{"title":"Beyond the mean: The prognostic value of lipid variability in atherosclerosis and mortality.","authors":"Angela Pirillo, Alberico L Catapano","doi":"10.1093/eurjpc/zwaf321","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf321","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gianluigi Guida, Andrea Attanasio, Giandomenico Disabato, Massimo Piepoli
{"title":"The heart of the matter: why cardiovascular prevention needs an environmental revolution.","authors":"Gianluigi Guida, Andrea Attanasio, Giandomenico Disabato, Massimo Piepoli","doi":"10.1093/eurjpc/zwaf238","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf238","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Permissive Hypercreatinaemia and Intensive Blood Pressure Control.","authors":"John P McCormick, John W McEvoy","doi":"10.1093/eurjpc/zwaf311","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf311","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuqi Wang, Samuel Y S Wong, Benjamin H K Yip, Eric K P Lee
{"title":"Developing and validating a diagnostic threshold for central blood pressure in assessing cardiovascular risks.","authors":"Shuqi Wang, Samuel Y S Wong, Benjamin H K Yip, Eric K P Lee","doi":"10.1093/eurjpc/zwaf309","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf309","url":null,"abstract":"<p><strong>Aims: </strong>This study aimed to establish an outcome-derived threshold for central blood pressure (cBP) and evaluate its clinical utility in stratifying cardiovascular (CVD) risk.</p><p><strong>Methods and results: </strong>A retrospective cohort study of 34 289 adults without prior CVD was conducted using the UK Biobank dataset. The primary endpoint was a composite of cardiovascular mortality and non-fatal cardiovascular events. Diagnostic threshold for cBP was developed by bootstrap and approximation methods, based on the current brachial BP. Cox regression models were employed to evaluate the clinical utility of diagnostic thresholds for cBP in predicting in CVD. A diagnostic threshold of 135 mmHg for central systolic blood pressure (SBP) corresponded to the threshold of 140 mmHg for brachial SBP. Simultaneous assessment of brachial and central SBP configurated following categories: brachial and central normotension (49.84%), isolated brachial hypertension (2.23%), isolated central hypertension (3.65%) and concordant brachial and central hypertension (44.28%). Compared with concordant normotension, hazard ratios for cardiovascular events were 0.81 (0.45, 1.44) for isolated brachial hypertension, 1.70 (1.23, 2.35) for isolated central hypertension and 1.51 (1.30, 1.76) for concordant hypertension. The inclusion of cBP improved model fit and discrimination for predicting CVD beyond brachial BP alone.</p><p><strong>Conclusion: </strong>This study established a diagnostic threshold of 135 mmHg for central SBP. Individuals with central HT exhibited elevated risks of CVD, regardless of brachial HT status. Incorporating central BP enhanced the prediction of CVD risk beyond traditional BP measurement alone.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiovascular health: it is never too late.","authors":"Birna Bjarnason-Wehrens, Bernhard Schwaab","doi":"10.1093/eurjpc/zwaf278","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf278","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bastian Schrader, Armin Weers, Burkhard Garmann, Stephan Lüders, Matteo Scorcelletti, Bernhard Vaske, Paul Meyer, Eugen Gehlenborg, Sandra Garstecki, Joachim Schrader, Albrecht Elsässer
{"title":"Football as the champion of cardiovascular prevention: results of the randomized and interventional MY-3F study (Fit & Fun with Football after myocardial infarction or coronary artery disease).","authors":"Bastian Schrader, Armin Weers, Burkhard Garmann, Stephan Lüders, Matteo Scorcelletti, Bernhard Vaske, Paul Meyer, Eugen Gehlenborg, Sandra Garstecki, Joachim Schrader, Albrecht Elsässer","doi":"10.1093/eurjpc/zwaf273","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf273","url":null,"abstract":"<p><strong>Aims: </strong>The MY-3F [Fit & Fun with Football after myocardial infarction (MI) or coronary artery disease (CAD)] study was the first to investigate whether a structured and health-adapted football training programme can improve fitness and risk factors in patients with CAD and whether it is safe. The primary objective of this study was to improve fitness in maximum oxygen uptake in spiroergometry (VO2peak), blood pressure, weight, and safety.</p><p><strong>Methods and results: </strong>The MY-3F study is a prospective randomized interventional study with 1-year follow-up in patients with MI or CAD. A football group (FG, n = 89) completed a structured 'health' football training (1 h/week, 75 min) led by licensed football coaches. The results were compared with a control group (CG, n = 88). VO2peak in the FG significantly increased from 18.0 to 19.7 mL/min/kg (P < 0.001), and VO2peak in the CG significantly decreased from 19.5 to 18.3 mL/min/kg (P = 0.046). In the FG, running performance per participant per training improved from 1.8 km at admission to 2.4 km at the end of study (P < 0.001). In the FG, blood pressure decreased from 132/81 to 125/76 mmHg (P < 0.001). In the CG, it changed slightly from 137/82 to 136/82 mmHg (ns). In addition, a significantly more antihypertensives were given in CG, but not in FB. In the FG, weight decreased from 92.3 to 90.4 kg (P = 0.003). In the CG, it increased slightly from 90.7 to 91 kg (P = 0.6 ns). Depressive symptoms showed a significant improvement in the FG (P = 0.034), but no changes were observed in the CG. There was no significant change in LDL cholesterol in both groups, but significantly more lipid-lowering therapy was administered in the CG (P = 0.049).</p><p><strong>Conclusion: </strong>In My-3F, the preventive benefit on CVRF (cardiovascular risk factors) and fitness of football training in patients after MI or CAD was clearly demonstrated for the first time. The concept proved to be safe and cost-effective and could open the doors of football clubs to evidence-based cardiological prevention.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Childhood Exposure to Multiple Types of Violence and Adult Cardiovascular Disease.","authors":"Cancan Cui, Lin Liu, Zheng Guo, Jiayin Song, Yulu Zheng, Zhenming Zhang, Ning Han, Yitian Qi, Yuanmei Chen, Chunyan Wang, Chen Sheng, Lois Balmer, Zhijia Wang, LinLin Liu, Zhiyuan Wu","doi":"10.1093/eurjpc/zwaf292","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf292","url":null,"abstract":"<p><strong>Aims: </strong>To explore the associations between childhood experience of violence from parents, siblings, and peers and the subsequent risk of cardiovascular disease (CVD) and to examine whether adult depressive symptoms modify these associations.</p><p><strong>Methods and results: </strong>This population-based cohort study used data from the China Health and Retirement Longitudinal Study (CHARLS). Childhood exposures to violence from parents, siblings, and peers were assessed through a life history questionnaire. Depressive symptoms were measured using the validated 10-item Center for Epidemiologic Studies Depression Scale. The primary outcome was self-reported, physician-diagnosed CVD. Multivariate Cox proportional hazards models with age as the time scale were used. The study included 11,398 participants, with a mean (SD) age of 58 (9) years, of whom 5622 (49.3%) were men. Among participants, 1101 (9.7%) reported frequent childhood violence exposure, including violence from parents (623, 5.5%), siblings (117, 1.0%), and peers (515, 4.5%). Frequent exposures to violence from parents, siblings, peers, or any type were associated with increased risks of CVD, with hazard ratios (HRs) of 1.23 (95% CI: 1.04-1.45), 1.24 (0.87-1.75), 1.25 (1.05-1.49), and 1.22 (1.06-1.40), respectively. The associations were consistent across subgroups and multiple sensitivity analyses. Adult depressive symptoms mediated 23.0% of the association between frequent exposure to violence and CVD (P for mediation = 0.03).</p><p><strong>Conclusion: </strong>Childhood exposure to violence from parents, siblings, and peers is associated with an elevated risk of adult-onset CVD. Addressing mental health may help mitigate the long-term CVD risk linked to childhood violence exposure.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sarcopenia : a new cardiovascular risk factor ?","authors":"Olivier Hanon","doi":"10.1093/eurjpc/zwaf282","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf282","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}