Food Additives & Contaminants: Part A最新文献_第10页

A PBPK model to study the transfer of α-hexabromocyclododecane (α-HBCDD) to tissues of fast- and slow-growing broilers 采用PBPK模型研究α-六溴环十二烷(α-HBCDD)在快、慢生长肉鸡组织中的转移

Food Additives & Contaminants: Part A Pub Date : 2019-11-07 DOI: 10.1080/19440049.2019.1681596

B. Méda, A. Travel, Y. Guyot, J. Henri, E. Royer, E. Baéza-Campone, C. Jondreville

{"title":"A PBPK model to study the transfer of α-hexabromocyclododecane (α-HBCDD) to tissues of fast- and slow-growing broilers","authors":"B. Méda, A. Travel, Y. Guyot, J. Henri, E. Royer, E. Baéza-Campone, C. Jondreville","doi":"10.1080/19440049.2019.1681596","DOIUrl":"https://doi.org/10.1080/19440049.2019.1681596","url":null,"abstract":"ABSTRACT A physiologically based pharmacokinetic (PBPK) model was developed to investigate the production-specific factors involved in the transfer of α-hexabromocyclododecane (α-HBCDD) to broiler meat. The model describes growth and lipid deposition in tissues of fast- (FG) and slow- (SG) growing broilers from hatching to slaughter and simulates the exposure through the ingestion of contaminated feed or expanded polystyrene insulation material. Growth parameters were obtained from the literature while parameters relative to uptake, distribution, and elimination of α-HBCDD were adjusted using results of a previous experiment involving broilers exposed through feed throughout the rearing period or allowed to depurate before slaughter. The model was used to compare the two main edible tissues, breast and leg meat, as well as skin, and to investigate the variability within strain. Between strains and within strain, α-HBCDD assimilation efficiency (AE) is higher when the animals are slaughtered young or heavy. However, increasing slaughter age will lower α-HBCDD concentration in tissues, due to dilution. Based on fresh weight, the concentration of α-HBCDD in breast muscles and skin tends to be lower in SG than in FG broilers (−30 to +10%), while it is 10% to 80% higher in leg muscles. Compared to breast muscles, consuming leg muscles would elicit an exposure 9 and 16 times higher in FG and SG broilers, respectively. The consumption of skin together with muscles would multiply the exposure by up to 36 times compared to breast muscle alone. In case of acute exposure, the α-HBCDD concentration in tissues increased sharply, all the more since the animals are lighter in weight, and then decreased rapidly. In FG broilers, dilution through growth contributed for up to 37%, 28% and 97% to the decontamination of breast muscles, leg muscles and skin, respectively, depending on the duration of depuration before slaughter.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"34 1","pages":"316 - 331"},"PeriodicalIF":0.0,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82745641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Validation of a method for the determination of triphenylmethane dyes in trout and shrimp with superior extraction efficiency 鳟鱼和虾中三苯基甲烷染料提取效率的验证

Food Additives & Contaminants: Part A Pub Date : 2019-11-07 DOI: 10.1080/19440049.2019.1671611

J. Eich, D. Bohm, Dagmar Holzkamp, J. Mankertz

{"title":"Validation of a method for the determination of triphenylmethane dyes in trout and shrimp with superior extraction efficiency","authors":"J. Eich, D. Bohm, Dagmar Holzkamp, J. Mankertz","doi":"10.1080/19440049.2019.1671611","DOIUrl":"https://doi.org/10.1080/19440049.2019.1671611","url":null,"abstract":"ABSTRACT The described methods are able to analyse the triphenylmethane dyes malachite green (MG), crystal violet (CV) and brilliant green (BG) as well as their leuco metabolites leuco malachite green (LMG), leuco crystal violet (LCV) and leuco brilliant green (LBG) on the basis of a simple and fast extraction. The validation of the methods in two studies without and with a heated ultrasonic treatment during the extraction of fortified trout and shrimp samples was successfully performed applying an in-house validation concept. The evaluation of the relevant validation parameters, e.g. the decision limit CCα, the detection capability CCβ, the repeatability, the within-laboratory reproducibility and the recovery for both extraction versions, showed results which fulfil the requirements of Commission Decision 2002/657/EC. The investigation of incurred material of trout containing the above compounds with an additional heated ultrasonic treatment during extraction leads to higher findings of MG and BG. This effect was also confirmed by other laboratories in the framework of a proficiency test. For CV and all three leuco metabolites no increase in the detected amounts could be observed after a heated ultrasonic treatment of the incurred trout material. GRAPHICAL ABSTRACT","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"14 1","pages":"84 - 93"},"PeriodicalIF":0.0,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83357142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Use of fumaric acid to control pH and inhibit malolactic fermentation in wines 富马酸在葡萄酒中控制pH和抑制苹果乳酸发酵中的应用

Food Additives & Contaminants: Part A Pub Date : 2019-11-07 DOI: 10.1080/19440049.2019.1684574

A. Morata, M. Bañuelos, C. López, Chenli Song, R. Vejarano, I. Loira, F. Palomero, J. S. Suarez Lepe

引用次数: 18

Empirical models to predict the effect of sterilisation and storage on bisphenols migration from metallic can coatings into food simulants 预测灭菌和储存对双酚类物质从金属罐涂层迁移到食品模拟物的影响的经验模型

Food Additives & Contaminants: Part A Pub Date : 2019-10-14 DOI: 10.1080/19440049.2019.1670870

Sara Noureddine El Moussawi, Mathieu Cladière, H. Chébib, R. Ouaini, V. Camel

{"title":"Empirical models to predict the effect of sterilisation and storage on bisphenols migration from metallic can coatings into food simulants","authors":"Sara Noureddine El Moussawi, Mathieu Cladière, H. Chébib, R. Ouaini, V. Camel","doi":"10.1080/19440049.2019.1670870","DOIUrl":"https://doi.org/10.1080/19440049.2019.1670870","url":null,"abstract":"ABSTRACT Based on response surface methodology, empirical models were built to predict the influence of can processing (heat treatment) and storage conditions (time and temperature) on the migration of bisphenol compounds from the inner lacquer of tinplate cans (4 brands) into several food simulants. Analysis using liquid chromatography revealed the presence of BADGE.2H2O and BPA in all samples. Models were significant in fitting the levels of these two bisphenols in food simulants depending on the input variables, with excellent adjusted coefficients of determination. Their prediction performance was validated through running new data sets. Further comparison of predicted values with bisphenols levels measured in canned vegetables revealed that the proposed models are conservative. By the desirability of the response output, the models are capable of proposing the range of can processing and storage conditions that limit migration for further compliance with the regulation. The proposed approach could be a convenient tool for the industries to control processing conditions in order to ensure the conformity of canned foods.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"163 1","pages":"1937 - 1949"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80311326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Assessment of heavy metals in calcium carbide treated mangoes by inductively coupled plasma-mass spectrometry (ICP-MS) 电感耦合等离子体质谱法(ICP-MS)测定电石处理芒果中重金属

Food Additives & Contaminants: Part A Pub Date : 2019-10-11 DOI: 10.1080/19440049.2019.1671990

S. Hassan, Wardah Mazhar, Sabiha Farooq, Arslan Ali, S. Musharraf

引用次数: 7

Kresoxim-methyl and famoxadone as activators of toxigenic potential of Aspergillus carbonarius 甲基克雷索辛和法莫沙酮对碳曲霉产毒潜能的激活作用

Food Additives & Contaminants: Part A Pub Date : 2019-10-10 DOI: 10.1080/19440049.2019.1670869

C. Costa, M. B. Cerqueira, J. Garda-Buffon

{"title":"Kresoxim-methyl and famoxadone as activators of toxigenic potential of Aspergillus carbonarius","authors":"C. Costa, M. B. Cerqueira, J. Garda-Buffon","doi":"10.1080/19440049.2019.1670869","DOIUrl":"https://doi.org/10.1080/19440049.2019.1670869","url":null,"abstract":"ABSTRACT Ochratoxin A (OTA) is a secondary metabolite produced by filamentous fungi species belonging to the genera Penicillium and Aspergillus. The contamination of grapes by ochratoxigenic species occurs worldwide in regions of tropical and temperate climates. Better control of fungal growth is achieved through good cultural practice and proper selection of fungicides. Kresoxim-methyl and famoxadone are the most common fungicides used in vineyards. This study aimed at analysing the OTA production and toxigenic potential of Aspergillus carbonarius under fungicide treatment with famoxadone and kresoxim-methyl. The growth rate of A. carbonarius was evaluated by measuring the glucosamine content and the diameter of the fungal colonies. OTA production was quantified by HPLC analysis. The treatment with fungicides, kresoxim-methyl and famoxadone, significantly reduced the fungal growth, by 76% and 60%, respectively. However, the mycotoxin production was greater in the fungicide-treated groups than the control group, showing that even though the fungicides were effective in controlling fungal growth, they were ineffective against mycotoxin production. Graphical Abstract","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"12 1","pages":"1860 - 1870"},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76690010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Standard reference material (SRM) DNA barcode library approach for authenticating Antidesma bunius (L.) Spreng. (bignay) derived herbal medicinal products 标准参比物(SRM) DNA条形码文库法鉴定黄假蝇(Antidesma buunius)Spreng。(bignay)衍生的草药产品

Food Additives & Contaminants: Part A Pub Date : 2019-10-09 DOI: 10.1080/19440049.2019.1670868

N. K. G. Alfeche, S. D. A. Binag, M. P. Medecilo, G. D. Alejandro

{"title":"Standard reference material (SRM) DNA barcode library approach for authenticating Antidesma bunius (L.) Spreng. (bignay) derived herbal medicinal products","authors":"N. K. G. Alfeche, S. D. A. Binag, M. P. Medecilo, G. D. Alejandro","doi":"10.1080/19440049.2019.1670868","DOIUrl":"https://doi.org/10.1080/19440049.2019.1670868","url":null,"abstract":"ABSTRACT In the Philippines, the herbal medicinal product (HMP) market is flourishing due to the abundance of pharmacologically important species, and the high level of ethnomedicinal knowledge still widely accepted by the public. As such, herbal products from Antidesma bunius (L.) Spreng., locally known as bignay, are popular as medicine for various ailments of the circulatory and digestive systems. Though efficacy is guaranteed, the authenticity of the marketed products is still in question as several other herbal plants can provide the said benefits. Similar morphology between wild species also hinders species identification and contributes confusion especially to the general consumer. The authenticity of the marketed HMPs was established by means of DNA barcoding techniques which offers quick and reliable species identification by means of (1) the Basic Local Alignment Search Tool (BLASTn) and (2) the establishment of the first Standard Reference Material (SRM) Herbal barcode library for Antidesma spp. A total of 56 gene accessions from matK-psbA-trnH-rbcL sequences of 9 wild Antidesma spp. comprised the SRM which was then used to confirm the identity of 11 randomly sampled bignay-derived HMPs. Following the BLASTn and the SRM (maximum likelihood tree reconstruction) criterion, the subjected sequences revealed that only three of the 11 HMPs were authentic A. bunius-derived products. The other eight HMPs contained substitutes that were either fillers or different herbal medicinal plant not indicated in the product labels. These results indicate that product safety should be reinforced with complete HMP authentication using traditional methods supported by molecular data.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"461 1","pages":"1777 - 1786"},"PeriodicalIF":0.0,"publicationDate":"2019-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77892578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Validation of an analytical method using HS-SPME-GC/MS-SIM to assess the exposure risk to carbonyl compounds and furan derivatives through beer consumption 利用HS-SPME-GC/MS-SIM分析啤酒中羰基化合物和呋喃衍生物暴露风险的方法验证

Food Additives & Contaminants: Part A Pub Date : 2019-10-09 DOI: 10.1080/19440049.2019.1672897

K. C. Hernandes, É. A. Souza-Silva, C. F. Assumpção, C. Zini, J. Welke

{"title":"Validation of an analytical method using HS-SPME-GC/MS-SIM to assess the exposure risk to carbonyl compounds and furan derivatives through beer consumption","authors":"K. C. Hernandes, É. A. Souza-Silva, C. F. Assumpção, C. Zini, J. Welke","doi":"10.1080/19440049.2019.1672897","DOIUrl":"https://doi.org/10.1080/19440049.2019.1672897","url":null,"abstract":"ABSTRACT Compounds with toxic potential may occur in beer, such as carbonyl compounds (acetaldehyde, acrolein, ethyl carbamate [EC] and formaldehyde) and furan derivatives [furfural and furfuryl alcohol (FA)]. The objective of this study was, for the first time, to validate a method based on headspace-solid phase microextraction using a PDMS-overcoated fibre and gas chromatography with mass spectrometric detection in selected ion monitoring mode (HS-SPME-GC/MS-SIM) to investigate target carbonyl compounds and furan derivatives in beers. Analytical curves showed proper linearity with r2 ranging from 0.9731 to 0.9960 for acetaldehyde and EC, respectively. The lowest LOD was found for acetaldehyde (0.03 µg L−1), while the lowest LOQ value (1.0 µg L−1) was found for acetaldehyde and EC, formaldehyde and furfural. Recovery (90% to 105%), intermediate precision and repeatability (lower than 13%), limits of detection and quantification (values below 2.5 μg L−1) showed that the method is suitable to simultaneously quantify these compounds. EC was detected in only two samples (1 lager and 1 ale). Furfural was found in 37% and 82% of ale and lager beers, respectively. Acetaldehyde, acrolein, formaldehyde and FA were detected in all samples. However, acrolein was the only compound found in the commercial samples at a concentration capable of causing health risk. Besides furfural and FA, four other furan-containing compounds (5-methyl-2-furan methanethiol, acetylfuran, 5-methylfurfural and γ-nonalactone) were also found in beers, however, at levels low enough not to impose potential health risk. Graphical Abstract","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"10 1","pages":"1808 - 1821"},"PeriodicalIF":0.0,"publicationDate":"2019-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84187117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Managing the analytical challenges related to micro- and nanoplastics in the environment and food: filling the knowledge gaps 管理与环境和食品中的微塑料和纳米塑料相关的分析挑战:填补知识空白

Food Additives & Contaminants: Part A Pub Date : 2019-10-09 DOI: 10.1080/19440049.2019.1673905

P. Alexy, E. Anklam, T. Emans, A. Furfari, F. Galgani, G. Hanke, A. Koelmans, R. Pant, H. Saveyn, Birgit Sokull Kluettgen

{"title":"Managing the analytical challenges related to micro- and nanoplastics in the environment and food: filling the knowledge gaps","authors":"P. Alexy, E. Anklam, T. Emans, A. Furfari, F. Galgani, G. Hanke, A. Koelmans, R. Pant, H. Saveyn, Birgit Sokull Kluettgen","doi":"10.1080/19440049.2019.1673905","DOIUrl":"https://doi.org/10.1080/19440049.2019.1673905","url":null,"abstract":"ABSTRACT This paper identifies knowledge gaps on the sustainability and impacts of plastics and presents some recommendations from an expert group that met at a special seminar organised by the European Commission at the end of 2018. The benefits of plastics in society are unquestionable, but there is an urgent need to better manage their value chain. The recently adopted European Strategy for Plastics stressed the need to tackle the challenges related to plastics with a focus on plastic litter including microplastics. Microplastics have been detected mainly in the marine environment, but also in freshwater, soil and air. Based on today’s knowledge they may also be present in food products. Although nanoplastics have not yet been detected, it can be assumed that they are also present in the environment. This emerging issue presents challenges to better understand future research needs and the appropriate immediate actions to be taken to support the necessary societal and policy initiatives. It has become increasingly apparent that a broad and systematic approach is required to achieve sustainable actions and solutions along the entire supply chain. It is recognised that there is a pressing need for the monitoring of the environment and food globally. However, despite the number of research projects increasing, there is still a lack of suitable and validated analytical methods for detection and quantification of micro- and nanoplastics. There is also a lack of hazard and fate data which would allow for their risk assessment. Some priorities are identified in this paper to bridge the knowledge gaps for appropriate management of these challenges. At the same time it is acknowledged that there is a great complexity in the challenges that need to be tackled before a really comprehensive environmental assessment of plastics, covering their entire life cycle, will be possible.","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"136 1","pages":"1 - 10"},"PeriodicalIF":0.0,"publicationDate":"2019-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82450305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 49

Direct infusion electrospray ionisation mass spectrometry applied in the detection of adulteration of coconut oil with palm kernel oil 直接输注电喷雾质谱法检测椰子油与棕榈仁油掺假

Food Additives & Contaminants: Part A Pub Date : 2019-10-08 DOI: 10.1080/19440049.2019.1669834

J. Pizzo, M. Galuch, L. Manin, P. Santos, Caroline Zappielo, Oscar de Oliveira Santos Júnior, J. Visentainer

{"title":"Direct infusion electrospray ionisation mass spectrometry applied in the detection of adulteration of coconut oil with palm kernel oil","authors":"J. Pizzo, M. Galuch, L. Manin, P. Santos, Caroline Zappielo, Oscar de Oliveira Santos Júnior, J. Visentainer","doi":"10.1080/19440049.2019.1669834","DOIUrl":"https://doi.org/10.1080/19440049.2019.1669834","url":null,"abstract":"ABSTRACT Coconut oil has properties that are beneficial to human health. It assists in reducing total cholesterol, triacylglycerol (TAG), phospholipids, low-density lipoprotein (LDL) cholesterol, and very low-density lipoprotein (VLDL) cholesterol in serum and tissues. So its production, and consequently consumption, have increased in recent years. However, it has been a target for intentional adulteration with lower priced oils and fats, such as soybean oil and palm kernel oil (PKO). Coconut oil (CO) and PKO have similar chemical and physical characteristics that make it difficult to verify adulteration of CO with PKO. This study demonstrates a simple, sensitive, and fast technique that uses direct infusion electrospray ionisation mass spectrometry (ESI-MS) in conjunction with principal component analysis (PCA), in order to detect CO adulterated with PKO. Among the seven commercial coconut oil samples analysed, three were adulterated with PKO. Therefore, the suggested direct infusion ESI-MS method can be used in routine analysis to guarantee the quality of coconut oil. Graphical Abstract","PeriodicalId":12121,"journal":{"name":"Food Additives & Contaminants: Part A","volume":"55 1","pages":"1597 - 1604"},"PeriodicalIF":0.0,"publicationDate":"2019-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82117580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5