European Heart Journal - Cardiovascular Imaging最新文献

{"title":"The Role of FDG PET/CT in Assessing Cardiac Sarcoidosis with No High-Risk Cardiac Features and Normal CMR.","authors":"F Shuduyeva, A L M Bakker, F Akdim, R G M Keijsers, M Veltkamp, J C Grutters, M C Post, H Mathijssen","doi":"10.1093/ehjci/jeaf074","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf074","url":null,"abstract":"<p><strong>Background: </strong>Diagnosing cardiac sarcoidosis (CS) is challenging due to the variable presentation and the lack of consensus on optimal screening strategies. Early identification is critical to prevent adverse outcomes. This study evaluates the role of FDG-PET/CT in assessing CS in patients with no high-risk cardiac features and normal cardiac magnetic resonance (CMR).</p><p><strong>Methods: </strong>This retrospective, single-centre cohort included biopsy-confirmed extracardiac sarcoidosis patients who underwent CMR and FDG-PET/CT. Patients with no high-risk cardiac features and normal CMR were included. The primary outcome was the diagnostic value of FDG-PET/CT in the assessment for CS by a multidisciplinary team (MDT). Secondary outcome included the occurrence of adverse cardiac events.</p><p><strong>Results: </strong>In total, 305 (94.1%) patients were classified as \"unlikely CS\", 17 (5.3%) as \"possible CS\" and 2 (0.6%) as \"probable CS\". Cardiac FDG uptake was observed in 69 of 324 patients (21.3%). Within the MDT, FDG-PET/CT findings demonstrated limited diagnostic value, as 55.2% with uptake patterns suggestive of CS were ultimately classified as \"unlikely CS\" based on other clinical and imaging findings. During a median follow-up of 38.1 months, the overall event rate was low: 15 events (3.4%; annualized 1.1%), with all five cardiac deaths occurring in the \"unlikely CS\" group. Only five of 69 patients (7.2%) with cardiac FDG uptake experienced an adverse cardiac event.</p><p><strong>Conclusion: </strong>FDG-PET/CT offers limited diagnostic and prognostic value in sarcoidosis patients with no high-risk cardiac features and normal CMR. Our findings confirm that this population has a low risk of adverse cardiac events.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A very late intracardiac myxoid liposarcoma metastasis.","authors":"Giorgio Moschovitis, Sandra Leoni Parvex, Giorgio Treglia, Stefanos Demertzis, Anna Giulia Pavon","doi":"10.1093/ehjci/jeae308","DOIUrl":"10.1093/ehjci/jeae308","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"589"},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between Duke, European Society of Cardiology 2015, International Society for Cardiovascular Infectious Diseases 2023, and European Society of Cardiology 2023 criteria for the diagnosis of transcatheter aortic valve replacement-related infective endocarditis.","authors":"Inès Boufoula, Mary Philip, Florent Arregle, Laetitia Tessonnier, Serge Camilleri, Sandrine Hubert, Jean-Paul Casalta, Frédérique Gouriet, Laurence Camoin-Jau, Alberto Riberi, Yassine Lemrini, Julien Mancini, Adrien Lemaignen, Fanny Dion, Nicolas Chane-Sone, Claire Lucas, Sébastien Renard, Anne-Claire Casalta, Olivier Torras, Pierre Ambrosi, Frédéric Collart, Anne Bernard, Gilbert Habib","doi":"10.1093/ehjci/jeae310","DOIUrl":"10.1093/ehjci/jeae310","url":null,"abstract":"<p><strong>Aims: </strong>Transcatheter aortic valve replacement-related infective endocarditis (TAVR-IE) is associated with a poor prognosis. TAVR-IE diagnosis is challenging, and benefits of the most recent classifications [European Society of Cardiology (ESC)-2015, International Society for Cardiovascular Infectious Diseases (ISCVID)-2023, and ESC-2023] have not been compared with the conventional Duke criteria on this population. The primary objective was to compare the diagnostic value of the Duke, ESC-2015, ISCVID-2023, and ESC-2023 criteria for the diagnosis of TAVR-IE. The secondary objectives were to determine which criteria increase the diagnostic accuracy of each classification and to evaluate in-hospital and 1-year mortality of TAVR-IE.</p><p><strong>Methods and results: </strong>From January 2015 to May 2022, 92 patients with suspected TAVR-IE were retrospectively included in two French centres, including 82 patients with definite TAVR-IE and 10 patients with rejected TAVR-IE as defined by expert consensus. Duke classification yielded a sensitivity of 65% [95% confidence interval (CI): 53-75%] and a specificity of 100% (95% CI: 69-100%) for the diagnosis of TAVR-IE. ESC-2015 classification increased Duke criterion sensitivity from 65 to 73% (P = 0.016) but decreased specificity from 100 to 90%. ISCVID-2023 and ESC-2023 also increased Duke criterion sensitivity from 65 to 76% (P = 0.004) and 77% (P = 0.002), respectively, but also decreased specificity from 100 to 90%. A positive 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) was the most helpful criterion, as 10 patients (11%) were correctly reclassified. In-hospital mortality after TAVR-IE was 21% and 1-year mortality was 38%.</p><p><strong>Conclusion: </strong>A multimodality imaging approach, including 18F-FDG PET/CT and gated cardiac CT, is the cornerstone of TAVR-IE diagnosis and explains the higher sensitivity of ESC-2015 and recent classifications compared with Duke criteria.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"532-544"},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: An uncommon cause of iatrogenic tricuspid valve regurgitation.","authors":"","doi":"10.1093/ehjci/jeaf018","DOIUrl":"10.1093/ehjci/jeaf018","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"592"},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult-type Scimitar Syndrome.","authors":"Tomoro Morikawa, Akiyuki Kotoku, Akihiro Tsuji, Takeshi Ogo, Tatsuya Nishii","doi":"10.1093/ehjci/jeaf076","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf076","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimated total amyloid burden from 18F-florbetaben positron emission tomography predicts all-cause mortality in light-chain cardiac amyloidosis.","authors":"Giuseppe Vergaro, Alberto Aimo, Dario Genovesi, Lucas Soares Bezerra, Vincenzo Castiglione, Iacopo Fabiani, Andrea Barison, Giorgia Panichella, Maria Livia Del Giudice, Lara Camerini, Giovanni Dugo, Olena Chubuchna, Assuero Giorgetti, Gabriele Buda, Michele Emdin","doi":"10.1093/ehjci/jeae332","DOIUrl":"10.1093/ehjci/jeae332","url":null,"abstract":"<p><strong>Aims: </strong>The positron emission tomography (PET) tracer 18F-florbetaben is a promising diagnostic tool for light-chain cardiac amyloidosis (AL-CA). A greater cardiac uptake might signal more amyloid burden and a worse outcome. We aimed to assess the prognostic significance of 18F-florbetaben uptake in AL-CA.</p><p><strong>Methods and results: </strong>Consecutive patients with AL-CA underwent 18F-florbetaben PET scans. Total amyloid burden (TAB; calculated as mean standardized uptake value multiplied by molecular volume) was assessed in the left and right ventricles (LV/RV) in early (5-15') and late (50-60') acquisitions. The endpoint was all-cause mortality. Forty patients (median age 69 years, 73% males, Mayo 2004 Stage III in 80%) underwent 18F-florbetaben PET with a median time from tissue biopsy of 21 days (interquartile range, IQR 7-83). Late LV TAB, but not early LV TAB, correlated with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity (hs)-troponin T. Over 13 months after the PET scan (IQR 5-21), 65% of patients died. A late LV TAB ≥273 cm3 (cut-off derived from spline curve analysis) predicted 18 and 24 month all-cause mortality independently from baseline variables, including NT-proBNP, hs-troponin T, and Mayo 2004 stage. Late RV TAB ≥135 cm3 independently predicted 18 and 24 month all-cause mortality. Patients with both late LV and RV TAB ≥ cut-offs had a shorter survival than those with only LV TAB ≥ cut-off and those with TAB in both ventricles < cut-offs (Log-rank 16.52, P < 0.001).</p><p><strong>Conclusion: </strong>18F-florbetaben PET imaging offers valuable prognostic information in AL-CA. Values of late TAB measured in the LV and RV are strong predictors of all-cause mortality.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"500-508"},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interrupted aortic arch with complete atrioventricular canal defect: insights from CT imaging.","authors":"Wei-Feng Yan, Yue Gao, Chen-Yan Min, Jin Wang","doi":"10.1093/ehjci/jeae298","DOIUrl":"10.1093/ehjci/jeae298","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"582"},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mechanistic interaction between mechanical dyssynchrony and filling pressure in cardiac resynchronisation therapy candidates.","authors":"Ahmed S Beela, Claudia A Manetti, Frits W Prinzen, Tammo Delhaas, Lieven Herbots, Joost Lumens","doi":"10.1093/ehjci/jeae286","DOIUrl":"10.1093/ehjci/jeae286","url":null,"abstract":"<p><strong>Aims: </strong>Both left ventricular (LV) mechanical dyssynchrony and filling pressure have been shown to be associated with outcome in heart failure patient treated with cardiac resynchronisation therapy (CRT). To investigate the mechanistic link between mechanical dyssynchrony and filling pressure and to assess their combined prognostic value in CRT candidates.</p><p><strong>Methods and results: </strong>Left atrial pressure (LAP) estimation and quantification of mechanical dyssynchrony were retrospectively performed in 219 CRT patients using echocardiography. LAP was elevated (eLAP) in 49% of the population, normal (nLAP) in 40%, and indeterminate in 11%. CRT response was defined as per cent-decrease in LV end-systolic volume after 12 ± 6 months CRT. Clinical endpoint was all-cause mortality during 4.8 years (interquartile range: 2.7-6.0 years). To investigate the mechanistic link between mechanical dyssynchrony and filling pressure, the CircAdapt computer model was used to simulate cardiac mechanics and haemodynamics in virtual hearts with left bundle branch block (LBBB) and various causes of increased filling pressure. Patients with nLAP had more significant mechanical dyssynchrony than those with eLAP. The combined assessment of both parameters before CRT was significantly associated with reverse LV remodelling and post-CRT survival. Simulations revealed that mechanical dyssynchrony is attenuated by increased LV operational chamber stiffness, regardless of whether it is caused by passive or active factors, explaining the link between mechanical dyssynchrony and filling pressure.</p><p><strong>Conclusion: </strong>Our combined clinical-computational data demonstrate that in patients with LBBB, the presence of mechanical dyssynchrony indicates relatively normal LV compliance and low filling pressure, which may explain their strong association with positive outcomes after CRT.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"424-434"},"PeriodicalIF":6.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Case of Acute Focal Myocarditis Caused by Gilteritinib, a Novel Tyrosine Kinase Inhibitor.","authors":"Swagata Patnaik, Alexander Levy, Gina LaRocca, Gagan Sahni, Solomon W Bienstock","doi":"10.1093/ehjci/jeaf077","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf077","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masquerading ST-elevation myocardial infarction in patients with soft tissue sarcoma treated by pazopanib.","authors":"Daiki Suzuki, Tomoo Nagai, Takeshi Ijichi, Yohei Ohno, Yuji Ikari","doi":"10.1093/ehjci/jeaf064","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf064","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}