European journal of preventive cardiology最新文献

{"title":"Cumulative Blood Pressure Exposure and Global and Regional Cardiac Structure and Function: The MESA Study.","authors":"Soroush Masrouri, Peyman Tabnak, Parag Chevli, Saeid Mirzai, Leandro Slipczuk, Sujethra Vasu, Joao A C Lima, Michael D Shapiro","doi":"10.1093/eurjpc/zwaf163","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf163","url":null,"abstract":"<p><strong>Aims: </strong>This study examined the associations between decade-long cumulative blood pressure (BP) exposure and global/regional myocardial structure and function independent of current BP levels.</p><p><strong>Methods: </strong>We analyzed 3,015 adults (aged 69.0±9.2 years) from the Multi-Ethnic Study of Atherosclerosis (MESA) who underwent cardiac magnetic resonance (CMR) imaging at year 10 (exam 5, 2010-2012). Measures included left ventricular (LV) parameters, global/regional myocardial function via tagged CMR, interstitial myocardial fibrosis (IMF) via T1-mapping measures (native T1 and extracellular volume fraction [ECV]), and myocardial scar via late gadolinium enhancement (LGE). We used cumulative exposure of BP through baseline and up to exam 5 (millimeters of mercury × year) to represent long-term exposure to BP levels. Linear regression, logistic regression, and generalized additive models were used to quantify the association of cumulative BP parameters with measures of cardiac structure and function.</p><p><strong>Results: </strong>Higher cumulative systolic BP (SBP), independent of current SBP, correlated with increased LV mass index (1.93 g/m² per SD), worse global/regional circumferential strain (0.24% to 0.38% lower absolute values per SD), and greater myocardial scar risk (OR: 1.36, 95% CI: 1.02-1.82 per SD). Cumulative diastolic BP (DBP) was associated with circumferential strain, showing nearly J-shaped relationships after adjusting for current DBP (all P < 0.05). In non-hypertensive individuals with BP consistently below the hypertension threshold, cumulative SBP remained significantly associated with LV mass index and strain but not myocardial scar (OR: 1.53, 95% CI: 0.82-2.87, P=0.19).</p><p><strong>Conclusion: </strong>Higher cumulative BP was associated with worse global and regional cardiac structure/function and myocardial scar, independent of a single BP at the time of imaging, and was still observed to some extent in non-hypertensive individuals who consistently maintained blood pressure levels below the hypertension threshold.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The hidden costs of fast travel: aircraft noise and diabetes risk.","authors":"Nicolle Kränkel","doi":"10.1093/eurjpc/zwae394","DOIUrl":"10.1093/eurjpc/zwae394","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"315-316"},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RE: Ambient temperature and risk of cardiovascular and respiratory adverse health outcomes.","authors":"Tomoyuki Kawada","doi":"10.1093/eurjpc/zwae257","DOIUrl":"10.1093/eurjpc/zwae257","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"351"},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regarding the study on workplace sexual harassment and cardiometabolic disease.","authors":"M F Margriet de Beus, M V Maxime van de Griend, K Karianne Kuiper-Meijer, A M Avi Wilson","doi":"10.1093/eurjpc/zwae277","DOIUrl":"10.1093/eurjpc/zwae277","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"352"},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronobiology and cardiovascular disease: the time and temperature matter.","authors":"Andreina Carbone, Francesco Ferrara, Eduardo Bossone","doi":"10.1093/eurjpc/zwae326","DOIUrl":"10.1093/eurjpc/zwae326","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"325-326"},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142375340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midlife Mediterranean Diet is Associated with Subclinical Carotid Atherosclerosis in Late Midlife.","authors":"Albin Dahlin Almevall, Patrik Wennberg, Per Liv, Emma Nyman, Kristina Lindvall, Margareta Norberg, Elin Chorell, Maria Wennberg","doi":"10.1093/eurjpc/zwaf155","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf155","url":null,"abstract":"<p><strong>Aims: </strong>To investigate the association between dietary patterns at ages 40, 50 and 60 and subclinical carotid atherosclerosis at age 60.</p><p><strong>Methods: </strong>Participants that were 60 years of age at the Swedish VIPVIZA (VisualiZation of asymptomatic Atherosclerotic disease) trial baseline (2013-2016) with retrospective VIP (Västerbotten Intervention Programme) dietary data at ages 40, 50, and 60 (n=1034) were included. Dietary patterns were assessed using the Mediterranean Diet Score (MDS) and Healthy Diet Score (HDS), while carotid ultrasound was used to measure carotid artery intima-media thickness (CIMT) and carotid plaque (CP). Multivariable regressions and mediation analysis investigated associations, sex differences and potential mediating factors.</p><p><strong>Results: </strong>High (OR: 0.72, 95% CI: 0.52-0.98) or midrange (OR: 0.74, 95% CI: 0.55-0.99) cumulative MDS for ages 40, 50 and 60, as compared to low, was associated with lower CP presence at age 60. Initial sex-stratified analysis yielded similar, though non-significant, point estimates. Further analysis revealed that the relationship between plaque and MDS seem driven more by women (0.41, 95% CI: 0.237-0.703) while a significant association between CIMT and MDS was only present in men (p < 0.05). HDS during midlife did not show any significant associations with CP or CIMT at age 60.</p><p><strong>Conclusion: </strong>Findings underscore associations of midlife Mediterranean-style diet and lower presence of subclinical carotid atherosclerosis at age 60 and confirm the significance of dietary interventions as potential means for cardiovascular disease prevention. The study enhances understanding of long-term dietary patterns and their link to subclinical atherosclerosis, supporting future interventions and further research.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-rated physical fitness predicts cardiovascular and all-cause mortality - implications for clinical decision-making.","authors":"Angela P Moissl, Graciela E Delgado, Marcus E Kleber, Frank C Mooren, Hendrik Schäfer, Bernhard K Krämer, Winfried März, Boris Schmitz","doi":"10.1093/eurjpc/zwaf154","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf154","url":null,"abstract":"<p><strong>Aims: </strong>The study investigated the association between self-reported physical fitness (SRPF) and mortality in 3,248 participants of the Ludwigshafen Risk and Cardiovascular Health (LURIC) study with a mean follow-up of 9.9 years.</p><p><strong>Methods: </strong>SRPF was inquired using an 11-point Likert scale on a paper-pencil questionnaire at enrolment and we defined five distinct classes. Kaplan-Meier survival analysis and Cox regression models were used to investigate the association with mortality.</p><p><strong>Results: </strong>Participants with higher baseline SRPF had a significantly lower risk of all-cause and cardiovascular mortality. Regarding cardiovascular mortality, participants in the highest SRPF class had the lowest risk with a hazard ratio HR 0.14 (95% CI 0.08-0.24) compared to the lowest SRPF class. These associations remained statistically significant after adjustment for age, sex, hypertension, diabetes mellitus, low-density lipoprotein cholesterol, glycated haemoglobin A1c (HbA1c), smoking, and other confounders, including comorbidities. Similar results were seen in both participants with angiographically documented coronary artery disease (CAD, n=2583, 78%) and those without CAD (n=733; 22%). Higher SRPF was associated with significantly lower systolic blood pressure and resting heart rate as well as lower HbA1c, fasting glucose, serum uric acid and lower inflammatory markers such as hs-CRP, IL-6, and SAA. Conversely, a higher SRPF was associated with higher Apolipoprotein A-2 and HDL-cholesterol concentrations (p<0.001).</p><p><strong>Conclusion: </strong>Our research shows that SRPF is a strong predictor of overall and cardiovascular mortality for individuals with and without CAD. This suggests that SRPF should be part of routine medical check-ups, highlighting the importance of promoting physical activity for cardiovascular health.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Focus issue on environmental and social factors and cardiovascular risk.","authors":"Esmée A Bakker, Victor Aboyans","doi":"10.1093/eurjpc/zwaf120","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf120","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":"32 4","pages":"273-275"},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Asymptomatic Atrial Fibrillation and its Dynamic Aspects.","authors":"Laurent Fauchier, Lisa Lochon, Thibault Lenormand","doi":"10.1093/eurjpc/zwaf144","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf144","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exposure to aircraft noise exacerbates cardiovascular and oxidative damage in three mouse models of diabetes.","authors":"Dominika Mihalikova, Paul Stamm, Miroslava Kvandova, Chinmayi Pednekar, Lea Strohm, Henning Ubbens, Matthias Oelze, Marin Kuntic, Claudius Witzler, Maria Teresa Bayo Jimenez, Sanela Rajlic, Katie Frenis, Qi Tang, Yue Ruan, Susanne Karbach, Hartmut Kleinert, Omar Hahad, Alex von Kriegsheim, Ning Xia, Tilman Grune, Huige Li, Swenja Kröller-Schön, Adrian Gericke, Wolfram Ruf, Philipp S Wild, Philipp Lurz, Thomas Münzel, Andreas Daiber, Thomas Jansen","doi":"10.1093/eurjpc/zwae320","DOIUrl":"10.1093/eurjpc/zwae320","url":null,"abstract":"<p><strong>Aims: </strong>Epidemiology links noise to increased risk of metabolic diseases like diabetes and obesity. Translational studies in humans and experimental animals showed that noise causes reactive oxygen species (ROS)-mediated cardiovascular damage. The interaction between noise and diabetes, specifically potential additive adverse effects, remains to be determined.</p><p><strong>Methods and results: </strong>C57BL/6 mice were treated with streptozotocin (i.p. injections, 50 mg/kg/day for 5 days) to induce type 1 diabetes mellitus, with S961 (subcutaneous osmotic mini-pumps, 0.57 mg/kg/day for 7 days) or fed a high-fat diet (HFD, 20 weeks) to induce type 2 diabetes mellitus. Control and diabetic mice were exposed to aircraft noise to an average sound pressure level of 72 dB(A) for 4 days. While body weight was unaffected, noise reduced insulin production in all diabetes models. The oral glucose tolerance test showed only an additive aggravation by noise in the HFD model. Noise increased blood pressure and aggravated diabetes-induced aortic, mesenteric, and cerebral arterioles' endothelial dysfunction. ROS formation in cerebral arterioles, the aorta, the heart, and isolated mitochondria was consistently increased by noise in all models of diabetes. Mitochondrial respiration was impaired by diabetes and noise, however without additive effects. Noise increased ROS and caused inflammation in adipose tissue in the HFD model. RNA-sequencing data and alteration of gene pathway clusters also supported additive damage by noise in the setting of diabetes.</p><p><strong>Conclusion: </strong>In all three models of diabetes, aircraft noise exacerbates oxidative stress, inflammation, and endothelial dysfunction in mice with pre-existing diabetes. Thus, noise may potentiate the already increased cardiovascular risk in diabetic patients.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"301-314"},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}