European RadiologyPub Date : 2025-01-01Epub Date: 2024-07-12DOI: 10.1007/s00330-024-10936-9
Lukas Müller
{"title":"AI-based body composition measures in abdominal CT scans: prime time for clinical implementation?","authors":"Lukas Müller","doi":"10.1007/s00330-024-10936-9","DOIUrl":"10.1007/s00330-024-10936-9","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"517-519"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141590018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
European RadiologyPub Date : 2025-01-01Epub Date: 2024-07-12DOI: 10.1007/s00330-024-10896-0
Eva M Fallenberg
{"title":"Implementing the advantages of contrast-enhanced mammography and contrast-enhanced breast MRI in breast cancer staging.","authors":"Eva M Fallenberg","doi":"10.1007/s00330-024-10896-0","DOIUrl":"10.1007/s00330-024-10896-0","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"160-162"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141590022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
European RadiologyPub Date : 2025-01-01Epub Date: 2024-07-13DOI: 10.1007/s00330-024-10938-7
Yi Xiang Tay, Shane Foley, Ronan Killeen, Marcus E H Ong, Robert Chun Chen, Lai Peng Chan, May San Mak, Jonathan P McNulty
{"title":"Impact and effect of imaging referral guidelines on patients and radiology services: a systematic review.","authors":"Yi Xiang Tay, Shane Foley, Ronan Killeen, Marcus E H Ong, Robert Chun Chen, Lai Peng Chan, May San Mak, Jonathan P McNulty","doi":"10.1007/s00330-024-10938-7","DOIUrl":"10.1007/s00330-024-10938-7","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this systematic review was to offer a comprehensive overview and explore the associated outcomes from imaging referral guidelines on various key stakeholders, such as patients and radiologists.</p><p><strong>Materials and methods: </strong>An electronic database search was conducted in Medline, Embase and Web of Science to retrieve citations published between 2013 and 2023. The search was constructed using medical subject headings and keywords. Only full-text articles and reviews written in English were included. The quality of the included papers was assessed using the mixed methods appraisal tool. A narrative synthesis was undertaken for the selected articles.</p><p><strong>Results: </strong>The search yielded 4384 records. Following the abstract, full-text screening, and removal of duplication, 31 studies of varying levels of quality were included in the final analysis. Imaging referral guidelines from the American College of Radiology were most commonly used. Clinical decision support systems were the most evaluated mode of intervention, either integrated or standalone. Interventions showed reduced patient radiation doses and waiting times for imaging. There was a general reduction in radiology workload and utilisation of diagnostic imaging. Low-value imaging utilisation decreased with an increase in the appropriateness of imaging referrals and ratings and cost savings. Clinical effectiveness was maintained during the intervention period without notable adverse consequences.</p><p><strong>Conclusion: </strong>Using evidence-based imaging referral guidelines improves the quality of healthcare and outcomes while reducing healthcare costs. Imaging referral guidelines are one essential component of improving the value of radiology in the healthcare system.</p><p><strong>Clinical relevance statement: </strong>There is a need for broader dissemination of imaging referral guidelines to healthcare providers globally in tandem with the harmonisation of the application of these guidelines to improve the overall value of radiology within the healthcare system.</p><p><strong>Key points: </strong>The application of imaging referral guidelines has an impact and effect on patients, radiologists, and health policymakers. The adoption of imaging referral guidelines in clinical practice can impact healthcare costs and improve healthcare quality and outcomes. Implementing imaging referral guidelines contributes to the attainment of value-based radiology.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"532-541"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
European RadiologyPub Date : 2025-01-01Epub Date: 2024-07-16DOI: 10.1007/s00330-024-10942-x
Deliah Weiß, Martin Beeres, Ulrich Rochwalsky, Thomas J Vogl, Rolf Schlößer
{"title":"Radiation exposure and estimated risk of radiation-induced cancer from thoracic and abdominal radiographs in 1307 neonates.","authors":"Deliah Weiß, Martin Beeres, Ulrich Rochwalsky, Thomas J Vogl, Rolf Schlößer","doi":"10.1007/s00330-024-10942-x","DOIUrl":"10.1007/s00330-024-10942-x","url":null,"abstract":"<p><strong>Objective: </strong>This study examined radiation exposure and the possible risk of radiation-induced cancer in a large sample of newborn and premature patients.</p><p><strong>Material and methods: </strong>In this retrospective study, we included all hospitalised neonates treated at our university hospital who received at least one X-ray examination from 1 January 2013 to 31 December 2018. We evaluated the dose area product (DAP), effective dose (ED), and estimated risk. The International Commission on Radiological Protection Publication 60 defines values (2.8-13 × 10<sup>-2 </sup>Sv<sup>-1</sup>) to calculate the estimated risk in relation to the ED.</p><p><strong>Results: </strong>Of the 3843 patients (aged 241.1 ± 35.45 days) treated in the neonatal care unit, 1307 (34%) received at least one X-ray. The mean number of X-ray examinations per patient was 3.19 and correlated negatively with birth weight. The mean cumulative DAP was 5.9 mGy*cm<sup>2</sup>, and the cumulative ED was 23.7 µSv per hospital stay. Patients with a birth weight of < 1000 g showed the highest cumulative ED and DAP (p < 0.001). Patients with a birth weight of < 2500 g had the highest ED and DAP per image (p < 0.001). The highest radiation exposure (ED/DAP) occurred for thoracic/abdominal examinations, especially for neonates < 500 g (p < 0.001).</p><p><strong>Conclusion: </strong>There is a strong correlation between immaturity, the number of X-ray examinations, and radiation exposure. The total exposure was minimal, and the number of X-rays per patient has been decreasing in recent years.</p><p><strong>Clinical relevance: </strong>Possible risks to newborns and premature infants caused by ionising X-rays are often the subject of scientific and clinical discussion. Nevertheless, conventional X-ray imaging remains a frequently used tool, and total exposure remains at a very low level.</p><p><strong>Key points: </strong>The number of X-rays per patient has been decreasing in a large university hospital. Half of all patients received only one X-ray; most had a birth weight over 1500 g. This radiation risk can be classified as 'minimal' for patients with a birth weight of < 500 g and as 'negligible' for others.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"297-308"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
European RadiologyPub Date : 2025-01-01Epub Date: 2024-07-16DOI: 10.1007/s00330-024-10939-6
Roberta Eufrasia Ledda, Georg-Christian Funk, Nicola Sverzellati
{"title":"The pros and cons of lung cancer screening.","authors":"Roberta Eufrasia Ledda, Georg-Christian Funk, Nicola Sverzellati","doi":"10.1007/s00330-024-10939-6","DOIUrl":"10.1007/s00330-024-10939-6","url":null,"abstract":"<p><p>Several trials have shown that low-dose computed tomography-based lung cancer screening (LCS) allows a substantial reduction in lung cancer-related mortality, carrying the potential for other clinical benefits. There are, however, some uncertainties to be clarified and several aspects to be implemented to optimize advantages and minimize the potential harms of LCS. This review summarizes current evidence on LCS, discussing some of the well-established and potential benefits, including lung cancer (LC)-related mortality reduction and opportunity for smoking cessation interventions, as well as the disadvantages of LCS, such as overdiagnosis and overtreatment. CLINICAL RELEVANCE STATEMENT: Different perspectives are provided on LCS based on the updated literature. KEY POINTS: Lung cancer is a leading cancer-related cause of death and screening should reduce associated mortality. This review summarizes current evidence related to LCS. Several aspects need to be implemented to optimize benefits and minimize potential drawbacks of LCS.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"267-275"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
European RadiologyPub Date : 2025-01-01Epub Date: 2024-07-12DOI: 10.1007/s00330-024-10912-3
Anna S Bader, Linda B Haramati
{"title":"Letter to the Editor: \"Silent myocardial infarction fatty scars detected by coronary calcium score CT scan in diabetic patients without a history of coronary heart disease\".","authors":"Anna S Bader, Linda B Haramati","doi":"10.1007/s00330-024-10912-3","DOIUrl":"10.1007/s00330-024-10912-3","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"215-217"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141590024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of lipoprotein(a) level on cardiac pathologies in diabetes: a cardiac CT study.","authors":"Jiajun Yuan, Xiaoying Ding, Wenli Yang, Ziting Lan, Yarong Yu, Lihua Yu, Xu Dai, Yufan Wang, Jiayin Zhang","doi":"10.1007/s00330-024-10903-4","DOIUrl":"10.1007/s00330-024-10903-4","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to explore the imaging profile of coronary atherosclerosis, perivascular inflammation, myocardial perfusion, and interstitial fibrosis in diabetes stratified by lipoprotein(a) [Lp(a)] levels.</p><p><strong>Methods: </strong>In this prospective study, we enrolled diabetic patients who had undergone computed tomography (CT) angiography, stress CT-myocardial perfusion imaging, and late iodine enhancement in 20 months. Then, we categorized them into elevated and normal groups based on an Lp(a) cutoff level of 30 mg/dL. All imaging data, including coronary atherosclerosis parameters, pericoronary adipose tissue (PCAT) density, stress myocardial blood flow (MBF), and extracellular volume (ECV), were collected for further analysis.</p><p><strong>Results: </strong>In total, 207 participants (mean age: 59.1 ± 12.0 years, 111 males) were included in this study. Patients with elevated Lp(a) level had more pronounced percent atheroma volume (2.55% (1.01-9.01%) versus 1.30% (0-4.95%), p = 0.010), and demonstrated a higher incidence of positive remodeling, spotty calcification, and high-risk plaque (HRP) than those with normal Lp(a) levels (75.6% versus 54.8%, p = 0.015; 26.8% versus 9.6%, p = 0.003; 51.2% versus 30.1%, p = 0.011, respectively). Results of the multivariate analysis revealed that after adjusting for all clinical characteristics, elevated Lp(a) levels were an independent parameter associated with HRP (odds ratio = 2.608; 95% confidence interval: 1.254-5.423, p = 0.010). However, no significant difference was found between the two groups in terms of PCAT density, stress MBF, and ECV.</p><p><strong>Conclusions: </strong>Elevated Lp(a) levels are associated with extensive coronary atherosclerosis and HRP development. However, they are not related to perivascular inflammation, decreased myocardial perfusion, and interstitial fibrosis in diabetes.</p><p><strong>Clinical relevance statement: </strong>Elevated lipoprotein(a) levels are associated with extensive coronary atherosclerosis and a high incidence of HRPs. However, they are not related to perivascular inflammation, decreased myocardial perfusion, and interstitial fibrosis in diabetes.</p><p><strong>Key points: </strong>Diabetes is a known risk factor that accelerates cardiovascular disease progression. Diabetics with elevated lipoprotein(a) (Lp(a)) levels had a higher percent atheroma volume and positive remodeling, spotty calcification, and HRPs. Patients with diabetes should be screened for elevated Lp(a) using CCTA for comprehensive evaluation of atherosclerotic characteristics.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"220-231"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141590029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
European RadiologyPub Date : 2025-01-01Epub Date: 2024-07-09DOI: 10.1007/s00330-024-10919-w
Yun Hwa Roh, Sae Rom Chung, Su Jeong Yang, Jung Hwan Baek, Young Jun Choi, Tae-Yon Sung, Dong Eun Song, Tae Yong Kim, Jeong Hyun Lee
{"title":"Enhancement on CT for preoperative diagnosis of metastatic lymph nodes in thyroid cancer: a comparison across experience levels.","authors":"Yun Hwa Roh, Sae Rom Chung, Su Jeong Yang, Jung Hwan Baek, Young Jun Choi, Tae-Yon Sung, Dong Eun Song, Tae Yong Kim, Jeong Hyun Lee","doi":"10.1007/s00330-024-10919-w","DOIUrl":"10.1007/s00330-024-10919-w","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the diagnostic performance and interobserver agreement of quantitative CT parameters indicating strong lymph node (LN) enhancement in differentiated thyroid cancer (DTC), comparing them with qualitative analysis by radiologists of varying experience.</p><p><strong>Materials and methods: </strong>This study included 463 LNs from 399 patients with DTC. Three radiologists independently analyzed strong LN enhancement on CT. Qualitative analysis of strong enhancement was defined as LN cortex showing greater enhancement than adjacent muscles on the arterial phase. Quantitative analysis included the mean attenuation value (MAV) of LN on arterial phase (LN<sub>A</sub>) and venous phase (LN<sub>V</sub>), LN<sub>A</sub> normalized to the common carotid artery (NAV<sub>CCA</sub>), internal jugular vein (NAV<sub>IJV</sub>), and sternocleidomastoid muscle (NAV<sub>SCM</sub>), attenuation difference [AD; (LN<sub>A</sub> - MAV<sub>SCM</sub>)], and relative washout ratio [((LN<sub>A</sub> - LN<sub>V</sub>)/LN<sub>A</sub>) × 100]. The interobserver agreement and diagnostic performance of the quantitative and qualitative analyses were evaluated.</p><p><strong>Results: </strong>Interobserver agreement was excellent for all quantitative CT parameters (ICC, 0.83-0.94) and substantial for qualitative assessment (κ = 0.61). All CT parameters except for LN<sub>V</sub> showed good diagnostic performance for metastatic LNs (AUC, 0.81-0.85). NAV<sub>CCA</sub> (0.85, 95% CI: 0.8-0.9) and AD (0.85, 95% CI: 0.81-0.89) had the highest AUCs. All quantitative parameters except for NAV<sub>IJV</sub> had significantly higher AUCs than qualitative assessments by inexperienced radiologists, with no significant difference from assessments by an experienced radiologist.</p><p><strong>Conclusion: </strong>Quantitative assessment of LN enhancement on arterial phase CT showed higher interobserver agreement and AUC values than qualitative analysis by inexperienced radiologists, supporting the need for a standardized quantitative CT parameter-based model for determining strong LN enhancement.</p><p><strong>Clinical relevance statement: </strong>When assessing strong LN enhancement in DTC, quantitative CT parameters indicating strong enhancement can improve interobserver agreement, regardless of experience level. Therefore, the development of a standardized diagnostic model based on quantitative CT parameters might be necessary.</p><p><strong>Key points: </strong>Accurate preoperative assessment of LN metastasis in thyroid cancer is crucial. Quantitative CT parameters indicating strong LN enhancement demonstrated excellent interobserver agreement and good diagnostic performance. Quantitative assessment of contrast enhancement offers a more objective model for the identification of metastatic LNs.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"20-28"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
European RadiologyPub Date : 2025-01-01Epub Date: 2024-10-28DOI: 10.1007/s00330-024-11121-8
Fiorentino Grasso, Francesco Raimondi
{"title":"Radiation exposure and estimated cancer risk in neonates: a cautionary perspective.","authors":"Fiorentino Grasso, Francesco Raimondi","doi":"10.1007/s00330-024-11121-8","DOIUrl":"10.1007/s00330-024-11121-8","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"309-310"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}