European Heart Journal - Cardiovascular Imaging最新文献

{"title":"Right ventricular strain in cardiac amyloidosis: a missing link becomes a clinical target.","authors":"Benay Ozbay, Leyla Elif Sade","doi":"10.1093/ehjci/jeaf225","DOIUrl":"10.1093/ehjci/jeaf225","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1662-1663"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of right ventricular longitudinal strain assessed by multimodal imaging in amyloidosis: systematic review and meta-analysis.","authors":"Javier Herrera-Flores, Robin W M Vernooij, Arjun K Ghosh, Ashutosh Wechalekar, Richard K Cheng, Kalliopi Keramida, Manuel Anguita, Pedro L Sanchez, Candelas Perez Del Villar, Cristian Herrera-Flores","doi":"10.1093/ehjci/jeaf216","DOIUrl":"10.1093/ehjci/jeaf216","url":null,"abstract":"<p><strong>Aims: </strong>Amyloidosis is a progressive and often fatal disease, with right ventricular (RV) involvement emerging as critical determinant of outcomes. This meta-analysis sought to evaluate the prognostic significance of RV longitudinal strain parameters in patients with amyloidosis.</p><p><strong>Methods and results: </strong>Eligible studies reporting on the association between RV free-wall longitudinal strain (RV-FWLS) and RV global longitudinal strain (RV-GLS) assessed by echocardiography or cardiac magnetic resonance (CMR) with adverse outcomes were included. Using an inversely weighted random-effects meta-analysis, pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated for all-cause mortality and a composite endpoint of all-cause death or heart failure hospitalization per 1% lower RV strain values. Eighteen studies with low-to-moderate risk of bias (Newcastle-Ottawa scale) and encompassing 1772 patients [mean age 68.8 ± 8.8 years; 57.3% with light-chain amyloidosis (AL)], were analysed. 210 patients experienced the composite outcome (median [inter-quartile range] follow-up: 1.5 [0.6] years) and 628 died [median follow-up: 2.6 (1.6) years]. 2D speckle-tracking RV-FWLS was associated with all-cause mortality (HR: 1.10; 95% CI: 1.07-1.13; I² = 8.6%) and the composite outcome (HR: 1.06; 95% CI: 1.02-1.10; I² = 0%). Similarly, 2D speckle-tracking RV-GLS was associated with all-cause mortality (HR: 1.10; 95% CI: 1.07-1.13; I² = 8.6%). Subgroup and meta-regression analysis confirmed consistency across amyloid subtypes, study design, presence of cardiac involvement, follow-up duration, and strain analysis software. In AL amyloidosis, CMR-based RV-GLS also predicted all-cause mortality (HR: 1.06; 95% CI: 1.03-1.09; I² = 0%).</p><p><strong>Conclusion: </strong>RV longitudinal strain parameters are powerful and robust predictors of adverse outcomes in amyloidosis.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1644-1661"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative cardiovascular magnetic resonance myocardial perfusion can discriminate significant cardiac allograft vasculopathy: a multi-centre study.","authors":"R Jablonowski, H B Andersson, C Fogarasi, H Engblom, H Arheden, P Kellman, M Carlsson, M Melin, I H Löfman, J Nickander, O Ö Braun","doi":"10.1093/ehjci/jeaf201","DOIUrl":"10.1093/ehjci/jeaf201","url":null,"abstract":"<p><strong>Aims: </strong>Cardiac allograft vasculopathy (CAV) is a significant complication that contributes to both morbidity and mortality after heart transplantation. The aim of this study was to (i) assess if quantitative cardiovascular magnetic resonance (CMR) myocardial perfusion could detect different stages of CAV and (ii) establish a myocardial perfusion reserve (MPR) cut-off for significant CAV.</p><p><strong>Methods and results: </strong>Patients with a heart transplant who had performed a clinical CMR scan and invasive angiography at two centres in Sweden were included in the study (n = 110). Quantitative short-axis perfusion maps were acquired using single-bolus gadolinium contrast, dual-sequence perfusion imaging at rest and during stress. Global myocardial perfusion (MP) was averaged across all segments at rest and stress and MPR was defined as the ratio between stress and rest MP. All invasive angiographies were reported according to the International Heart and Lung Transplantation CAV classification. Patients were classified as follows: 53% (58/110) as CAV0, 38% (42/110) as CAV1, and 9% (10/110) as CAV2-3. There was a gradual decrease of stress MP and MPR with increased CAV grade. The MPR could discriminate CAV2-3 with an area under the curve-receiver operating characteristic of 0.88, 95% confidence interval 0.78-0.98, and using a cut-off of 2.2, the sensitivity was 100%, specificity was 68%, and positive and negative predictive values were 21 and 100%.</p><p><strong>Conclusion: </strong>In this multi-centre retrospective study, MPR assessed by CMR could discriminate CAV2-3 with both high sensitivity and negative predictive value and a cut-off of MPR 2.2 is suggested.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1623-1630"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redefining the risk of major arrhythmic events in non-ischaemic cardiomyopathy: insights from the DERIVATE-NICM study.","authors":"Andrea Igoren Guaricci, Nazario Carrabba, Salvatore Mario Romano, Marco Chiostri, Laura Fusini, Andrea Baggiano, Saima Mushtaq, Alessandra Volpe, Raffaele Abete, Giovanni Donato Aquaro, Andrea Barison, Paolo Basile, Jan Bogaert, Leonardo Calo', Giovanni Camastra, Samuela Carigi, Grazia Casavecchia, Stefano Censi, Gloria Cicala, Marco Matteo Ciccone, Carlo N De Cecco, Manuel De Lazzari, Gabriella Di Giovine, Monica Dobrovie, Marta Focardi, Nicola Gaibazzi, Annalaura Gismondi, Matteo Gravina, Marco Guglielmo, Chiara Lanzillo, Massimo Lombardi, Valentina Lorenzoni, Jordi Lozano-Torres, Davide Margonato, Chiara Martini, Francesca Marzo, Pier-Giorgio Masci, Ambra Masi, Claudio Moro, Giuseppe Muscogiuri, Alberto Nese, Alessandro Palumbo, Anna Giulia Pavon, Patrizia Pedrotti, Martina Perazzolo Marra, Silvia Pradella, Cristina Presicci, Mark G Rabbat, Claudia Raineri, Jose' F Rodriguez-Palomares, Guillem Casas, Eduardo Rodenas-Alesina, Alessandro Giustiniani, Stefano Sbarbati, U Joseph Schoepf, Angelo Squeri, Nicola Sverzellati, Rolf Symons, Emily Tat, Mauro Timpani, Giancarlo Todiere, Adele Valentini, Akos Varga-Szemes, Juerg Schwitter, Gianluca Pontone","doi":"10.1093/ehjci/jeaf198","DOIUrl":"10.1093/ehjci/jeaf198","url":null,"abstract":"<p><strong>Aims: </strong>Selection of the patients for implantable cardioverter defibrillator primary prevention therapy in non-ischaemic cardiomyopathy (NICM) needs to be improved. To evaluate the additional prognostic value of a new cardiac magnetic resonance (CMR) score based on late gadolinium enhancement (LGE) pattern distribution (DERIVATE Risk Score 2.0) when compared with previously published DERIVATE Risk Score 1.0, which is based solely on quantitative parameters, in a cohort of NICM patients enrolled in the DERIVATE registry.</p><p><strong>Methods and results: </strong>One thousand three hundred and eighty-four NICM patients with chronic heart failure and left ventricular ejection fraction (LVEF) < 50% were evaluated for primary sudden cardiac death prevention therapy. Major adverse arrhythmic cardiac events (MAACEs) were the primary endpoint. During a median follow-up of 959 days, MAACE occurred in 128 (9.2%) patients. In the multivariate analyses, male gender [hazard ratio (HR): 1.605 (95% confidence interval, CI: 1.051-2.451); P = 0.028], LVEF per point % [HR: 0.977 (95% CI: 0.961-0.993); P = 0.005] and presence and location of midwall LGE [weighted HR: 1.066 (95% CI: 1.045-1.086), P < 0.001] were independent predictors of MAACE. A multi-parametric CMR-weighted predictive-derived score (DERIVATE Risk Score 2.0) provided a higher additional prognostic value vs. transthoracic echocardiography-LVEF cut-off of 35% when compared with the previous published DERIVATE Risk Score 1.0 with a net reclassification improvement of 54.52% (95% CI: 36.52-72.52%; P < 0.001). These findings were confirmed in the validation cohort.</p><p><strong>Conclusion: </strong>The presence of midwall LGE, but also the location of scar, confers an added and independent MAACE risk to a large NICM population influencing the choice of treatment.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1609-1619"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-year functional and structural effects of mavacamten in obstructive hypertrophic cardiomyopathy: a comprehensive CMR study.","authors":"Katharina Seuthe, Roman Pfister, Roman Johannes Gertz, Henrik Ten Freyhaus, Jan Paul Janssen, Merve Kural, Athanasios Feidakis, Carsten Gietzen, David Maintz, Stephan Baldus, Lenhard Pennig, Kenan Kaya","doi":"10.1093/ehjci/jeaf231","DOIUrl":"10.1093/ehjci/jeaf231","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1685-1687"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory Achilles tendinous and tuberous xanthomas in homozygous familial hypercholesterolaemia.","authors":"Masahiro Sasaki, Nobuhiro Tahara, Yayoi Sakata, Shuichi Tanoue, Yoshihiro Fukumoto","doi":"10.1093/ehjci/jeaf164","DOIUrl":"10.1093/ehjci/jeaf164","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1694"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regression of late gadolinium enhancement in a case of eosinophilic granulomatous polyangiitis with cardiac involvement.","authors":"Pok-Tin Tang, Jonathan Raby, Jessica Gunn, Andrew J M Lewis","doi":"10.1093/ehjci/jeaf163","DOIUrl":"10.1093/ehjci/jeaf163","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1693"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fistulization of free-wall myocardial abscess into the pericardium: a life-threatening complication of infective endocarditis.","authors":"Hussam Alsawidi, Hui Wang, Ashraf Haidarah, Chen Mao","doi":"10.1093/ehjci/jeaf172","DOIUrl":"10.1093/ehjci/jeaf172","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1696"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between inflammatory biomarkers, chronic stress, and pericoronary adipose tissue attenuation obtained with coronary CT.","authors":"Tobia Albertini, Marc Dörner, Andreas A Giannopoulos, Roland von Känel, Dominik C Benz, Nidaa Mikail, Daniel de Wilde, Clarissa D Voegel, Tina M Binz, Philipp A Kaufmann, Catherine Gebhard, Ronny R Buechel, Aju P Pazhenkottil","doi":"10.1093/ehjci/jeaf217","DOIUrl":"10.1093/ehjci/jeaf217","url":null,"abstract":"<p><strong>Aims: </strong>Pericoronary adipose tissue (PCAT) attenuation is a novel imaging biomarker of coronary inflammation associated with an increased risk of coronary artery disease (CAD). However, no studies have examined the relationship between chronic stress and PCAT. This study aimed to evaluate the intersection between chronic stress, inflammatory biomarkers, coronary plaque features, and PCAT attenuation.</p><p><strong>Methods and results: </strong>A total of 98 participants without known CAD were included. PCAT attenuation, total plaque volume (TPV) quantification, and vulnerable plaque features were assessed by coronary CT angiography and chronic stress was measured by hair cortisol concentration (HCC) and vital exhaustion questionnaire. Regression models were used to analyse associations of PCAT with the inflammatory biomarkers interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α), TPV, vulnerable plaque features, and coronary stenosis. Moderating analyses were performed to test whether chronic stress modulated the association between inflammatory biomarkers and PCAT attenuation. PCAT attenuation was significantly associated with IL-6 (mean difference 1.05, 95% CI 0.21-1.89, P = 0.014), TNF-α (mean difference 0.60, 95% CI 0.06-1.13, P = 0.027), and a greater TPV (mean difference 3.51, 95% CI 0.02-7.00, P = 0.048), but not vulnerable plaque features or coronary stenosis. HCC (interaction term -0.12, 95% CI -0.22 to -0.02, P = 0.019) and vital exhaustion (interaction term 0.13, 95% CI 0.01-0.25, P = 0.024) moderated the relationship between IL-6, but not TNF-α, and PCAT attenuation.</p><p><strong>Conclusion: </strong>This study suggests that circulating inflammatory biomarkers are associated with PCAT attenuation, which was further correlated with TPV. Chronic stress may moderate the relationship between inflammatory cytokines and PCAT attenuation.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1664-1672"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Imaging-based method to quantify left ventricular diastolic pressures.","authors":"","doi":"10.1093/ehjci/jeaf242","DOIUrl":"10.1093/ehjci/jeaf242","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"1688"},"PeriodicalIF":6.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}