodynamic disorders.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117233021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Results of a сomparative controlled trial to study the effectiveness of «Tubosan» in the complex therapy of patients with chronic bacterial prostatitis. 一项研究“土泊散”在慢性细菌性前列腺炎患者综合治疗中的有效性的比较对照试验的结果。
Experimental and Сlinical Urology Pub Date : 2022-09-25 DOI: 10.29188/2222-8543-2022-15-3-116-122
A. Smernitsky, S. Krasnyak
{"title":"Results of a сomparative controlled trial to study the effectiveness of «Tubosan» in the complex therapy of patients with chronic bacterial prostatitis.","authors":"A. Smernitsky, S. Krasnyak","doi":"10.29188/2222-8543-2022-15-3-116-122","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-3-116-122","url":null,"abstract":"Introduction. The high frequency of recurrence of chronic bacterial prostatitis may be due to the weakening of local and systemic immunity. This determines the need for immunotropic therapy in this disease. Target. To evaluate the effectiveness of «Tubosan» in the complex therapy of chronic bacterial prostatitis. Materials and methods. A comparative controlled cohort study was conducted. The study included 60 men with a microbiologically confirmed diagnosis of chronic bacterial prostatitis. The main group received antibiotic therapy in combination with «Tubosan». Control - only antibiotic therapy. The duration of treatment in both groups was 28 days. All patients underwent an IPSS questionnaire, microscopy, and culture of prostate secretion. Results and discussion. All patients of both groups showed complete eradication of pathogens according to the results of seeding of the secret of the prostate gland. In patients of the main group, a more pronounced decrease in symptoms was observed compared with the control. The sum of points on the IPSS scale before and after treatment in the main group was 21,9±1.3 vs 8.7±2.2, in the control group - 22.2±10.3 vs 10.3±1.4 points, respectively ( p<0.001). In the main group, there was a more significant decrease in the inflammatory process in the prostate. The average number of leukocytes in the field of view in the main group before and after treatment was 101.0±23.2 vs 5.2±1.3 cells (p<0.001), in the control group 101.6±21.5 vs 16.8±6.2 cells (p<0.001), respectively. After treatment, both groups showed a statistically significant improvement in the quality of life of patients, as assessed by the answer to question 7 of the IPSS questionnaire. In the main group, the average score on question No. 7 before and after treatment was 3.9±0.6 vs 1.8±0.5 points, respectively (p<0.001) 3.9±0.6 points vs 2.3±0.4 points, respectively (p<0.001). Conclusion. «Tubosan» can be used as an immunotropic agent in the complex therapy of chronic bacterial prostatitis to improve treatment outcomes","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130529808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Modern approaches to the treatment of chronic bacterial prostatitis. 慢性细菌性前列腺炎的现代治疗方法。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-130-139
M. Katibov, M. Alibekov
{"title":"Modern approaches to the treatment of chronic bacterial prostatitis.","authors":"M. Katibov, M. Alibekov","doi":"10.29188/2222-8543-2022-15-2-130-139","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-130-139","url":null,"abstract":"Introduction. The main treatment option for chronic bacterial prostatitis (CBP) is antimicrobial therapy. However, in connection with the steady increase in resistance to antimicrobial drugs and the high rate of failure in the treatment of such patients, it seems relevant to study new approaches to the treatment of this disease. Materials and methods. The review is based on articles published over the past 10 years (2011-2021) in scientific peer-reviewed journals included in the PubMed databases (https://www.ncbi.nlm.nih.gov/pubmed/) and the Scientific Electronic Library Elibrary.ru (https://elibrary.ru/). The search was carried out for the following keywords: «prostatitis», «chronic prostatitis», «chronic bactrial prostatitis», «chronic infectious prostatitis». At the first stage, 477 sources were found that were relevant to the topic of the review, of which 70 articles were selected for the final version of the review. Results. Oral antibiotic therapy remains the mainstay of treatment for CBP. There is a tendency towards an increase in resistance to traditionally used antimicrobial agents (fluoroquinolones, trimethoprim-sulfamethoxazole, etc.). In this regard, the possibilities of alternative antibacterial drugs (fosfomycin, etc.) and other methods of treatment are actively used and are being studied: direct administration of antimicrobial drugs into the prostate gland, chronic oral antibiotic prophylaxis, phage therapy and surgical interventions. An important role in the treatment of CBP is assigned to other pharmacological groups of drugs and non-drug methods of treatment (primarily physiotherapeutic methods). Conclusion. Many therapies that are used in addition to or instead of oral antibiotic therapy still cannot be recommended for use in general clinical practice, since there is currently a lack of sufficient evidence of their effectiveness and safety. Therefore, considering the existing problems of treating such patients, the need to continue studies to assess the possibilities of new promising approaches to the treatment of CBP remains relevant.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131837813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinoma of newborns is an unresolved problem of pediatric urology. 新生儿尿路瘤是儿科泌尿外科尚未解决的问题。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-162-166
S. Karavaeva, M. Kuchinsky, N. Filatova, M. A. Gopienko, D. Dobroserdov, E.A. Solntseva, E. Kondratyeva
{"title":"Urinoma of newborns is an unresolved problem of pediatric urology.","authors":"S. Karavaeva, M. Kuchinsky, N. Filatova, M. A. Gopienko, D. Dobroserdov, E.A. Solntseva, E. Kondratyeva","doi":"10.29188/2222-8543-2022-15-2-162-166","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-162-166","url":null,"abstract":"Introduction. Urinoma is a rare pathology of childhood, which manifests itself in the accumulation of urine in the perirenal space. In most cases, the cause of urinoma is an obstruction of the urinary system at some level (from the ureteropelvic segment to the urethra). The mechanism of the development of urinoma is damage of the collecting system of the kidney is related to an increase in intrarenal pressure above 35-40 cm of water column, while urine can accumulate both retroperitoneally and intraperitoneally or even in the pleural cavity by extravasation or as a result of damage of the parietal peritoneum. Due to the rare occurrence of this pathology, unified approaches to the treatment of patients with urinoma have not been developed. Materials and methods. On the basis of St. Petersburg GBUZ DGM KSTSVMT in the period from 2007 to 2020, 7 newborn patients with this diagnosis were treated. Of all the patients, 5 were transferred from the maternity hospital to the neonatal pathology department due to the prenatally diagnosed pathology of the urinary system. However, only one child was suspected of urinoma against the background of hydronephrosis. Results and discussion. The cause of urinoma in 1 case (14%) was obstructive megaureter, in 3 patients (43%) – hydronephrosis, in 2 (29%) – posterior urethral valve. In 1 patient (14%), the cause of the urinoma was not identified. It should be noted that cystic dysplasia of one or both kidneys was detected in 3 children against the background of the underlying pathology. Clinical manifestations of urinoma ranged from the absence of any symptoms (in 1 case) to the presence of a palpable mass in the abdominal cavity and lumbar region, which caused concern to the child (in 3 patients). CT was performed in 4 patients in order to clarify the nature, location, and possible connection of the cystic formation visualized by ultrasound with the collecting system or the kidney parenchyma. The tactics of treating urinoma were different depending on the specific case. Open intervention was required in 6 children (86%). Findings. The rarity of such a pathology as urinoma leads to the lack of a single tactic for its diagnosis and treatment. Applied methods of visual determination of perirenal accumulation of urine, such as ultrasound and CT, can not always help to reliably differentiate urinoma from a kidney/abdominal cyst or severe hydronephrosis. In most cases, preference is given to puncture techniques and radical treatment of the underlying uropathy.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132706853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal infarction. Analysis of 12 cases of acute renal artery occlusion. 肾梗塞。急性肾动脉闭塞12例分析。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-38-44
I. E. Mamaev, G.Sh. Saipulaev, K. V. Stepanenko, S. Kotov
{"title":"Renal infarction. Analysis of 12 cases of acute renal artery occlusion.","authors":"I. E. Mamaev, G.Sh. Saipulaev, K. V. Stepanenko, S. Kotov","doi":"10.29188/2222-8543-2022-15-2-38-44","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-38-44","url":null,"abstract":"Introduction. Kidney infarction (KI) is a rare condition that most often develops as a result of renal artery thromboembolism and causes complete or partial loss of renal function. The diagnosis of this pathology is challangable. Objective. To analyze the features of diagnosis, clinical, laboratory and instrumental characteristics of renal infarction. To assess delayed changes in the renal parenchyma in patients with renal infarction. Materials and methods. Retrospective analysis of data from 12 patients with KI who were admitted to V.M. Buyanov Moscow City Clinical Hospital from 2018 to 2021 and consequent prospective analysis of the results of examination of these patients between 2 and 34 months after KI were done. Result. The mean age of the patients was 60,4 years. Eight patients were admitted to the hospital with surgical diagnoses. None of the patients was correctly diagnosed in the first 12 hours from the onset of the disease. Seven patients had atrial fibrillation. The most informative diagnostic method was contrastenhanced renal computed tomography (CT) scan. The average lactate dehydrogenase (LDH) level was 1563,4 U/L, creatinine - 149,5 μmol/L. Discussion. Evaluation of functioning parenchyma during the control examination showed that it volume was equal to volume of the parenchyma not involved in the infarction at the time of primary hospitalization. Delayed investigation also showed mild violation of the evacuation function on the affected side. Conclusions. Atrial fibrillation is the main risk factor for renal infarction development. Contrast-enhanced CT remains the most valuable method for detecting acute renal artery occlusion. Late diagnosis of the infarction is the main reason of futility of endovascular correction. It requires vigilance of urologists and surgeons in relation to this problem.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115058291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern methods of minimally invasive treatment of premature ejaculation. 早泄的现代微创治疗方法。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-110-118
Y. Mirkin, A. Nevsky
{"title":"Modern methods of minimally invasive treatment of premature ejaculation.","authors":"Y. Mirkin, A. Nevsky","doi":"10.29188/2222-8543-2022-15-2-110-118","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-110-118","url":null,"abstract":"Introduction. Premature (early) ejaculation is a common male sexual problem. Despite a significant number of proposed methods, there is still no consensus among doctors about the most effective methods of conservative and surgical treatment of this pathology. Materials and methods. The results of publications of domestic and foreign authors devoted to various approaches to the surgical treatment of premature ejaculation were analyzed: circumcision, injections of fillers into the glans penis, various techniques for performing selective dorsal neurotomy, injection of botulinum toxin into the bulbospongiosus muscle, radiofrequency neuromodulation of the dorsal nerve of the penis, selective cryoablation of the dorsal nerve of the penis. Results. The most controversial surgical techniques for the treatment of premature ejaculation. Indications for surgery, technical performance are still variable, and the results are difficult to predict. Selective dorsal neurotomy, radiofrequency ablation, and cryoablation seem promising. It is necessary to develop standard approaches to the selection of patients and the method of performing operations based on a sufficient number of clinical studies. Conclusion. Despite the sufficient number of proposed methods for the surgical treatment of premature ejaculation, it is necessary to standardize approaches to the selection of patients and the choice of surgical technique.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124096899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new method of anterior reconstruction of pelvic structures in robot-assisted radical prostatectomy for improving of early urinary continence. 机器人辅助根治性前列腺切除术中骨盆结构前路重建的新方法改善早期尿失禁。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-18-23
M. S. Mosoyan, D. Fedorov, E.S. Gilev
{"title":"A new method of anterior reconstruction of pelvic structures in robot-assisted radical prostatectomy for improving of early urinary continence.","authors":"M. S. Mosoyan, D. Fedorov, E.S. Gilev","doi":"10.29188/2222-8543-2022-15-2-18-23","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-18-23","url":null,"abstract":"Introduction. Prostate cancer is one of the most common oncological diseases in men. Robot-assisted radical prostatectomy is associated with better urinary continence, compared with open and laparoscopic technique. Their oncologic outcomes are comparable. However, urinary incontinence after this surgery remains a challenge. Aim. To present a new technique of anterior reconstruction of pelvic structures during robot-assisted radical prostatectomy and evaluate its efficacy and safety. Materials and methods. We evaluated the results of treatment of 50 patients after robot-assisted radical prostatectomy for localised prostate cancer. They treated during the period from November 2020 till June 2021 in one medical centre. All surgeries were performed using transperitoneal access with anatomical-sparing technique. The anterior reconstruction of pelvic structures was performed with endopelvic fascia. All patients were informed about the study and signed the consent. The main perioperative parameters were assessed, as well as early oncological and functional outcomes. Evaluation the results of immediate and early urinary continence was carried out on the basis of questionnaire data. Results. The mean operative time was 140 min (110–170 min), mean console time was 72,5 min (45–100 min), the duration of the anterior reconstruction was 5,25 min (3,0–7,5 min). The average intraoperative blood loss was 50 ml (15–75 ml). There were no III-IV Clavien-Dindo complications. The 74% of patients were continent immediately after the surgery. The continent rate in a month after the surgery was 93%. Conclusion. This technique of robotic-assisted radical prostatectomy with anterior reconstruction is safe and effective. It does not increase the risk of complications and have no detrimental effect the oncological outcomes, while its early functional results are promising.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123824990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of the combined dietary supplement Uronext in women with recurrent cystitis: a clinical and microbiological study. 联合膳食补充剂Uronext治疗复发性膀胱炎的有效性:一项临床和微生物学研究。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-120-128
M. Slesarevskaya, I. Kuzmin, L. Kraeva, E. V. Smirnova
{"title":"The effectiveness of the combined dietary supplement Uronext in women with recurrent cystitis: a clinical and microbiological study.","authors":"M. Slesarevskaya, I. Kuzmin, L. Kraeva, E. V. Smirnova","doi":"10.29188/2222-8543-2022-15-2-120-128","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-120-128","url":null,"abstract":"Introduction. Introduction Antibacterial therapy is the main line of treatment for lower urinary tract infections (LUTIs). At the same time, not always satisfactory efficacy and the growing problem of antibiotic resistance of the main uropathogens determine the importance of finding alternative approaches. Many studies have confirmed the clinical efficacy of non-antibacterial therapy for LUTIs, however, a number of aspects of its pharmacological action remain unclear. Aim. Assessment of the clinical and microbiological effects of the dietary supplement «Uronext», containing D-mannose, vitamin D and cranberry extract, in women with recurrent LUTIs. Materials and methods. Under supervision were 67 women aged 18 to 65 years (mean 42.8±12.9 years) with recurrent LUTIs. By the time the study began, all patients were diagnosed with an exacerbation of cystitis. The study consisted of two parts: clinical and laboratory. During the first of these, patients were prescribed Uronext 1 sachet (2000 mg of D-mannose, Cran-Max (highly purified 100% natural cranberry extract with standardized activity (36 mg of proanthocyanidins) and 1 μg of vitamin D3) daily for 7 days and studied the dynamics of the symptoms of cystitis. The laboratory part included an assessment of the minimum inhibitory concentration (MIC), adhesion index, degree and time characteristics of the antimicrobial activity of Uronext against the main uropathogens. Results. Reception Uronekst was accompanied by a positive dynamic of the severity of symptoms of cystitis. The average total score of the «typical» section of the ACSS questionnaire decreased from the initial 8.27±2.05 on the 1st day of the study to 4.73±1.98 by the 3rd day and to 4.16±2.03 by the 7th day of the study. mu day of admission. By this time, 37 (55.2%) women indicated a significant improvement in their condition, and 7 (10.4%) women indicated the complete disappearance of symptoms. Initially, bacteriuria in a titer of ≥1000 CFU/ml was detected in 50 (74.6%) patients, while the antimicrobial activity of Uronext against isolated uropathogens was 48%. In vitro, the product had an antibacterial effect on both Gram-negative and Gram-positive uropathogens. At the same time, for gram-negative microorganisms, the MIC was 10 times lower than for gram-positive ones. In vitro antibacterial activity against uropathogens peaked 2 hours after the addition of Uronext to cell culture and persisted for at least 8 hours. A pronounced anti-adhesive effect of Uronext was revealed, leading to a decrease in the adhesion index to epithelial cells by 3.1–4.8 times, depending on the type of microorganisms. Conclusion. The appointment of a combined dietary supplement \"Uronext\" for patients with LUTI with exacerbation of cystitis seems to be a pathogenetically justified alternative to the use of antibiotics in this category of patients. The substances included in Uronext have a synergistic effect and contribute to its high microbiological efficiency","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123904680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Encrusted pyelitis. 镶嵌肾盂炎。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-66-73
I. E. Mamaev, K. Akhmedov, Y.V. Sushkova, S. Kotov
{"title":"Encrusted pyelitis.","authors":"I. E. Mamaev, K. Akhmedov, Y.V. Sushkova, S. Kotov","doi":"10.29188/2222-8543-2022-15-2-66-73","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-66-73","url":null,"abstract":"Introduction. Encrusted pyelitis is a rare clinical form of urolithiasis. It represents a formation of stones on the mucosa of collecting system because of violation of epithelial function. Encrusted pyelitis characterized by formation of multiple planar stones intimately soldered to the epithelial lining. Generally, accepted methods of surgical removal of stones is not effective in such case and different approach is required. Clinical case. Presented a clinical case of successful treatment of patient with encrusted pyelitis by chemolytic therapy. It carried out by irrigating the collecting system with a solution injected through nephrostomy drain. Discussion. Analysis of the literature on encrusted pyelitis shows that due to the rare occurrence of this pathology, there is no standardized approach to the treatment of this group of patients, and publications are limited to the analysis of clinical observations. A number of scientific papers confirmed effect of chemolytic therapy in these situations. Conclusion. A patient with encrusted pyelitis underwent several courses of chemolytic therapy with good results. Stone free status is achieved. It is important to note that chemolysis was effective only in relation to those stones that were on the way of the irrigation solution from the supply nephrostomy tube to the discharge one.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128800114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laser technologies in treatment of benign prostatic hyperplasia. 激光技术在治疗良性前列腺增生中的应用。
Experimental and Сlinical Urology Pub Date : 2022-06-25 DOI: 10.29188/2222-8543-2022-15-2-24-31
P. Bykov, A. A. Shiryaev, K. Kolontarev
{"title":"Laser technologies in treatment of benign prostatic hyperplasia.","authors":"P. Bykov, A. A. Shiryaev, K. Kolontarev","doi":"10.29188/2222-8543-2022-15-2-24-31","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-2-24-31","url":null,"abstract":"Introduction. Benign prostatic hyperplasia (BPH) is a common disease among men over 40 years old. Transurethral resection of the prostate has traditionally been considered the «gold standard» for surgical treatment of patients with BPH. The emergence and popularization of laser energy has led to the development of surgical technologies that can closely approach, and in some cases even exceed the effectiveness and safety of TURP. Materials and тethods. The data were searched in the PubMed, Web of Scince. databases of Google Scholar and the scientific electronic library eLibrary.RU using the following keywords: benign prostatic hyperplasia, surgical treatment; transurethral resection of the prostate; tulium laser; holmium laser; photoselective vaporization; GreenLight system; laser energy; cost-effectiveness. Among all currently available laser energies the greatest number of publications is devoted to the use of holmium and thulium energy for laser enucleation of the prostate (HoLEP and THuLEP). Results. The effectiveness of HoLEP has been well studied with papers on the use of this technique, including numerous randomized controlled trials. The safety and efficacy of surgical intervention in patients with a large prostate volume (>100 g) was confirmed in 2000. The efficacy of the procedure was comparable to open surgery, while perioperative morbidity was lower in the group of patients who underwent HoLEP. The Tulium laser has a wavelength of 2013 nm and a penetration depth of 0.25 mm, using water as an absorbing chromophore. Unlike the holmium laser, energy is released in a continuous visible mode. This energy for the treatment of patients with BPH was first used in 2015. ThuLEP was studied in a metaanalysis by Kyriazis et al. Four studies (two randomized studies comparing ThuLEP with TURP or HoLEP and two prospective cohort studies with a follow-up period of 3-24 months) were included in this work. The authors reported an 87% reduction in prostate volume, a significant change in Qmax and IPSS, on par with TURP. Conclusion. A large variety of laser surgical systems are currently available, differing in the types of laser energy used. Surgical treatment of BPH can be performed using any method of laser surgery. The most promising and safe method for BPH treatment is the use of tulium laser energy. However, there is insufficient data on the cost-effectiveness of laser technologies.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123112642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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