Experimental Brain Research最新文献

Medial septum deep brain stimulation enhances memory and hippocampal neurogenesis in the D-galactose induced rat model of aging: behavioral and immunohistochemical study. 内侧隔深部脑刺激可增强 D-半乳糖诱导衰老模型大鼠的记忆力和海马神经发生：行为和免疫组化研究。

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-18 DOI: 10.1007/s00221-025-07051-6

Ekaterine E Kipiani, Maia A Burjanadze, Manana G Dashniani, Nino C Chkhikvishvili, Temur L Naneishvili, Mariam R Chighladze, Barbare G Nozadze, Gela V Beselia

{"title":"Medial septum deep brain stimulation enhances memory and hippocampal neurogenesis in the D-galactose induced rat model of aging: behavioral and immunohistochemical study.","authors":"Ekaterine E Kipiani, Maia A Burjanadze, Manana G Dashniani, Nino C Chkhikvishvili, Temur L Naneishvili, Mariam R Chighladze, Barbare G Nozadze, Gela V Beselia","doi":"10.1007/s00221-025-07051-6","DOIUrl":"https://doi.org/10.1007/s00221-025-07051-6","url":null,"abstract":"One of the cardinal features of aging is brain aging, which manifests itself in impaired cognitive functions. Experimental data suggest that deep brain stimulation (DBS) can improve memory functions when stimulating specific brain regions. In present study we tested the hypothesis that medial septum (MS) DBS enhances memory function by modulating the hippocampal neurogenesis in the D-galactose (D-gal) induced rat model of aging. Rats were randomly assigned to four experimental groups: (1) control, (2) administration of D-gal, (3) administration of D-gal and electrode implantation and (4) administration of D-gal, electrode implantation and stimulation. Our results showed that MS DBS significantly enhanced the memory functions in an animal model of aging induced by D-gal administration, which impaired long-term spatial memory in the Morris water maze and impaired spatial and object novelty recognition memory in the open field. The immunohistochemical studies showed that in the Dentate Gyrus (DG) of rats with D-gal administration or D-gal combined with electrode implantation, the number of NeuN (neuronal nuclear antigen) or Doublecortin-immunopositive cells decreased (Doublecortin - a biomarker for the post-mitotic phase of cells); MS stimulation increases the number of these cells in the DG to levels comparable to the control group. Thus, MS-DBS restores the level of hippocampal neurogenesis. The present data demonstrate for the first time that chronic DBS of the MS restores memory functions in a D-gal-induced animal model of aging, and that one of the important underlying mechanisms is mediated by enhanced neurogenesis in the hippocampus.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"95"},"PeriodicalIF":1.7,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The synergistic effects of cycloserine and anodal tDCS: a systematic review and meta-analysis. 环丝氨酸和阳极 tDCS 的协同效应：系统综述和荟萃分析。

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-18 DOI: 10.1007/s00221-025-07038-3

Fernanda Cristina Poscai Ribeiro, July Samy Brasil, Diego Carneiro Vianna, Kleber Fernando Pereira, Felipe Fregni

{"title":"The synergistic effects of cycloserine and anodal tDCS: a systematic review and meta-analysis.","authors":"Fernanda Cristina Poscai Ribeiro, July Samy Brasil, Diego Carneiro Vianna, Kleber Fernando Pereira, Felipe Fregni","doi":"10.1007/s00221-025-07038-3","DOIUrl":"https://doi.org/10.1007/s00221-025-07038-3","url":null,"abstract":"This systematic review examines the synergistic effects of Cycloserine and anodal transcranial direct current stimulation (tDCS) on cortical excitability and clinical outcomes. tDCS, a non-invasive neuromodulation technique, modulates cortical excitability, potentially enhancing neuroplasticity. Cycloserine, a partial agonist at NMDA receptors, may potentiate tDCS effects by stabilizing receptor activity. A comprehensive database search identified five eligible studies focusing on healthy participants, with one involving patients with depression. Meta-analysis revealed that Cycloserine prolonged cortical excitability 60 min post-tDCS (SMD: 0.66, 95% CI: 0.05 to 1.27), with the greatest effect observed at a 100 mg dosage (SMD: 0.78, 95% CI: 0.26 to 1.31). Although this suggests a potential enhancement of tDCS efficacy, clinical improvements, such as in depression or motor learning, were not consistently significant across studies. Overall, while Cycloserine appears to extend tDCS-induced cortical excitability, more robust clinical trials are necessary to confirm its therapeutic benefits.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"94"},"PeriodicalIF":1.7,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The neural correlates of target and hand vision during movement planning and execution.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-16 DOI: 10.1007/s00221-025-07043-6

Darian T Cheng, Luc Tremblay, Krista Fjeld, Olave E Krigolson, Gordon Binsted

{"title":"The neural correlates of target and hand vision during movement planning and execution.","authors":"Darian T Cheng, Luc Tremblay, Krista Fjeld, Olave E Krigolson, Gordon Binsted","doi":"10.1007/s00221-025-07043-6","DOIUrl":"https://doi.org/10.1007/s00221-025-07043-6","url":null,"abstract":"In the current study, electroencephalographic (EEG) data was recorded to study the impact of hand and target visibility on neural processing during both the planning and execution of upper limb reaches. Prior to each movement, participants were informed if the hand and/or the target would be available in four conditions: (1) hand and target visible, (2) hand only, (3) target only, and (4) no hand, no target. Visual evoked potentials (VEPs) were assessed after target onset (i.e., prior to the reaching movement: P2), which revealed larger positive components when vision of the target was not going to be available during the reaching movement (i.e., hand only, no hand-no target) compared to when the target would be present (i.e., hand and target, target only). Further, the motor-related evoked potentials (MEPs) observed in relation to the reaching movement onset showed that a second negative peak generated during the execution of the reaching movement was significantly greater for reaches without vision of the hand, as compared to reaches with vision of the hand. Our results indicate a sequential importance of seeing the target and the hand, prior-to and during the movement, respectively. This work provides neurophysiological evidence to better understand the utilization of vision of the hand and target during goal-directed reaching.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"93"},"PeriodicalIF":1.7,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Considerations for tactile perceptual assessments: impact of arm dominance, nerve, location, and sex in young and older adults.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-15 DOI: 10.1007/s00221-025-07044-5

Emily M Tirrell, Nahid Kalantaryardebily, Anna C Feldbush, Lindsey Sydnor, Christopher Grubb, Kevin Parcetich, Netta Gurari

{"title":"Considerations for tactile perceptual assessments: impact of arm dominance, nerve, location, and sex in young and older adults.","authors":"Emily M Tirrell, Nahid Kalantaryardebily, Anna C Feldbush, Lindsey Sydnor, Christopher Grubb, Kevin Parcetich, Netta Gurari","doi":"10.1007/s00221-025-07044-5","DOIUrl":"10.1007/s00221-025-07044-5","url":null,"abstract":"Purpose: Intact tactile perception is essential to successfully interact with objects. While tactile examinations exist for capturing tactile impairments, recent investigations underscore that these examinations remain insufficient, particularly for adults following a neurological injury. To inform the design of improved tactile assessments, this study comprehensively captures factors that can influence tactile perception in young and older adults who are neurologically intact.Methods: We examined the impact of arm dominance (dominant/non-dominant), nerve (median/ulnar/radial), location (hand/elbow), and sex (male/female) on thresholds at which electrotactile stimuli could be consciously detected when applied to the skin in 20 young and 14 older right-arm dominant participants.Results: Significant differences depending on arm dominance were not found in young (p = 0.6781) or older (p = 0.2786) adults. Yet, the nerve tested did yield differing thresholds in young (p < 0.0001) and older (p < 0.0001) adults. In young adults, thresholds were less at the hand than elbow (p = 0.0031). In older adults, the average threshold was greater at the hand than elbow. Importantly, in older adults the threshold at the hand increased with age to a greater extent than at the elbow (p < 0.0001). Thresholds were greater in males than females in young adults (p = 0.0004), whereas no significant sex differences were observed in older adults (p = 0.2560).Conclusion: This work highlights the importance of addressing numerous factors and their interactions when assessing tactile perception (e.g., arm dominance, nerve, location, sex, age). Findings can inform the design of improved tactile assessments that more accurately capture why impairments arise, including following a neurological injury.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"92"},"PeriodicalIF":1.7,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of bilateral tDCS over left and right M1 produces asymmetric training and retention effects when learning a rhythmic bimanual task. 在学习有节奏的双臂任务时，在左右M1上应用双侧tDCS会产生不对称的训练和保持效果。

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-14 DOI: 10.1007/s00221-025-07045-4

Austin T McCulloch, David L Wright, John J Buchanan

{"title":"Application of bilateral tDCS over left and right M1 produces asymmetric training and retention effects when learning a rhythmic bimanual task.","authors":"Austin T McCulloch, David L Wright, John J Buchanan","doi":"10.1007/s00221-025-07045-4","DOIUrl":"10.1007/s00221-025-07045-4","url":null,"abstract":"Many motor skills require precise coordination between the arms to accomplish. The use of transcranial direct current stimulation (tDCS) has helped to reveal hemispheric contributions to bimanual skills. In this study, three bilateral montages were used to explore hemispheric contributions to a rhythmic bimanual skill: anode left M1/cathode right M1 (LARC), anode right M1/cathode left M1 (RALC), and sham. Stimulation lasted 20-minutes during training. Retention was examined 6-hr after training. Participants (n = 46) learned a bimanual 90° relative-phase pattern with a half-cycle movement amplitude goal of 12 cm per arm at self-selected movement frequencies. Greater coordination variability in the 90° pattern emerged early under RALC compared to LARC, with no difference in performance accuracy. Larger movement amplitudes emerged in training with LARC compared to sham but not compared to RALC. tDCS montage had no impact on coordination variability and accuracy of the 90° pattern after the 6-hr delay. Montage was associated with a delayed movement amplitude effect emerging in retention, with larger amplitudes in LARC compared to RALC and sham. The asymmetries observed across training and retention emerged from of an interaction between tDCS and the left-hemisphere's role in the control of bimanual movements in right-handed individuals.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"91"},"PeriodicalIF":1.7,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Joint examination of reflexive vertical saccades and small involuntary fixational saccades improves the classification of patients with progressive supranuclear palsy (PSP): a ROC study.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-13 DOI: 10.1007/s00221-025-07031-w

Wolfgang Becker, Olga Vintonyak, Jan Kassubek

{"title":"Joint examination of reflexive vertical saccades and small involuntary fixational saccades improves the classification of patients with progressive supranuclear palsy (PSP): a ROC study.","authors":"Wolfgang Becker, Olga Vintonyak, Jan Kassubek","doi":"10.1007/s00221-025-07031-w","DOIUrl":"10.1007/s00221-025-07031-w","url":null,"abstract":"A slowing of saccadic eye movements is one of the key symptoms of progressive supranuclear palsy and therefore represents a core functional domain of the current diagnostic criteria. However, there is considerable overlap between the saccade velocities of healthy people and patients in early stages. Therefore, a highly specific discrimination between patients and controls based on eye velocity often results in a considerable loss of sensitivity. Another symptom of progressive supranuclear palsy is a high frequency of square wave jerks formed by small involuntary fixational saccades. Using ROC analyses of 50 patients and 50 controls and focusing on points of 100 and 90% specificity or sensitivity, we investigated whether the velocity and gain data of visually guided reflexive saccades could be combined with each other and with parameters of fixational saccades to improve discriminability compared to considering saccade velocity alone. Both approaches were successful in patients with long disease duration but less so in cases of short duration. The displacement rate produced by square waves during fixation proved helpful because its frequency distributions in patients and controls had value ranges that were not shared by the two groups. This fact allowed an a priori classification of some subjects as either patients or controls. Modified ROC analyses using this a priori information are expected to work equally well in patients with short and long disease duration. In future studies it might be addressed if these methods can also improve the discrimination between PSP and other Parkinsonian disorders.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"90"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11906540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceptual decoupling in the sustained attention to response task is indeed unlikely: a reply to Shelat and Geisbrecht (in press). 持续注意与反应任务中的知觉解耦确实不太可能：对 Shelat 和 Geisbrecht（出版中）的答复。

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-12 DOI: 10.1007/s00221-025-07033-8

William S Helton

{"title":"Perceptual decoupling in the sustained attention to response task is indeed unlikely: a reply to Shelat and Geisbrecht (in press).","authors":"William S Helton","doi":"10.1007/s00221-025-07033-8","DOIUrl":"https://doi.org/10.1007/s00221-025-07033-8","url":null,"abstract":"Shelat and Geisbrecht (in press) challenge Bedi et al.'s (Exp Brain Rese 242(8):2033-2040 2024b) position that perceptual decoupling in the Sustained Attention to Response Task (SART) is unlikely. Instead they argue perceptual decoupling is likely in the SART and advocate for the SART's continued use in perceptual decoupling research. Shelat and Geisbrecht, however, are overlooking the extensive behavioral evidence that perceptual decoupling in the SART is indeed unlikely, including research by the researchers who originally developed the task demonstrating nearly 100% awareness of the task stimuli. The SART was developed to be a very short replacement for the long duration low Go, high No-Go target detection tasks used by sustained attention or vigilance researchers. While altering the response format in the SART to a high Go, low No-Go task indeed resulted in errors occurring reliably in a very short duration, the resulting SART has a substantial speed-accuracy trade-off. This causes immense confusion when interpreting performance in the SART. Furthermore, Shelat and Geisbrecht suggest DeBettencourt et al. (Nat Hum Behav 3(8):808-816, 2019) as a method improvement on the original SART, but ignore the entire point of the SART which was to be a short duration replacement for traditional vigilance tasks. The task utilized by DeBettencourt et al. (Nat Hum Behav 3(8):808-816, 2019) is as long in duration or longer than traditional vigilance tasks, but still is contaminated with a speed-accuracy trade-off, which makes untangling the underlying processes involved challenging. If researchers want to study sustained attention- perceptual decoupling, vigilance researchers have already figured out how to do this and the way to do this is not the SART.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"88"},"PeriodicalIF":1.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elicited emotion: effects of inoculation of an art style on emotionally strong images.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-12 DOI: 10.1007/s00221-025-07030-x

Amparo Caceres Gutierrez, Julián Tejada, Enrique García Fernández-Abascal

{"title":"Elicited emotion: effects of inoculation of an art style on emotionally strong images.","authors":"Amparo Caceres Gutierrez, Julián Tejada, Enrique García Fernández-Abascal","doi":"10.1007/s00221-025-07030-x","DOIUrl":"10.1007/s00221-025-07030-x","url":null,"abstract":"The objective of this research is to study how the application of the Convolutional Neural Network (CNN) artistic filter can be an alternative to mitigate the emotional response to photographs with strong emotional content published in Internet news. Van Gogh's artistic style was extracted through a CNN and inoculated with 64 IAPS images chosen to cover the entire emotional space. 140 university students of both sexes (70 men and 70 women) with an average age of 22 years, evaluated 128 stimuli, 64 original and 64 digitally inoculated, giving the appearance that they were painted with the artistic style of Van Gogh. For the evaluation of the stimuli, four groups were established under the conditions: 1 high arousal-positive valence, 2 negative valence-low arousal, 3 high arousal-negative valence and 4, low arousal, positive valence. The original images (OI) tended to produce less pleasant effects, while the images inoculated with filters made with CNN provoked reactions with a tendency to calm. The most significant changes in the emotional states are observed in the valence, the stimuli with the inoculation of the artistic style produces alterations with a tendency to pleasant effects. The averages of the comparisons of the dimensions valence and arousal of the OI and the CNN allow to show that there are differences in the emotional states, the results can permit the development of a methodology that, based on the inoculation of the artistic style of original paintings through CNN in emotionally strong images, a new image is created that replaces the strong images published in the Internet news.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"89"},"PeriodicalIF":1.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11903571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual categorisation of images of familiar objects based on their authenticity: an fMRI study.

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-10 DOI: 10.1007/s00221-024-06989-3

Grace A Gabriel, Cristina Simões-Franklin, Georgia O'Callaghan, John Stapleton, Fiona N Newell

{"title":"Visual categorisation of images of familiar objects based on their authenticity: an fMRI study.","authors":"Grace A Gabriel, Cristina Simões-Franklin, Georgia O'Callaghan, John Stapleton, Fiona N Newell","doi":"10.1007/s00221-024-06989-3","DOIUrl":"10.1007/s00221-024-06989-3","url":null,"abstract":"Under most circumstances, we can rely visual information to quickly and accurately discriminate \"real\" objects (e.g., fresh fruit) from \"fake\" objects (e.g., plastic fruit). It is unclear, however, whether this distinction is made early along the ventral visual stream when basic object features such as colour (e.g., primary visual cortex; V1) and texture (e.g., collateral sulcus; COS) are being processed, or whether information regarding object authenticity is extracted in later visual or memory regions (e.g., perirhinal cortex, lateral occipital cortex). To examine this question, participants were placed in an fMRI scanner, and presented with 300 objects photographed in colour or greyscale. Half of the objects were fake, and the other half were real. The participant's task was to categorise each image as presenting either a real or fake object. Broadly, our analyses revealed significant activation in CoS when participants categorised real objects, particularly when they were presented in colour. We also observed activation in V1 for coloured objects, particularly real ones. These results suggest that our seemingly intuitive ability to rapidly discriminate real from fake objects occurs at the early stages of visual processing, such as when the brain is extracting surface-feature information like texture (CoS) or colour (V1). Future studies could consider the time course of these neural events and probe the importance of cross-modal (e.g., audition and haptic) information underpinning feature extraction for distinguishing real from fake objects.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"87"},"PeriodicalIF":1.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceptual decoupling in the sustained attention to response task is likely: comment on Bedi, Russell, & Helton (2024).

IF 1.7 4区医学

Experimental Brain Research Pub Date : 2025-03-07 DOI: 10.1007/s00221-025-07032-9

Shivang Shelat, Barry Giesbrecht

{"title":"Perceptual decoupling in the sustained attention to response task is likely: comment on Bedi, Russell, & Helton (2024).","authors":"Shivang Shelat, Barry Giesbrecht","doi":"10.1007/s00221-025-07032-9","DOIUrl":"https://doi.org/10.1007/s00221-025-07032-9","url":null,"abstract":"Recent work by Bedi et al. (Experimental Brain Research 242(8):2033-2040, 2024) posits that perceptual decoupling in the sustained attention to response task (SART) is unlikely. In this commentary, we challenge their broad titular claim by revisiting two important studies: Smallwood et al. (Journal of Cognitive Neuroscience 20(3):45, 2008) and deBettencourt et al. (Nature Human Behaviour 3(8):808-816, 2019). These studies demonstrate that lapses in attention during the SART are associated with degraded neural responses and impaired memory encoding. Diminished P300 amplitudes during commission errors and periods of mind-wandering suggest that external perceptual processing is compromised when attention shifts inward. Moreover, recent methodological innovations that integrate real-time monitoring of attentional state have provided evidence of perceptual decoupling in the SART using an interleaved working memory task. Our review is meant to reaffirm the task's value in studying sustained attention, mind-wandering, and perceptual decoupling. We argue that existing evidence supports a conjecture that perceptual decoupling in the SART is likely, and that valuable new methods allow us to pivot away from commission errors as a behavioral proxy for lapsing attention.","PeriodicalId":12268,"journal":{"name":"Experimental Brain Research","volume":"243 4","pages":"86"},"PeriodicalIF":1.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0