F1000Research最新文献

{"title":"Isolation of <i>Hymenolepis diminuta</i> cysticercoids for therapeutic use: The need for fully disclosed methodology.","authors":"Aarushi Venkatakrishnan, Chelsea Swanson, Antara Palkar, David Takamiya, Joshua T Sarafian, Jennifer Mauney, Margaret W Gatongi, Jasmine Cendejas Hernandez, Victoria Lawton, Zoie E Holzknecht, John P Jones Iii, Zacharoula Konsoula, Kateřina Jirků, Garin Aglietti, Detlev Goj, William Parker","doi":"10.12688/f1000research.186809.2","DOIUrl":"10.12688/f1000research.186809.2","url":null,"abstract":"<p><strong>Background: </strong>Helminth therapy holds considerable theoretical promise for clinical and public health applications. Unfortunately, clinical trials have often used helminths produced using methods that are both highly variable and insufficiently described in the literature, which may hinder reproducibility and troubleshooting. This study aimed to devise a method for purification of helminths that avoids mechanical filtration, which may damage some organisms. In particular, the goal was to devise a method to separate large quantities of cysticercoids of the cestode species <i>Hymenolepis diminuta</i> (HDCs), a process that has not been described previously but that would be necessary before HDCs can be used clinically.</p><p><strong>Methods: </strong>The physical size and behavior of HDCs in solution were assessed and used to create a patented washing device.</p><p><strong>Results: </strong>The cross-sectional area of HDCs varied over a 10-fold range, from approximately 0.06 to 0.6 mm ², dependent in large part upon the host. That cross-sectional area correlated in a linear fashion with the steady-state speed of HDCs while falling through solution, which varied over a 5-fold range, from approximately 0.4 mm/s to 2.0 mm/s in the solution tested. These parameters were used to develop a washing device that utilized a variable flow speed dictated by changing column diameter and an upward flowing column of liquid that effectively and simultaneously suspended HDCs of various sizes in a wash solution.</p><p><strong>Conclusions: </strong>This study describes a detailed method of purification of HDCs, organisms that could potentially be used for helminth therapy. It is hoped that government agencies or non-profit organizations can use such technology to conduct rigorous clinical trials, potentially leading to the production of reasonably priced therapeutics.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"1334"},"PeriodicalIF":0.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a Mobile Application with an AI-Powered Chatbot to Enhance Nursing Students' Awareness of Substance Abuse Prevention: An Interventional Study.","authors":"Hasan Abualruz, Eman A Shokr, Salahdein Aburuz","doi":"10.12688/f1000research.183558.2","DOIUrl":"10.12688/f1000research.183558.2","url":null,"abstract":"<p><strong>Background: </strong>Substance abuse among university students has emerged as a significant problem from a public health perspective, with specific patterns observed among the population in Jordan. Chatbots developed using artificial intelligence are effective instruments in health education delivery. This research sought to investigate the efficacy of a mobile app that incorporates AI chatbots in enhancing nursing students' knowledge about substance abuse prevention.</p><p><strong>Methods: </strong>This study employed a quasi-experimental nonequivalent control group pretest-posttest design, involving of an intervention group and a control group. The study was conducted in the largest Faculty of Nursing in Jordan with more than 2500 students' capacity, from October 2025 to February 2026. A total of 170 nursing students participated in the study; 85 students were allocated to the control group, and 85 students were assigned to the intervention group. The main study variables included Knowledge, Attitude, and Practice (KAP) domain scores, as well as Substance Use Risk Profile Scale (SURPS) scores.</p><p><strong>Results: </strong>The study results revealed that groups did not differ significantly from each other in terms of demographic variables. In the control group, there were no statistically significant changes found on all study variables, before and after the intervention. Conversely, in the experimental group, there were statistically significant changes found on the students' knowledge, attitude, and practice concerning the prevention of substance abuse (p < .001) and lower scores for all SURPS subscales p < .001. Sub-group analyses also found no statistically significant differences between the sub-groups in their responses to the intervention program (all p > .05). Multiple regression analysis also found that KAP predicted post-test SURP scores (p < .001).</p><p><strong>Conclusions: </strong>The AI-based chatbot intervention resulted in significant positive changes in substance abuse knowledge, attitudes, and preventive behaviors, as well as in acceptance of personality risks.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"1015"},"PeriodicalIF":0.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13615354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TB Stigma and Stigmatization Experienced by People with Tuberculosis: A Qualitative Study in Jakarta, Indonesia.","authors":"Aan Sutandi, Henny Suzana Mediani, Apriana Rahmawati, Sari Narulita, Maryuni Maryuni, Fatma Refaat Ahmed, Nabeel Al-Yateem, Muhammad Arsyad Subu, Richard Mottershead","doi":"10.12688/f1000research.177509.2","DOIUrl":"10.12688/f1000research.177509.2","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) remains a major global public health challenge, with Indonesia accounting for a substantial proportion of global incident disease. Although previous Indonesian studies have demonstrated the prevalence and consequences of TB-related stigma, less is known about how people receiving TB treatment experience the interconnected processes of internalised, family and public/social stigma, and how they understand the factors driving stigmatization in everyday life.</p><p><strong>Aim: </strong>This study explored stigma and stigmatization experienced by people with TB receiving treatment in two urban healthcare settings in Jakarta, Indonesia.</p><p><strong>Methods: </strong>This study used a qualitative descriptive design. Purposive sampling was used to recruit 30 adults receiving TB treatment from a hospital and a public health centre in Jakarta, Indonesia. Data were generated through individual semi-structured interviews conducted in Bahasa Indonesia and analysed using inductive qualitative content analysis.</p><p><strong>Results: </strong>Four interrelated themes were identified: (1) internalised stigma or self-stigma; (2) family stigma; (3) public/social stigma; and (4) reasons for TB stigmatization. Participants described shame and loss of social status, reduced family support, social labelling, isolation and discrimination, including consequences for employment. Stigmatization was attributed particularly to limited knowledge and misconceptions about TB, fear of infection and transmission, and association with HIV/AIDS.</p><p><strong>Conclusion: </strong>TB stigma in these Jakarta settings operated across individual, family and community levels and could remain socially consequential during treatment and anticipated recovery. Stigma-reduction strategies should therefore extend beyond education alone and combine accurate communication about transmission and curability with psychosocial and peer support, family and community engagement, and measures to address social and employment discrimination.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"1130"},"PeriodicalIF":0.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13615351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital transformation as a driver of operational sustainability in manufacturing: a systematic review (2015-2025).","authors":"Luis Edgardo Cruz Salinas, Jessica Macalopú Rimachi, Carlos José Sandoval Reyes","doi":"10.12688/f1000research.178740.2","DOIUrl":"10.12688/f1000research.178740.2","url":null,"abstract":"<p><strong>Objective: </strong>This research examines how the adoption of digital technologies-the Internet of Things (IoT), artificial intelligence, digital twins, and big data analytics-affects operational sustainability in the manufacturing sector.</p><p><strong>Design/methodology: </strong>A systematic review was conducted in accordance with the PRISMA 2020 guidelines, consulting Scopus, ScienceDirect and Taylor & Francis for the period 2015-2025. Of 1,247 initial records, 50 studies passed the eligibility and methodological quality filters.</p><p><strong>Findings: </strong>The evidence indicates that the joint implementation of several digital technologies produces reductions of between 20% and 35% in energy consumption and between 25% and 40% in material waste, according to the ranges reported in the primary studies. Digital twins had the greatest effects on process optimisation, followed by industrial IoT and artificial intelligence systems. Organisations that combined three or more complementary technologies achieved improvements 40%-60% greater than isolated implementations.</p><p><strong>Originality: </strong>The work offers a structured synthesis of the specific mechanisms that connect digitalisation with concrete sustainability indicators and identifies knowledge gaps that guide future lines of research.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"544"},"PeriodicalIF":0.0,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13146463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147835649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Prolonged Sitting Time and Sitting Posture on Low Back Pain: A Cross-Sectional Study among Medical Students at Universitas Sumatera Utara.","authors":"Jocelyn Koswara, Yetty Machrina, Mahrani Lubis, Rina Amelia","doi":"10.12688/f1000research.146596.2","DOIUrl":"https://doi.org/10.12688/f1000research.146596.2","url":null,"abstract":"<p><strong>Background: </strong>Low Back Pain (LBP) is the most common musculoskeletal disorder in the world. Medical students, particularly those who use computers for study purposes, are more vulnerable to LBP due to prolonged sitting times and improper sitting posture during lectures. However, prior research showed that the prevalence of LBP among medical students appeared lower when they were enrolled during online pandemic learning. Hence, this research is performed to determine the correlation between the duration of sitting and sitting posture on the incidence of LBP among medical students in Universitas Sumatera Utara, Indonesia.</p><p><strong>Methods: </strong>A cross-sectional study with an analytical descriptive design was conducted in September 2023 among randomly selected 147 medical students at Universitas Sumatera Utara, Indonesia. The inclusion criteria of the research sample are students with BMI< 23 kg/m2 while the exclusion criteria are students who have abnormalities and a history of trauma or spinal fractures. Data was obtained from filling out questionnaires of The Pain and Distress Scale (PAD) and Body Awareness of Postural Habit in Young People (BAPHY). A Chi-square test and logistic regression were used to analyze data with a p-value < 0.05 was regarded as statistically significant.</p><p><strong>Results: </strong>The study's findings revealed that 40.1% of students reported having LBP problems, 72.1% reported sitting for more than seven hours each day, and 33.3% reported having a bad sitting posture. Chi-square analysis revealed a significant correlation between sitting duration and posture on complaints of lower back pain (RR = 1.69, p = 0.041 and RR = 1.69, p = 0.009). At a risk of 2,438 times, sitting posture is the main factor contributing to LBP among medical students at Universitas Sumatera Utara, Indonesia.</p><p><strong>Conclusions: </strong>This research showed a significant correlation between duration and sitting posture on the incidence of low back pain.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"13 ","pages":"1379"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endocrine dysfunctions in patients with beta thalassemia major: a single-center retrospective study from Basrah.","authors":"Haider Alidrisi, Hussein Nwayyir, Mahmood Altemimi, Nassar Alibrahim, Ola Hamid, Israa Abdulbari, Nargis Noman, Abbas Mansour","doi":"10.12688/f1000research.182800.2","DOIUrl":"10.12688/f1000research.182800.2","url":null,"abstract":"<p><strong>Background: </strong>The management of patients with beta thalassemia major (BTH) involves regular blood transfusions which are associated with iron overload. This may result in various endocrine dysfunctions (EDs). This study aimed to assess the obesrved frequency of different EDs in patients with transfusion-dependent BTH.</p><p><strong>Method: </strong>A retrospective study that included 496 patients with BTH who were referred from the Basra Center for hereditary blood diseases to Faiha Specialized Diabetes, Endocrine and Metabolsim Center for endocrine-related complaints and underwent detailed endocrine assessments from Jan 2010 to Dec 2023.</p><p><strong>Results: </strong>The mean presentation age for endocrine evaluation was 13.6 ± 6.5 years with no difference between male and female. The commonest clinical presentations of BTH patients in our center were short stature 65.5%, amenorrhea 16.4, hyperglycemia 13.7%, delayed puberty 13.3, and hypocalcemia 5.2%. The proportion patients with ED was 16.8%. The most frequent EDs were growth hormone deficiency (GHD) 6.0%, diabetes mellitus (DM) 4.9%, hypogonadism 4.5%, hypothyroidism 3.2%. Within those patients, 78.7% had single ED, 16.5% had two EDs and 4.8% had three or more EDs.</p><p><strong>Conclusion: </strong>EDs were observed among patients with BTH. The commonest EDs were GHD, DM, and hypogonadism. We recommend regular and timely surveillance using both clinical and hormonal assessment in patients with BTH.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"978"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149126722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and Suicidal Ideation Among Men who have sex with men and Transgender Women in Chiang Mai, Thailand.","authors":"Kyaw Sein Lynn, Linda Aurpibul, Nuntisa Chotirosniramit, Natthapol Kosashunhanan, Kriengkrai Srithanaviboonchai, Awirut Oon-Arom","doi":"10.12688/f1000research.181753.4","DOIUrl":"10.12688/f1000research.181753.4","url":null,"abstract":"<p><strong>Background: </strong>Depression and suicidal ideation are common among men who have sex with men (MSM) and transgender women (TGW). Pre-exposure prophylaxis (PrEP) has become an important component of HIV prevention, but its relationship with mental health remains incompletely understood. This study compared depression and suicidal ideation/risk between PrEP users and non-users among MSM and TGW attending HIV prevention services, and identified factors associated with depression.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 150 MSM and TGW (75 PrEP users and 75 non-users) recruited from two HIV prevention clinics in Chiang Mai, Thailand Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9), and suicidal ideation/risk was assessed using the Columbia-Suicide Severity Rating Scale (C-SSRS). Group differences were compared using χ ² tests, Fisher's exact test, or independent-samples <i>t</i>-tests as appropriate. Multivariable linear regression was performed to identify factors associated with depression.</p><p><strong>Results: </strong>PrEP users had significantly lower mean depression scores than non-users (3.80±3.46 vs. 5.96±3.76; mean difference 2.16, 95% CI: 0.99-3.33; <i>p</i> <0.001). Suicidal ideation/risk was reported by 5 (6.7%) PrEP users and three (4.0%) non-users, with no significant difference between groups (Fisher's exact test, <i>p</i> = 0.719). In the adjusted linear regression model, PrEP use was independently associated with lower depression scores (B = -1.77, 95% CI: -3.07 to -0.47; <i>p</i> = 0.008), whereas experience of discrimination was independently associated with higher depression scores (B = -1.32, 95% CI: -2.59 to -0.06; <i>p</i> = 0.040).</p><p><strong>Conclusions: </strong>Among MSM and TGW attending HIV prevention services in Chiang Mai, PrEP use was independently associated with lower depression scores, whereas suicidal ideation/risk did not differ significantly between PrEP users and non-users. Experience of discrimination was associated with higher depression scores. Although causal inferences cannot be made, the findings highlight the importance of considering mental health alongside HIV prevention services for key populations.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"772"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex Differences in the Prevalence and Correlates of Sleep Disturbance Among Indonesian Stroke Survivors: A Population-Based Study of 7,147 Individuals.","authors":"Sri Susanty, Renny Wulan Apriliyasari, Hsiao-Yean Chiu, Rusdi Bin Abd Rashid, Era Catur Prasetya, Kanjanee Phanphairoj, Mokh Sujarwadi, Faizul Hasan","doi":"10.12688/f1000research.182846.4","DOIUrl":"10.12688/f1000research.182846.4","url":null,"abstract":"<p><strong>Objectives: </strong>Sleep disturbance is a prevalent issue among those who have experienced a stroke. The impact of gender on the prevalence of sleep disturbance within Asian stroke populations remains ambiguous. This research seeks to examine the prevalence of sleep disturbance among stroke survivors in Indonesia.</p><p><strong>Methods: </strong>This quantitative prevalence analysis was based on the 2018 Indonesian Basic Health Research. A total of 7,147 stroke survivors who answered the sleep disturbance questions were included. The estimated prevalence and regression models were examined utilizing SPSS software.</p><p><strong>Results: </strong>The total prevalence of sleep disturbance among stroke survivors in Indonesia was 28.4% (95% CI: 27.4%-29.4%). Females exhibited a greater frequency of sleep disturbance than males (34.4% versus 26.1%, respectively). When categorized by age group, both females and males exhibited a trend of rising sleep disturbance prevalence with time. Moreover, daily smoking, low educational attainment, rural residency, and insufficient physical activity were correlated with sleep disturbance symptoms in the male cohort. In females, the presence of comorbidities such as cardiovascular disease and asthma was associated with sleep disturbance.</p><p><strong>Conclusions: </strong>This study's findings revealed a significant prevalence of sleep disturbance among stroke survivors in Indonesia. Our findings indicate a gender influence on sleep disturbance prevalence, with females exhibiting a higher prevalence than males. These findings underscore the significance of sleep assessment and treatment in clinical or community environments.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"982"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bazilevic-type function associated with the class of univalent functions with study Coefficient Bounds and Fekete-Szego inequalities.","authors":"Mays S Abdul Ameer, Abdul Rahman S Juma, Hassan Hussien Ebrahim","doi":"10.12688/f1000research.172490.2","DOIUrl":"https://doi.org/10.12688/f1000research.172490.2","url":null,"abstract":"<p><strong>Background: </strong>The Fekete-Szegö inequality and coefficient bounds play a fundamental role in the study of Bazilevič-type functions, a subclass of univalent functions with significant applications in complex analysis and related mathematical fields. These functions have been extensively studied for their geometric properties and coefficient behavior, yet there remains a need to explore subclasses defined via differential operators and subordination techniques to obtain sharper and more general bounds. Understanding the coefficient structure of these functions provides insight into their analytic behavior and extends classical results in the theory of univalent functions.</p><p><strong>Methods: </strong>This study focuses on a specific subclass of Bazilevič-type functions and investigates its properties using differential subordination and differential operators. These mathematical tools are employed to derive explicit coefficient estimates and establish the Fekete-Szegö inequalities. The analysis involves careful application of operator techniques to obtain bounds that reflect the influence of the subclass parameters on the analytic functions under consideration.</p><p><strong>Results: </strong>The derived inequalities demonstrate the effectiveness of differential operators in obtaining precise coefficient constraints. The results highlight how variations in the defining parameters of the subclass influence the function behavior, providing clear and explicit bounds for the coefficients. These findings extend existing results in the literature and offer new insights into the structure of Bazilevič-type functions.</p><p><strong>Conclusions: </strong>Overall, this study provides a systematic approach to understanding the coefficient structure of Bazilevič-type functions. The findings establish a foundation for further theoretical research on univalent functions and offer tools that can be applied in both theoretical investigations and practical problems in complex analysis. The results contribute to the broader understanding of analytic functions and their applications in mathematical modeling.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Drives Indonesian People to Purchase Modest Fashion? The Moderating Role of Religiosity.","authors":"Muhammad Anwar Fathoni, Dienni Ruhjatini Sholihah, Ajeng Septiana Wulansari","doi":"10.12688/f1000research.173033.4","DOIUrl":"10.12688/f1000research.173033.4","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to examine how religiosity moderates the influence of attitude and electronic word of mouth (E-WOM) on purchase decisions in Indonesia's modest fashion market. It seeks to provide empirical evidence on how cognitive, social, and spiritual factors interact in shaping Muslim consumers' purchasing behavior.</p><p><strong>Design/methodology/approach: </strong>A quantitative research approach was employed using Structural Equation Modeling (SEM) with data collected from 320 Muslim consumers in Jakarta and surrounding areas. The constructs (attitude, E-WOM, religiosity, and purchase decision) were measured using validated multi-item scales adapted from previous studies.</p><p><strong>Findings: </strong>The results indicate that both attitude and E-WOM have significant positive effects on purchase decisions, with E-WOM being the most dominant factor. Religiosity exerts a direct positive influence and strengthens the relationship between attitude and purchase decision, but does not moderate the effect of E-WOM. These findings highlight that while religiosity enhances value-driven behavior, digital influence transcends religious intensity.</p><p><strong>Practical implications: </strong>The study suggests that modest fashion marketers should integrate syariah-compliant values with credible digital engagement strategies to foster consumer trust and loyalty. Balancing faith-based authenticity with modern digital communication can enhance brand relevance in the halal fashion market.</p><p><strong>Originality/value: </strong>This study extends the Theory of Planned Behavior (TPB) by incorporating religiosity as a moderating factor within the context of Islamic consumer behavior. It contributes to the growing body of Islamic marketing literature by revealing how faith and digital interaction jointly shape purchase decisions in the modest fashion industry.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"127"},"PeriodicalIF":0.0,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}