Experimental Brain Research最新文献

Covariation of corticospinal excitability and the autonomous nervous system by virtual reality: the roller coaster effect.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-17 DOI: 10.1007/s00221-025-07015-w

Sidney Grosprêtre, Johanna Mathiot, Pauline Eon, Célia Ruffino

{"title":"Covariation of corticospinal excitability and the autonomous nervous system by virtual reality: the roller coaster effect.","authors":"Sidney Grosprêtre, Johanna Mathiot, Pauline Eon, Célia Ruffino","doi":"10.1007/s00221-025-07015-w","DOIUrl":"https://doi.org/10.1007/s00221-025-07015-w","url":null,"abstract":"Virtual Reality (VR) is a computer simulation of a three-dimensional environment, often displayed by means of a headset with integrated screens. While VR is known to consistently stimulate the autonomic nervous system, little is known regarding a possible effect on corticospinal excitability, or regarding a potential link between autonomous and voluntary nervous system modulations during VR. Fifteen healthy young participants were enrolled in a single-session experiment. They were seated in a comfortable chair and equipped with a VR headset that displayed a simulated roller coaster ride. Galvanic Skin Response (GSR) and cardiovascular markers (heart rate, heart rate variability) were monitored throughout the experiment. Corticospinal excitability was quantified by measuring the amplitude of the motor evoked potential (MEP), elicited by transcranial magnetic stimulation on the cortical representation of the right First Dorsal Interosseous (FDI) muscle. Results showed modulation in skin conductance, according to the phase of the roller coaster. Corticospinal excitability was increased during downhill and decreased during uphill phases, as compared to flat sections. The evolution of MEP/Mmax was concomitant and correlated to the evolution of GSR. No effect was observed on any of the cardiovascular markers. The present study showed that VR can be an efficient stimulus to modulate corticospinal excitability, even in the absence of a motor simulated situation. These data suggest a potential link between voluntary and autonomic nervous system regulation during VR of stressful situations. This study highlights the attractiveness of VR as an efficient stressor for both autonomous and motor systems, in sport training and in rehabilitation.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"69"},"PeriodicalIF":1.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can visual acceleration evoke a sensation of tilt?

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-17 DOI: 10.1007/s00221-025-07023-w

Laurence R Harris, Björn Jörges, Nils Bury, Meaghan McManus, Ambika Bansal, Robert S Allison, Michael Jenkin

{"title":"Can visual acceleration evoke a sensation of tilt?","authors":"Laurence R Harris, Björn Jörges, Nils Bury, Meaghan McManus, Ambika Bansal, Robert S Allison, Michael Jenkin","doi":"10.1007/s00221-025-07023-w","DOIUrl":"https://doi.org/10.1007/s00221-025-07023-w","url":null,"abstract":"Under the microgravity of the International Space Station, many of the normal processes that determine the perceptual upright on Earth are disrupted. For example, somatosensory cues are absent and an applied physical linear acceleration can provide an artificial \"gravity\" reference. Here, we hypothesized that visual linear acceleration could also be interpreted as an orientation cue in microgravity. Using virtual reality, we subjected twelve astronauts experiencing long-duration exposure to microgravity to visually simulated accelerating linear self-motion along a virtual corridor at 0.8 m•s- 2 (0.083 G) for 16s. They then adjusted a virtual ground plane to indicate whether they had changed their perceived orientation. Control experiments used visually simulated linear self-motion at a constant velocity and control experiments on Earth mirrored the experiments conducted in microgravity in both upright and supine postures. Contrary to our hypothesis, no significant perceptual tilts were induced on Earth or in microgravity. However, we did replicate earlier results that both microgravity exposure (in comparison to on Earth) and a supine posture (in comparison to a sitting upright posture) were associated with higher variability in judgements of upright. Our experiments failed to demonstrate that exposure to visual acceleration can evoke a sense of tilt in a stationary observer in the dark, either in microgravity or on Earth.N = 209.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"68"},"PeriodicalIF":1.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glioblastoma induced blood-brain barrier dysfunction via a paracrine mechanism that increases claudin-1 expression.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-17 DOI: 10.1007/s00221-025-07018-7

Brittany Schweiger, Forrest M Kievit

{"title":"Glioblastoma induced blood-brain barrier dysfunction via a paracrine mechanism that increases claudin-1 expression.","authors":"Brittany Schweiger, Forrest M Kievit","doi":"10.1007/s00221-025-07018-7","DOIUrl":"https://doi.org/10.1007/s00221-025-07018-7","url":null,"abstract":"Blood-brain barrier (BBB) disruption is a well-known phenomenon in glioblastoma (GBM). However, the mechanism driving BBB dysfunction in previously established vasculature at the invasive edge of GBM is still unknown. In this study, we aimed to determine if GBM paracrine signaling is sufficient to induce BBB dysfunction and identify changes in the tight junctions of the BBB. An in vivo U-87 MG xenograft model and an in vitro primary brain endothelial cell BBB model were established for barrier dysfunction monitoring. Immunofluorescent staining revealed significantly higher claudin-1 expression and significantly lower claudin-5 expression in the tumor vs. normal brain tissue of our in vivo model (p < 0.01). Additionally, claudin-1 expression co-localized with brain cell type markers for endothelium, pericytes, and microglia. In vitro exposure of brain microvascular endothelial cells to GBM conditioned media resulted in a significant decrease in transendothelial electrical resistance as well as delocalization of claudin-5 from the tight junctions. These results suggest GBM cells secrete factors capable of inducing changes in the tight junction proteins of the BBB and decreasing barrier integrity. Future studies will aim to identify the mechanism in which these changes occur.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"70"},"PeriodicalIF":1.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How language shapes emotional facial expression perception: an ERP study on the role of emotion word type.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-14 DOI: 10.1007/s00221-025-07013-y

Juan Zhang, Chenggang Wu, Yaxuan Meng

{"title":"How language shapes emotional facial expression perception: an ERP study on the role of emotion word type.","authors":"Juan Zhang, Chenggang Wu, Yaxuan Meng","doi":"10.1007/s00221-025-07013-y","DOIUrl":"https://doi.org/10.1007/s00221-025-07013-y","url":null,"abstract":"While it is widely acknowledged that emotion-label words (such as fear and sadness) play a crucial role in emotion perception, there is a limited understanding of how words laden with emotional meaning (e.g., virus, recovery), which do not explicitly refer to emotional states, influence emotion perception. This study conducted two experiments to explore how emotion-label words (Experiment 1) and emotion-laden words (Experiment 2) impact the perception of emotional facial expressions within the masked priming paradigm. Participants were tasked with assessing the valence of emotional facial expressions, and both behavioral and electrophysiological data were recorded. Behavioral results from Experiment 1 revealed that positive emotion-label words, as opposed to negative ones, elicited a priming effect. Emotional facial expressions led to a reduced Late Positivity Complex (LPC) when preceded by related emotion-label words compared to unrelated ones. However, Experiment 2 did not show any priming effects in behavioral and Event-Related Potential (ERP) measurements when emotion-laden words were used as primes. The combined results from both experiments underscore that only emotion-label words exert a priming effect on facial expression perception. This highlights the significance of specific emotion words, namely emotion-label words, such as fear and sadness, in shaping emotion perception. The influence of language on emotion perception appears to be restricted to words explicitly conveying emotion concepts, at least in the masked priming paradigm.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"66"},"PeriodicalIF":1.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of frequency domain features for the classification of evoked emotions using EEG signals.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-14 DOI: 10.1007/s00221-025-07002-1

Samannaya Adhikari, Nitin Choudhury, Swastika Bhattacharya, Nabamita Deb, Daisy Das, Rajdeep Ghosh, Souvik Phadikar, Ebrahim Ghaderpour

{"title":"Analysis of frequency domain features for the classification of evoked emotions using EEG signals.","authors":"Samannaya Adhikari, Nitin Choudhury, Swastika Bhattacharya, Nabamita Deb, Daisy Das, Rajdeep Ghosh, Souvik Phadikar, Ebrahim Ghaderpour","doi":"10.1007/s00221-025-07002-1","DOIUrl":"10.1007/s00221-025-07002-1","url":null,"abstract":"Emotion is a natural instinctive state of mind that greatly influences human physiological activities and daily life decisions. Electroencephalogram (EEG) signals created from the central nervous system are very useful for emotion recognition and classification. In this study, EEG signals of individuals are analyzed by the variational mode decomposition (VMD) for frequency domain features to recognize visual stimuli-based evoked emotions (happy, sad, fear). After cleaning EEG signals from artifacts, VMD is employed to decompose the signal into its respective intrinsic mode functions (IMFs). A sliding windowing approach is adopted to calculate the power distributions in each of the predefined frequency bands. The results reveal that extracting frequency domain features using a sliding window of 3 s significantly enhances the efficiency of analyzing induced emotions in subjects. The random forest model shows promising results in classifying various emotions, achieving an accuracy of 99.57% for validation and 99.36% for testing. Moreover, it is observed that the fifth IMF has a strong relationship with emotion elicited from visual stimuli. In addition, the features of the trained model are analyzed by Shapley additive explanations.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"65"},"PeriodicalIF":1.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11828826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental enrichment attenuates sevoflurane anesthesia-induced learning deficits in aged mice through regulating TTBK1 and phosphorylated Tau expression.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-14 DOI: 10.1007/s00221-025-07017-8

Xuenan Chang, Xiaoli Zhuang, Jingyu Feng, Yonghao Yu, Yang Yu

{"title":"Environmental enrichment attenuates sevoflurane anesthesia-induced learning deficits in aged mice through regulating TTBK1 and phosphorylated Tau expression.","authors":"Xuenan Chang, Xiaoli Zhuang, Jingyu Feng, Yonghao Yu, Yang Yu","doi":"10.1007/s00221-025-07017-8","DOIUrl":"https://doi.org/10.1007/s00221-025-07017-8","url":null,"abstract":"Perioperative neurocognitive disorders (PND) are a prevalent complication in elderly patients undergoing surgery with general anesthesia. Sevoflurane, a commonly used anesthetic, has been associated with cognitive impairment and neurotoxicity. In this study, we aim to explore the mechanisms through which sevoflurane impairs cognitive function in aged mice and hence identify potential therapeutic strategies. Female C57BL/6 J mice were treated with 2-h-daily Environmental enrichment (EE) for 4 weeks before being exposed to single 3% sevoflurane plus 60% oxygen inhalation for 2 h. WHI-P180, a TTBK1 inhibitor, was administered 5 min prior to anesthesia. Cognitive function, TTBK1, Tau p-Ser422, AT8 (Tau p-Ser202/p-Thr205), TNF-ɑ, IL-6, and IL-1β were measured. The results indicated that sevoflurane inhalation induced cognitive dysfunction, elevated TTBK1 expression and phosphorylated Tau levels, and increased inflammatory factors in the hippocampus of aged mice. However, EE treatment reduced elevated TTBK1, phosphorylated Tau, and inflammatory factor levels in the hippocampus. Additionally, EE alleviated cognitive impairment caused by sevoflurane in aged mice. Furthermore, WHI-P180 mitigated cognitive dysfunction by decreasing Tau phosphorylation and inflammatory cytokine levels in the hippocampus of aged mice. In conclusion, TTBK1 plays a crucial role in cognitive impairment induced by sevoflurane in aged mice, and EE mitigates sevoflurane-induced cognitive dysfunction by inhibiting TTBK1 and Tau protein phosphorylation in the hippocampus of old mice. These findings suggest that EE could be a potential therapeutic strategy for preventing or treating PND in elderly patients undergoing general surgery with sevoflurane anesthesia.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"67"},"PeriodicalIF":1.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Saikosaponins alleviate depression-like behaviors of chronic unpredictable mild stress exposed mice through ERK signaling pathway.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-12 DOI: 10.1007/s00221-025-07011-0

Min Chen, Min Li, Liwei Ma, Huiling Hou, Meiling Tang, Qiang Li

{"title":"Saikosaponins alleviate depression-like behaviors of chronic unpredictable mild stress exposed mice through ERK signaling pathway.","authors":"Min Chen, Min Li, Liwei Ma, Huiling Hou, Meiling Tang, Qiang Li","doi":"10.1007/s00221-025-07011-0","DOIUrl":"https://doi.org/10.1007/s00221-025-07011-0","url":null,"abstract":"Depressive disorder is the most common mental disorder with limited treatments. The aim of this study was to investigate the antidepressant effects of saikosaponins (SS) and its mechanism. The depression-like behaviors of chronic unpredictable mild stress (CS)-exposed mice were evaluated by sucrose preference test, forced swimming test (FST), and open field test (OFT). The proteome profiler mouse phospho-kinase array kit was used to reveal possible phosphorylated kinases and signaling nodes that SS treatment affected. TUNEL staining of brain tissues and protein levels of brain-derived neurotrophic factor (BDNF) and caspase-3 were combined to evaluate cell apoptosis. The U0126 was applied to pharmacologically inhibit ERK signaling pathway to verify the regulatory role of SS treatment on depression-like behaviors and cell apoptosis was achieved through ERK pathway. SS ameliorated chronic unpredictable mild stress‑induced depressive‑like behaviors by prominently increasing the sucrose preference, total traveling distance, standing number, and grooming number, and decreasing immobility time. SS also inhibited apoptosis of hippocampal neurons by down-regulating caspase-3 protein and up-regulating BDNF protein levels. SS treatment specifically up-regulated the phosphorylation of ERK through the proteome profiler mouse phospho-kinase array analysis. Moreover, the ERK inhibitor, U0126, pharmacological inhibited the phosphorylation levels of ERK induced by SS treatment, and further weakened the treatments of SS on depression-like behaviors and cell apoptosis. SS alleviates depression-like behaviors and protects neuron by activating the ERK signaling pathway, indicating that SS may be a potential therapeutic drug for treatment of depression.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"63"},"PeriodicalIF":1.7,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Standing balance responses and habituation to sinusoidal optic flow virtual reality perturbations.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-12 DOI: 10.1007/s00221-025-07014-x

Minal Ahuja, Trevor A Day, Nicholas D J Strzalkowski

{"title":"Standing balance responses and habituation to sinusoidal optic flow virtual reality perturbations.","authors":"Minal Ahuja, Trevor A Day, Nicholas D J Strzalkowski","doi":"10.1007/s00221-025-07014-x","DOIUrl":"https://doi.org/10.1007/s00221-025-07014-x","url":null,"abstract":"This study investigated the effects of prolonged virtual reality (VR) optic flow exposure on standing balance, focusing on how optic flow parameters influence balance responses and the potential for habituation. While short-term responses to optic flow are well-documented, the impact of extended VR immersion (up to 60 min) on balance remains poorly understood. Twenty healthy young adults were exposed to sinusoidal optic flow stimuli in a novel VR environment, with different velocities (0.1, 1, 10 m/s) and frequencies (0.125, 0.25, 0.5 Hz). Balance responses were assessed using a force plate to measure anteroposterior centre of pressure (CoP) velocity (AP-Vel) and mean power frequency (MPF). VR optic flow elicited significantly greater AP-Vel (P < 0.0001) and MPF (P < 0.0001) compared to non-VR eyes open conditions, with higher optic flow velocities and frequencies inducing greater balance responses (AP-Vel: P = 0.0322; MPF: P = 0.0027). Despite prolonged VR exposure, no evidence of habituation was observed within 90-second trials (P > 0.2110) or over the 40-60-minute experiment (P > 0.6724). Participants reported increased physical (P = 0.0010) and mental fatigue (P = 0.0005) by the end of the experiment, though this did not affect balance. These findings highlight the sensitivity of standing balance to VR optic flow parameters and the stability of balance responses over prolonged VR exposure, even with perceived fatigue. This research advances our understanding of sensory integration in postural control and informs the use of VR for research, rehabilitation, and entertainment.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"64"},"PeriodicalIF":1.7,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gamma-frequency transcranial alternating current stimulation over the left posterior parietal cortex enhances the long-term retention of associative memory.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-07 DOI: 10.1007/s00221-025-07009-8

Shunxiang Sun, Hiroki Annaka, Tomonori Nomura

{"title":"Gamma-frequency transcranial alternating current stimulation over the left posterior parietal cortex enhances the long-term retention of associative memory.","authors":"Shunxiang Sun, Hiroki Annaka, Tomonori Nomura","doi":"10.1007/s00221-025-07009-8","DOIUrl":"https://doi.org/10.1007/s00221-025-07009-8","url":null,"abstract":"Transcranial alternating current stimulation (tACS) has been reported to improve associative memory (AM) by modulating the frequency of neural oscillations in the brain; however, whether gamma-frequency (> 30 Hz) tACS in the left posterior parietal lobe (PPC) can enhance memory retention in AM remains unclear. This study aimed to investigate whether memory retention in AM could be improved after gamma-frequency tACS of the left PPC. We used a randomly assigned, double-blind, repeated-measures, sham-control design, in which 28 healthy adult participants were assigned to receive a single 20-min session of gamma-frequency (60 Hz) tACS or sham stimulation. The memory learning task consisted of studying and testing 50 unrelated word pairs three times on day 1. The number of correct responses in the cued recall task was measured at three time points: days 1, 7, and 28. The results revealed a significant difference in the number of correct responses between the interventions on day 7 and day 28. These data suggest that gamma-frequency tACS stimulation of the left PPC enhances the long-term retention of AM in healthy adults.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"62"},"PeriodicalIF":1.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Attention and control of posture: the effects of light touch on the center-of-pressure time series regularity and simple reaction time task.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-02-06 DOI: 10.1007/s00221-025-07007-w

Anna Brachman, Justyna Michalska, Bogdan Bacik

{"title":"Attention and control of posture: the effects of light touch on the center-of-pressure time series regularity and simple reaction time task.","authors":"Anna Brachman, Justyna Michalska, Bogdan Bacik","doi":"10.1007/s00221-025-07007-w","DOIUrl":"https://doi.org/10.1007/s00221-025-07007-w","url":null,"abstract":"The stabilizing influence of a light touch (LT) on a postural sway has been consistently shown in the literature, however there is still no consensus in what way attentional resources are used when adopting LT during standing. To better elucidate the underlying mechanisms we introduced additional feedback (LT), which seems to distracts from postural control, and verified it by center of pressure (COP) regularity level and simple reaction time task. 25 healthy students randomly performed eight postural tasks, four without (NoRT)/ four with simple reaction task (RT). COP displacements were measured on a force plate in two visual conditions: eyes open/closed and two sensory conditions: without (NoLT)/with light touch (LT). Participants were asked to consider the postural task as the primary task. Although simple reaction time did not differ between postural conditions (p > 0.05), LT decreased postural sway velocity in anteroposterior direction (p < 0.001, η2 = 0.86) and decreased standard deviation (p < 0.001, η2 = 0.91) in both, reaction and visual conditions. Interestingly, RT task modified subjects behavior in NoLT conditions and caused slower COP velocity (p < 0.001, η2 = 0.53) without changes in signal regularity. Results also showed a significant increase in irregularity during standing with LT (p < 0.001, η2 = 0.86) in both vision and reaction conditions, suggesting that the signal was more random. Current results suggests that providing LT enhance postural steadiness and also seem to redirect attention externally, as shown by increased signal irregularity. Hence, LT possibly reduce the attention invested in the postural task itself. A RT task can be not sensitive enough to detect such subtle changes.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 3","pages":"60"},"PeriodicalIF":1.7,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0