European Journal of Dermatology最新文献_第4页

Successful treatment of severe Mycobacterium marinum infection in the right hand: a case of cutaneous necrosis with osteomyelitis following sea bass cultivation. 右手严重海洋分枝杆菌感染的成功治疗：黑鲈养殖后皮肤坏死伴骨髓炎1例。

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4882

Yun Xiang, Xiaoxi Xu, Suxiang Lin, Xingshi Zhang, Lingling Ma, Dan Hu, Yuping Ran

引用次数: 0

Classic Hodgkin lymphoma in a patient treated with ixekizumab for generalized pustular psoriasis. 经典霍奇金淋巴瘤患者接受ixekizumab治疗广泛性脓疱性牛皮癣。

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4877

Erina Taniguchi, Mika Yamanaka-Takaichi, Tomoko Oshimo, Yasuhiro Nakashima, Daisuke Tsuruta

引用次数: 0

Differences in the management of toxic epidermal necrolysis related and unrelated to immune checkpoint inhibitors. 与免疫检查点抑制剂相关和无关的中毒性表皮坏死松解治疗差异

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4915

Fumika Minakawa, Nozomi Yanagida, Seiko Sugiyama, Yoichiro Toi, Yosuke Urakami, Daigo Oka, Ryo Tanaka, Takenobu Yamamoto, Yumi Aoyama

{"title":"Differences in the management of toxic epidermal necrolysis related and unrelated to immune checkpoint inhibitors.","authors":"Fumika Minakawa, Nozomi Yanagida, Seiko Sugiyama, Yoichiro Toi, Yosuke Urakami, Daigo Oka, Ryo Tanaka, Takenobu Yamamoto, Yumi Aoyama","doi":"10.1684/ejd.2025.4915","DOIUrl":"https://doi.org/10.1684/ejd.2025.4915","url":null,"abstract":"There are currently no reliable biomarkers to predict the occurrence of severe complications and treatment response in patients with toxic epidermal necrolysis (TEN). Immune checkpoint inhibitor-related TEN (irTEN) is much rarer than typical TEN, but mortality rates associated with irTEN are much higher than those for TEN. TEN and irTEN should therefore be managed in a different manner. To investigate biomarkers that could be used to predict outcomes and therapeutic efficacy associated with irTEN and TEN. Seven patients with TEN and two patients with irTEN were included in the study. The seven patients with TEN were treated with varying combinations and sequences of high-dose corticosteroids, intravenous immunoglobulin, pulse corticosteroids and plasma pheresis. Four of the seven TEN patients developed severe complications, and one patient eventually died due to cytomegalovirus disease. We found that, for TEN, a high neutrophil-to-lymphocyte ratio (NLR) at baseline was associated later onset of severe complications, and a subsequent decrease in NLR after starting immunosuppressive therapy was associated with a beneficial treatment response. In contrast, the opposite was found for the two irTEN patients; a low NLR at baseline and an increase in NLR after starting treatment were associated with poor outcome and a beneficial treatment response, respectively. The NLR may be differentially used as a practical and cost-efficient biomarker to predict treatment response and disease outcomes in patients with TEN and irTEN.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 3","pages":"224-229"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hidradenitis suppurativa: a multidisciplinary challenge! 化脓性汗腺炎：多学科挑战！

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4857

Axel Villani

引用次数: 0

Response to bimekizumab in a patient with generalized pustular psoriasis who developed secondary failure. 比美珠单抗对继发失败的广泛性脓疱性银屑病患者的疗效。

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4886

Yusuke Muto, Mai Ueki, Yoshihide Asano

引用次数: 0

A case of solitary scabietic lymphocytic vasculitis on the glans: insights into lymphocyte-related aetiology. 龟头孤立性疥疮性淋巴细胞性血管炎1例：淋巴细胞相关病因分析。

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4891

Takuya Nagata, Yasuaki Ikuno, Yasuhiro Maeda, Akihiko Yamaguchi, Toshifumi Takahashi, Akiko Arakawa, Noriki Fujimoto

引用次数: 0

Systemic viral exanthem (hand-foot-and-mouth disease) induced by coxsackievirus A6 in an elderly adult. 1例老年人由柯萨奇病毒A6引起的全身病毒渗漏（手足口病）。

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4892

Sunyoung Park, Kyoko Tsuruta, Kazumitsu Sugiura

引用次数: 0

Sunscreen products: little-known cosmetic counterfeits. 防晒产品：鲜为人知的假冒化妆品。

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4902

Céline Couteau, Simon Catroux, Coralie Le Roy, Julien Gauvrit, Gaétane Wielgosz-Collin, Eva Paparis, Laurence Coiffard

引用次数: 0

Eosinophilic granulomatosis with polyangiitis and facial swelling. 嗜酸性肉芽肿伴多血管炎和面部肿胀。

IF 1.5 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4878

Jie Ren, Huiping Wang, Suju Luo

引用次数: 0

Improving the patient care pathway and multidisciplinary management are major challenges in Hidradenitis suppurativa treatment. 改善患者护理途径和多学科管理是化脓性汗腺炎治疗的主要挑战。

IF 2 4区医学

European Journal of Dermatology Pub Date : 2025-06-01 DOI: 10.1684/ejd.2025.4859

Ziad Reguiaï

{"title":"Improving the patient care pathway and multidisciplinary management are major challenges in Hidradenitis suppurativa treatment.","authors":"Ziad Reguiaï","doi":"10.1684/ejd.2025.4859","DOIUrl":"https://doi.org/10.1684/ejd.2025.4859","url":null,"abstract":"Hidradenitis suppurativa (HS) is a chronic inflammatory disease resulting from the close interplay between genetic predisposition, dysregulation of the mechanisms involved in autoinflammatory pathways, dysfunctional response to bacterial biofilm changes, and environmental factors that potentially exacerbate the disease. Its cutaneous manifestations may represent just the tip of the iceberg, as numerous comorbidities may be associated with the disease. The risk of occurrence of inflammatory bowel disease is three times higher than that in the general population. At least 5% of patients also have spondylarthritis, and the risk of cardiovascular events and death from myocardial infarction is significantly increased. Psychiatric co-morbidities, ranging from severe anxiety to depression and suicidal risk, also contribute greatly to the disease burden. The painful and chronic nature of the flares and the highly conspicuous appearance of HS lesions, whether inflammatory or permanent scarring, can lead to social isolation and addiction, particularly to analgesics. Despite its high frequency, easy diagnosis, severe impact on patients' daily lives, and the discovery of new treatments, many patients still experience prolonged diagnostic delays, therapeutic inertia, and chaotic, inappropriate management. For HS and the prevention of associated major complications, the identification of the points of rupture in its management, an improved care pathway and a multidisciplinary therapeutic approach are a societal concern and a major public health challenge.","PeriodicalId":11968,"journal":{"name":"European Journal of Dermatology","volume":"35 S1","pages":"8-13"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0