C Noel Bairey Merz, Robert O Bonow, Mercedes Carnethon, Filippo Crea, Joseph A Hill, Harlan M Krumholz, Roxana Mehran, Erica S Spatz
{"title":"The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.","authors":"C Noel Bairey Merz, Robert O Bonow, Mercedes Carnethon, Filippo Crea, Joseph A Hill, Harlan M Krumholz, Roxana Mehran, Erica S Spatz","doi":"10.1093/ehjci/jeaf094","DOIUrl":"https://doi.org/10.1093/ehjci/jeaf094","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murray F Matangi, Marie-France Hétu, David W J Armstrong, Jonas Shellenberger, Daniel Brouillard, Josh Baker, Ana Johnson, Nicholas Grubic, Hannah Willms, Amer M Johri
{"title":"Carotid plaque score is associated with 10-year major adverse cardiovascular events in low-intermediate risk patients referred to a general cardiology community clinic.","authors":"Murray F Matangi, Marie-France Hétu, David W J Armstrong, Jonas Shellenberger, Daniel Brouillard, Josh Baker, Ana Johnson, Nicholas Grubic, Hannah Willms, Amer M Johri","doi":"10.1093/ehjci/jeae153","DOIUrl":"10.1093/ehjci/jeae153","url":null,"abstract":"<p><strong>Aims: </strong>Atherosclerotic carotid plaque assessments have not been integrated into routine clinical practice due to the time-consuming nature of both imaging and measurements. Plaque score, Rotterdam method, is simple, quick, and only requires 4-6 B-mode ultrasound images. The aim was to assess the benefit of plaque score in a community cardiology clinic to identify patients at risk for major adverse cardiovascular events (MACE).</p><p><strong>Methods and results: </strong>Patients ≥ 40 years presenting for risk assessment were given a carotid ultrasound. Exclusions included a history of vascular disease or MACE and being >75 years. Kaplan-Meier curves and hazard ratios were performed. The left and right common carotid artery (CCA), bulb, and internal carotid artery were given 1 point per segment if plaque was present (plaque scores 0-6). Administrative data holdings at ICES were used for 10-year event follow-up. Of 8472 patients, 60% were females (n = 5121). Plaque was more prevalent in males (64% vs. 53.9%; P < 0.0001). The 10-year MACE cumulative incidence estimate was 6.37% with 276 events (males 6.9% vs. females 6.0%; P = 0.004). Having both maximal CCA intima media thickness < 1.00 mm and plaque score = 0 was associated with less events. A plaque score < 2 was associated with a low 10-year event rate (4.1%) compared with 2-4 (8.7%) and 5-6 (20%).</p><p><strong>Conclusion: </strong>A plaque score ≥ 2 can re-stratify low-intermediate risk patients to a higher risk for events. Plaque score may be used as a quick assessment in a cardiology office to guide treatment management of patients.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"714-724"},"PeriodicalIF":6.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141497515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hee Jeong Lee, Na Young Kim, Dae-Young Kim, Jang-Won Son, Kang-Un Choi, SeonHwa Lee, In-Cheol Kim, Kyu-Yong Ko, Kyung Eun Ha, Seo-Yeon Gwak, Kyu Kim, Jiwon Seo, Hojeong Kim, Chi Young Shim, Jong-Won Ha, Hyungseop Kim, Geu-Ru Hong, Iksung Cho, Young Joo Suh
{"title":"Selecting the optimal candidates for percutaneous mitral valvuloplasty using multi-modality imaging.","authors":"Hee Jeong Lee, Na Young Kim, Dae-Young Kim, Jang-Won Son, Kang-Un Choi, SeonHwa Lee, In-Cheol Kim, Kyu-Yong Ko, Kyung Eun Ha, Seo-Yeon Gwak, Kyu Kim, Jiwon Seo, Hojeong Kim, Chi Young Shim, Jong-Won Ha, Hyungseop Kim, Geu-Ru Hong, Iksung Cho, Young Joo Suh","doi":"10.1093/ehjci/jeae334","DOIUrl":"10.1093/ehjci/jeae334","url":null,"abstract":"<p><strong>Aims: </strong>This study compared echocardiography (echo) and cardiac computed tomography (CT) in measuring the Wilkins score and evaluated the potential added benefit of CT in predicting immediate percutaneous mitral valvuloplasty (PMV) outcomes in rheumatic mitral stenosis (MS) patients deemed eligible for PMV by echo.</p><p><strong>Methods and results: </strong>From a multicentre registry of 3,140 patients with at least moderate MS, we included 96 patients (age 56.4 ± 11.5 years, 81% female) eligible for PMV based on echo Wilkins score (≤9) who underwent PMV and had measurable CT and echo images. We compared Wilkins scores from both modalities and analysed their relationship with unsuccessful procedural outcomes, defined as sub-optimal post-procedural mitral valve area (<1.5 cm2) or newly developed mitral regurgitation Grade ≥III. The mean CT score was higher than the echo score (8.0 ± 2.4 vs. 7.3 ± 1.2 points, P = 0.005). Procedural success was achieved in 65 (67.7%) patients. Unsuccessful results occurred in 31 patients, primarily in intermediate echo score (7-9 points) group. Among patients with intermediate echo scores, 90% had high CT scores (≥9), which were associated with significantly higher rates of unsuccessful PMV compared with lower CT scores (61.1 vs. 18.9%, P < 0.001).</p><p><strong>Conclusion: </strong>CT-derived Wilkins scores were higher than echo-derived scores, with the most significant discrepancy in the intermediate echo score group. CT identified a subgroup of patients at higher risk for unsuccessful PMV among those with intermediate echo-based feasibility. Patients with intermediate echo-based PMV feasibility may benefit from CT-based reclassification, potentially improving patient selection and procedural outcomes.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"705-711"},"PeriodicalIF":6.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The emerging role of left atrioventricular coupling index in heart failure: a new frontier for cardiac magnetic resonance.","authors":"Federico Fortuni, Claudio Bernetti, Erberto Carluccio","doi":"10.1093/ehjci/jeaf047","DOIUrl":"10.1093/ehjci/jeaf047","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"618-619"},"PeriodicalIF":6.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivan Lechner, Alex Kaser, Martin Reindl, Sebastian J Reinstadler
{"title":"Global longitudinal strain and beta-blockers: rethinking their roles in post-AMI patients with preserved ejection fraction.","authors":"Ivan Lechner, Alex Kaser, Martin Reindl, Sebastian J Reinstadler","doi":"10.1093/ehjci/jeaf039","DOIUrl":"10.1093/ehjci/jeaf039","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"628-629"},"PeriodicalIF":6.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jwan A Naser, Hossam Ibrahim, Kartik Andi, Christopher G Scott, Patricia A Pellikka, Austin M Kennedy, Heidi M Connolly, Vuyisile T Nkomo, Maurice Enriquez-Sarano, Sorin V Pislaru, Carole A Warnes, Charles C Jain, Barry A Borlaug, Alexander C Egbe
{"title":"Prevalence, aetiology, and outcomes of native pulmonary regurgitation in the general adult population.","authors":"Jwan A Naser, Hossam Ibrahim, Kartik Andi, Christopher G Scott, Patricia A Pellikka, Austin M Kennedy, Heidi M Connolly, Vuyisile T Nkomo, Maurice Enriquez-Sarano, Sorin V Pislaru, Carole A Warnes, Charles C Jain, Barry A Borlaug, Alexander C Egbe","doi":"10.1093/ehjci/jeaf011","DOIUrl":"10.1093/ehjci/jeaf011","url":null,"abstract":"<p><strong>Aims: </strong>Pulmonary regurgitation (PR) after reparative intervention for congenital heart disease has been studied extensively. However, the burden, distribution of causes, and outcome of PR in adults is unknown. The study aimed to evaluate the prevalence, types, and outcomes of moderate/severe PR in adults in the community setting.</p><p><strong>Methods and results: </strong>A total of 398 adult residents of Olmsted County who had clinically indicated echocardiography 2004-2023 at Mayo Clinic, Rochester, and had moderate or severe PR were identified retrospectively. The median age was 77 years, 48% were females, and 61 (51%) had severe PR. The age- and sex-adjusted US prevalence was 0.11% (vs. 0.67% for ≥moderate tricuspid regurgitation). Moderate/severe PR was due to pulmonary hypertension in 77%, congenital/iatrogenic in 11%, primary pulmonary valve disease in 2% (88% due to carcinoid), and idiopathic isolated in 10%. In contrast, severe PR was due to congenital/iatrogenic disease in 52%, pulmonary hypertension in 39%, primary PR in 5%, and isolated idiopathic in 3%. The all-cause mortality rate per 100 person-year was 73 in primary (mostly carcinoid) PR, 16 in pulmonary hypertension-related PR (not different vs. propensity-matched patients without PR), and 6 in isolated idiopathic PR (not different vs. matched patients without PR).</p><p><strong>Conclusion: </strong>Moderate or severe PR had a lower prevalence vs. TR. The most frequent cause was pulmonary hypertension for ≥moderate PR and congenital/iatrogenic for severe PR. Mortality in patients with acquired ≥moderate PR appeared to be related to the underlying cause, with no excess mortality compared with matched patients without PR. Whether specifically severe PR confers excess mortality requires future investigation.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"695-702"},"PeriodicalIF":6.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lukas Stolz, Simon Schmid, Julius Steffen, Philipp M Doldi, Ludwig T Weckbach, Thomas J Stocker, Kornelia Löw, Carolin Fröhlich, Julius Fischer, Magda Haum, Hans D Theiss, Konstantin Stark, Konstantinos Rizas, Sven Peterss, Michael Näbauer, Christian Hagl, Steffen Massberg, Jörg Hausleiter, Simon Deseive
{"title":"Prognostic impact of left- and right-atrial strain in patients undergoing transcatheter aortic valve replacement.","authors":"Lukas Stolz, Simon Schmid, Julius Steffen, Philipp M Doldi, Ludwig T Weckbach, Thomas J Stocker, Kornelia Löw, Carolin Fröhlich, Julius Fischer, Magda Haum, Hans D Theiss, Konstantin Stark, Konstantinos Rizas, Sven Peterss, Michael Näbauer, Christian Hagl, Steffen Massberg, Jörg Hausleiter, Simon Deseive","doi":"10.1093/ehjci/jeae322","DOIUrl":"10.1093/ehjci/jeae322","url":null,"abstract":"<p><strong>Aims: </strong>Data on the prognostic value of left- and right-atrial strain after transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS) are limited. Aim of this study was to evaluate outcomes of patients undergoing TAVR stratified by left- and right-atrial strain.</p><p><strong>Methods and results: </strong>Using data from a high-volume academic centre, left- and right-atrial reservoir strain (LASr and RASr) was obtained in patients who underwent TAVR for severe AS from 2018 until 2021. Patients were stratified into groups with normal atrial function (LASr and RASr normal), uni-atrial strain impairment (LASr or RASr impaired), and bi-atrial strain impairment (LASr and RASr impaired). Endpoints were 3 year survival, symptomatic improvement as assessed by New York Heart Association functional class (NYHA class) as well as technical and device success defined by the Valve Academic Research Consortium composite endpoints. The study included 1888 patients at a mean age of 81.0 ± 7.8 years (44.3% women). Mean LASr and RASr were 16.5 ± 9.4% and 21.6 ± 12.4%, respectively. Optimized cut-offs for mortality prediction were 15.5% for LASr and 15.0% for RASr. LASr and RASr were normal in 751 patients (39.8%). Impairment of either right-atrium (RA) or left-atrium (LA) strain was observed in 633 patients (33.5%) and 504 patients (26.7%) presented with reduced LA and RA strain. While impairment of either LASr or RASr was associated with a 1.7-fold increased risk of 3 year all-cause mortality after adjustment for multiple confounders (95% confidence interval [CI] 1.2-2.5, P = 0.005), bi-atrial strain impairment exhibited an even higher 3 year mortality risk (Hazard ratio 2.5, 95% CI 1.7-3.6, P < 0.001).</p><p><strong>Conclusion: </strong>Pre-procedural assessment of atrial strain is associated with increased 3 year mortality and might facilitate outcome prediction and patient selection in patients undergoing TAVR for severe AS.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"664-673"},"PeriodicalIF":6.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}