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Role of genetics in the Primary Biliary Cirrhosis; withthe presentation of the three sisters 遗传学在原发性胆汁性肝硬化中的作用在三姐妹的介绍下
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81913
T. Temel, P. Yildiz, A. Özakyol
{"title":"Role of genetics in the Primary Biliary Cirrhosis; withthe presentation of the three sisters","authors":"T. Temel, P. Yildiz, A. Özakyol","doi":"10.29333/EJGM/81913","DOIUrl":"https://doi.org/10.29333/EJGM/81913","url":null,"abstract":"Objective:There is growing evidence of genetic susceptibility and environmental factors lead to primary biliary cirrhosis (PBC). In particular, family members of an\u0000infected individual can have higher risk of developing PBC. Here we present two of three siblings who did not have any clinical symptoms.Case:Three siblings, who are 44, 53 and 51 years old respectively, were diagnosed as PBC. One of them excepted and the others were asymptomatic and the 44 yearsold\u0000women has a known results of PBC such as icteric sclera, ascites, prolonged prothrombin time, elevated INR and splenomegaly. On the contrary, other two sibling\u0000did not have symptoms associated with PBC but the screening tests diagnosed PBC.Discussion:In conclusion that familial PBC is not rare, that it is related to maternally inherited factors. PBC may be initially asymptomatic and therefore family\u0000screening is important in the early diagnosis and treatment.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79271578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nasopharyngeal Symptoms caused by Abnormal Inflation of the Endotracheal Tube in Patients undergoing Cervical Spine Surgery 颈椎手术患者气管内管异常膨胀引起的鼻咽症状
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81899
Á. Montiel-Jarquín, Luis Enrique Romero-Morales, R. Lopez, M. Dominguez-Cid, E. García-Cano, M. Romero-Figueroa, R. BARRAGÁN-HERVELLA
{"title":"Nasopharyngeal Symptoms caused by Abnormal Inflation of the Endotracheal Tube in Patients undergoing Cervical Spine Surgery","authors":"Á. Montiel-Jarquín, Luis Enrique Romero-Morales, R. Lopez, M. Dominguez-Cid, E. García-Cano, M. Romero-Figueroa, R. BARRAGÁN-HERVELLA","doi":"10.29333/EJGM/81899","DOIUrl":"https://doi.org/10.29333/EJGM/81899","url":null,"abstract":"Background:Abnormal balloon inflation of the endotracheal tube can cause nasopharyngeal symptoms. The objective is to describe Signs and Symptoms caused by the\u0000Abnormal Insufflated Balloon of the Endotracheal Cannula on patients undergoing Cervical Spine Surgery under General Anesthesia.Methods:Descriptive study, 39 patients underwent cervical spine surgery under general anesthesia, all of them were older than 18 years old and ASA I and II. The\u0000pressure balloon inflation of the endotracheal tube was measured by a manual manometer VBM Medizintechnik GmbH, measurements were made at the beginning of\u0000the procedure, and every hour during the transanesthetic period. The patients underwent a questionnaire about their symptoms on the recovery area and 24 hours\u0000after extubation.Results:39 patients, 59% men, 41% women. Average age was 47, minimum 15 – maximum 77, SD 14.26 years old. The average pressure balloon inflation at the moment\u0000of intubation was 30.7 mmHg and at the moment of extubation was 29.07 mmHg. The symptoms presented on the Recovery Care Unit and at 24 hours were: pain,\u0000inflammation, dysphagia, foreign body sensation.Conclusions:The pressure balloon inflation of the endotracheal cannula is important, because a pressure greater than 30mmHg produce symptoms. Changes on the\u0000patient’s position produced variations on the balloon pressure; therefore, continuous monitorization of the pressure baloon must be done.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80233770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathologically TTF-1 and Calcitonin PositiveLaryngeal Typical Carcinoid Tumor with ElevatedSerum Calcitonin 组织病理学上TTF-1和降钙素阳性咽典型类癌伴血清降钙素升高
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81915
F. R. Tuncturk, L. Uzun, T. Zenginkinet, S. Ozkanlı, M. Kalcıoğlu
{"title":"Histopathologically TTF-1 and Calcitonin PositiveLaryngeal Typical Carcinoid Tumor with ElevatedSerum Calcitonin","authors":"F. R. Tuncturk, L. Uzun, T. Zenginkinet, S. Ozkanlı, M. Kalcıoğlu","doi":"10.29333/EJGM/81915","DOIUrl":"https://doi.org/10.29333/EJGM/81915","url":null,"abstract":"Even with 1% of the incidence, laryngeal neuroendocrine tumors are the second common tumors in larynx; as a subtype, typical carcinoid tumors are extremely\u0000rare. We presented a case of laryngeal typical carcinoid tumor and we discussed diagnostic criteria and treatment of these tumors. A 57-year-old male with a 3\u0000months history of hoarseness was examined endoscopically and a laryngeal mass on left supraglottic area was seen. High levels of serum calcitonin were detected.\u0000The histopathological analysis of biopsy material was typical carcinoid tumor. Laryngeal tumor resection and left neck dissection were performed. The histopathologic\u0000result was TTF 1 and calcitonin positive primer laryngeal typical carcinoid tumor with cervical lymphoid metastasis. Serum calcitonin level returned to normal levels\u0000postoperatively. The distinction between laryngeal carcinoid tumors and metastasis of thyroid medullary carcinoma are difficult histopathologically. So, laryngeal\u0000carcinoid tumors should be kept in mind in these circumstances.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86958744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sitting Buddha position: Sacral agenesis case 坐佛位:骶骨发育不全病例
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81914
O. Güvenç, I. Guler, A. Annagür
{"title":"Sitting Buddha position: Sacral agenesis case","authors":"O. Güvenç, I. Guler, A. Annagür","doi":"10.29333/EJGM/81914","DOIUrl":"https://doi.org/10.29333/EJGM/81914","url":null,"abstract":"Sacral agenesis syndrome (Caudal regression syndrome) is a neural tube defect that is characterized by absence of the vertebral segment that constitutes the sacrum. It\u0000is very rarely seen and generally develops sporadically. Its etiology is influenced by maternal diabetes, genetic factors, teratogenic agents and vascular hypo-perfusion.\u0000It is important to make a diagnosis in the prenatal period. This paper presents a newborn diagnosed with sacral agenesis as a case and discusses this disease in the\u0000light of the latest literature information.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87406760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Affecting Survival in Small Cell Lung Cancer 影响小细胞肺癌生存的因素
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81903
A. Sakin, Erhan Turgut, Muruvvet Aybek, Ahmet Usta, Özgür Koşan, K. Çelik, S. Ozturk, M. Koçer
{"title":"Factors Affecting Survival in Small Cell Lung Cancer","authors":"A. Sakin, Erhan Turgut, Muruvvet Aybek, Ahmet Usta, Özgür Koşan, K. Çelik, S. Ozturk, M. Koçer","doi":"10.29333/EJGM/81903","DOIUrl":"https://doi.org/10.29333/EJGM/81903","url":null,"abstract":"Background:Small cell lung cancer (SCLC) constitutes about 15-25 % of lung cancers with high mortality rate. Herein we observed the effect of parameters at the time\u0000of diagnosis to survival of cases with SCLC.Methods:We evaluated 65 patients who were followed up in our oncology department retrospectively.Results:Tumor location and stage at the time of diagnosis, smoking history, accompanying comorbidities, ECOG PS, laboratory parameters and treatments applied in\u0000pursuit were evaluated. 3-month survival rate of patients was 75.9%, 50.2% for 6-month, 21.4% for 1 year, and 5.5% for 2 years during follow up. ECOG PS and stage\u0000were found statistically significant risk factors in model created to determine overall survival.Conclusion:Performance score at the time of diagnosis, stage and presence of liver metastasis are identified as prognostic factors for SCLC and of these factors are\u0000quite valuable to predict the clinical outcome.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91353354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aerobic exercise training modulates bone mineralstatus in patients with chronic obstructive pulmonarydisease 有氧运动训练调节慢性阻塞性肺疾病患者的骨矿物质状态
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81906
S. El-Kader, O. Al-Jiffri, Hussein O. Al-Jiffri
{"title":"Aerobic exercise training modulates bone mineralstatus in patients with chronic obstructive pulmonarydisease","authors":"S. El-Kader, O. Al-Jiffri, Hussein O. Al-Jiffri","doi":"10.29333/EJGM/81906","DOIUrl":"https://doi.org/10.29333/EJGM/81906","url":null,"abstract":"Background:Chronic obstructive pulmonary disease (COPD) appears to be associated with low bone mineral density (BMD) due to long-term use of corticosteroids as a\u0000result patients with COPD are at risk for osteoporosis-related fractures and worsening pulmonary function.Objective:The present study aimed to measure the effects of treadmill walking exercises on bone mineral status in patients with COPD.Methods:Sixty patients with moderate COPD of both sexes, their age ranged from 45 to 58 years. Subjects were divided into two equal groups: training group (group\u0000A) received aerobic exercise training on treadmill for six months, where the second group (B) was considered as a control group who received no exercise training. The\u0000program consisted of three sessions per week for six months.Results:The results of this study indicated a significant increase in BMD of the lumbar spine & the radius and serum calcium & significant reduction in parathyroid\u0000hormone in group (A), while these changes were not significant in group (B).Also; there was a significant difference between both groups at the end of the study.Conclusion:Treadmill walking exercise training is an effective treatment policy to improve bone mineral status in patients with COPD.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83275899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Isolated omental panniculitis: two case reports and review of literature 孤立性大网膜炎:2例报告及文献复习
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81894
Sukru Tas, O. Cıkman, A. Ozdil, Y. Akgun, M. Karaayvaz
{"title":"Isolated omental panniculitis: two case reports and review of literature","authors":"Sukru Tas, O. Cıkman, A. Ozdil, Y. Akgun, M. Karaayvaz","doi":"10.29333/EJGM/81894","DOIUrl":"https://doi.org/10.29333/EJGM/81894","url":null,"abstract":"Isolated omental panniculitis (IOP), a rare form of acute abdominal syndrome, is defined as intraabdominal panniculitis that involves only omentum without extraabdominal fat necrosis, inflammatory bowel disease and pancreatitis. In the search made using PubMed English database, only 4 cases are determined with IOP. IOP is conceptually confused with idiopathic omental infarction (IOI). However, omental infarctions that are rare causes of acute abdominal syndromes were published by Bush for the first time in 1986 and less than 400 cases were reported. In this article we aimed to publish 2 IOP patients who applied with acute abdominal manifestation and were treated with laparoscopic omental resection to discuss the other 4 IOP cases comparing with IOP together with literature.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81714850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Inflammatory Biomarkers And Endothelial Dysfunction Among Obese Type 2 Diabetic Patients: A Correlational Study 肥胖2型糖尿病患者的炎症生物标志物和内皮功能障碍:一项相关研究
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81901
M. S. Al-dahr
{"title":"Inflammatory Biomarkers And Endothelial Dysfunction Among Obese Type 2 Diabetic Patients: A Correlational Study","authors":"M. S. Al-dahr","doi":"10.29333/EJGM/81901","DOIUrl":"https://doi.org/10.29333/EJGM/81901","url":null,"abstract":"Background:The vascular complications of diabetes mellitus impose a huge burden on the management of this disease. Inflammation is one of the major factors in the\u0000formation of endothelial dysfunction. Endothelial dysfunction is a major contributor to the complications of diabetes mellitus.Objective:The aim of the present study was to investigate the possible relationship between inflammation and endothelial dysfunction in obese type 2 diabetic\u0000patients.Material and Methods:Forty obese type 2 diabetic patients (24 males and 16 females) with body mass index (BMI) ranged from 31 to 35 Kg/m2, non-smokers, free\u0000from respiratory, kidney; liver, metabolic and neurological disorders were recorded in this study. Their age ranged from 40 to 55 years were included in this study as\u0000the first group (A). While a forty non-diabetic subjects (23 males and 17 females) not suffering of any disease, their age ranged from 40 to 52 years were included in\u0000this study as the second group (B) and considered as a control group.Results:Diabetic patients showed significantly higher values of TNF-α, IL-6, CRP, HBA1c, ICAM-1, VCAM-1 and E-selectin in comparison to controls. Also, there was\u0000significant positive correlation between inflammatory and endothelial dysfunction biomarkers among obese diabetic patients.Conclusions:There was a strong association between elevated biomarkers of inflammation and endothelial dysfunction among type 2 diabetic patients.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85978896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Robotic training on walking and balance inpatient with Hereditary Spastic Paraplegia 机器人训练对遗传性痉挛性截瘫患者行走及平衡能力的影响
European journal of general medicine Pub Date : 2018-01-06 DOI: 10.29333/EJGM/81909
I. Boyraz, Bunyamin Koc, Hakan Sarman, M. Ozdemir
{"title":"Effect of Robotic training on walking and balance inpatient with Hereditary Spastic Paraplegia","authors":"I. Boyraz, Bunyamin Koc, Hakan Sarman, M. Ozdemir","doi":"10.29333/EJGM/81909","DOIUrl":"https://doi.org/10.29333/EJGM/81909","url":null,"abstract":"Our patient was 22 years old and was being followed with pure Hereditary Spastic Paraplegia. He was provided with robot assisted-gait training combined with\u0000physiotherapy. Robot-assisted gait training lasted 40 minutes per a day and 20 sessions training. enforced about 7 weeks and three times in a week. Strenghten,\u0000stretching and balance exercise were applied as physiotherapy every day. He was evealuated in terms of functional ambulation category, Medical Research Council\u0000(MRC) Scale for muscle strength, Modified Ashworth Scale (MAS), 6-minute walking test, 10-meter walking test, timed up and go, Berg Balance Scale before and after\u0000treatment.After the treatments, the patient could walk more confidently and speedy. Robotic training can contribute to physiotherapy as plus to improve patient\u0000walking and balance.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80836400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies on Asymptomatic Bacteriuria in Diabetic Individuals from Rural Area 农村糖尿病患者无症状菌尿的研究
European journal of general medicine Pub Date : 2018-01-04 DOI: 10.29333/EJGM/81765
M. Rastogi, M. Davane, B. Nagoba
{"title":"Studies on Asymptomatic Bacteriuria in Diabetic Individuals from Rural Area","authors":"M. Rastogi, M. Davane, B. Nagoba","doi":"10.29333/EJGM/81765","DOIUrl":"https://doi.org/10.29333/EJGM/81765","url":null,"abstract":"","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80902257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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