Mohammad Shakil Ahmad,Yousef Abud Alanazi,Yousef Alrohaimi,Riyaz Ahamed Shaik,Sami Alrashidi,Yazeed A Al-Ghasham,Yasir S Alkhalifah,Ritu Kumar Ahmad
{"title":"Infant nutrition at risk: a global systematic review of ochratoxin A in human breast milk-human health risk assessment.","authors":"Mohammad Shakil Ahmad,Yousef Abud Alanazi,Yousef Alrohaimi,Riyaz Ahamed Shaik,Sami Alrashidi,Yazeed A Al-Ghasham,Yasir S Alkhalifah,Ritu Kumar Ahmad","doi":"10.1080/19440049.2024.2401976","DOIUrl":"https://doi.org/10.1080/19440049.2024.2401976","url":null,"abstract":"Human breast milk is the optimal source of nutrition for newborns, but the potential transfer of contaminants like mycotoxins, particularly ochratoxin A (OTA), from maternal blood to milk remains a concern. This systematic review aims to provide a comprehensive analysis of global OTA levels in human breast milk and assess the associated health risks. We conducted a thorough search of scientific databases, including Web of Science, ScienceDirect, Scopus, Google Scholar and PubMed, using keywords related to OTA in human breast milk. A total of 39 studies met the inclusion criteria for this review. OTA levels compared to limits, estimated infant intake at various ages and health risks assessed using Margin of Exposures (MOEs) and Hazard quotient (HQ). Our findings reveal the widespread presence of OTA in breast milk across different regions, with notably higher levels detected in Africa compared to Asia, South America and Europe. The higher concentrations observed in warmer, humid climates suggest that environmental factors significantly influence OTA contamination. Mature breast milk samples generally exhibited greater OTA exposure. The neoplastic and non-neoplastic effects demonstrate generally low risks globally. The regional differences in OTA levels and associated health risk assessments underscore the need for continued research into the health impacts of OTA exposure in infants. This includes further investigation into multiple sources of exposure, such as infant formula, within the broader context of the exposome framework.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"210 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142269276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination and evaluation of canthaxanthin and β-apo-8'-carotenoid ethyl ester in chicken eggs and meat in Tianjin.","authors":"Xinghua Li,Siyu Yang,Weiyi Jin,Yeqing Jia,Kang An,Jianping Li,Yi Zhang","doi":"10.1080/19440049.2024.2401973","DOIUrl":"https://doi.org/10.1080/19440049.2024.2401973","url":null,"abstract":"Canthaxanthin and β-apo-8'-carotenoid ethyl ester are widely used as feed additives in poultry feed for enhancing the color of poultry products. The excessive intake of the two colorants can cause health damage. According to the European Food Safety Authority (EFSA), the acceptable daily intake (ADI) of canthaxanthin and β-apo-8'-carotenoid ethyl ester are 0.03 mg/kg·bw and 0.015 mg/kg·bw, respectively. Ultra-high-performance liquid chromatography-diode array detector (UPLC-DAD) was used to determine two colorants in chicken eggs and meat. A PRiME HLB solid-phase extraction cartridge was used to extract and clean-up the sample. BEH C18 column was used as the separation column, with water containing 0.1% formic acid and acetonitrile as the mobile phase. The limit of detection (LOD) was 0.05 mg/kg, and the limit of quantification (LOQ) was 0.1 mg/kg. The recoveries were between 90% and 104%. The daily intake of two colorants in chicken eggs and meat was evaluated based on the detection data, food consumption data and weight data of the population. The mean estimated daily intake (EDI) values of canthaxanthin through chicken eggs and meat were 1.09 µg/(kg·bw·d) and 0.013 µg/(kg·bw·d), respectively. The mean EDI value of β-apo-8'-carotenoid ethyl ester through eggs was 0.44 µg/(kg·bw·d). The results showed that eggs were the main contributor to the daily intake of two colorants. The mean hazard quotients (HQ) values of two colorants through chicken eggs and meat was within a safe range.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"27 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142263708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A worldwide systematic review of ochratoxin A in various coffee products - human exposure and health risk assessment.","authors":"Tooraj Massahi,Amir Kiani,Masoud Moradi,Hamed Soleimani,Abdullah Khalid Omer,Mohammad Hossein Habibollahi,Borhan Mansouri,Kiomars Sharafi","doi":"10.1080/19440049.2024.2400697","DOIUrl":"https://doi.org/10.1080/19440049.2024.2400697","url":null,"abstract":"Coffee is one of the most commonly consumed beverages worldwide, so assessing its quality for potential health risks is essential. Therefore, this review aimed to determine the levels of ochratoxin A (OTA) in coffee worldwide and then estimate its human intake and health risks. The systematic search took place from June 1997 to April 2024 and 40 of 254 articles were selected based on the selection criteria. The results showed significant differences in average levels of OTA between countries, continents and coffee types (p < 0.001). Of 3256 samples, OTA was detected in 1778, accounting for 54.6% of the total, with the percentage of positive results varying between 7.5% and 100%. Only two studies reported OTA average levels in roasted coffee exceeding the maximum limit (ML) set by the European Commission (ML-EC = 5 μg/kg). The average OTA in soluble coffee was lower than ML-EC (10 μg/kg) in all studies, and in instant coffee, the level of OTA was higher than ML-EC (10 μg/kg) only in one study. The estimated daily intake (EDI) of OTA in all coffee types was lower than the provisional tolerable daily intake (PTDI) values set by joint FAO/WHO Expert Committee on Food Additives (JECFA) (14 ng/kg bw/day) and proposed by the European Food Safety Authority (EFSA) (17 ng/kg bw/day). Non-carcinogenic risk assessment through coffee consumption indicated that the hazard quotient (HQ) was below the acceptable level, HQ = 1. The Margin of Exposure (MoE) for neoplastic effects was acceptable and unacceptable for non-neoplastic effects (NNE) in 4.5% (one of 22 cases) of the roasted and soluble coffees, but acceptable for all instant coffees. In conclusion, the study shows that the OTA content of coffee is not toxic to consumers worldwide. However, preventative measures should be taken, including inhibiting fungal growth and reducing OTA-producing fungal growth.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"30 1","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of azodicarbonamide in flour samples using high-performance liquid chromatography-tandem mass spectrometry with xanthydrol pre-column derivatisation.","authors":"Li Hang,Huamei Yang,Wenliang Ji","doi":"10.1080/19440049.2024.2400238","DOIUrl":"https://doi.org/10.1080/19440049.2024.2400238","url":null,"abstract":"Azodicarbonamide (ADA) is approved as a food additive in flour products due to its oxidising and bleaching properties. However, it is prohibited in Australia and Europe on account of its toxicity and the risk of causing asthma in humans. A method was developed to determine ADA in actual flour samples. This work presents an optimised methodology based on derivatisation and clean-up procedures followed by ultra-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry (UPLC-ESI-MS/MS). The analytical method was successfully validated. An excellent result was obtained for the linearity of matrix-matched calibration curves (R2 > 0.99) in the concentration range of 0.10-80 mg/kg. The recovery rate varied from 81.7% to 102.3%. The relative standard deviations (RSDs) of repeatability (n = 6) were 1.3-4.1%, and inter-day RSDs (n = 6) were 2.2-4.8%. The limit of detection and the limit of quantification were 0.014 and 0.042 mg/kg, which were significantly lower than the requirement of 45 mg/kg stipulated in the Chinese National Food Safety Standard (GB 2760-2014). The detection rate of ADA in 26 flour samples was 23.1%, with the concentration ranging from 0.023 to 23.2 mg/kg.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"43 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmadullah Zahir, Ifikhar Ali Khan, Maazullah Nasim, Mohammad Naeem Azizi, Fidelis Azi
{"title":"Food process contaminants: formation, occurrence, risk assessment and mitigation strategies – a review","authors":"Ahmadullah Zahir, Ifikhar Ali Khan, Maazullah Nasim, Mohammad Naeem Azizi, Fidelis Azi","doi":"10.1080/19440049.2024.2381210","DOIUrl":"https://doi.org/10.1080/19440049.2024.2381210","url":null,"abstract":"Thermal treatment of food can lead to the formation of potentially harmful chemicals, known as process contaminants. These are adventitious contaminants that are formed in food during processing an...","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"245 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141739710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khaled El Hawari, Mohammad El Khatib, Mariam Zeineh, Daniel Beh, Farouk Jaber, Samia Mokh
{"title":"Contaminant and residue profiles in Lebanese food: a comparative analysis with global standards","authors":"Khaled El Hawari, Mohammad El Khatib, Mariam Zeineh, Daniel Beh, Farouk Jaber, Samia Mokh","doi":"10.1080/19440049.2024.2374358","DOIUrl":"https://doi.org/10.1080/19440049.2024.2374358","url":null,"abstract":"Lebanon’s agricultural sector, known for its diverse crop and livestock production, faces challenges in the international market due to the presence of chemical residues and contaminants in its foo...","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141739714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acid-based deep eutectic solvents followed by GFAAS for the speciation of As(III), As(V), total inorganic arsenic and total arsenic in rice samples","authors":"Nazir Fattahi, Hawre Lateef Ahmed, Ziba Nematifar, Negin Hashemi, Masoud Moradi, Shahin Soltani, Shahram Akbari","doi":"10.1080/19440049.2024.2344225","DOIUrl":"https://doi.org/10.1080/19440049.2024.2344225","url":null,"abstract":"In the present study, an efficacious, safe, inexpensive and eco-friendly microextraction was provided by deep eutectic solvents based on dispersive liquid–liquid microextraction (DLLME − DES) follo...","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140812038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Butovskaya, Alicia Maria Carrillo Heredero, Giulia Segato, Elena Faggionato, Marialuisa Borgia, Daniela Marchis, Simonetta Menotta, Simone Bertini
{"title":"Quantitative determination of tetracyclines in medicated feed for food-producing animals by HPLC–DAD","authors":"Elena Butovskaya, Alicia Maria Carrillo Heredero, Giulia Segato, Elena Faggionato, Marialuisa Borgia, Daniela Marchis, Simonetta Menotta, Simone Bertini","doi":"10.1080/19440049.2024.2341115","DOIUrl":"https://doi.org/10.1080/19440049.2024.2341115","url":null,"abstract":"Tetracyclines are a group of antibiotic substances largely administered through medicated feed to control diseases in food-producing animals. Fine dosing of antibiotics contained in medicated feed ...","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140812171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yaxin Li, Baoguo Chen, Shuhong Ye, Qi Wu, Lin Zhu, Yan Ding
{"title":"Discrimination of untreated and sodium sulphite treated bean sprouts by Fourier transform infrared spectroscopy and chemometrics","authors":"Yaxin Li, Baoguo Chen, Shuhong Ye, Qi Wu, Lin Zhu, Yan Ding","doi":"10.1080/19440049.2024.2341104","DOIUrl":"https://doi.org/10.1080/19440049.2024.2341104","url":null,"abstract":"Sprouts of black beans (Phaseolus vulgaris L.), soybeans (Glycine max L.) and mung beans (Vigna radiata L.) are widely consumed foods containing abundant nutrients with biological activities. They ...","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140635300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Rita Soares Mateus, Carmen Crisafulli, Silvia Cruz Barros, Angelina Pena, Ana Sanches Silva
{"title":"Development and validation of an analytical method based on QuEChERS followed by UHPLC–ToF-MS for the determination of tropane alkaloids in buckwheat (Fagopyrum esculentum L.) and buckwheat products","authors":"Ana Rita Soares Mateus, Carmen Crisafulli, Silvia Cruz Barros, Angelina Pena, Ana Sanches Silva","doi":"10.1080/19440049.2024.2339325","DOIUrl":"https://doi.org/10.1080/19440049.2024.2339325","url":null,"abstract":"A method was developed for the determination of tropane alkaloids (TAs), including atropine, scopolamine, anisodamine and homatropine in buckwheat and related products. This work presents an optimi...","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140624787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}