Francesco Andrea Causio, Flavia Beccia, Diego Maria Tona, Alessandra Verduchi, Antonio Cristiano, Giovanna Elisa Calabrò, Roberta Pastorino, Carla van El, Stefania Boccia
{"title":"Public perceptions and engagement in mHealth: a European survey on attitudes toward health apps use and data sharing.","authors":"Francesco Andrea Causio, Flavia Beccia, Diego Maria Tona, Alessandra Verduchi, Antonio Cristiano, Giovanna Elisa Calabrò, Roberta Pastorino, Carla van El, Stefania Boccia","doi":"10.1093/eurpub/ckaf036","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf036","url":null,"abstract":"<p><p>This study investigates public perceptions and engagement with mobile health (mHealth) across eight European countries: Italy, the Netherlands, France, Germany, Spain, Poland, Romania, and Hungary. The focus is on attitudes toward health app usage and data sharing, addressing data privacy and security concerns while highlighting generational and educational differences. A cross-sectional survey was conducted with 6581 participants from the selected countries. The survey assessed current usage of health apps, interest in future use, willingness to share health data, and concerns about data privacy. Demographic factors such as age, education level, and geographical location were analyzed to determine their influence on mHealth engagement. The survey revealed that 21.87% of respondents currently use health apps, while 42.71% expressed interest in future use. Regarding data sharing, 52.82% were willing to share health data with healthcare providers, and 25.48% with public and private research institutions. However, concerns about data misuse (72.34%) and hacking (63.68%) were prevalent. Significant generational differences emerged, with older generations showing lower adoption rates of health apps. Education level was a key factor; individuals with tertiary education were more likely to use health apps and demand transparency. The findings emphasize the need for targeted strategies to improve digital literacy, address privacy concerns, and ensure equitable access to mHealth technologies across Europe. Tailored interventions are essential to bridge generational and educational gaps in mHealth engagement while fostering trust in data security measures.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam Mitchell, Mariam Hassan, Fredrik Kahn, Yana Litins'ka, Matilda Almgren, Ulf Malmqvist, Per-Olof Östergren, Malin Inghammar, Jonas Björk, Louise Bennet
{"title":"Barriers and motivators associated with COVID-19 vaccination-a vaccine acceptance scoring system based on a population survey in southern Sweden.","authors":"Adam Mitchell, Mariam Hassan, Fredrik Kahn, Yana Litins'ka, Matilda Almgren, Ulf Malmqvist, Per-Olof Östergren, Malin Inghammar, Jonas Björk, Louise Bennet","doi":"10.1093/eurpub/ckaf030","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf030","url":null,"abstract":"<p><p>Low vaccination coverage against SARS-CoV-2 (COVID-19) is a public health concern. The aim of this study was to identify barriers and motivators associated with COVID-19 vaccination and develop a vaccine acceptance scoring system. From the overall population residing in Skåne county Sweden in 2022 (n = 1 384 531), 3600 randomly selected individuals (aged ≥18 years) received a survey. Questions were grouped into six domains reflecting trust in vaccines and institutions, benefit-risk balance, injunctive and descriptive norms and accessibility. Responses were scored as either assenting (1 p) or dissenting (0 p) in relation to its domain. A score between 1 and 5 p was constructed for each domain and a total vaccine acceptance score was analysed. Internal consistency overall and within domains was assessed with Cronbach's alpha. Associations with vaccination status and vaccine acceptance scores in relation to domains were modelled with logistic regression. 820 responses were received, 646 vaccinated (response rate 36%), and 174 unvaccinated (response rate 10%), with relatively high internal consistency overall (α = 0.76). Domains markedly associated with vaccination were injunctive norms OR 5.06 (95% CI 3.27, 7.83), descriptive norms OR 2.64 (1.63, 4.30) and trust in vaccines OR 1.66 (1.15, 2.40). Vaccine acceptance was measured with sufficient reliability in a Swedish population. Norms, in this context, general perceptions of acceptable/unacceptable behaviours and notion on actual performed behaviours, were together with trust in vaccines most strongly associated with vaccination. Future pandemic responses should consider these aspects in communication strategies and targeted interventions to increase and equalize vaccination uptake.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inna K Lisko, Olli Kurkela, Annele Urtamo, Jenni K Kulmala, Leena P Forma
{"title":"Functional limitations in 2004-22 among Europeans aged 55-69 years: time trends according to labor market group and impacts of the COVID-19 pandemic.","authors":"Inna K Lisko, Olli Kurkela, Annele Urtamo, Jenni K Kulmala, Leena P Forma","doi":"10.1093/eurpub/ckaf054","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf054","url":null,"abstract":"<p><p>In terms of work ability, impacts of the Coronavirus disease 2019 (COVID-19) pandemic on functional ability warrant investigation. The aim is to explore trends in functional limitations in 2004-22 focusing on the impacts of the pandemic among older working-aged Europeans in different labor market groups and at different levels of COVID-19 stringency policies. Data come from the Survey of Health, Ageing and Retirement in Europe (SHARE) collected in 2004-22. Individuals aged 55-69 years from 27 countries were included (N = 245 060). Outcome was functional limitations (Global Activity Limitation Index). Generalized estimating equations were used to analyze time trends and COVID-19 impacts within labor market groups and at different levels of COVID-19 stringency policies. In 2004-22, the likelihood of functional limitations increased slightly among men but remained the same among women. Functional limitations were more likely in countries with low and moderate as compared to high COVID-19 stringency (which represents mostly Southern Europe) in both women and men. During the ∼1st year of the pandemic, likelihood of functional limitations decreased especially in countries with moderate COVID-19 stringency. Decreases were observed in all labor market groups. During the ∼2nd year of the pandemic, the likelihood of functional limitations increased in time but not statistically significantly in most groups. Policymakers should be aware of trends in functional limitations and the impacts of policy decisions while pursuing to prolong work careers. Further investigation is required to verify our findings and to explore underlying reasons behind the decreases in functional limitations after the pandemic.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends and future directions in childhood obesity research in the Nordic countries: a scientometric review.","authors":"Fereshteh Baygi, Kimiya Gohari, Shirin Djalalinia, Jeanette Reffstrup Christensen, Jesper Bo Nielsen, Jens Søndergaard","doi":"10.1093/eurpub/ckaf053","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf053","url":null,"abstract":"<p><p>In the Nordic countries, about one in five children aged 5-18 years live with overweight or obesity. This scientometric review analyses the patterns of childhood obesity research in the Nordic region to inform future strategic decisions for researchers and policymakers. Using VOSviewer (version 1.6.20), we conducted a visualization analysis of Nordic childhood obesity literature from Scopus, covering publication up to February 2024. Additionally, R version 4.4.0, and Microsoft Excel 2016 were used to support further analysis. The analysis included trends of scientific outputs, citations, patterns, collaboration network, and leading institutions. In the Nordic countries, 4123 documents were published from 1981 to 2024. A consistent increase was identified in collaborative studies since 1981. Sweden is playing a leading role in childhood obesity research. A strong partnership was noted between Danish and Swedish researchers, as well as between Finnish and Swedish researchers, with Sweden being a central hub of collaboration. The highly cited publications primarily focused on non-pharmacological public health interventions to reduce cardiovascular risk factors. Significant advancement has been achieved in understanding childhood obesity primarily focused on the filed medicine and nursing. Overweight, obesity, and metrics like body mass index have been extensively investigated, but no focus has been placed on medication as treatment. Despite the increasing research in this field, knowledge gaps exist in genetics, molecular biology, emerging pharmacological treatment as well as behavioral and social sciences. Future research should utilize the unique Nordic databases and advanced methods to improve understanding and inform effective public health interventions.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heart failure burden in Kazakhstan among adults: data from Unified National Electronic Healthcare System 2014-19.","authors":"Gulnur Zhakhina, Arnur Gusmanov, Yesbolat Sakko, Sauran Yerdessov, Alessandro Salustri, Anara Abbay, Zhanar Yermakhanova, Denis Vinnikov, Antonio Sarria-Santamera, Oguz Akbilgic, Abduzhappar Gaipov","doi":"10.1093/eurpub/ckaf049","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf049","url":null,"abstract":"<p><p>Heart failure (HF) is a complex clinical syndrome with significant mortality risks, causing an increasing healthcare burden. Globally, 64.3 million prevalent cases were estimated in 2017. This research examines HF epidemiology in the adult population in Kazakhstan, the largest country in Central Asia. The retrospective analysis was performed on data from the Unified National Electronic Health System, involving 526 766 individuals registered with HF between 2014 and 2019. In the cohort, women accounted for 54% and men for 46%, and the majority (87%) were aged 50 or above. The most prevalent comorbid conditions were hypertension (46%), cerebrovascular diseases (32%), and atherosclerotic heart disease (23%). While the incidence rate declined over the observation period, the all-cause mortality rate almost tripled from 356 to 975 people per million population during the observation period. Of the cohort, 14% of the patients (71 591) were recorded as deceased. In 2019, HF in Kazakhstan resulted in the loss of 2364789.8 disability-adjusted life years. Premature death accounted for a major portion, with 1337578.9 years of life lost. Males have a higher risk of death compared to females [hazard ratio (HR) = 1.24, 95% confidence interval (CI): 1.23-1.26]. History of acute myocardial infarction increases the risk of death by 69% (HR = 1.69, 95% CI: 1.67-1.73) and diabetes by 14% (HR = 1.14, 95% CI: 1.12-1.16) after adjustment for other variables. This research evaluated the burden and disability-adjusted life years of HF in Kazakhstan. The results show that more effective disease management systems and preventive measures for the elderly are needed.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier Fagundo-Rivera, María Soledad García-Lozano, Francisco Javier Portero-Prados, Rocío Romero-Castillo, Nadine Badillo-Sánchez, Pablo Fernández-León
{"title":"Barriers to healthcare access for irregular immigrants after their arrival in Spain: a systematic review.","authors":"Javier Fagundo-Rivera, María Soledad García-Lozano, Francisco Javier Portero-Prados, Rocío Romero-Castillo, Nadine Badillo-Sánchez, Pablo Fernández-León","doi":"10.1093/eurpub/ckaf042","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf042","url":null,"abstract":"<p><p>Examining the barriers encountered by irregular immigrants in accessing the public health system is crucial for the continuity of healthcare processes. This approach not only heightens patient-centered care but also fosters long-term public health preparedness and social cohesion. The aim of this review was to examine the existing barriers to accessing the Spanish healthcare system for the immigrant population. A systematic review of original articles was conducted based on the PRISMA methodology. Studies registered in PubMed, Scopus, CINAHL, LILACS, Web of Science, and Enfispo were analyzed. A total of 4773 articles were identified, of which 15 were selected for review. Among the selected articles, 10 employed qualitative methodologies, 1 utilized a mixed methodology, and 4 used quantitative methodologies. A variety of access barriers related to communication, administrative issues, and misinformation about legal aspects were identified. It was noted that one in five immigrants has experienced at least one barrier to accessing the Spanish healthcare system. Barriers to access to the health system are clearly shared by both immigrants and healthcare professionals. Barriers to access to the health system are a result of the coalition of organizational factors, cultural experiences, and socioeconomic and educational determinants. Access to healthcare for irregular migrants in Spain is hindered by language barriers, misinformation, and administrative obstacles, exacerbated by the COVID-19 pandemic. Policies are needed to ensure equitable care, enhance communication, streamline procedures, and strengthen collaboration with non-governmental organizations and cultural mediators to optimize healthcare responses.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna C Svärd, Mari-Liis Kalima, Jaana I Halonen, Minna Mänty, Tero Kujanpää, Eira Roos, Jatta Salmela, Tea Lallukka
{"title":"Joint contributions of psychological distress and demanding working conditions to short and long sickness absence among young and early midlife municipal employees.","authors":"Anna C Svärd, Mari-Liis Kalima, Jaana I Halonen, Minna Mänty, Tero Kujanpää, Eira Roos, Jatta Salmela, Tea Lallukka","doi":"10.1093/eurpub/ckaf048","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf048","url":null,"abstract":"<p><p>This register-linked follow-up study examined whether psychological distress and demanding working conditions are jointly associated with short and long sickness absence (SA) periods among young and midlife Finnish public sector employees. We linked the Helsinki Health Study survey (response rate 51.5%, 80% women, ages 19-39 years in 2017) on psychological distress, physically and mentally strenuous work, and hours per day spent in physical work with the employer's SA register (n = 3609, mean follow-up of 2.1 years). We calculated rate ratios (RRs) and their 95% confidence intervals (CIs) for short (1-7 days) and long (8+ days) SA periods using negative binomial regression models. Additionally, we calculated the synergistic interaction between psychological distress and working conditions. Most (88%) participants had at least one short and 31% at least one long SA period. Participants with psychological distress and exposure to demanding working conditions had the highest RRs for long SA periods (physically strenuous work: RR: 2.27, CI: 1.87-2.77; mentally strenuous work: RR: 2.02, CI: 1.66-2.46; ≥3 h per day spent in physical work: RR: 2.41, CI: 1.94-2.99). The interactions for long SA were negative for physically demanding working conditions, but additive for mentally strenuous work. The associations were weaker for short SA periods. Adjusting for other covariates only slightly attenuated these associations. Psychological distress and demanding working conditions were jointly associated with short and long SA periods. Both individual- and workplace-related risk factors for SA need to be considered when planning preventive actions.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Socioeconomic inequalities and diabetes complications: an analysis of administrative data from Hungary.","authors":"Péter Elek, Balázs Mayer, Orsolya Varga","doi":"10.1093/eurpub/ckaf038","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf038","url":null,"abstract":"<p><p>Diabetes complications are associated with increased healthcare costs and worsened patient outcomes. In this paper, we analyse how individual-level demographic and territorial-level socioeconomic and healthcare variables influence the presence and severity of diabetes complications and their relationship with mortality. Our study utilizes anonymized administrative healthcare data on all diabetes patients of Hungary between 2010 and 2017. We construct settlement-year level and individual-year level panel datasets to analyse diabetes prevalence, incidence and complications, employing Poisson and logit models to explore associations between complications and the explanatory variables. The adapted Diabetes Complications Severity Index (aDCSI) is employed to quantitatively evaluate the severity of complications by aggregating individual complication scores from ICD-10 diagnosis codes. We find that diabetes prevalence and incidence are higher in settlements with above-median unemployment rates, where patients exhibit more severe complications, as shown by higher average aDCSI scores. Among socioeconomic factors, unemployment rate is particularly associated with increased aDCSI scores, while better healthcare access is associated with lower aDCSI scores in unadjusted but with higher scores in adjusted models. The presence and severity of complications, especially renal, cardiovascular and peripheral vascular ones, substantially increase 5-year inpatient mortality. Most of the mortality difference by settlement-level unemployment rate disappears when complications are accounted for. We conclude that socioeconomic inequalities, particularly higher unemployment rates, are strongly linked to diabetes complications and associated mortality risk. Addressing these disparities through improved healthcare accessibility and targeted public health strategies could play a crucial role in reducing the burden of diabetes-related complications and improving patient outcomes.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hana Jaworek, Ondrej Bouska, Pavla Kourilova, Marian Hajduch, Vladimira Koudelakova
{"title":"High-risk HPV prevalence in the Czech cervical cancer screening population: a comparison of clinician-collected and self-collected sampling.","authors":"Hana Jaworek, Ondrej Bouska, Pavla Kourilova, Marian Hajduch, Vladimira Koudelakova","doi":"10.1093/eurpub/ckaf045","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf045","url":null,"abstract":"<p><p>The prevalence of high-risk human papillomavirus (hrHPV) types varies across countries, making it essential to estimate prevalence using nationwide samples. Data on hrHPV prevalence in the Czech Republic are very limited. This study aimed to determine the prevalence of various hrHPV types in an unselected screening population of Czech women aged 30-65 years, using paired clinician-obtained cervical swab (CS) and self-collected cervicovaginal swabs (CVS). A total of 1026 eligible women were recruited into two study arms. In arm A, the digene® HC2 DNA Collection Device was used for both CS and CVS. In arm B, the Evalyn Brush was used for CVS, while the Cervex Brush was used for CS. All samples were tested for hrHPV using the digene® HC2 High-Risk HPV DNA Test and genotyped with the PapilloCheck® HPV-Screening assay. The overall hrHPV prevalence was 14.8%, based on positive results from either CVS or CS samples. hrHPV positivity was detected in 10.8% of clinician-obtained CSs and 11.8% of self-collected CVSs. A combined analysis of CS and CVS samples identified the five most prevalent hrHPV genotypes: HPV16, HPV31, HPV39, HPV56, and HPV68. The comparison of hrHPV detection in paired CS and CVS samples showed an overall concordance of 93%. These findings highlight the importance of detecting hrHPV genotypes alongside conventional Pap testing in national cervical screening programs. Furthermore, the results confirm that self-sampling kits represent a suitable alternative to clinician-collected samples.</p><p><p>Clinical trials registration ClinicalTrials.gov Identifier (NCT04133610).</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Safak Caglayan, Anne Høye, Jens C Thimm, Catharina E A Wang, Ole K Grønli
{"title":"Association of adverse childhood experiences with physical illness and self-rated health in the population-based Tromsø Study.","authors":"Safak Caglayan, Anne Høye, Jens C Thimm, Catharina E A Wang, Ole K Grønli","doi":"10.1093/eurpub/ckaf031","DOIUrl":"https://doi.org/10.1093/eurpub/ckaf031","url":null,"abstract":"<p><p>Adverse childhood experiences (ACEs) are highly prevalent and associated with life-long health consequences. Here, we investigated the relationship of ACEs to adult-onset health outcomes in general population. We conducted a cross-sectional analysis using the seventh survey of the Tromsø Study, including 20 843 participants. Main exposure variables were exposure to at least one ACE, rumination related to adverse experiences, cumulative ACEs, and two clusters of ACEs, i.e. interpersonal and impersonal ACEs. Logistic and ordinal regression models were fitted to estimate the risk of adult-onset physical illness and poor self-rated health adjusted for birth year, sex, smoking, education, and income. We found that exposure to at least one ACE together with rumination was associated with increased risk of hypertension, heart failure, atrial fibrillation, diabetes, obesity, kidney disease, chronic obstructive pulmonary disease, asthma, rheumatoid arthritis, arthrosis, migraine, chronic pain, and poor self-rated health. We observed dose-effect relationships of cumulative ACEs to the aggregated risk of 14 among 16 health outcomes. While increased risk of heart failure, kidney disease, and rheumatoid arthritis was only linked to the interpersonal ACEs, increased risk of coronary artery disease was associated only with the impersonal ACEs. Our findings demonstrate that exposure to ACEs increases the risk of adult-onset physical illness and poor self-rated health in a dose-effect relationship, and rumination related to adverse experiences is associated with an aggravated risk. Inquiry into exposure to ACEs might inform about health risks. Early intervention approaches to promote positive experiences and increase resilience might alleviate life-long health burden.</p>","PeriodicalId":12059,"journal":{"name":"European Journal of Public Health","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}