European Journal of Nutrition最新文献

{"title":"Serum lipidomic profiles associated with Mediterranean diet in overweight and obese breast cancer survivors: an exploratory study.","authors":"Jae Hwa Lee, Ji Seo Park, Jin Ju Park, Ji-Won Lee, Sang Hui Chu, Hae Won Lee, Young-Ran Yoon, Sook Jin Seong, Mi-Ri Gwon","doi":"10.1007/s00394-026-04108-2","DOIUrl":"10.1007/s00394-026-04108-2","url":null,"abstract":"<p><strong>Purpose: </strong>Among breast cancer (BC) survivors, overweight and obesity increase the risk of recurrence, underscoring the importance of dietary strategies for weight management. The Mediterranean diet (MD) can promote weight loss and reduce lipid levels. Analyzing alterations at the lipid species level can provide more detailed insights into the metabolic benefits associated with the MD. This study aimed to explore lipid remodeling associated with MD adherence in BC survivors through comprehensive lipidomic analysis.</p><p><strong>Methods: </strong>This exploratory ancillary study was conducted as non-randomized, non-controlled pre-post intervention analysis of serum samples collected before and after an 8-week MD intervention from 12 overweight or obese BC survivors. Fasting paired serum samples (n = 24) were used to profile lipid species using ultra-high-performance liquid chromatography-tandem mass spectrometry in both positive and negative ionization modes. Multivariate and correlation analyses were used to assess overall lipidomic alterations. Participants were further classified into maintainer or improver subgroups based on changes in their Mediterranean diet score (MDS), and subgroup-specific lipidomic responses to the MD intervention were examined.</p><p><strong>Results: </strong>Participants showed significant reductions in body weight, waist circumference, and clinical triglyceride levels, along with increased quantitative insulin sensitivity check index and MDS following the MD intervention. Forty-three putative lipid species were identified, predominantly characterized by reductions in triacylglycerols (TGs) enriched with saturated fatty acids. TG 16:0_18:0_18:0 and TG 16:0_18:1_24:0 exhibited strong negative correlations with MDS and positive correlations with insulin resistance markers. Significant lipid remodeling was observed only in the maintainer group.</p><p><strong>Conclusion: </strong>In this exploratory study, adherence to an 8-week MD was associated with changes in body composition, metabolic markers, and the serum lipidomic profile in overweight and obese BC survivors. These findings provide preliminary evidence that MD adherence may be associated with lipidomic and metabolic changes in BC survivors, warranting confirmation in larger, controlled studies.</p><p><strong>Clinical trial registry: </strong>http://clinicaltrials.gov , NCT03581630.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring an energy-density adjustment to the Nutri-Score algorithm for general foods.","authors":"Anna Amberntsson, Mari Mohn Paulsen, Marta Angela Bianchi, Bryndis Eva Birgisdottir, Anja Pia Biltoft-Jensen, Dina Moxness Konglevoll, Anne Lise Brantsaeter, Lene Frost Andersen, Marianne Hope Abel","doi":"10.1007/s00394-026-04105-5","DOIUrl":"10.1007/s00394-026-04105-5","url":null,"abstract":"<p><strong>Purpose: </strong>The Nutri-Score categorizes foods by nutritional value per 100 g or 100 ml, which may lead to poor discriminatory ability for products with low energy density and large portion sizes, like ready-to-eat meals. We hypothesized that adapting the Nutri-Score algorithm to account for variation in energy density could better capture nutritional quality, particularly in lower energy-dense foods like ready meals, without substantially affecting other food scores. The aim of this study was to perform a proof‑of‑concept evaluation of adapting the Nutri-Score algorithm for general foods to different levels of energy density.</p><p><strong>Methods: </strong>This study utilized the Norwegian food databases Tradesolution and Unil (N = 25,813) to compare the energy-adjusted algorithm with the Nutri-Score 2023.</p><p><strong>Results: </strong>The energy-adjusted Nutri-Score shifted food categorizations for 22% of products. Foods with low energy density, such as ready meals, showed increased scoring variation, indicating a more nuanced nutritional quality assessment, as intended. In these foods, we also saw a decline in favourable scores and an increase in unfavourable ones. However, high-energy-density food categories, like cakes and pastries, more often received more favourable scores. Also, the discriminatory ability between low-fat and full-fat products was reduced.</p><p><strong>Conclusion: </strong>While the energy-adjusted Nutri-Score improved scoring differentiation for certain low-energy-density foods, it showed unfavourable side-effects, indicating that overall, it is not superior to the Nutri-Score 2023. Nonetheless, adapting the algorithm to energy density offers potential for improved nutrient profiling methodologies in specific contexts. Further refinement of the weighting system could address observed weaknesses, optimizing this approach for broader application.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health co-benefits of sustainable dietary transitions to reduced red and processed meat intake in the United Kingdom: a modelling study.","authors":"Patricia Eustachio Colombo, Olivia Auclair, James Milner, Angela Fontan, Silvia Pastorino, Sara Monteiro Pires, André Hesselink, Marie Löf, Rosemary Green","doi":"10.1007/s00394-026-04093-6","DOIUrl":"10.1007/s00394-026-04093-6","url":null,"abstract":"<p><strong>Purpose: </strong>Reducing meat intake and increasing plant-based food consumption are priorities for chronic disease prevention and environmental sustainability across Europe. Previous modelling has outlined how policy interventions could shift dietary patterns to align with meat reduction targets, but the resulting health impacts remain unexplored.</p><p><strong>Methods: </strong>We quantified the projected health impacts of the UK Climate Change Committee's (CCC) dietary targets-a 35% or 50% reduction in meat consumption-focusing on red and processed meat and substitution with vegetables and legumes, on incidence and mortality of key diet-related chronic diseases over 30 years. Dietary inputs were derived from an agent-based opinion dynamics model parameterised using the UK National Diet and Nutrition Survey data, and health impacts were estimated using the IOMLIFET life-table model.</p><p><strong>Results: </strong>Achieving the red and processed meat reduction components of the CCC's targets was associated with a projected increase in life expectancy of 7.2 (1.1-12.9) and 9.4 (1.3-15.4) months and years of life gained of 8.4 (1.3-14.9) and 10.9 (1.5-17.9) million, in the 35% and 50% scenarios, respectively. An estimated 3.4 (0.5-6.6) and 4.5 (0.6-8.1) million chronic disease cases could be averted. Up to 95% of health gains were attributable to cardiovascular outcomes, with three quarters linked to increased vegetable and legume consumption.</p><p><strong>Conclusion: </strong>These exploratory estimates suggest policy-driven reductions in red and processed meat aligned with climate goals could deliver substantial public health benefits. While conditional on modelled behavioural trajectories, findings offer relevant insights for European strategies to reduce cardiovascular disease burden and promote sustainable dietary transitions.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of 12 weeks of resistance and concurrent training with graded protein intakes on lipid profile, kidney and liver biomarkers in middle-aged to older women.","authors":"Reza Bagheri, Hamid Ghobadi, Mehdi Kargarfard, Katsuhiko Suzuki","doi":"10.1007/s00394-026-04096-3","DOIUrl":"10.1007/s00394-026-04096-3","url":null,"abstract":"<p><strong>Purpose: </strong>To examine secondary lipid, kidney-related, and liver-enzyme responses to three protein intakes during resistance training (RT) alone or the same RT plus cycling (CT) in middle-aged to older women.</p><p><strong>Methods: </strong>In this randomized 2×3 factorial trial, 108 women aged 40-77 years were assigned to RT or CT and 0.8, 1.6, or 2.2 g kg^-1 d^-1 protein for 12 weeks. This complete-case secondary analysis included 83 participants. Linear mixed-effects models tested Time × Training, Time × Protein, and Time × Training × Protein effects, with false-discovery-rate-adjusted omnibus tests and Holm-adjusted contrasts.</p><p><strong>Results: </strong>Triglycerides, total cholesterol, LDL-C, and apolipoprotein B decreased and HDL-C increased in all conditions. Lipid changes differed by protein condition, and several were more favorable with CT; however, CT comprised RT plus additional cycling and greater exercise exposure. Urea, blood urea nitrogen, creatinine, the blood urea nitrogen-to-creatinine ratio, and cystatin C increased, whereas three eGFR estimates decreased. Responses differed mainly between 0.8 and the two higher protein conditions, with little evidence of differences between 1.6 and 2.2 g kg^-1 d^-1. ALT, AST, and GGT differed by protein condition; AST and GGT also showed training-dependent responses.</p><p><strong>Conclusions: </strong>The dietary and exercise interventions modified lipid and clinical-chemistry responses. Because energy and food composition were not fully matched and CT added cycling to RT, the findings do not isolate protein dose or exercise modality. Changes in eGFR estimates and liver enzymes do not establish organ injury or long-term safety.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum metabolic signatures of nutritional status in early childhood: results from the Brazilian National Survey on Child Nutrition (ENANI-2019).","authors":"Samary da Silva Rosa Freire, Victor Nahuel Keller, Paula Normando, Raquel Machado Schincaglia, Nathalia Cristina Freitas-Costa, Inês Rugani Ribeiro de Castro, Zachary Kroezen, Meera Shanmuganathan, Philip Britz-McKibbin, Gilberto Kac","doi":"10.1007/s00394-026-04101-9","DOIUrl":"10.1007/s00394-026-04101-9","url":null,"abstract":"<p><strong>Background: </strong>Untargeted metabolic profiling may provide biochemical insights into adverse growth outcomes in early childhood. We aimed to investigate the association between serum metabolic signatures and anthropometric indicators in young children.</p><p><strong>Methods: </strong>The serum metabolome of 4978 children aged 6-59 months, studied by the 2019 Brazilian National Survey on Child Nutrition (ENANI-2019), was analyzed using multi-segment injection-capillary electrophoresis-mass spectrometry. WHO length/height-for-age (HAZ), weight-for-height (WHZ), body-mass-index-for-age (BMIZ), and weight-for-age (WAZ) indices, and stunting (HAZ <-2) and overweight (WHZ > 2) were the outcomes. Partial least squares regression was used to select serum metabolites with a variable importance projection ≥ 1. Linear and logistic regression models, adjusted for confounders and sex-stratified, were fitted. The Benjamini-Hochberg correction (adjusted p < 0.05) controlled the false discovery rate.</p><p><strong>Results: </strong>Tyrosine, creatinine, and 5-aminovaleric acid were consistently directly associated with all anthropometric indices. Threonine was directly associated with HAZ. The branched-chain amino acids were directly associated with WHZ. Leucine, valine, lysine, and carnitine were directly associated with BMIZ, whereas 3-hydroxybutyric acid was inversely associated with WAZ. Direct associations between methionine and WHZ, BMIZ, and WAZ, and between histidine and WHZ and BMIZ, were observed exclusively in girls, while hippuric acid and cresol sulfate were inversely associated with HAZ, and phenylacetylglutamine with WAZ, exclusively in boys. Further, 2-aminobutyric acid and creatinine were inversely associated with stunting, and proline betaine was inversely associated with being overweight.</p><p><strong>Conclusion: </strong>Serum metabolomics offers a valuable tool for screening for childhood malnutrition, and key metabolites were associated with energy and muscle metabolism, the endocrine system, and aspects of the human diet.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148954859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of three different dietary patterns with the metabolomic profiles of children: the BiomarKid project.","authors":"Irina Gheorghita, Lara Vehovec, Veit Grote, Jeannie Horak, Mariona Gispert-Llauradó, Natalia Ferré, Berthold Koletzko, Hans Demmelmair, Klaus Kratochwill, Elvira Verduci, Dariusz Gruszfeld, Joaquin Escribano, Gabi Kastenmüller, Veronica Luque","doi":"10.1007/s00394-026-04098-1","DOIUrl":"10.1007/s00394-026-04098-1","url":null,"abstract":"<p><strong>Background and aims: </strong>Metabolomics offers a promising approach to objectively assess food intake and nutrition-related health risks. Three different dietary patterns (DPs) associated with cardiometabolic health were previously identified at 2 years of age in the EU Childhood Obesity Project and were used as reference patterns for longitudinal scoring throughout childhood: \"Core foods\" DP (CORE), rich in vegetables, fruits, fish, meat, and olive oil; \"Animal protein sources\" DP (PROT), high in white meat, processed meat, flavoured milk, snacks, fish, and vegetables; and \"Poor-quality fats and sugars\" DP (F&S), high in soft cheese, butter, added sugars, and juices. This study aimed to identify metabolomic signatures of these DPs.</p><p><strong>Methods: </strong>Targeted liquid chromatography-tandem mass spectrometry quantified 236 metabolites in blood samples collected at ages 5.5 and 8 years from 421 children, with 156 children contributing samples at both timepoints. Associations between DPs and metabolite levels were assessed using adjusted linear mixed models. Metabolite set enrichment analysis (MSEA) was conducted across 23 distinct sets of related metabolites.</p><p><strong>Results: </strong>Forty-eight metabolites associated with DPs, although they did not remain significant after false discovery rate correction. Five showed associations with multiple DPs. For example, LPC a C22:6 showed associations with opposite effect directions for CORE and F&S (β = 0.108, p = 0.038, q = 0.539; β=- 0.140, p = 0.025, q = 0.484, respectively). The ratio PC aa C40:5/PC aa C40:6 was negatively associated with CORE (β=- 0.207, p = 3.81 × 10^- 5, q = 0.016) and positively with F&S (β = 0.136, p = 0.020, q = 0.463). CORE and F&S showed opposite directions in seven of the eight metabolite groups significant in the MSEA. A group of phosphatidylcholines containing polyunsaturated fatty acids (including DHA) was positively associated with PROT (NES: 1.837, p = 0.001, q = 0.017).</p><p><strong>Conclusions: </strong>Distinct metabolite groups were associated with adherence to specific dietary patterns in children. Consistent findings across metabolite classes and dietary components suggest biologically plausible metabolomic signatures that require confirmation in independent cohorts.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148955357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal digestion enhances the release of bioactive peptides from yogurt.","authors":"Christoper Caesar Yudho Sutopo, Wei-Ting Hung, Awang Tri Satria, Hariadi Darmawan, David Yudianto, Jue-Liang Hsu","doi":"10.1007/s00394-026-04095-4","DOIUrl":"10.1007/s00394-026-04095-4","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated whether simulated gastrointestinal (SGI) digestion enhances the release of bioactive peptides from yogurt and improves their associated bioactivities.</p><p><strong>Methods: </strong>Yogurt was subjected to INFOGEST-based SGI digestion. Bioactivities were evaluated using ACE and DPP-IV inhibition and DPPH radical scavenging assays. Protein degradation was assessed by SDS-PAGE, and peptides were identified by UPLC-LTQ Orbitrap mass spectrometry, followed by in silico peptide screening and molecular docking.</p><p><strong>Results: </strong>Compared with undigested yogurt, SGI digestion markedly enhanced ACE inhibitory, DPP-IV inhibitory, and antioxidant activities, with IC₅₀: 9.6 µg/mL, 300.3 µg/mL, and 530.7 µg/mL, respectively. SDS-PAGE confirmed extensive protein hydrolysis, accompanied by increased peptide content. Peptidomic analysis identified 129 oligopeptides, predominantly < 1.5 kDa, with 31 prioritized as predicted bioactive candidates. Selected peptides exhibited favorable predicted interactions with ACE, DPP-IV, Keap1, and DPPH.</p><p><strong>Conclusion: </strong>SGI digestion promotes the release of low-molecular-weight peptides with enhanced in vitro bioactivities, providing a peptide-level framework for prioritizing yogurt-derived peptide candidates for future validation. Further experimental validation is needed before functional food, nutraceutical, or therapeutic applications can be proposed.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148911243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of the maternal fish and PUFA intake with the risk of hypertensive disorders of pregnancy: a nationwide birth cohort-The Japan Environment and Children's Study (JECS).","authors":"Takuya Inouye, Daisuke Higeta, Kei Hamazaki, Akira Iwase, Akiko Tsuchida, Hidekuni Inadera, Eiji Yoshioka","doi":"10.1007/s00394-026-04103-7","DOIUrl":"10.1007/s00394-026-04103-7","url":null,"abstract":"<p><strong>Purpose: </strong>Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal and perinatal morbidity. Although n-3 polyunsaturated fatty acids (PUFAs) in fish may prevent HDP, evidence from Japanese populations, particularly regarding the preconception period, remains limited. To examine associations between fish and PUFA intake before and during pregnancy and the risk of HDP using data from a nationwide Japanese birth cohort.</p><p><strong>Methods: </strong>This analysis included 86,009 women from the Japan Environment and Children's Study. Dietary fish and n-3/n-6 PUFAs intake was assessed using a validated food-frequency questionnaire administered in early pregnancy (median gestational age, 15.0 weeks [interquartile range (IQR) 12.0-19.0]) to capture intake before pregnancy, and in mid to late pregnancy (median gestational age, 27.0 weeks [IQR 25.0-30.0]). Participants were categorized into quintiles of intake. Logistic regression models were used to estimate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for HDP, early-onset HDP (Eo-HDP < 32 weeks), and late-onset HDP (Lo-HDP ≥ 32 weeks). Missing data were addressed with multiple imputation.</p><p><strong>Results: </strong>In the overall population, higher fish intake before pregnancy was associated with reduced risks of Eo-HDP in the Q5 groups, whereas higher fish intake during pregnancy was associated with reduced risks of overall HDP in Q4. In analyses restricted to nulliparous women, higher pre-pregnancy fish intake was associated with a lower risk of Eo-HDP (Q4: aOR 0.57; 95% CI 0.34-0.97; p for trend = 0.02), and higher fish intake during pregnancy was associated with a lower risk of Lo-HDP (Q4: aOR 0.79; 95% CI 0.64-0.96). Total n-3 PUFA intake showed significant associations with HDP only in some analyses. Sensitivity analyses using a 34-week cutoff yielded consistent results.</p><p><strong>Conclusion: </strong>Fish intake before pregnancy was associated with lower risk of Eo-HDP, whereas intake during pregnancy was linked to reduced risk of Lo-HDP. Sustained fish consumption from preconception through pregnancy may help prevent HDP and inform global nutritional guidance, including preconception care.</p><p><strong>Trial registration: </strong>The Japan Environment and Children's Study, https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000035091 (Registration no. UMIN000030786).</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13553602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148911247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does higher food biodiversity in the Dutch diet lead to lower environmental impact?","authors":"Rosalie E Bakker, Rosa Leek, Reina E Vellinga, Corné van Dooren, Mary Nicolaou, Margreet R Olthof, Ingeborg A Brouwer","doi":"10.1007/s00394-026-04092-7","DOIUrl":"10.1007/s00394-026-04092-7","url":null,"abstract":"<p><strong>Purpose: </strong>Global diets exert substantial pressure on both public and planetary health. At the same time, diets are becoming more monotonous, with growing reliance on a limited number of staple species. Food biodiversity, the variety of biological species in the diet, and dietary environmental impact represent complementary, but distinct, dimensions of sustainable diets. However, because these dimensions capture different aspects of sustainability, it remains unclear whether diets with higher food biodiversity are also associated with lower environmental impacts.</p><p><strong>Methods: </strong>We examined associations between food biodiversity, measured as Dietary Species Richness (DSR), and six environmental impact indicators using data from the Dutch National Food Consumption Survey (DNFCS) 2012-2016. DSR scores (DSR Total, DSR Plant, DSR Animal) were calculated as the total unique species consumed over two 24-hour dietary recalls, regardless of quantities consumed. Environmental impacts associated with food consumption over the same recall period were derived from the Dutch life cycle assessment (LCA) food database (RIVM, v2019). Linear regression analyses were conducted, adjusting for age, sex, educational level, seasonality, mean daily energy intake, and weight of total food intake.</p><p><strong>Results: </strong>Higher DSR scores were generally associated with higher environmental impacts, including greenhouse gas emissions (β = 0.107, 95% CI 0.076 to 0.138), freshwater eutrophication (β = 1.28e-5, 95% CI 1.04e-5 to 1.51e-5), land use (β = 0.049, 95% CI 0.032 to 0.067), and blue water consumption (β = 0.014, 95% CI 0.012 to 0.015). Exploratory analyses adjusting for energy intake and total food intake attenuated most associations, while several associations remained statistically significant.</p><p><strong>Conclusion: </strong>Increasing DSR alone is unlikely to improve LCA-based environmental sustainability. Promoting diets that are both biodiverse and environmentally sustainable therefore requires consideration of both food biodiversity and the environmental characteristics of food production.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 7","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13541952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation and cultural adaptation of the pregnancy-adapted Mediterranean Diet Adherence Screener (ITpreg-MEDAS) in Italian pregnant women.","authors":"Silvia Callegaro, Francesca Scazzina, Pedro Mena, Christine Tita Kaihura, Andrea Dall'Asta, Ramon Estruch, Rosa Casas, Alice Rosi","doi":"10.1007/s00394-026-04087-4","DOIUrl":"10.1007/s00394-026-04087-4","url":null,"abstract":"<p><strong>Purpose: </strong>The beneficial effects of Mediterranean Diet (MD) during pregnancy are well established. However, validated tools adapted to assess adherence to the MD during pregnancy and across different cultural contexts remain limited. This study aimed to translate, cross-culturally adapt, and validate an Italian version of the pregnancy-adapted Mediterranean Diet Adherence Screener (ITpreg-MEDAS), derived from the original Spanish preg-MEDAS questionnaire. We hypothesized that the ITpreg-MEDAS would show adequate construct validity and would be associated with markers of diet quality during pregnancy.</p><p><strong>Methods: </strong>The preg-MEDAS is a 17-item questionnaire designed to assess adherence to the MD among pregnant women. The Italian version was developed following a six steps process in accordance with established methodological guidelines: forward translation, synthesis I, blind-back translation, synthesis II, pre-testing, and validation. Psychometric properties were evaluated by assessing internal consistency, test-retest reliability, and construct validity, in a sample of Italian pregnant women.</p><p><strong>Results: </strong>The preg-MEDAS was translated and cross-cultural adapted, requiring some semantic revisions. All 25 Italian pregnant women involved in the pre-testing in pre-testing found it clear and comprehensible. A total of 116 Italian pregnant women participated in the validation phase, with a mean ITpreg-MEDAS score of 7.2 ± 2.5 out of 17, indicating medium adherence to the MD. Reliability was confirmed by good test-retest correlation (r = 0.756) and acceptable internal consistency (Cronbach's α = 0.623).</p><p><strong>Conclusion: </strong>The ITpreg-MEDAS is a reliable and valid Italian version of the preg-MEDAS questionnaire, providing a simple tool to assess adherence to the Mediterranean Diet during pregnancy in both clinical practice and research.</p>","PeriodicalId":12030,"journal":{"name":"European Journal of Nutrition","volume":"65 6","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13526079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}