Inga Voges, Francesca Raimondi, Colin J McMahon, Lamia Ait-Ali, Sonya V Babu-Narayan, René M Botnar, Barbara Burkhardt, Dominik D Gabbert, Lars Grosse-Wortmann, Hosan Hasan, Georg Hansmann, Willem A Helbing, Sylvia Krupickova, Heiner Latus, Nicola Martini, Duarte Martins, Vivek Muthurangu, Tiina Ojala, Pim van Ooij, Kuberan Pushparajah, Jose Rodriguez-Palomares, Samir Sarikouch, Heynric B Grotenhuis, F Gerald Greil, Yohann Bohbot, Maja Cikes, Marc Dweck, Erwan Donal, Julia Grapsa, Niall Keenan, Aniela Monica Petrescu, Liliana Szabo, Fabrizio Ricci, Valtteri Uusitalo
{"title":"Clinical impact of novel cardiovascular magnetic resonance technology on patients with congenital heart disease: a scientific statement of the Association for European Pediatric and Congenital Cardiology and the European Association of Cardiovascular Imaging of the European Society of Cardiology.","authors":"Inga Voges, Francesca Raimondi, Colin J McMahon, Lamia Ait-Ali, Sonya V Babu-Narayan, René M Botnar, Barbara Burkhardt, Dominik D Gabbert, Lars Grosse-Wortmann, Hosan Hasan, Georg Hansmann, Willem A Helbing, Sylvia Krupickova, Heiner Latus, Nicola Martini, Duarte Martins, Vivek Muthurangu, Tiina Ojala, Pim van Ooij, Kuberan Pushparajah, Jose Rodriguez-Palomares, Samir Sarikouch, Heynric B Grotenhuis, F Gerald Greil, Yohann Bohbot, Maja Cikes, Marc Dweck, Erwan Donal, Julia Grapsa, Niall Keenan, Aniela Monica Petrescu, Liliana Szabo, Fabrizio Ricci, Valtteri Uusitalo","doi":"10.1093/ehjci/jeae172","DOIUrl":"10.1093/ehjci/jeae172","url":null,"abstract":"<p><p>Cardiovascular magnetic resonance (CMR) imaging is recommended in patients with congenital heart disease (CHD) in clinical practice guidelines as the imaging standard for a large variety of diseases. As CMR is evolving, novel techniques are becoming available. Some of them are already used clinically, whereas others still need further evaluation. In this statement, the authors give an overview of relevant new CMR techniques for the assessment of CHD. Studies with reference values for these new techniques are listed in the Supplementary data online, supplement.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"e274-e294"},"PeriodicalIF":6.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eva Swahn, Sofia Sederholm Lawesson, Joakim Alfredsson, Mats Fredrikson, Oskar Angerås, Olov Duvernoy, Gunnar Engström, Maria J Eriksson, Erika Fagman, Bengt Johansson, Linda Johnson, Nina Johnston, Johan Ljungberg, Maria Mannila, Maria Nordendahl, Jonas Oldgren, Elmir Omerovic, Ellen Ostenfeld, Margaretha Persson, Annika Rosengren, Linn Skoglund Larsson, Johan Sundström, Mia Söderberg, Carl Johan Östgren, Karin Leander, Tomas Jernberg
{"title":"Sex differences in prevalence and characteristics of imaging-detected atherosclerosis: a population-based study.","authors":"Eva Swahn, Sofia Sederholm Lawesson, Joakim Alfredsson, Mats Fredrikson, Oskar Angerås, Olov Duvernoy, Gunnar Engström, Maria J Eriksson, Erika Fagman, Bengt Johansson, Linda Johnson, Nina Johnston, Johan Ljungberg, Maria Mannila, Maria Nordendahl, Jonas Oldgren, Elmir Omerovic, Ellen Ostenfeld, Margaretha Persson, Annika Rosengren, Linn Skoglund Larsson, Johan Sundström, Mia Söderberg, Carl Johan Östgren, Karin Leander, Tomas Jernberg","doi":"10.1093/ehjci/jeae217","DOIUrl":"10.1093/ehjci/jeae217","url":null,"abstract":"<p><strong>Aims: </strong>Men are more likely to suffer a myocardial infarction than women, but population-based studies on sex differences in imaging-detected atherosclerosis are lacking. The aims were to assess sex differences in the prevalence of imaging-detected coronary and carotid atherosclerosis, as well as multivariable adjusted associations between sex and atherosclerosis.</p><p><strong>Methods and results: </strong>Participants aged 50-65, recruited from the general population to the Swedish Cardiopulmonary bioImage Study (SCAPIS), were included in this population-based cross-sectional study. Comprehensive diagnostics, including coronary computed tomography angiography and carotid ultrasound, were performed. The image findings were any coronary atherosclerosis, coronary stenosis ≥ 50%, segment involvement score (SIS) ≥ 4, coronary artery calcium score (CACS) > 100, and any ultrasound-detected carotid plaque. In 25 580 participants (50% women), men had more hypertension (20.3% vs. 17.0%), hyperlipidaemia (9.0% vs. 5.5%), and diabetes (8.5% vs. 4.7%). The prevalence was 56.2% vs. 29.5% for any coronary atherosclerosis (P < 0.01), 9.0% vs. 2.3% for coronary stenosis ≥ 50% (P < 0.01), 20.2% vs. 5.3% for SIS ≥ 4 (P < 0.01), 18.2% vs. 5.6% for CACS > 100 (P < 0.01), and 60.9% vs. 48.7% for carotid plaque (P < 0.01), in men vs. women, respectively. Multivariable adjustment only marginally changed these associations: odds ratios (ORs) (95% confidence interval): 2.75 (2.53-2.99) for coronary atherosclerosis, 2.88 (2.40-3.45) for coronary stenosis ≥ 50%, 3.99 (3.50-4.55) for SIS ≥ 4, 3.29 (2.88-3.75) for CACS > 100, and 1.57 (1.45-1.70) for carotid plaque.</p><p><strong>Conclusion: </strong>Men had higher prevalence of imaging-detected carotid and coronary atherosclerosis with prevalence in women aged 65 corresponding to men 11-13 years younger. The associations remained after extensive multivariable adjustment.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1663-1672"},"PeriodicalIF":6.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riccardo M Inciardi, Wendy Wang, Alvaro Alonso, Elsayed Z Soliman, Senthil Selvaraj, Alexandra Gonçalves, Michael J Zhang, Alvin Chandra, Narayana G Prasad, Hicham Skali, Amil M Shah, Scott D Solomon, Lin Yee Chen
{"title":"Cardiac mechanics and the risk of atrial fibrillation in a community-based cohort of older adults.","authors":"Riccardo M Inciardi, Wendy Wang, Alvaro Alonso, Elsayed Z Soliman, Senthil Selvaraj, Alexandra Gonçalves, Michael J Zhang, Alvin Chandra, Narayana G Prasad, Hicham Skali, Amil M Shah, Scott D Solomon, Lin Yee Chen","doi":"10.1093/ehjci/jeae162","DOIUrl":"10.1093/ehjci/jeae162","url":null,"abstract":"<p><strong>Aims: </strong>Assessment of cardiac structure and function improves risk prediction of new-onset atrial fibrillation (AF) in different populations. We aimed to comprehensively compare standard and newer measures of cardiac structure and function in improving prediction of AF in a cohort of older adults without history of AF and stroke.</p><p><strong>Methods and results: </strong>We included 5050 participants without prevalent AF and stroke (mean age 75 ± 5 years, 59% women, and 22% Black) from the Atherosclerosis Risk in Communities (ARIC) study who underwent complete two-dimensional echocardiography, including speckle-tracking analysis of the left ventricle (LV) and left atrium (LA). We assessed the association of cardiac measures with incident AF (including atrial flutter) and quantified the extent to which these measures improved model discrimination and risk classification of AF compared with the CHARGE-AF score. Over a median follow-up time of 7 years, 676 participants developed AF (incidence rate 2.13 per 100 person-years). LV mass index and wall thickness, E/e', and measures of LA structure and function, but not LV systolic function, were associated with incident AF, after accounting for confounders. Above all, LA reservoir strain, contraction strain, and LA minimal volume index (C-statistics [95% confidence interval]: 0.73 [0.70, 0.75], 0.72 [0.70, 0.75], and 0.72 [0.69, 0.75], respectively) significantly improved the risk discrimination of the CHARGE-AF score (baseline C-statistic: 0.68 [0.65, 0.70]) and achieved the highest category-based net reclassification improvement (29%, 24%, and 20%, respectively).</p><p><strong>Conclusion: </strong>In a large cohort of older adults without prevalent AF and stroke, measures of LA function improved the prediction of AF more than other conventional cardiac measures.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1686-1694"},"PeriodicalIF":6.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141497514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alan C Kwan, Naga Dharmavaram, Orit Barrett, Daniel S Berman, Evan P Kransdorf
{"title":"Patterns of late gadolinium enhancement in MYBPC3-related dilated cardiomyopathy: imitating the imitator.","authors":"Alan C Kwan, Naga Dharmavaram, Orit Barrett, Daniel S Berman, Evan P Kransdorf","doi":"10.1093/ehjci/jeae230","DOIUrl":"10.1093/ehjci/jeae230","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"e332"},"PeriodicalIF":6.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eugenio Picano, Eliseo Vano, Robert P Gale, Patrick Serruys
{"title":"Cardiac radiation exposure and incident cancer: challenges and opportunities.","authors":"Eugenio Picano, Eliseo Vano, Robert P Gale, Patrick Serruys","doi":"10.1093/ehjci/jeae257","DOIUrl":"10.1093/ehjci/jeae257","url":null,"abstract":"<p><p>The use of radiological procedures has enormously advanced cardiology. People with heart disease are exposed to ionizing radiation. Exposure to ionizing radiation increases lifetime cancer risk with a dose-proportional hazard according to the linear no-threshold model adopted for radioprotection purposes. In the USA, the average citizen accumulates a median annual medical radiation exposure of 2.29 millisievert per year per capita as of the radiologic year 2016, corresponding to the dose exposure of 115 chest X-rays. Cardiology studies often involve high exposures per procedure accounting for ∼30-50% of cumulative medical radiation exposures. Malignancy is more incident in the most radiosensitive organs receiving the largest organ dose from cardiac interventions and cardiovascular imaging testing, such as the lung, bone marrow, and female breast. The latency period between radiation exposure and cancer is thought to be at least 2 years for leukaemia and 5 years for all solid cancers, and differences are more likely to emerge in cardiology studies with longer follow-up and inclusion of non-cardiovascular endpoints such as cancer incidence. In cardiological studies, excess cancers are observed 3-12 years following exposure, with longer follow-up times showing greater differences in cancer incidence. The presumed associated excess cancer risk needs greater study. These exposures provide a unique opportunity to expand our knowledge of the relationship between exposure to ionizing radiation and cancer risk. Future trials comparing interventional fluoroscopy vs. optimal medical therapy or open surgery should include a cancer incidence endpoint.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1620-1626"},"PeriodicalIF":6.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mara Gavazzoni, Luigi P Badano, Giordano Maria Pugliesi, Marco Penso, Diana-Ruxandra Hădăreanu, Pellegrino Ciampi, Samantha Fisicaro, Giorgio Oliverio, Francesca Heilbron, Michele Tomaselli, Denisa Muraru
{"title":"Assessing right atrial size in patients with tricuspid regurgitation: importance of the right ventricular-focused view.","authors":"Mara Gavazzoni, Luigi P Badano, Giordano Maria Pugliesi, Marco Penso, Diana-Ruxandra Hădăreanu, Pellegrino Ciampi, Samantha Fisicaro, Giorgio Oliverio, Francesca Heilbron, Michele Tomaselli, Denisa Muraru","doi":"10.1093/ehjci/jeae186","DOIUrl":"10.1093/ehjci/jeae186","url":null,"abstract":"<p><strong>Aims: </strong>To assess the accuracy of measuring the right atrial volume (RAV) using two-dimensional echocardiography (2DE) in a right ventricular focused (RVF) view compared to the conventional apical four-chamber (4Ch) view in patients with secondary tricuspid regurgitation (STR). We also compared the clinical correlates of the measures obtained using different methods.</p><p><strong>Methods and results: </strong>The accuracy of RAV measurements obtained between 2DE-4Ch and RVF views in 384 patients with STR were compared using three-dimensional echocardiography (3DE) as a reference. We used the analysis of variance to test the differences among RAVs obtained from the different 2DE and 3DE acquisitions and the receiving operating characteristics (ROC) curves to evaluate the association with the composite endpoint of hospitalization for heart failure or death. Compared to 3DE, RAV was significantly more underestimated when measurements were obtained from 4Ch rather than RVF (-24 vs. -14%, respectively, P < 0.001 for both). RAV underestimation in 4Ch and RVF view was relatively larger in lower grades of STR (-28 vs. -17% in mild, -23 vs. -14% in moderate, and -19 vs. -11% in severe STR, P = 0.001), and in the atrial compared to ventricular (-28 vs. -22%; P = 0.002) STR. RAV measured by 3DE and RVF showed the highest area under the curve (AUC = 0.67 for 3DE vs. 0.64 for RVF, P = 0.05), while 4Ch was significantly less related to the outcomes (AUC: 0.61, P = 0.021 vs. 3DE RAV).</p><p><strong>Conclusion: </strong>In patients with STR, the use of RVF view improved the accuracy of 2DE RAV measurement as compared to the conventional 4Ch-derived measurements.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1743-1750"},"PeriodicalIF":6.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander C Egbe, William R Miranda, C Charles Jain, Luke J Burchill, Kathleen A Young, Carl H Rose, Snigdha Karnakoti, Marwan H Ahmed, Heidi M Connolly
{"title":"Cardiac remodelling during pregnancy in women with congenital heart disease and systemic left ventricle.","authors":"Alexander C Egbe, William R Miranda, C Charles Jain, Luke J Burchill, Kathleen A Young, Carl H Rose, Snigdha Karnakoti, Marwan H Ahmed, Heidi M Connolly","doi":"10.1093/ehjci/jeae173","DOIUrl":"10.1093/ehjci/jeae173","url":null,"abstract":"<p><strong>Aims: </strong>Women with congenital heart disease (CHD) are at risk of pregnancy-related adverse outcomes (PRAO). The purpose of this study was to assess temporal changes in cardiac structure and function (cardiac remodelling) during pregnancy, and the association with PRAO in women with CHD.</p><p><strong>Methods and results: </strong>Retrospective study of pregnant women with CHD and serial echocardiograms (2003-2021). Cardiac structure and function were assessed at pre-specified time points: prepregnancy, early pregnancy, late pregnancy, and postnatal period. PRAO was defined as the composite of maternal cardiovascular, obstetric, and neonatal complications. The study comprised 81 women with CHD (age, 29 ± 5 years). Compared to the baseline echocardiogram, there was a relative increase in right ventricular systolic pressure (RVSP) (relative change 13 ± 5%, P < 0.001, in early pregnancy; and 18 ± 5%, P < 0.001, in late pregnancy). There was a relative decrease in right ventricle free wall strain (RVFWS) (relative change -11 ± 3%, P < 0.001, in late pregnancy; and -11 ± 4%, P = 0.003, in postnatal period), and a relative decrease in RVFWS/RVSP (relative change, -10 ± 5%, P = 0.02 in early pregnancy, -26 ± 7%, P < 0.001, in late pregnancy, and -14 ± 5%, P < 0.001, in postnatal period). Baseline right ventricular to pulmonary arterial (RV-PA) coupling, and temporal change in RV-PA coupling were associated with PRAO, after adjustment for maternal age and severity of cardiovascular disease.</p><p><strong>Conclusion: </strong>Women with CHD had a temporal decrease in RV systolic function and RV-PA coupling, and these changes were associated with PRAO. Further studies are required to delineate the aetiology of deterioration in RV-PA coupling during pregnancy, and the long-term implications of right heart dysfunction observed in the postnatal period.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1695-1702"},"PeriodicalIF":6.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11601722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}