{"title":"卵巢生殖细胞肿瘤表型预后标志物评估中的问题","authors":"Nino Tavdgiridze, G. Tevdorashvili, G. Burkadze","doi":"10.52340/jecm.2021.550","DOIUrl":null,"url":null,"abstract":"Ovarian germ-cell tumors represent about 15-20% of all ovarian tumors. They are characterised with high histological and clinical heterogeneity. Ovarian germ-cell tumors can be both benign and malignant. Nowadays, the prognostic markers of ovarian germ-cell tumors are less studied. In particular, there is only limited information about the phenotypic determinants of the malignant transformation of benign germ-cell tumors, as well as lack of information about the relapse development after treatment of malignant germ-cell tumors. In presented review article, the detailed cahracteristics of ovarian germ-cell tumors and the problematic issues in the determination of their prognostic features are discussed.","PeriodicalId":12081,"journal":{"name":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","volume":"104 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"PROBLEMATIC ISSUES IN THE EVALUATION OF PHENOTYPIC PROGNOSTIC MARKERS IN OVARIAN GERM-CELL TUMORS\",\"authors\":\"Nino Tavdgiridze, G. Tevdorashvili, G. Burkadze\",\"doi\":\"10.52340/jecm.2021.550\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Ovarian germ-cell tumors represent about 15-20% of all ovarian tumors. They are characterised with high histological and clinical heterogeneity. Ovarian germ-cell tumors can be both benign and malignant. Nowadays, the prognostic markers of ovarian germ-cell tumors are less studied. In particular, there is only limited information about the phenotypic determinants of the malignant transformation of benign germ-cell tumors, as well as lack of information about the relapse development after treatment of malignant germ-cell tumors. In presented review article, the detailed cahracteristics of ovarian germ-cell tumors and the problematic issues in the determination of their prognostic features are discussed.\",\"PeriodicalId\":12081,\"journal\":{\"name\":\"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA\",\"volume\":\"104 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-10-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52340/jecm.2021.550\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EXPERIMENTAL & CLINICAL MEDICINE GEORGIA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52340/jecm.2021.550","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
PROBLEMATIC ISSUES IN THE EVALUATION OF PHENOTYPIC PROGNOSTIC MARKERS IN OVARIAN GERM-CELL TUMORS
Ovarian germ-cell tumors represent about 15-20% of all ovarian tumors. They are characterised with high histological and clinical heterogeneity. Ovarian germ-cell tumors can be both benign and malignant. Nowadays, the prognostic markers of ovarian germ-cell tumors are less studied. In particular, there is only limited information about the phenotypic determinants of the malignant transformation of benign germ-cell tumors, as well as lack of information about the relapse development after treatment of malignant germ-cell tumors. In presented review article, the detailed cahracteristics of ovarian germ-cell tumors and the problematic issues in the determination of their prognostic features are discussed.