F1000Research最新文献

{"title":"A structured dataset of the federalist society's public engagements.","authors":"Chad M Topaz","doi":"10.12688/f1000research.161735.2","DOIUrl":"10.12688/f1000research.161735.2","url":null,"abstract":"<p><strong>Background: </strong>The Federalist Society, a leading conservative legal organization, has played a significant role in shaping the American judiciary for decades. Despite its influence, comprehensive empirical data on the organization remains scarce. We address this gap by systematically documenting 20,205 public events hosted by the Society from 1984 to 2024, with substantive coverage from 2007 onward.</p><p><strong>Methods: </strong>Following ethical best practices in data collection and ownership, we gathered event metadata-including titles, dates, locations, sponsors, topics, and speakers-via web scraping from the Federalist Society's archives. The dataset is structured to facilitate analysis of event trends, co-speaking networks, and thematic shifts over time. To ensure data integrity, we performed validation, deduplication, and cleaning, resulting in a well-structured, high-quality dataset.</p><p><strong>Conclusions: </strong>This dataset provides an empirical foundation for examining the Federalist Society's role in legal discourse. It is a resource for scholars in law, political science, sociology, gender studies, network science, and computational social science, enabling investigations into key themes of discussion, event participation patterns, demographic diversity, professional backgrounds, and more. Researchers can use it to study institutional influence, legal networks, and the evolution of conservative legal thought.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"213"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12203041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144527104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol for a co-design study for the development of a chronotherapeutic mobile health behaviour change intervention targeting light exposure among older adults.","authors":"Zahrah Alwi Alkaff, Resshaya Roobini Murukesu, Denz Del Villar, Julia Woerle, Manuel Spitschan","doi":"10.12688/f1000research.157814.2","DOIUrl":"https://doi.org/10.12688/f1000research.157814.2","url":null,"abstract":"<p><p>Through its wide-ranging effects on human physiology and behaviour, daily light exposure is an important environmental modulator of healthy ageing. Integrating mobile health (mHealth) technology with behaviour change strategies offers a promising approach to optimise light exposure and positively impact sleep, rest-wake cycles, cognitive function, and mood at scale. This study aims to develop the LightSPAN mHealth behaviour change intervention to optimise light exposure across the lifespan. Employing a co-design methodology, the study comprises two distinct workstreams. The first focuses on conceptualising the theoretical framework and implementation strategies through a comprehensive review of light exposure interventions, behaviour change theories, mHealth user personas, and recommendations for designing mHealth interventions for older adults. The second workstream centres on co-designing the intervention, involving consultation with community service providers and engagement with older adults at ageing community centres (≥60 years of age). Community service providers will be consulted through a focus group discussion (target n=5). Older adult participants (n=20) will engage in telephone interviews, focus group discussions and prototyping workshops to explore older adult participants' characteristics, needs, preferences, and mHealth intervention design elements and co-design the LightSPAN mHealth behaviour change intervention. The insights generated in these co-design components will facilitate future implementation of our intervention.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1356"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144948260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of Covid-19 lungs damage based on computer tomography images analysis.","authors":"Martin Schätz, Olga Rubešová, Jan Mareš, David Girsa, Alan Spark","doi":"10.12688/f1000research.109020.3","DOIUrl":"https://doi.org/10.12688/f1000research.109020.3","url":null,"abstract":"<p><p>Modern treatment is based on reproducible quantitative analysis of available data. The Covid-19 pandemic did accelerate development and research in several multidisciplinary areas. One of them is the use of software tools for faster and reproducible patient data evaluation. A CT scan can be invaluable for a search of details, but it is not always easy to see the big picture in 3D data. Even in the visual analysis of CT slice by slice can inter and intra variability makes a big difference. We present an ImageJ tool developed together with the radiology center of Faculty hospital Královské Vinohrady for CT evaluation of patients with COVID-19. The tool was developed to help estimate the percentage of lungs affected by the infection. The patients can be divided into five groups based on percentage score and proper treatment can be applied.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"11 ","pages":"326"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144948030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycotoxin binder for immune and intestinal histopathology ameliorations against Newcastle disease in vaccinated broilers.","authors":"Erma Safitri, Hery Purnobasuki, Tita Damayanti Lestari, Suzanita Utama, Merisa Wahyu Erdhina, Maulida Ilma Sadida, Eka Pramyrtha Hestianah, Mohammad Anam Al Arif, Chairul Anwar Nidom, Sri Mulyati, Jola Rahmahani, Martia Rani Tacharina, Sri Hidanah, Siti Darodjah Rasad, Goo Jang, Mitsuhiro Takagi, Muhammad Thohawi Elziyad Purnama","doi":"10.12688/f1000research.158103.3","DOIUrl":"https://doi.org/10.12688/f1000research.158103.3","url":null,"abstract":"<p><strong>Background: </strong>In broiler farming, vaccination against Newcastle disease (ND) is essential. Nonetheless, during the post-vaccination phase, production may be negatively impacted by mycotoxin contamination in feed. This study aimed to evaluate the effect of mycotoxin binders on immune and intestinal histopathology ameliorations against ND in vaccinated broilers with aflatoxin B1 (AFB1) and ochratoxin A (OTA) toxication.</p><p><strong>Methods: </strong>A total of 20 broilers were randomly assigned into 4 groups with 5 replications i.e. (C-) broiler groups with basal feed, (C+) broiler groups with AFB1 and OTA feed contamination, (T1) and (T2) broiler groups with exposed AFB1, OTA, and toxin binders as feed additives with dose 1.1 g/kg and 1.6 g/kg feed, respectively. ND vaccination was carried out on day 7 and 21. Antibody titers were evaluated from serum samples of broiler on days 14, 28, and 35 for further hemagglutination inhibition (HI) test. Histopathology of the cecum and colon organs was evaluated using HE staining on day 36. HI test and histological scoring were analyzed using the One-Way ANOVA, followed by Duncan's test with a p < 0.05 in SPSS v.26 software (IBM Corp., Armonk, NY).</p><p><strong>Results: </strong>As a result, histopathological improvement of the cecum and colon was reported based on mucosal rupture, hemorrhage and necrosis on day 35. A significant increase in antibody titer was observed on day 35 in the C- and T2 groups, which differed significantly (p < 0.05) from the C+ and T1 groups.</p><p><strong>Conclusions: </strong>This study revealed that a 1.6 g/kg toxin binder dose in feed can increase antibody titer and histopathology of cecum and colon in broiler chickens after ND vaccination fed with mycotoxin-contaminated feed.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1518"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144948231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Notions of Fuzzy Set on Pseudo Quasi Ordered Residuated Systems.","authors":"Yeshiwas Mebrat Gubena, Teferi Getachew Alemayehu","doi":"10.12688/f1000research.165259.2","DOIUrl":"10.12688/f1000research.165259.2","url":null,"abstract":"<p><p>This paper introduces the concept of fuzzy filters and 2-fuzzy filters of a quasi-ordered residuated system <math><mi>K</mi></math> . This research explores comparative, normal, implicative and associative fuzzy filters within a quasi-ordered residuated system. It establishes the sufficient conditions under which a comparative fuzzy filter in <math><mi>K</mi></math> qualifies as a normal fuzzy filter and vice-versa. Furthermore, the study demonstrates that the collection of all comparative fuzzy filters in <math><mspace></mspace> <mi>K</mi></math> constitutes a complete lattice. The notion of fuzzy filters of a pseudo quasi-ordered residuated system is introduced and the analysis extends to fantastic, comparative, associative and implicative fuzzy filters within a pseudo quasi-ordered residuated framework. Finally, it is proven that an associative fuzzy filter in <math><mi>K</mi></math> inherently satisfies the criteria for both implicative and comparative fuzzy filters.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"566"},"PeriodicalIF":0.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an Affordable Silicone Phantom of The Kidney with 3D Printed Mould for Ultrasound Guided Percutaneous Nephrolithotomy Training in Indonesia.","authors":"Rananda Anggakara Hendarmo, Ponco Birowo, Nur Rasyid, Irfan Wahyudi, Gerhard Reinaldi Situmorang, Widi Atmoko, Mahesh Ramanlal Desai, Kevin Yonathan, Jonathan Pratama Swannjo","doi":"10.12688/f1000research.156046.2","DOIUrl":"10.12688/f1000research.156046.2","url":null,"abstract":"<p><strong>Objective: </strong>To develop an affordable kidney phantom for ultrasound guided percutaneous nephrolithotomy training model.</p><p><strong>Methods: </strong>Twenty one kidney models were manufactured and implemented as ultrasound guided percutaneous nephrolithotomy (PCNL) training models for urologists without any prior experience of independently performing PCNL in Indonesia. The unit cost of an alternative model was less than 30 USD (IDR 450,000). Twenty one junior with no prior experience of performing ultrasound guided PCNL participated in the research. The evaluation was done through anonymous responses to a questionnaire using the Likert scale.</p><p><strong>Result: </strong>The affordable PCNL model showed highly positive results among all participants (realistic anatomy 7.86/10, realistic visualization of calyx 8.19/10, realistic puncture 7.43/10, guidewire placement 8.19/10, realistic nephrostomy 7.57/10, stone visualization 7.76/10, feedback 7.52/10, post-training discussion 8.57/10). All of the participants recommended the affordable PCNL model phantom for ultrasound guided PCNL training in Indonesia.</p><p><strong>Conclusion: </strong>An affordable model utilizing 3D printed mould, silicone, and gelatine jelly is a feasible option for ultrasound guided PCNL training among urologists in developing countries. The utilization of 3D printing and silicone moulding will be beneficial in reducing the cost of surgery model while preserving the realistic tactile feedback.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"237"},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12381629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144948376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"I just very much love the journal\":  Understanding the community-led publishing landscape at the University of Cambridge.","authors":"Samuel Moore, Mandy Wigdorowitz","doi":"10.12688/f1000research.161163.2","DOIUrl":"10.12688/f1000research.161163.2","url":null,"abstract":"<p><strong>Background: </strong>A growing movement of researcher-driven publishing projects has emerged in response to several challenges and shifts within the academic publishing landscape. One publishing initiative in this area are what we term community-led publishing projects (CPPs), which are produced entirely by academics, librarians and students without any involvement of the commercial publishing industry. CPPs are part of a growing global movement but their values and practices remain underexplored. This article presents findings on the landscape of CPPs at the University of Cambridge.</p><p><strong>Methods: </strong>A landscape analysis was undertaken to identify and describe the various CPPs at Cambridge. A subset of 10 journal editors were subsequently interviewed to explore the practices, motivations and needs of these initiatives.</p><p><strong>Results: </strong>Thirty-four CPPs were identified across a range of disciplines with a variety of publishing practices, open access status and professionalisation. From the interviews, CPPs were driven by an array of motivations including volunteers who are dedicated to their disciplines, who care for publishing, have a responsibility to disseminate their own research and who acknowledge the value these projects bring. They have complicated relationships with open access, being encouraged by public access to knowledge while maintaining a desire for print and being critical of some cultures of publishing brought on by the turn to openness. Practically, they employ a \"DIY\" approach due to the availability of resources but in doing so adhere to professional standards. Their success relies on collaboration and support, leveraging networks, technical and financial backing, and ensuring sustainability through careful handover.</p><p><strong>Conclusions: </strong>This study helps us better understand the scope and practices of community-led publishing at a research-intensive university in the UK. It shows that CPPs are valuable for a variety of reasons and that universities, funders and governments should support such projects to ensure the preservation of unique scholarly content.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"266"},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12291055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144729064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Managing Odontoma and Molar-Incisor-Hypomineralization Challenges in Orthodontics.","authors":"Nora Alhazmi, Khalid Albawardi, May Aleraij, Maram A Alqahtani, Faisal O Alsharif, Sohaib Shujaat","doi":"10.12688/f1000research.154672.3","DOIUrl":"10.12688/f1000research.154672.3","url":null,"abstract":"<p><p>This clinical case report presents the comprehensive multidisciplinary management of a 15-year, 7-month-old female patient diagnosed with an odontoma-associated impaction of the mandibular right permanent canine and molar-incisor-hypomineralization (MIH). While previous studies have addressed these conditions individually, this case illustrates a unique combination requiring surgical, orthodontics, and restorative interventions. The patient presented with esthetic concerns and delayed eruption of the mandibular canine. Clinical examination revealed an Angle's Class I molar and Class II canine relationship, lingual crossbite of the maxillary right lateral incisor, impaction of the mandibular right permanent canine, retained primary canine, and MIH affecting both anterior teeth and first molars. The treatment plan involved surgical removal of the odontoma to facilitate orthodontic traction of the impacted canine. Subsequently, orthodontic treatment was initiated to correct occlusion and alignment. After successful space management and canine eruption, restorative procedures were carried out to improve the esthetics and function of MIH-affected teeth. This case highlights the importance of early diagnosis, interdisciplinary collaboration, and a customized treatment approach in managing complex mixed dental anomalies. The outcome demonstrated improved function, esthetics, and patient satisfaction.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"970"},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can indoor plants reduce formaldehyde levels in the anatomy dissection hall? A study to evaluate the practicality of using plants in reducing formaldehyde levels.","authors":"Adish G Joshi, Dhiren Punja, Rohini Punja","doi":"10.12688/f1000research.152489.3","DOIUrl":"10.12688/f1000research.152489.3","url":null,"abstract":"<p><strong>Background: </strong>Formaldehyde a commonly used embalming fluid for the preservation of cadavers, produces numerous short and long-term side effects on the students and staff working with it. Indoor plants have been shown to reduce atmospheric formaldehyde levels. The purpose of the study was to compare the efficacy of indoor plants in reducing formaldehyde levels in ambient air to levels deemed safe by WHO standards.</p><p><strong>Methods: </strong>The study was conducted in the storage room of the Anatomical dissection hall. 7 potted plants of one variety were kept in the storage room for 14 days and the Formaldehyde reading was measured using a VOC (Volatile Organic Compound) monitor. Then the same was done with no plant. This cycle was repeated 2 more times, with two different plant species. The three spieces of plants used for this study were as follows: <i>Dracaena trifasciata</i>, <i>Epipremnum aureum</i>, <i>Spathiphyllum.</i></p><p><strong>Results: </strong>The results were analysed and compared and it was determined that the effect of having a plant present versus having no plant present on the Formaldehyde concentration in the air was inconclusive as <i>Dracaena trifasciata</i> failed to reject the null hypothesis altogether (p-value>0.05), while <i>Epipremnum aureum</i> and <i>Spathiphyllum</i> rejected the null hypothesis (p-value<0.05), however they both had a weak positive correlation with formaldehyde concentration.</p><p><strong>Conclusion: </strong>The efficacy of indoor plants in reducing formaldehyde levels in ambient air needs to be further explored and validated since all the prior studies conducted were in controlled environment and should be done in a real time scenario for its practical and beneficial uses.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1249"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11803571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review Protocol on Antibiotic Use for infection related Orofacial Pain: Policy and Practice Implications.","authors":"Nishant Mehta, Richa Shrivastava, Neha Patyal, Arpit Gupta","doi":"10.12688/f1000research.163353.2","DOIUrl":"10.12688/f1000research.163353.2","url":null,"abstract":"<p><strong>Background: </strong>Dental pain and intraoral swelling, commonly resulting from pulpal and periapical infections, are leading causes of emergency visits. Overuse of antibiotics in such cases contributes to antimicrobial resistance. The appropriateness of antibiotic use must be evaluated to ensure rational prescribing and minimize unnecessary prescriptions.</p><p><strong>Objectives: </strong>This review aims to evaluate the effectiveness and associated signs and symptoms of empiric antibiotic treatment for ≤5 days compared to >5 days in patients presenting with dental pain.</p><p><strong>Methods: </strong>This protocol has been conducted following PRISMA-P guidelines. A comprehensive search of four electronic databases, such as PubMed, Scopus, Cochrane and Embase was performed to find pertinent studies. This study will follow PICOS framework, including individuals receiving antibiotic treatment for oro-facial pain. Randomized controlled trials evaluating the use of empirical antibiotics for <5 days, compared to >5 days for dental pain management. Outcomes assessed will be pain reduction, quality of life improvement, adverse events related to antibiotic, clinical resolution, microbiological and radiological findings, biomarkers, antimicrobial resistance, cost implications. Independent reviewers will screen the studies, assess the risk of bias by using RoB-2 and certainty of evidence by using GRADE. Where feasible, a meta-analysis will be conducted to synthesize findings and provide a quantitative summary of the results.</p><p><strong>Results: </strong>The study commenced in February 2025 and is anticipated to be completed by May 2025.</p><p><strong>Conclusions: </strong>This review will evaluate the effectiveness of antibiotic prescriptions for dental pain, minimizing adverse effects and identifying guideline adherence gaps. Findings will support antibiotic stewardship and inform policies to promote rational use, aiming to curb antimicrobial resistance while ensuring effective, evidence-based pain management in dental practice.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"415"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}