Ivan Lechner, Jaclyn Carberry, Thomas Stiermaier, Christina Tiller, Magdalena Holzknecht, Fritz Oberhollenzer, Alex Kaser, Johannes Mair, Agnes Mayr, Hans-Josef Feistritzer, David Carrick, Clemens Dlaska, Axel Bauer, Holger Thiele, Ingo Eitel, Bernhard Metzler, Colin Berry, Martin Reindl, Sebastian J Reinstadler
{"title":"Associations and Prognostic Implications of Myocardial Tissue Injury Stages in ST-Elevation Myocardial Infarction Using the Canadian Cardiovascular Society Classification.","authors":"Ivan Lechner, Jaclyn Carberry, Thomas Stiermaier, Christina Tiller, Magdalena Holzknecht, Fritz Oberhollenzer, Alex Kaser, Johannes Mair, Agnes Mayr, Hans-Josef Feistritzer, David Carrick, Clemens Dlaska, Axel Bauer, Holger Thiele, Ingo Eitel, Bernhard Metzler, Colin Berry, Martin Reindl, Sebastian J Reinstadler","doi":"10.1093/ehjci/jeaf250","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf250","url":null,"abstract":"<p><strong>Aims: </strong>The recently proposed Canadian Cardiovascular Society (CCS) classification categorizes post-infarction tissue injury into four stages, potentially improving risk stratification and guiding cardioprotective strategies. Its clinical and prognostic relevance in ST-elevation myocardial infarction (STEMI) remains unclear. We aimed to compare clinical characteristics across CCS stages and validate their prognostic implications in STEMI.</p><p><strong>Methods and results: </strong>We analysed 1,109 STEMI patients included in three prospective studies. Cardiac magnetic resonance (CMR) imaging was performed 3 (interquartile range 2-5) days after MI and patients were classified as follows: stage 1 (aborted MI), stage 2 (MI with necrosis and absence of microvascular injury), stage 3 (MI with necrosis and microvascular obstruction) and stage 4 (MI with necrosis and intramyocardial haemorrhage).This analysis revealed distinct patterns of clinical presentation, biomarker profiles and cardiac function at different CCS stages. There were differences in adverse clinical event rates and mortality between CCS stages (major adverse cardiovascular event [MACE]: 0.7%, 3.4%, 3.1%, 15.7%, p<0.001 and mortality: 0.7%, 1.7%, 0.9%, 6.3%, p<0.001). The CCS stage had a moderate to good predictive value for MACE and mortality (AUC 0.74 [95% CI: 0.68-0.80], p<0.001 and AUC 0.71 [95% CI: 0.61-0.80], p<0.001) at 12 months, respectively. CCS stages were independently associated with MACE in multivariable Cox regression (HR: 2.18 [95% CI, 1.70-2.78], p<0.001).</p><p><strong>Conclusion: </strong>This study describes clinical characteristics across CCS stages and provides insights into their prognostic implications in a large cohort of STEMI patients reperfused by PCI. These data should inform the use of CCS stages in future trial designs.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hatem Soliman Aboumarie, Guido Tavazzi, Gabriele Via, Fabio Guarracino, Ivan Stankovic, Andreas Hagendorff, Luna Gargani, Nuno Cardim, Frank A Flachskampf, Jeroen Bax, Chirojit Mukherjee, Massimiliano Meineri, Stefaan Bouchez, Johan Bence, Henry Skinner, Bernard Cosyns, Susanna Price, Aleksandar N Neskovic
{"title":"Cardiac Ultrasound in Cardiovascular Emergency and Critical Care. A Clinical Consensus Statement of the European Association of Cardiovascular Imaging (EACVI), the Acute CardioVascular Care Association (ACVC) of the ESC, and the European Association of Cardiothoracic Anaesthesia and Intensive Care (EACTAIC).","authors":"Hatem Soliman Aboumarie, Guido Tavazzi, Gabriele Via, Fabio Guarracino, Ivan Stankovic, Andreas Hagendorff, Luna Gargani, Nuno Cardim, Frank A Flachskampf, Jeroen Bax, Chirojit Mukherjee, Massimiliano Meineri, Stefaan Bouchez, Johan Bence, Henry Skinner, Bernard Cosyns, Susanna Price, Aleksandar N Neskovic","doi":"10.1093/ehjci/jeaf246","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf246","url":null,"abstract":"<p><p>Cardiac ultrasound (CUS) has emerged as an indispensable bedside diagnostic and monitoring tool in cardiovascular emergencies and critical care, enabling rapid, noninvasive assessment of cardiac structure and function. This multidisciplinary consensus statement, jointly developed by the EACVI, ACVC, and EACTAIC, provides comprehensive, practical guidance on the use of CUS in acute care settings. The document outlines a pathophysiological framework for applying CUS across a wide spectrum of clinical scenarios, including cardiogenic shock, acute myocardial infarction, mechanical complications, acute heart failure, severe valvular disease, pericardial tamponade, pulmonary embolism, and cardiac arrest. It describes key ultrasound modalities, measurement techniques, and diagnostic considerations essential for accurate interpretation and decision-making. Emphasis is placed on integrating CUS with multimodal imaging and organ-specific ultrasound to improve diagnostic accuracy and risk stratification. The consensus further defines recommended training pathways, competence levels, and governance standards to ensure high-quality practice and mitigate medicolegal risks. Looking ahead, the document highlights future perspectives, including the transformative potential of artificial intelligence, big data, and connected technologies to enhance CUS capabilities. By standardising approaches and promoting interdisciplinary collaboration, this statement aims to optimise patient outcomes and advance the role of cardiac ultrasound as a cornerstone of emergency and critical cardiovascular care.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mayari A Gulati, Kimberly A Holst, Tyler J Peterson, Juan A Crestanello, Sorin V Pislaru
{"title":"Double Jeopardy: Not All Dysfunctional Mechanical Mitral Valves Are Thrombosed.","authors":"Mayari A Gulati, Kimberly A Holst, Tyler J Peterson, Juan A Crestanello, Sorin V Pislaru","doi":"10.1093/ehjci/jeaf241","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf241","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilizing Multimodal Imaging for the Diagnosis of a Rare Calcifying Fibrous Tumor in the Right Ventricular.","authors":"Shiying Li, Lin He, Zhen Wang, Yali Yang","doi":"10.1093/ehjci/jeaf243","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf243","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidental myocardial haemangioma in an asymptomatic young woman: the central role of cardiac magnetic resonance imaging as a key diagnostic tool.","authors":"Nicola Gonano, Mariangela Murgante, Francesca Marchetti, Gianluca Pontone","doi":"10.1093/ehjci/jeaf239","DOIUrl":"10.1093/ehjci/jeaf239","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term adiposity in early adulthood affects coronary artery calcification incidence in midlife: a 25-year longitudinal study.","authors":"Shunyi Li, Haobin Zhou, Wenyan Li, Liusheng Wang, Qiming Zhao, Jun Chen, Song Lin, Shichao Li, Sijie Jiang, Weijing Feng, Qianqin Li, Dingli Xu, Qingchun Zeng","doi":"10.1093/ehjci/jeaf236","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf236","url":null,"abstract":"<p><strong>Aims: </strong>The study aimed to evaluate longitudinal adiposity exposure, assessed by body roundness index (BRI), from young adulthood and its association with the risk of coronary artery calcification (CAC) incidence in midlife.</p><p><strong>Methods: </strong>We included 2102 participants from the CARDIA study with available BRI measurements at eight follow-up visits over 25 years. Cardiac computed tomography at year 25 exam was used to assess the presence of CAC (CAC > 0). The cumulative BRI (cBRI) was calculated as the mean of BRI between consecutive visits multiplied by the number of years. Logistic regression models and restricted cubic spline (RCS) analyses were assessed the relationship between cBRI and the risk of CAC incidence.</p><p><strong>Results: </strong>A total of 598 participants developed CAC, over the 25-year follow-up period. Higher cBRI was associated with an increased risk of CAC incidence. Participants were divided into four quartiles based on cBRI. In model 3, the odds ratio (OR) for CAC was 2.52(95%CI, 1.82 - 3.49) in the top quartile of cBRI. RCS analyses suggested linear-shaped relationship between cBRI and the risk of CAC incidence. Furthermore, multivariable Cox regression showed that individuals in the higher cBRI had a higher risk of all-cause mortality (1.009; 95% CI, 1.003-1.016).</p><p><strong>Conclusions: </strong>Greater cBRI from early adulthood was associated with an elevated risk of CAC incidence in mid-life. These findings uncover potential evidence to support that BRI may be a useful marker for identifying individuals at high risk of CAC.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preventive Treatment of Thin-Cap Fibroatheroma in Patients with Diabetes Mellitus: Mind the Gap!","authors":"Fernando Alfonso, David Del Val, Elvin Kedhi","doi":"10.1093/ehjci/jeaf240","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf240","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W Javed, R Tomoaia, M Farooq, B Chambers, I Botis, Z Goh, B Brown, L A Brown, J Farley, H Xue, E Levelt, E Dall'Armellina, J P Greenwood, P Kellman, S Plein, P P Swoboda
{"title":"Cardiovascular magnetic resonance to differentiate veteran athlete's heart with cavity dilatation and mild dilated cardiomyopathy.","authors":"W Javed, R Tomoaia, M Farooq, B Chambers, I Botis, Z Goh, B Brown, L A Brown, J Farley, H Xue, E Levelt, E Dall'Armellina, J P Greenwood, P Kellman, S Plein, P P Swoboda","doi":"10.1093/ehjci/jeaf234","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf234","url":null,"abstract":"<p><strong>Aims: </strong>To investigate the distribution of myocardial fibrosis and patterns of tissue characteristics on cardiovascular magnetic resonance (CMR) between athletes with LV dilatation and mild DCM patients.</p><p><strong>Methods and results: </strong>We prospectively recruited male cyclists/triathletes aged ≥50y who undertook ≥10h/week of exercise for ≥15y along with age/sex-matched patients with non-ischaemic heart failure (HF). Participants underwent clinical assessment, 12-lead ECG, stress-perfusion CMR with fibrosis assessment and parametric tissue mapping.Following CMR, included participants in both groups had LVEF>40% and LVEDVi>110ml/m2 without ischaemic heart disease or significant cardiac pathology on CMR likely to cause HF.Of 113 participants (64 athletes, 49 mild DCM patients), athletes with fibrosis demonstrated a greater prevalence of inferolateral fibrosis (87.5% vs 50.0%, P=0.002) whereas inferoseptal fibrosis was more common in mild DCM patients (45.8% vs 9.4%, P=0.002).Native T1 (1249.0±38.1 vs 1308.3±47.1ms,P<0.001) and extracellular volume (ECV) (22.0±2.1 vs 25.9±3.5%, P<0.001) were lower in athletes. Athletes had greater right ventricular end-diastolic volume indexed to body surface area (RVEDVi) (121.0±14.3 vs 97.6±25.2%, P<0.001), myocardial perfusion reserve (MPR) (3.65±1.30 vs 2.76±0.92,P<0.001) and stress myocardial blood flow (MBF) (2.09±0.70 vs 1.62±0.66,P<0.001) than mild DCM patients.On receiver-operator curve analysis, native T1 (area under curve (AUC) 0.89,P<0.001), ECV (AUC 0.85,P<0.001), RVEDVi (AUC 0.81, P<0.001) and stress MBF (AUC 0.68,P=0.002) were able to differentiate between groups.</p><p><strong>Conclusion: </strong>Septal fibrosis is rare amongst veteran athletes with LV dilation in contrast to mild DCM patients. Native T1, ECV and RVEDVi can also discriminate between these overlapping phenotypes which may be clinically useful.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}