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VIRTUAL CT COLONOSCOPY: METHODOLOGY FOR CONDUCTING RESEARCH AND INTERPRETATION 虚拟ct结肠镜检查:进行研究和解释的方法学
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-10-11 DOI: 10.52340/jecm.2021.552
I. Tandilava, O. Urushadze, D. Tsetskhladze, Irakli Avazashvili, G. Tsetskhladze, M. Phutkaradze, E. Diasamidze
{"title":"VIRTUAL CT COLONOSCOPY: METHODOLOGY FOR CONDUCTING RESEARCH AND INTERPRETATION","authors":"I. Tandilava, O. Urushadze, D. Tsetskhladze, Irakli Avazashvili, G. Tsetskhladze, M. Phutkaradze, E. Diasamidze","doi":"10.52340/jecm.2021.552","DOIUrl":"https://doi.org/10.52340/jecm.2021.552","url":null,"abstract":"Virtual CT colonoscopy is an accurate, highly informative, and less invasive method of examining the colon. The predominant and additional positive ability of virtual CT colonoscopy is the ability to detect non-intestinal pathologies. Based on the high sensitivity and specificity of the method to the developmental abnormalities of the colon, diverticula, polyps, cancer and other volumetric formations, we can conclude that virtual CT colonoscopy is one of the main methods of diagnosis and screening for diseases of the colon.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87514124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE SIGNIFICANCE OF THE STUDY OF THE LIVER FUNCTION TEST WITHIN POST-TRANSPLANT PATIENTS 肝移植后患者肝功能检测研究的意义
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-10-11 DOI: 10.52340/jecm.2021.556
M. Nakashidze, Z. Chikhladze, David Kobuladze, David Beridze
{"title":"THE SIGNIFICANCE OF THE STUDY OF THE LIVER FUNCTION TEST WITHIN POST-TRANSPLANT PATIENTS","authors":"M. Nakashidze, Z. Chikhladze, David Kobuladze, David Beridze","doi":"10.52340/jecm.2021.556","DOIUrl":"https://doi.org/10.52340/jecm.2021.556","url":null,"abstract":"In recent years, the survival rate of patients after liver transplantation (LT) has improved significantly. However, successful transplantation is directly related to the proper management of the patient after surgery, including considering essential aspects based on the results of laboratory tests. Therefore, it is essential to study the laboratory characteristics to investigate the functional state of the liver. In the present study, we investigated the indicators of liver function in postoperative patients: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), albumin, total bilirubin, gamma-glutamyl transferase (GGT). Venous blood samples were used for investigation. A total of 10 post-transplant patients were studied. Appropriate research methods were used. P<0.05 was considered statistically significant. Overall, our results have shown that intensive examinations of the liver panel in postoperative patients significantly contribute to the proper management of the complicated patient, which directly impacts the final results. Notably, the variability of GGT and ALP may be directly related to the transplanted chronic immune response of the liver and may be used as an early marker for the diagnosis of biliary complications.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86155555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BOTULINUM TOXIN EFFECTIVENESS IN PRIMARY HYPERHIDROSIS PATIENTS 肉毒杆菌毒素治疗原发性多汗症的疗效
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-10-11 DOI: 10.52340/jecm.2021.563
Tinatin Ghibradze, T. Kituashvili, M. Lomidze
{"title":"BOTULINUM TOXIN EFFECTIVENESS IN PRIMARY HYPERHIDROSIS PATIENTS","authors":"Tinatin Ghibradze, T. Kituashvili, M. Lomidze","doi":"10.52340/jecm.2021.563","DOIUrl":"https://doi.org/10.52340/jecm.2021.563","url":null,"abstract":"Hyperhidrosis represents pathology of eccrine sweat glands and is manifested by the skin excessive sweating. For patients, living along with hyperhidrosis represents a big challenge, which has a significant impact on numerous aspects of everyday life, as well as on the social and professional lifestyle and psycho-emotional health.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88821932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NEGATIVE/DELETERIOUS EFFECTS OF FASHION ON HEALTH 时尚对健康的负面/有害影响
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-10-11 DOI: 10.52340/jecm.2021.554
Afa Ansari, Prerna Thakur, T. Peshkova, S. Beridze, S. Glonti, I. Nakashidze, R. Vadachkoria
{"title":"NEGATIVE/DELETERIOUS EFFECTS OF FASHION ON HEALTH","authors":"Afa Ansari, Prerna Thakur, T. Peshkova, S. Beridze, S. Glonti, I. Nakashidze, R. Vadachkoria","doi":"10.52340/jecm.2021.554","DOIUrl":"https://doi.org/10.52340/jecm.2021.554","url":null,"abstract":"People are surrounded with unrealistic images that are altered and manipulated to appear \"perfect\" and when they compare themselves with such images, they develop feelings of Self-doubt and believe they should change certain physical aspects to be considered attractive. Therefore, we aimed to evaluate the influence of unrealistic beauty standards set up by the Fashion industry and its effects on a person's physical and mental Wellbeing. We conducted a survey questionnaire targeted at approximately 224 young adults with a mean age of 20-30 years. As a result, 95.6% of our survey respondents agreed that the fashion industry has set up unrealistic beauty standards that deleteriously affect a person's general health and Wellbeing.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78391751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PROBLEMATIC ISSUES IN THE EVALUATION OF MOLECULAR CHARACTERISTICS AND POTENTIAL NEOPLASTIC TRANSFORMATION OF CERVICAL METAPLASIA 宫颈化生的分子特征及潜在肿瘤转化评价中的问题
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-10-11 DOI: 10.52340/jecm.2021.558
T. Svanadze, M. Gachechiladze, G. Burkadze
{"title":"PROBLEMATIC ISSUES IN THE EVALUATION OF MOLECULAR CHARACTERISTICS AND POTENTIAL NEOPLASTIC TRANSFORMATION OF CERVICAL METAPLASIA","authors":"T. Svanadze, M. Gachechiladze, G. Burkadze","doi":"10.52340/jecm.2021.558","DOIUrl":"https://doi.org/10.52340/jecm.2021.558","url":null,"abstract":"Metaplasia represents the replacement of one differentiated cell type with another differentiated cell type, which is frequently seen in uterine cervix, particularly in endocervical epithelium. There are many different types of metaplasia in endocervix. It is suggested that metaplasia represents the fertile soil for the development of neoplasia. However, which cases of metaplasia transform into neoplasia, which type of metaplasia is more realted to neoplastic transformation or if there are some molecular markers which can predict the potential of neoplastic transformation, are nowadays less known. Current review represents the critical discussion of the available literature with regards to the evaluation of molecular markers and the potential of neoplastic transformation in cervical metaplasia.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84747356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
PROBLEMATIC ISSUES IN THE EVALUATION OF PHENOTYPIC PROGNOSTIC MARKERS IN OVARIAN GERM-CELL TUMORS 卵巢生殖细胞肿瘤表型预后标志物评估中的问题
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-10-11 DOI: 10.52340/jecm.2021.550
Nino Tavdgiridze, G. Tevdorashvili, G. Burkadze
{"title":"PROBLEMATIC ISSUES IN THE EVALUATION OF PHENOTYPIC PROGNOSTIC MARKERS IN OVARIAN GERM-CELL TUMORS","authors":"Nino Tavdgiridze, G. Tevdorashvili, G. Burkadze","doi":"10.52340/jecm.2021.550","DOIUrl":"https://doi.org/10.52340/jecm.2021.550","url":null,"abstract":"Ovarian germ-cell tumors represent about 15-20% of all ovarian tumors. They are characterised with high histological and clinical heterogeneity. Ovarian germ-cell tumors can be both benign and malignant. Nowadays, the prognostic markers of ovarian germ-cell tumors are less studied. In particular, there is only limited information about the phenotypic determinants of the malignant transformation of benign germ-cell tumors, as well as lack of information about the relapse development after treatment of malignant germ-cell tumors. In presented review article, the detailed cahracteristics of ovarian germ-cell tumors and the problematic issues in the determination of their prognostic features are discussed.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80538706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CONDITION OF THE ORAL CAVITY OF SOCIALLY VULNERABLE CHILDREN LIVING IN BATUMI 居住在巴统的社会弱势儿童的口腔状况
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-10-11 DOI: 10.52340/jecm.2021.559
S. Davitadze, Qetevan Franchuk, Z. Chomakhashvili, M. Phutkaradze, N. Zosidze, Ruslan Bolkvadze, Demur Jincharadze
{"title":"CONDITION OF THE ORAL CAVITY OF SOCIALLY VULNERABLE CHILDREN LIVING IN BATUMI","authors":"S. Davitadze, Qetevan Franchuk, Z. Chomakhashvili, M. Phutkaradze, N. Zosidze, Ruslan Bolkvadze, Demur Jincharadze","doi":"10.52340/jecm.2021.559","DOIUrl":"https://doi.org/10.52340/jecm.2021.559","url":null,"abstract":"Based on all discussed, we can clearly indicate that in the city of Batumi, the oral - health of children, coming from socially vulnerable families, are not satisfactory, which at the later stage leads to several diseases. The reasons behind this development are the followings: the low educational rate and non-accessibility to dental and financial assistance services. Recommendations for overcoming this problem include: 1. Increasing accessibility to dental services; 2. Providing high quality medical services, in general; 3. Establishing State - Private cooperation model.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88670814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BILIARY COMPLICATIONS AFTER ORTHOPEDIC LIVER TRANSPLANTATION (LITERATURE REVIEW) 骨科肝移植术后胆道并发症(文献复习)
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-07-07 DOI: 10.52340/JECMJ.2021.377
Ruslan Bolkvadze, K. Kashibadze, Alexander Tsalughelashvili, Z. Chomakhashvili, O. Tsetskhladze, Giorgi Zhghenti, N. Zosidze, Demur Jintcharadze
{"title":"BILIARY COMPLICATIONS AFTER ORTHOPEDIC LIVER TRANSPLANTATION (LITERATURE REVIEW)","authors":"Ruslan Bolkvadze, K. Kashibadze, Alexander Tsalughelashvili, Z. Chomakhashvili, O. Tsetskhladze, Giorgi Zhghenti, N. Zosidze, Demur Jintcharadze","doi":"10.52340/JECMJ.2021.377","DOIUrl":"https://doi.org/10.52340/JECMJ.2021.377","url":null,"abstract":"Since 1967, liver transplantation has been considered to be a standard surgical intervention in patients with terminal stage of liver disease, orthopedic liver transplantation is characterized by a number of complications, which can be fatal for the patient. One of the most important post-transplant complications of the liver is biliary complications - the so-called Achilles tendon for liver transplantation. The article discusses current issues in the treatment, diagnosis and prevention of biliary complications, which will allow us to treat patients with these incurable complications more quickly and effectively.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75546828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BEHAVIORAL SLEEP PROBLEMS IN CHILDREN (BEHAVIORAL INSOMNIA) AND EFFECTIVE METHODS OF THEIR MANAGEMENT 儿童行为性睡眠问题(行为性失眠)及其有效管理方法
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-07-07 DOI: 10.52340/JECMJ.2021.389
G. Arveladze, Teimuraz Mikeladze
{"title":"BEHAVIORAL SLEEP PROBLEMS IN CHILDREN (BEHAVIORAL INSOMNIA) AND EFFECTIVE METHODS OF THEIR MANAGEMENT","authors":"G. Arveladze, Teimuraz Mikeladze","doi":"10.52340/JECMJ.2021.389","DOIUrl":"https://doi.org/10.52340/JECMJ.2021.389","url":null,"abstract":"Sleep problems with behavioral origins occur in 20 to 30 percent of children and are especially common in children with medical, neurodevelopmental, or psychiatric disorders. Insomnia related to learned sleep onset associations is most common in infants and toddlers and is characterized by prolonged night waking, requiring parental intervention to restore sleep. It occurs when the child learns to associate falling asleep with specific experiences, such as being rocked or fed. Insomnia related to inadequate limit-setting is a disorder most common in children who are preschool-aged and older and is characterized by active resistance, verbal protests, and repeated demands at bedtime. Guidance to parents about healthy sleep practices helps to prevent sleep problems and is also an important first step in treatment. An integral part of the bedtime routine is the institution of a bedtime and sleep schedule that ensures a developmentally appropriate amount of sleep. A consistent nightly bedtime will help to set the circadian clock and enable the child to fall asleep more easily. Treatment of primary insomnia in older children and adolescents usually involves behavioral interventions that resemble those used in adults. Establishing a consistent sleep schedule is also important for older children and adolescents for whom poor sleep hygiene is a common cause of sleep problems. Pharmacologic therapy for the treatment of childhood insomnia is not a first-line treatment and should always be combined with behavioral therapy.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83356971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STUDY OF VARIABILITY IN THE ACTIVITY OF RIBOSOMAL CISTRONES IN COLORECTAL CANCER 结直肠癌中核糖体顺酮活性变异性的研究
EXPERIMENTAL & CLINICAL MEDICINE GEORGIA Pub Date : 2021-07-07 DOI: 10.52340/JECMJ.2021.382
Nino Chigvinadze, I. Pantsulaia, T. Jokhadze
{"title":"STUDY OF VARIABILITY IN THE ACTIVITY OF RIBOSOMAL CISTRONES IN COLORECTAL CANCER","authors":"Nino Chigvinadze, I. Pantsulaia, T. Jokhadze","doi":"10.52340/JECMJ.2021.382","DOIUrl":"https://doi.org/10.52340/JECMJ.2021.382","url":null,"abstract":"According to the World Health Organization, colon cancer is one of the most common cancers. By 2020, approximately 1,900,000 cases of CRC were detected worldwide (a total of 10%). In 2020, American Cancer Society 104,610 new cases of CRC were identified and 53,200 patients died. Similar to other tumors colon cancer (CRC) is a genetically inherited multifactorial disease. It is established that genetic, immunologic, as well as environmental factors, all play significant role in CRC development and metastasis. As mentioned, carcinogenesis is associated with the whole number of genetic phenomena ongoing in certain groups of the genes; it is of staged nature and includes interactions of gene suppressors and oncogenes. Many genes responsible for CRC development were identified, family forms were described as well. In particular, high risk of CRC development in case of family history of adenomatous polyposis was demonstrated. As mentioned, neoplastic variability of the tumors is associated with changed morphogenesis of the nucleus, in turn, playing certain role in regulation of the suppressor genes p53, APC and pro-carcinogenesis KRAS.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87887963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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