Experimental Brain Research最新文献_第4页

Exercise intensity improves performance on a spatial memory task. 运动强度可以提高空间记忆任务的表现。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-08-18 DOI: 10.1007/s00221-025-07142-4

Nicholas P Reinders, Gabriel Massarotto, Melissa Lacasse, Tom J Hazell, Michael E Cinelli

{"title":"Exercise intensity improves performance on a spatial memory task.","authors":"Nicholas P Reinders, Gabriel Massarotto, Melissa Lacasse, Tom J Hazell, Michael E Cinelli","doi":"10.1007/s00221-025-07142-4","DOIUrl":"10.1007/s00221-025-07142-4","url":null,"abstract":"Previous research suggests exercise improves spatial navigation abilities, though the effects of different exercise intensities on this cognitive function have not been explored. The current study assessed the influence of moderate-intensity and high-intensity acute exercise on spatial learning and memory, focusing on the acquisition of survey and route knowledge in young adults. Thirty-two participants (22.6 ± 1.7 y) were randomly assigned to one of three groups: (1) no-exercise control (n = 10); (2) moderate-intensity continuous training (MICT; 30 min at 75% maximal heart rate) (n = 12); (3) sprint interval training (SIT; 4 × 30 s all-out interspersed with 4 min recovery) (n = 10). Spatial navigation abilities were assessed using a virtual reality (VR) maze with evaluations at three time points: pre-exercise (TP1), immediately post-exercise (TP2), and 48 h post-exercise (TP3). Angular error (AE) was the primary measure of navigation accuracy. Both MICT and SIT groups exhibited improvements in spatial memory indicated by reductions in AE from TP1 to TP3 (p < 0.001) though the SIT group showed a greater reduction in AE compared to the MICT group (p = 0.039), suggesting a more pronounced benefit from higher-intensity exercise. The control group, however, showed no significant change in AE (p = 0.869), indicating no improvement in spatial memory without exercise intervention. The findings suggest that acute exercise, particularly at higher intensities, enhances spatial memory alongside with learning. It is possible that exercise can be used as a intervention to enhance cognitive functions, particularly spatial navigation.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 9","pages":"195"},"PeriodicalIF":1.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The recovery effect of acute aerobic exercise and music intervention on working memory under mental fatigue. 急性有氧运动与音乐干预对精神疲劳下工作记忆的恢复作用。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-08-18 DOI: 10.1007/s00221-025-07140-6

Weizhong Dong, Liang Hu, Qia Hu

引用次数: 0

Preparation duration shapes the goal-directed tuning of stretch reflex responses. 准备时间决定拉伸反射反应的目标定向调谐。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-08-18 DOI: 10.1007/s00221-025-07139-z

Robin Rohlén, Frida Torell, Michael Dimitriou

{"title":"Preparation duration shapes the goal-directed tuning of stretch reflex responses.","authors":"Robin Rohlén, Frida Torell, Michael Dimitriou","doi":"10.1007/s00221-025-07139-z","DOIUrl":"10.1007/s00221-025-07139-z","url":null,"abstract":"Stretch reflex responses counteract sudden perturbations, and modulation of reflex gains can facilitate voluntary movement. Recent studies suggest movement preparation includes goal-directed tuning of muscle spindles and an equivalent modulation of both short- and long-latency stretch reflex responses (SLR and LLR), as long as the preparatory delay between 'Cue' and 'Go' exceeds 250 ms. The current study aimed to clarify the minimal preparation time required for goal-directed modulation of SLR and LLR responses and to determine how such modulation progressively evolves with extended preparation. We recorded bipolar electromyographic signals of healthy participants to assess reflex responses to mechanical perturbations induced by a robotic manipulandum in the context of a delayed-reach task. Specifically, we examined how multiple preparatory delays (250, 300, 350, 400, 450, and 500 ms) impact the goal-directed modulation of SLR and LLR responses from the loaded or unloaded pectoralis major, anterior deltoid, and posterior deltoid muscles. We found that preparatory delays of 300 ms and 350 ms are sufficient for goal-directed tuning of SLR responses in the posterior deltoid and pectoralis muscles, respectively. Our results also suggest that unloading (i.e., antagonist loading) may facilitate both the earlier emergence and more robust expression of goal-directed SLR tuning. Goal-directed tuning of LLR responses emerged as early as 250 ms of preparation, and such tuning was robust against muscle load conditions, in line with previous findings. We observed no consistent increase in SLR tuning at preparation delays that extended beyond the required minimum, whereas such enhancement was observed at the LLR epoch. These findings clarify the temporal characteristics of goal-directed stretch reflex gains, which likely emerge through the interplay of multiple feedback mechanisms.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 9","pages":"198"},"PeriodicalIF":1.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vestibular contributions to balance control during stair negotiation versus walking and changes with aging. 前庭对楼梯行走和年龄变化的平衡控制的贡献。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-08-18 DOI: 10.1007/s00221-025-07141-5

Alexander Kern, Megan Elwood, Mike Vakula, Youngwook Kim, Eadric Bressel, Christopher J Dakin

{"title":"Vestibular contributions to balance control during stair negotiation versus walking and changes with aging.","authors":"Alexander Kern, Megan Elwood, Mike Vakula, Youngwook Kim, Eadric Bressel, Christopher J Dakin","doi":"10.1007/s00221-025-07141-5","DOIUrl":"10.1007/s00221-025-07141-5","url":null,"abstract":"Falls on stairs become more likely with age, partly due to deterioration of the sensorimotor systems essential to balance. The vestibular system, critical for balance control, experiences significant deterioration losing up to 40% of its motion-sensing hair cells by age 70. Signal transmittance also appears to increasingly act like a low-pass filter with age, due to several potential mechanisms. This study aimed to explore the vestibular contributions to balance control during stair negotiation to determine if aging increases reliance on low-frequency vestibular signals similar to standing during dynamic tasks. We hypothesized that older adults would exhibit greater low-frequency vestibular stimulus correlated responses than younger adults during walking and stair negotiation. Fifteen young and fifteen older adults performed stair ascent and stair descent, and treadmill walking while receiving electric vestibular stimulation. Vestibular stimulus correlated responses were quantified by measuring coherence and gain between a 0-25 Hz random waveform electric vestibular stimulus electromyographic activity in seven hip and leg muscles. We found older adults generally exhibited greater 'low' frequency (0-10 Hz) coherence relative to younger adults, whereas, younger adults exhibited greater coherence at higher frequencies (10-25 Hz). These findings not only provide evidence in support our hypothesis but also invite a broad discussion of alternative interpretations that may underlie the age-related shift in how different frequency vestibular signals influence muscle activity during dynamic balance tasks. More broadly, this study enhances our understanding of how aging affects thevestibular cues used during stair negotiation and walking.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 9","pages":"197"},"PeriodicalIF":1.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparable magnitude of haptic size adaptation aftereffects between younger and older people. 在年轻人和老年人之间的触觉大小适应后遗症的比较幅度。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-08-12 DOI: 10.1007/s00221-025-07144-2

Naoki Kuroda, Souta Hidaka, Wataru Teramoto

{"title":"Comparable magnitude of haptic size adaptation aftereffects between younger and older people.","authors":"Naoki Kuroda, Souta Hidaka, Wataru Teramoto","doi":"10.1007/s00221-025-07144-2","DOIUrl":"10.1007/s00221-025-07144-2","url":null,"abstract":"Perceptual information is processed independently in each hemisphere at some processing stages. This hemispheric asymmetry is reported to decrease in older people, including for haptic sensation. It has been demonstrated that a prolonged bimanual touch with objects of specific sizes induces a perceptual adaptation aftereffect called haptic size adaptation aftereffect: adaptation to a large/small object in each hand alters the subsequent perceived size of tested objects on the hands as smaller/larger than their actual size. Given that the decrease in hemispheric asymmetry reflects an enhanced inter-hemispheric and inter-hands interaction in older people, an age-related difference in the haptic size adaptation aftereffect could be observed in a bimanual adaptation situation. Our first experiment tested this possibility in the situation where adaptation and test were touched in both hands. We found a comparable magnitude of the aftereffect between younger and older people. In the second experiment, we introduced a situation where adaptation was performed in one hand, and tests were performed with either the adapted or non-adapted hand using a haptic-to-visual size matching task. The aftereffect was only clearly observed for the adapted hand in younger people. However, with some procedural modifications, the third experiment again showed a comparable magnitude of aftereffect between younger and older participants for both two-handed and one-handed adaptations on the adapted hand test in the haptic-to-visual size matching task. Our results suggest that similar perceptual and neural mechanisms, including interhemispheric interactions, underlie haptic size perception in younger and older people.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 9","pages":"193"},"PeriodicalIF":1.6,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between perceived maneuverability and compensatory eye movements under systematically varied time constants of ride-on machinery. 系统变化骑乘机械时间常数下，知觉机动性与代偿性眼动的关系。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-08-01 DOI: 10.1007/s00221-025-07135-3

Muhammad Akmal Mohammed Zaffir, Daisuke Sakai, Yuki Sato, Takahiro Wada

{"title":"Relationship between perceived maneuverability and compensatory eye movements under systematically varied time constants of ride-on machinery.","authors":"Muhammad Akmal Mohammed Zaffir, Daisuke Sakai, Yuki Sato, Takahiro Wada","doi":"10.1007/s00221-025-07135-3","DOIUrl":"10.1007/s00221-025-07135-3","url":null,"abstract":"Studies suggest that the vestibulo-ocular reflex (VOR), which is one of compensatory eye movements, exhibits greater stability during active motion compared to passive motion, and this effect may also apply to the operation of ride-on machinery. Moreover, one study suggested that experimentally manipulating the sense of agency (SoA), such as by introducing delays, can influence the stability of such eye movements. Although a preliminary investigation examined compensatory eye movements and perceived maneuverability under two distinct machine dynamics with a preserved SoA, it remains unclear how systematic variations in motion dynamics influence these factors. Therefore, this study aimed to investigate whether systematic variations in the dynamic properties of a ride-on machine, for which perceived maneuverability is modulated, influence the accuracy of operators' eye movements, focusing on continuous compensatory components, including visually enhanced VOR. Participants rode a yaw-rotational platform whose time constant from joystick input to motor torque was systematically manipulated. During the operation, eye movements were recorded while participants fixated on a visual target fixed to the Earth. After each condition, participants reported their perceived maneuverability and cognitive load. As the platform's time constant increased, maneuverability scores decreased, whereas cognitive load increased. Concurrently, the velocity accuracy of compensatory eye movements decreased. Perceived maneuverability was positively correlated with eye velocity gain and negatively correlated with velocity error. These findings suggest that perceived controllability and eye velocity accuracy are closely related under varying machine dynamics and that this relationship may inform the design of high-maneuverability ride-on machinery.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 8","pages":"192"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pericyte loss: a key factor inducing brain Aβ40 accumulation and neuronal degeneration in cerebral amyloid angiopathy. 周细胞丢失：脑淀粉样血管病中诱导脑a β40积累和神经元变性的关键因素。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-08-01 DOI: 10.1007/s00221-025-07134-4

Tao Liu, Weihong Guo, Ming Gong, Linyuan Zhu, Tingting Cao, Yilong Huang, Yunzhu Yang, Jiayi Chen, Canhong Yang, Shufen Zhang, Jiafa Zhang, Tianming Lü

{"title":"Pericyte loss: a key factor inducing brain Aβ40 accumulation and neuronal degeneration in cerebral amyloid angiopathy.","authors":"Tao Liu, Weihong Guo, Ming Gong, Linyuan Zhu, Tingting Cao, Yilong Huang, Yunzhu Yang, Jiayi Chen, Canhong Yang, Shufen Zhang, Jiafa Zhang, Tianming Lü","doi":"10.1007/s00221-025-07134-4","DOIUrl":"10.1007/s00221-025-07134-4","url":null,"abstract":"Cerebral amyloid angiopathy (CAA) is a cerebral small vessel disease common among the elderly. Pericyte loss is one of the earliest characteristics of CAA. Although pericyte loss correlates with neuronal loss, the molecular mechanisms by which pericyte loss contributes to neurodegeneration and CAA progression remain poorly understood. This study aimed to explore the role and the mechanism of pericyte loss in CAA using in vivo APP/PS1 mice models and an in vitro neurovascular unit (NVU) model. The findings showed that pericyte coverage and mRNA expression levels of pleiotrophin (PTN) were significantly decreased in the brain of APP/PS1 mice compared with wild-type (WT) littermate mice, while the amyloid-beta peptide (Aβ) load was elevated. Both pericyte loss and Aβ40 fibrils increased the permeability of the blood-brain barrier (BBB) and decreased secretion of PTN in the in vitro NVU model. Notably, pericyte reintroduction attenuated Aβ40-induced apoptosis in all SH-SY5Y neuroblastoma cells across experimental models, and pericytes reversed the apoptosis of SH-SY5Y cells induced by Aβ40 fibrils in these models. Furthermore, Aβ40 fibrils downregulated PTN secretion and induced pericyte apoptosis through activation of the p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) signaling pathways. Collectively, these data suggest that BBB disruption resulting from pericyte loss serves as an early pathological hallmark in CAA, promoting Aβ40 accumulation and neurodegeneration via MAPK-dependent pathways. These findings highlight the therapeutic potential of pericyte preservation strategies in CAA management.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 8","pages":"191"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fixating on a laser-projected point at a constant distance suppresses periodic eye movements and impairs balance control during cycling. 盯着恒定距离的激光投射点会抑制周期性眼球运动，并损害循环过程中的平衡控制。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-07-30 DOI: 10.1007/s00221-025-07133-5

Takashi Kojima, Katsuki Cho, Masahiro Kokubu

{"title":"Fixating on a laser-projected point at a constant distance suppresses periodic eye movements and impairs balance control during cycling.","authors":"Takashi Kojima, Katsuki Cho, Masahiro Kokubu","doi":"10.1007/s00221-025-07133-5","DOIUrl":"10.1007/s00221-025-07133-5","url":null,"abstract":"The visual field is influenced by movements of the body, head, and eye movements during self-motion. Therefore, compensatory eye movements that stabilize the visual field are crucial for perceptual-motor control. In cycling, a type of eye movement known as optokinetic nystagmus may help prevent visual blur and support the use of retinal flow for maintaining dynamic balance. This study aimed to examine the impact of visual environmental manipulation on dynamic balance control in cycling by altering gaze behavior. Participants cycled under three conditions and were instructed to ride as slowly as possible while staying on the path. In the control condition, they cycled along a striped path. In the laser condition, they cycled on the same path while fixating on a laser point projected 4 m ahead of the bicycle. In the monochrome condition, participants cycled along a plain white path. Each condition consisted of five trials. The results showed that the amplitude at the peak frequency of eye movements was significantly lower in the laser condition compared to the control and monochrome conditions. In addition, the cycling distance and duration were significantly shorter in the laser condition compared to the control condition. There were no significant differences in eye movements or cycling performance between the control and monochrome conditions. These results suggest that fixating on a laser point projected at a constant distance ahead suppresses the amplitude of eye movements and impairs balance control during cycling. Natural gaze behavior is likely to be an important factor for cycling safely.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 8","pages":"190"},"PeriodicalIF":1.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transfer of peripersonal space to a virtual body in young adults and exploration of adult age differences. 年轻人的个人空间向虚拟身体的转移及成人年龄差异的探索。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-07-25 DOI: 10.1007/s00221-025-07132-6

Dariusz O'Leary, Yichen Fan, Ina Schattenberg, Andrea Serino, Shu-Chen Li

{"title":"Transfer of peripersonal space to a virtual body in young adults and exploration of adult age differences.","authors":"Dariusz O'Leary, Yichen Fan, Ina Schattenberg, Andrea Serino, Shu-Chen Li","doi":"10.1007/s00221-025-07132-6","DOIUrl":"10.1007/s00221-025-07132-6","url":null,"abstract":"Peripersonal space (PPS) is known as the representation of the area around the body. Past research has shown that inducing a full-body illusion (FBI) can lead to PPS extending at the physical body location. However, it is unclear whether such illusions may also result in PPS transferring to a virtual body that is separate from the physical body. Furthermore, whether this effect may change over the course of natural aging is currently unknown. In three experiments, we investigated whether inducing an FBI using an avatar presented from a third-person perspective in virtual reality, results in PPS transferring to the avatar, and whether this effect differs between young (YAs; 18-29 years) and older adults (OAs; 65-83 years). We utilized a manipulation involving either synchronous or asynchronous stroking for FBI induction and assessed ratings of avatar ownership as a subjective indicator of embodiment. Meanwhile effects on PPS were measured by differences in multisensory facilitation within a visuo-tactile task. While we found significantly stronger ownership ratings for synchronous compared to asynchronous stroking in both YAs and OAs, this difference, as well as the degree of ownership, was significantly weaker for OAs. Moreover, while a distance-dependent modulation of multisensory facilitation reflecting PPS at the avatar's location was observed in two samples of YAs, this effect was absent in OAs. These findings suggest that PPS in YAs can transfer to an avatar in virtual reality, while age-related differences in susceptibility to the FBI might contribute to a lack of this effect in OAs.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 8","pages":"189"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144706930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diurnal variation and practice effects in saccade task performance. 扫视任务表现的日变化和练习效应。

IF 1.6 4区医学

Experimental Brain Research Pub Date : 2025-07-23 DOI: 10.1007/s00221-025-07131-7

Thomas Karantinos, Evi Kotsiou, Panagiota Drouza, Asimakis Mantas, Andrew J Anderson, Christoph Klein, Nikolaos Smyrnis

{"title":"Diurnal variation and practice effects in saccade task performance.","authors":"Thomas Karantinos, Evi Kotsiou, Panagiota Drouza, Asimakis Mantas, Andrew J Anderson, Christoph Klein, Nikolaos Smyrnis","doi":"10.1007/s00221-025-07131-7","DOIUrl":"10.1007/s00221-025-07131-7","url":null,"abstract":"Saccadic eye movement tasks have been widely used as a probe for measuring cognitive functions in healthy humans as well as in patients with neurological and psychiatric disorders. Circadian variation has been shown to affect multiple aspects of cognitive function especially executive function related to prefrontal cortex. The effects of diurnal variation in saccadic task performance and the dissociation of these effects from repetition or practice effects has not been adequately addressed. In the current study thirty healthy adults performed several saccadic eye movement tasks including visually guided saccades, antisaccades and countermanding saccades in three consecutive sessions. Participants were divided into three groups, with a different starting time of the sequence of the three sessions across groups (morning or afternoon or evening) to examine the effect of diurnal variation (time of day that the tasks were performed) separated from the effect of session repetition (practice effect). The results showed no effect of diurnal variation for all indexes of saccadic eye movement performance including accuracy (antisaccade and countermanding saccade tasks) speed (mean latency in all tasks) and stability (intra-subject standard deviation of latency in all tasks). In contrast, saccadic task repetition significantly improved accuracy, speed and stability of performance indicating the presence of practice effects in these tasks. Finally, linear mixed model analysis confirmed no interaction between diurnal variation and practice effects for all indexes of saccadic eye movement performance. In conclusion our study provides confirmation that saccadic task performance is not affected by diurnal variation related to circadian rhythms. In contrast, short term repetition of these tasks results in significant practice effects.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 8","pages":"188"},"PeriodicalIF":1.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12287220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0