{"title":"Response to \"Clinical Transition from Prognosis to Decision-Making: Integrating Myocardial Mass at Risk with Tissue Characterization by Cardiac CT\".","authors":"Tetsuya Oguni, Yasuhiro Izumiya, Kenichi Tsujita","doi":"10.1093/ehjci/jeag116","DOIUrl":"https://doi.org/10.1093/ehjci/jeag116","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Transition from Prognosis to Decision-Making: Integrating Myocardial Mass at Risk with Tissue Characterization by Cardiac CT.","authors":"Kenji Sadamatsu, Yoshihiro Fukumoto","doi":"10.1093/ehjci/jeag115","DOIUrl":"https://doi.org/10.1093/ehjci/jeag115","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147835529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The co-occurrence of sepsis and left coronary artery-right ventricular fistula with a giant coronary aneurysm: contrast echocardiography and transcatheter closure.","authors":"Chunting Liang, Decai Zeng, Jie Shen","doi":"10.1093/ehjci/jeag118","DOIUrl":"https://doi.org/10.1093/ehjci/jeag118","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vasileios Kamperidis, Vasileios Anastasiou, George Giannakoulas
{"title":"Right ventricular global wasted work in pulmonary arterial hypertension by 2D echocardiography predicts high mortality risk using a spline curve-derived cut-off.","authors":"Vasileios Kamperidis, Vasileios Anastasiou, George Giannakoulas","doi":"10.1093/ehjci/jeag030","DOIUrl":"https://doi.org/10.1093/ehjci/jeag030","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":"27 5","pages":"1148-1149"},"PeriodicalIF":6.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sagit Ben Zekry, Georgios Tzimas, Jonathon Leipsic, Samuel Broderick, G B John Mancini, Cameron J Hague, Matthew J Budoff, James K Min, Bernard R Chaitman, Frank W Rockhold, Derek Cyr, Leslee J Shaw, Daniel S Berman, Michael H Picard, Daniel B Mark, Jerome L Fleg, Kian Keong Poh, Ziad A Ali, Gregg W Stone, Sean M O'Brien, Judith S Hochman, David J Maron, Harmony R Reynolds
{"title":"Additive prognostic value of functional performance to coronary artery anatomy: the ISCHEMIA trial.","authors":"Sagit Ben Zekry, Georgios Tzimas, Jonathon Leipsic, Samuel Broderick, G B John Mancini, Cameron J Hague, Matthew J Budoff, James K Min, Bernard R Chaitman, Frank W Rockhold, Derek Cyr, Leslee J Shaw, Daniel S Berman, Michael H Picard, Daniel B Mark, Jerome L Fleg, Kian Keong Poh, Ziad A Ali, Gregg W Stone, Sean M O'Brien, Judith S Hochman, David J Maron, Harmony R Reynolds","doi":"10.1093/ehjci/jeag032","DOIUrl":"10.1093/ehjci/jeag032","url":null,"abstract":"<p><strong>Aims: </strong>To assess whether baseline functional performance assessed by exercise treadmill stress testing (EST) has additive value to coronary computed tomography angiography (CCTA) for risk stratification among patients with chronic coronary disease (CCD) and moderate or severe ischaemia.</p><p><strong>Methods and results: </strong>We performed a subgroup analysis of the ISCHEMIA trial including participants who underwent EST and CCTA. EST data and severity of coronary artery disease (CAD) on CCTA were evaluated by core laboratories, blinded to clinical data and results of the other tests. The primary outcome for this analysis was all-cause death. Secondary outcomes were cardiovascular death, cardiovascular death or myocardial infarction (MI), MI and a composite of cardiovascular death, MI, or hospitalization for heart failure, unstable angina, or resuscitated cardiac arrest. EST and the number of vessels diseased on CCTA were both interpretable in 1864 patients (median age 62 years, IQR 55-68, 83% males). During a median follow-up of 3.1 years, 69 patients died. Higher peak metabolic equivalents (METs) achieved on the qualifying stress test was associated with lower all-cause death (HR 0.86, 95% CI 0.76-0.98; P = 0.025). The addition of peak METs to CAD severity improved the predictive ability of the all-cause death and CV death models by 10-20% and 8-13% respectively, depending on the metrics used for CCTA. Adding peak METs to CCTA anatomical models resulted in better prediction of MI by 11-17%, cardiovascular death or MI by 10-14%, and 5-component composite outcome by 12-16%.</p><p><strong>Conclusion: </strong>Peak METs on EST, a marker of functional performance, added prognostic value to models including CCTA anatomical findings in patients with CCD and moderate or severe ischaemia.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"952-966"},"PeriodicalIF":6.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13014304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146118259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Clement, Denisa Muraru, Marco Penso, Michele Tomaselli, Noela Radu, Alexandra S Buta, Samantha Fisicaro, Valeria Rella, Paolo Springhetti, Yuka Kawada, Giorgia Benzoni, Cristian Statescu, Radu Sascau, Luigi P Badano
{"title":"Association of right atrioventricular coupling and right atrial stiffness indices with outcomes in secondary tricuspid regurgitation patients.","authors":"Alexandra Clement, Denisa Muraru, Marco Penso, Michele Tomaselli, Noela Radu, Alexandra S Buta, Samantha Fisicaro, Valeria Rella, Paolo Springhetti, Yuka Kawada, Giorgia Benzoni, Cristian Statescu, Radu Sascau, Luigi P Badano","doi":"10.1093/ehjci/jeag062","DOIUrl":"10.1093/ehjci/jeag062","url":null,"abstract":"<p><strong>Aims: </strong>In secondary tricuspid regurgitation (STR) patients, the clinical value of right atrioventricular coupling (RAVC) and right atrial (RA) stiffness indices has never been evaluated. Accordingly, we explored the association with a composite outcome of all-cause mortality or heart failure hospitalization of (i) RAVC index obtained either with speckle tracking echocardiography (RAVCSTE) or as the ratio between RA volume (RAV) and right ventricular (RV) stroke volume (RAVCVOL) and (ii) RA stiffness index calculated as the ratio between RAV index and RA longitudinal reservoir strain (RALS).</p><p><strong>Methods and results: </strong>513 patients with mild-to-severe STR (75 ± 13 years, 58% severe) were included. After a mean follow-up of 18 ± 15 months, 195 patients (38%) reached the composite endpoint. On spline curve modelling, the cut-off values associated with increased 2-year event rates were (i) < 0.82 for RAVCSTE (reduced values of the ratio between RALS and RV free wall strain indicating impaired coupling, the RA not supporting effectively the RV filling, despite a good systolic function of the RV); (ii) > 1.23 for RAVCVOL (higher values suggesting greater RA remodelling relative to RV stroke volume and altered coupling); (iii) > 4.6 for RA stiffness index (higher values indicating a diminished RA compliance to filling). However, in multivariable Cox regression analyses and hierarchical χ2 analyses, only RAVCVOL maintained a significant association with the outcome (P < 0.05).</p><p><strong>Conclusion: </strong>In STR patients, RAVC and RA stiffness indices are associated with the risk of events, with RAVCVOL yielding the strongest association.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1082-1095"},"PeriodicalIF":6.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soraya Tadimi-Tazi, Patricia Muñoz, Marina Machado-Vilchez, Antonia Delgado-Montero, Maria Carmen Fariñas-Álvarez, Manuel Cobo-Belaustegui, Bàrbara Vidal-Hagemeijer, Maria Ángeles Rodríguez-Esteban, Juan Carlos Lopez-Azor, Miguel Ángel Goenaga-Sánchez, José Antonio Oteo, Juan Carlos Gainzarain-Arana, Manuel Martínez-Sellés
{"title":"Prognostic impact of vegetation size in infective endocarditis.","authors":"Soraya Tadimi-Tazi, Patricia Muñoz, Marina Machado-Vilchez, Antonia Delgado-Montero, Maria Carmen Fariñas-Álvarez, Manuel Cobo-Belaustegui, Bàrbara Vidal-Hagemeijer, Maria Ángeles Rodríguez-Esteban, Juan Carlos Lopez-Azor, Miguel Ángel Goenaga-Sánchez, José Antonio Oteo, Juan Carlos Gainzarain-Arana, Manuel Martínez-Sellés","doi":"10.1093/ehjci/jeag061","DOIUrl":"10.1093/ehjci/jeag061","url":null,"abstract":"<p><strong>Aims: </strong>The prognostic impact of vegetation size in infective endocarditis (IE) remains unclear. Our aim was to evaluate the relation between vegetation size and outcome.</p><p><strong>Methods and results: </strong>Our data come from the Spanish IE registry between 2008 and 2024. From 6525 IE patients, 5000 (76.6%) had vegetations and 3592 (55.1%) had documented vegetation size measurements. Patients were categorized into two groups based on maximum vegetation diameter: <10 mm (1319-36.7%) and ≥10 mm (2273-63.3%). Compared to patients with small vegetations, patients with vegetations ≥10 mm were younger (68 vs. 70 years, P < 0.001), had more frequent right-sided IE (8.0% vs. 4.1%, P < 0.001), less prosthetic valve IE (23.9% vs. 29.9%, P < 0.001), higher surgical rates (55.9% vs. 40.1%, P < 0.001), more embolic events (28.0% vs. 21.4%, P < 0.001), and higher in-hospital mortality (28.3% vs. 19.6%, P < 0.001) and 1-year mortality (35.6% vs. 27.5%, P < 0.001). Large vegetation size was an independent predictor of in-hospital mortality (odds ratio [OR] 1.6, 95% confidence interval [CI] 1.3-1.9, P < 0.001), embolic events (OR 1.34, 95% CI 1.15-1.55, P < 0.001), and 1-year mortality (hazard ratio 1.32, 95% CI 1.17-1.50, P < 0.001). Vegetation size was an independent predictor of in-hospital mortality in left-sided IE (OR 1.7, 95% CI 1.4-2.1, P < 0.001) but not in right-sided IE (OR 1.2, 95% CI 0.7-2.3, P = 0.50).</p><p><strong>Conclusion: </strong>In patients with IE, large vegetation size is independently associated with embolic events and increased mortality particularly in those with left-sided IE, suggesting the need for more aggressive management in these patients.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1070-1079"},"PeriodicalIF":6.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}