European Journal of Integrative Medicine最新文献

{"title":"Client experiences and perceptions of naturopathic treatment in New Zealand: A qualitative study","authors":"Asmita Patel,&nbsp;Robyn Carruthers,&nbsp;Karen Wesseling,&nbsp;Karen Mees,&nbsp;Wayne Hill","doi":"10.1016/j.eujim.2024.102390","DOIUrl":"10.1016/j.eujim.2024.102390","url":null,"abstract":"<div><h3>Introduction</h3><p>Naturopathy is a well-known and utilised form of traditional, complementary, and integrative medicine (TCIM). Limited New Zealand research exists that has examined the utilisation of naturopathy from the perspective of users. The present study was designed to identify and explore individual's experiences and perceptions of naturopathic care.</p></div><div><h3>Methods</h3><p>Twenty clients (18 female and two male) who attended a student naturopathy and herbal medicine teaching clinic in Auckland, New Zealand were individually interviewed via Zoom video conferencing using open-ended questions. Interview transcripts were anlysed using an inductive thematic approach, focusing on similarities in participants' experiences and perceptions of their naturopathic treatment.</p></div><div><h3>Results</h3><p>Six main themes were identified regarding individual's experiences and perceptions of naturopathic care (1) feeling heard, (2) perceived attributes of the student practitioner and feeling looked after, (3) perceived knowledge of student practitioners, (4) high degree of client education, (5) partnership, empowerment and ownership, and (6) recommending naturopathy based on own experiences.</p></div><div><h3>Conclusions</h3><p>Participants reported positive experiences and perceptions of their naturopathic treatment. Participants felt heard and looked after and indicated that their student naturopaths were caring, supportive and knowledgeable. Client education enhanced health literacy and participants felt empowered and in control of their health and healing. Client education was perceived to be important for individuals with chronic health conditions, as the information imparted was not always covered by their other healthcare practitioners.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"70 ","pages":"Article 102390"},"PeriodicalIF":1.9,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141841627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting the relationship between traditional East Asian medicine and biomedicine: Incorporating the Western into the Eastern","authors":"András Béres","doi":"10.1016/j.eujim.2024.102388","DOIUrl":"10.1016/j.eujim.2024.102388","url":null,"abstract":"<div><h3>Introduction</h3><p>Whether traditional East Asian medicine (TEAM) is compatible with biomedicine remains controversial, with biomedicine research failing to explain key TEAM concepts. This article hypothesizes that reconciliation could be effective if biomedicine assumed that it examines a limited portion of reality, whereas Eastern medicine aims to conceptualize reality in its entirety. <em>Re</em>-discovering elements of Western thought that allow epistemological expansion, such as the notion of a non-material aspect inherent to all phenomena, and its implications for research methodology, can encourage biomedical research to reflect on TEAM.</p></div><div><h3>Approach</h3><p>The article reviews sources from the Western and Eastern medical literature to explore the above hypothesis.</p></div><div><h3>Discussion</h3><p>The concept of Qi (氣), inherent in TEAM's interpretive framework, lays the foundations for theoretical compatibility and a practical integrative approach. In TEAM, Qi is the basic fabric from which all things are made; however, holding that all things have a non-material aspect is also deeply rooted in the European religious and philosophical tradition. This article proposes that biomedicine detects the denser part of the Qi spectrum conceived by TEAM. As an illness progresses, parts of Qi that make up the organism become increasingly separated, but biomedicine detects disharmony only when the magnitude reaches a certain level owing to its sensitivity range.</p></div><div><h3>Conclusion</h3><p>Both TEAM and biomedicine consider the patient's complaint as an unquestionable reality that medicine can observe and aims to alleviate. TEAM assumes that traditions distilled over millennia require verification through evidence-based medicine to gain credibility in the West, which owes its success to its skeptical attitude. Meanwhile, biomedicine assumes that some mechanisms that influence health and healing may not be measurable by current biomedical devices. However, this does not mean that these mechanisms cannot be verified, albeit with an emphasis on patients’ subjective experiences. The theoretical compatibility of TEAM and biomedicine creates sufficient legitimacy for their co-existence, and research on their sequential, rather than alternative or complementary, use in healthcare is needed.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"70 ","pages":"Article 102388"},"PeriodicalIF":1.9,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S187638202400057X/pdfft?md5=b7f8e268515f241535915f60e34146d8&pid=1-s2.0-S187638202400057X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of different acupuncture therapies for dry eye disease: A systematic review and network meta-analysis","authors":"Qingyuan Zhang ,&nbsp;Shenghe Huang ,&nbsp;Qianyan Wu ,&nbsp;Jingwen Zhang ,&nbsp;Yao Xiao ,&nbsp;Shuailiang Huang ,&nbsp;Xiaogang Xu ,&nbsp;Delin Zhang","doi":"10.1016/j.eujim.2024.102387","DOIUrl":"10.1016/j.eujim.2024.102387","url":null,"abstract":"<div><h3>Introduction</h3><p>Dry eye disease (DED) has become increasingly prevalent in ophthalmology, significantly impacting patients' quality of life. Despite the widespread use of acupuncture therapies in treating DED, the most effective acupuncture treatment strategy remains uncertain. This study aimed to provide guidance in clinical practice for selecting the most effective acupuncture treatment strategy using the network meta-analysis (NMA) method.</p></div><div><h3>Methods</h3><p>Seven English and Chinese databases were searched from their inception to October 15, 2023, to collect randomized controlled trials (RCTs) related to acupuncture therapies for treating DED. The risk of bias was assessed using the revised Cochrane risk of bias tool (ROB 2.0). Network meta-analysis was conducted using R 4.1.2 and Stata 17.0. The Confidence in Network Meta-Analysis (CINeMA) tool was used to evaluate the certainty of evidence.</p></div><div><h3>Results</h3><p>A total of 41 studies with 2931 participants were included. The network meta-analysis results showed that conventional acupuncture combined with thumbtack needle had the best efficacy in improving tear break-up time (TBUT) (MD = 2.95, 95 % CI [1.49, 4.39]) and Schirmer's test (MD = 3.34, 95 % CI [0.90, 5.79]). In terms of improving the corneal fluorescein staining score, conventional acupuncture combined with electroacupuncture demonstrated the best efficacy (SMD = -0.80, 95 % CI [-1.40, -0.18]). The confidence ratings of different treatment comparisons were judged as very low to low. Eight studies reported adverse effects, none of which were serious.</p></div><div><h3>Conclusion</h3><p>The NMA results support the use of acupuncture for treating DED. Among the therapies, conventional acupuncture combined with thumbtack needle and conventional acupuncture combined with electroacupuncture have higher priority. However, before widespread adoption, more multicenter, randomized, double-blind, and placebo-controlled clinical trials are needed to confirm these findings.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"70 ","pages":"Article 102387"},"PeriodicalIF":1.9,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disease Evolution-based Specificity Target Discovery (DESTD) by analyzing Jiawei-Maxing-Shigan Decoctions against COVID-19","authors":"Beiyan Li,&nbsp;Chaoqun Liu,&nbsp;Zhan Shu,&nbsp;Shijie Bi,&nbsp;Yue Ren,&nbsp;Kaiyang Liu,&nbsp;Anlei Yuan,&nbsp;Lulu Zheng,&nbsp;Zhenzhen Xu,&nbsp;Zewen Wang,&nbsp;Yanling Zhang","doi":"10.1016/j.eujim.2024.102386","DOIUrl":"10.1016/j.eujim.2024.102386","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;p&gt;Diverse disease courses, each corresponding to a unique pathophysiological mechanism, characterize the coronavirus 2019 disease (COVID-19). Intensive research on discovering specificity targets for treating COVID-19 has significant implications for understanding pathogenesis mechanisms in disease evolution. Traditional Chinese medicine (TCM) has shown distinctive advantages in treating COVID-19 in different periods, which may provide new clues for target discovery. In order to accomplish the goal of providing a Disease Evolution-based Specificity Target Discovery (DESTD), the purpose of this paper was to conduct an analysis of the difference in target weighted value during each cycle of COVID-19.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Our study employed a comprehensive methodology combining TCM pharmacology with modern biological techniques. Three Jiawei-Maxing-Shigan Decoctions (MS Decoction), were selected as samples, including Hanshi-Yufei decoction (HY Decoction), Shidu-Yufei decoction (SY Decoction), and Yidu-Bifei decoction (YB Decoction). The core components of these decoctions are the same, while the differences correspond to different periods of COVID-19. The DESTD approach consists of several parts: network pharmacology analysis to identify potential targets, molecular docking simulation to investigate TCM components acting on potential targets, and biological validation. This study employed several cell line models, including RAW264.7 (Mouse Mononuclear Macrophages Cells), 16HBE (Human Bronchial Epithelial Cells), and HUVEC&lt;img&gt;C (Human Umbilical Vein Endothelial Cells), to explore new approaches for key target discovery.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;During the mild phase of COVID-19, HY Decoction exhibited anti-inflammatory effects by specifically down-regulating the expression of heat shock protein HSP 90-alpha (&lt;em&gt;HSP90AA1&lt;/em&gt;), transcription factor JUN (&lt;em&gt;JUN&lt;/em&gt;) and other five genes in RAW264.7. In the common phrase, inflammation and fibrosis could be specifically alleviated by down-regulating the expression of interleukin-10 (&lt;em&gt;IL10&lt;/em&gt;) and mitogen-activated protein kinase 14 (&lt;em&gt;MAPK14&lt;/em&gt;) by SY Decoction respectively acting on RAW264.7 and 16HBE cell lines. In severe cases, YB Decoction specifically down-regulated the expression of prostaglandin endoperoxide synthase-2 (&lt;em&gt;PTGS2&lt;/em&gt;), caspase-3 (&lt;em&gt;CASP3&lt;/em&gt;), and three other genes to protect vascular endothelial cells from oxidative damage. Moreover, YB also played a role in anti-fibrosis by specifically down-regulating the expression of estrogen receptor beta (&lt;em&gt;ESR2&lt;/em&gt;), vascular cell adhesion protein 1 (&lt;em&gt;VCAM1&lt;/em&gt;), and other three genes, and up-regulating the expression of prostaglandin endoperoxide synthase-1 (&lt;em&gt;PTGS1&lt;/em&gt;) in the severe period. These targeted actions align with a holistic treatment approach and provide tailored therapies for different stages of COVID-19.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;p&gt;This resear","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"70 ","pages":"Article 102386"},"PeriodicalIF":1.9,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141701077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of herbal medicine in patients with inflammatory bowel disorders in Iran: A cross-sectional study","authors":"Ebrahim Shamsaddini ,&nbsp;Fatemeh Sadat Hasheminasab ,&nbsp;Mahboobeh Raeiszadeh ,&nbsp;Saiedeh Haji-Maghsoudi ,&nbsp;Ahmad Azizian ,&nbsp;Maryam Azimi","doi":"10.1016/j.eujim.2024.102384","DOIUrl":"10.1016/j.eujim.2024.102384","url":null,"abstract":"<div><h3>Introduction</h3><div>The use of complementary and alternative medicine, particularly herbal medicine, is increasing, especially in chronic disorders. This study aims to identify common herbal medicines used by patients with inflammatory bowel disease, and to investigate their relationship with the quality of life, disease severity, and levels of anxiety, stress, and depression experienced by these patients.</div></div><div><h3>Methods</h3><div>A total of 104 eligible patients with inflammatory bowel disease and in the middle years of life (20- 60 years old) participated in this cross-sectional study. Data collection was conducted using various assessment tools, i.e. a self-administered ethnomedicine questionnaire, Partial Mayo scoring index assessment, Crohn's disease activity index, Quality of Life Questionnaire, and Depression, Anxiety and Stress Scale.</div></div><div><h3>Results</h3><div>The findings of the present study revealed that 61.5% of the patients surveyed commonly used herbal medicine to alleviate their symptoms in the past year. Among the various herbs, <em>Matricaria chamomilla</em> L<em>., Zataria multiflora</em> Boiss., and <em>Mentha Spicata</em> L. were found to be most commonly used. Furthermore, a significant association was identified between herbal medicine use and age, Body Mass Index, marital status, level of education, alcohol consumption, Quality of Life, and severity disorder scores of the patients.</div></div><div><h3>Conclusion</h3><div>Our results suggested a significant association between herbal medicine use and lower severity disorder scores and higher quality of life in patients with inflammatory bowel disease. However, these findings may not be generalizable to all patients with inflammatory bowel disease, or to patients in other geographical regions.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"71 ","pages":"Article 102384"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of infantile tuina for improving motor dysfunction in children with spastic cerebral palsy: A systematic review and meta-analysis of randomized controlled trials","authors":"Zicheng Wei ,&nbsp;Zhen Liu ,&nbsp;Hongjiao Wu ,&nbsp;Kaizheng Wang ,&nbsp;Shuang Wu ,&nbsp;Lijiang Lv ,&nbsp;Zhizhen Lv","doi":"10.1016/j.eujim.2024.102382","DOIUrl":"10.1016/j.eujim.2024.102382","url":null,"abstract":"<div><h3>Introduction</h3><p>Infantile cerebral palsy (ICP) is a disease that causes cognitive and motor dysfunction in children, severely affecting their growth and mental health. Infantile tuina is a prominent treatment modality in traditional Chinese medicine (TCM). However, the effectiveness of infantile tuina remains uncertain. This systematic review aimed to assess the efficacy of infantile tuina in enhancing motor dysfunction in ICP through randomized controlled trials (RCTs).</p></div><div><h3>Methods</h3><p>We completed the meta-analysis according to the PRISMA 2020 checklist. Randomized controlled trials (RCTs) were searched for in seven databases including Medline, Ovid EMBASE, Cochrane Library, Web of Science, China national knowledge infrastructure, Chinese biomedical literature, and Wan Fang from the establishment of the database until November 7, 2023. The effectiveness of infantile tuina to treat motor dysfunction in children with spastic cerebral palsy was evaluated using outcome indexes such as effective rate, Gross motor function measure (GMFM), Modified Ashworth Scale (MAS), and ankle passive dorsiflexion angle.</p></div><div><h3>Results</h3><p>A total of 12 RCTs were included in this systematic review, which included 950 patients. Meta-analysis of the results indicated that infantile tuina combined with conventional rehabilitation treatment for ICP produced better results than conventional rehabilitation treatment alone. The experimental group intervention had a significant effect on the improvement of ICP treatment efficiency [Relative Risk (RR) = 1.21; 95% Confidence Interval (CI) = 1.10, 1.33], GMFM [MD = 4.76, 95% CI = 3.23, 3.29], MAS [Mean difference (MD) = -0.83, 95% CI = -1.02, -0.64], and ankle dorsiflexion angle [MD = -4.82, 95% CI = -7.45, -2.18]. The results were statistically significant (<em>P</em> &lt; 0.05).</p></div><div><h3>Conclusions</h3><p>As a complementary therapy to conventional rehabilitation therapy, infantile tuina produced significant improvements in ICP treatment effectiveness in this systematic review. The main limitation in the evidence was a lack of high-quality studies and many studies had small sample sizes.</p></div><div><h3>Registration</h3><p>PROSPERO ID: CRD42023446889.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102382"},"PeriodicalIF":1.9,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the role of miR-26b-5p and PTGS2 in schizophrenia treatment using Wendan decoction: Network pharmacology and experimental validation","authors":"Yilin Liu ,&nbsp;Xinling Zhao ,&nbsp;Qing Long ,&nbsp;Zeyi Guo ,&nbsp;Xiang Cao ,&nbsp;Xiaoqin Wu ,&nbsp;Fangjun Tu ,&nbsp;Yunqiao Zhang ,&nbsp;Xu You ,&nbsp;Xiuying Shi ,&nbsp;Zhaowei Teng ,&nbsp;Yong Zeng","doi":"10.1016/j.eujim.2024.102380","DOIUrl":"https://doi.org/10.1016/j.eujim.2024.102380","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aimed to identify the target of action of Wendan decoction, a classical Chinese herbal formula used for the treatment of psychiatric disorders, specifically schizophrenia, using network pharmacology.</p></div><div><h3>Methods</h3><p>Traditional Chinese Medicine (TCM) bioinformatics and network pharmacology were employed to predict the genes regulated by miR-26b-5p and identify the active ingredients and related targets of the Wendan decoction from public databases. Key components and targets were screened by constructing a \"TCM-component-target\" network, followed by pathway enrichment analysis of the related targets. The expression levels of miR-26b-5p and prostaglandin-endoperoxide synthase 2 (<em>PTGS2</em>) in the peripheral blood of patients with schizophrenia patients and healthy individuals were determined using RT-qPCR. Molecular docking was performed to explore the interaction between the active ingredients of the Wendan decoction and key differentially expressed molecules, investigating the role of miR-26b-5p in the treatment of schizophrenia with the Wendan decoction.</p></div><div><h3>Results</h3><p>A total of 135 active constituents were extracted from the Wendan decoction, and 144 molecules, including <em>PTGS2</em> and other derivatives, were screened for drug-target and disease-target inter-mapping. Compared to peripheral blood samples from healthy controls and patients with depression, peripheral blood samples from patients with schizophrenia patients showed low miR-26b-5p expression and elevated <em>PTGS2</em> expression, with no significant difference observed in the expression between healthy controls and patients with depression. Molecular docking revealed that several active compounds were found in five of the six constituents of the Wendan decoction bound with <em>PTGS2</em>. Pathway enrichment analysis suggested that the Wendan decoction may have a potential therapeutic role in treating schizophrenia by regulating the circadian rhythm, N-methyl-<span>d</span>-aspartate glutamate receptor activity, inflammatory mediator regulation of transient receptor potential channels, and other pathways implicated in schizophrenia.</p></div><div><h3>Conclusion</h3><p>Wendan decoction may treat schizophrenia via the miR-26b-5p targeting factor <em>PTGS2</em> and inflammation-related pathways. miR-26b-5p, combined with <em>PTSG2</em>, holds the potential as a differential diagnostic marker for schizophrenia.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102380"},"PeriodicalIF":1.9,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876382024000507/pdfft?md5=6707e483381a1edde4202904de19904d&pid=1-s2.0-S1876382024000507-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the use of colored Trace Images in Kids' Books with passive distractions to decrease pain and fear during cannulation in children: A randomized clinical trial","authors":"Sherzad Khudeida Suleman ,&nbsp;Nizar BakirYahya ,&nbsp;Stefan Nilsson ,&nbsp;Karin Enskär","doi":"10.1016/j.eujim.2024.102379","DOIUrl":"https://doi.org/10.1016/j.eujim.2024.102379","url":null,"abstract":"<div><h3>Introduction</h3><p>Cannulation can be frightening and a source of pain and fear for pediatric patients. The study evaluated the effectiveness of Trace Image and Coloring for Kids-Book (TICK-B) as active distraction with two passive distractions in reducing children's pain and fear during cannulation.</p></div><div><h3>Methods</h3><p>This study employed a prospective, controlled, randomized experiment conducted from January 2023 to April 2023 at Heevi Pediatric hospital in the Kurdistan region of Iraq. A total of 176 participants were randomly assigned in to one of four study groups, with 44 participants assigned to each group. The interventions were administered 2–3 min before continued until the cannulation procedure finished. Data were collected through interviews conducted before and after the procedure. Children reported pain using Wong-Baker FACES® scale, and fear evaluated with the Child Fear Scale as an outcome after the cannulation procedure. Children's outcomes during and after procedure were measured 2–3 min after completed procedure.</p></div><div><h3>Results</h3><p>All distraction methods significantly reduced children's pain and fear compared to the control group. TICK-B showed large effects in reducing average pain (mean difference = -4.65, 95 % CI: -5.67 to -3.65) and fear (mean difference = -2.18, 95 % CI: -2.67 to -1.69) during cannulation. Post-procedure, TICK-B maintained large pain relief (mean difference = -4.10, 95 % CI: -4.98 to -3.22) and fear reduction (mean difference = -1.89, 95 % CI: -2.39 to -1.39) effects. Music listening and cartoon watching both showed improvements compared to the control group, with minimal differences between them in terms of pain and fear during the procedure. Also, the differences were the same after the procedure. No adverse events were reported.</p></div><div><h3>Conclusion</h3><p>All distraction techniques effectively and safely decreased children's pain and fear during cannulation. The TICK-B technique most effectively reduced children's pain and fear during cannulation procedures compared to music-listening and cartoon-watching techniques.</p></div><div><h3>Trial registration</h3><p>NCT04977323.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102379"},"PeriodicalIF":1.9,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876382024000490/pdfft?md5=cfe245189763eea4e01a73c061bb2c99&pid=1-s2.0-S1876382024000490-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141606543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol for the reporting assessment of clinical trials with non-pharmacological therapies in Chinese medicine","authors":"Hanzhi Tan ,&nbsp;Nana Wang ,&nbsp;Han Li ,&nbsp;Chung Wah Cheng ,&nbsp;Yalin Jiao ,&nbsp;Dongni Shi ,&nbsp;Juan Wang ,&nbsp;Jiashuai Deng ,&nbsp;Ji Li ,&nbsp;Fei Han ,&nbsp;Ping Wang ,&nbsp;Zhaoxiang Bian ,&nbsp;Xuan Zhang","doi":"10.1016/j.eujim.2024.102381","DOIUrl":"https://doi.org/10.1016/j.eujim.2024.102381","url":null,"abstract":"<div><h3>Introduction</h3><p>Non-pharmacological treatment in Chinese Medicine (NPTCM) plays a crucial and distinct role in clinical practice, and increasingly within randomized controlled trials (RCTs). With the successive publication of Consolidated Standards Of Reporting Trials (CONSORT) extensions for acupuncture, moxibustion, cupping, and Tuina/massage, this study aims to assess the reporting characteristics and quality of published RCTs based on these specific reporting checklists.</p></div><div><h3>Methods</h3><p>Databases including All EBM Reviews, AMED, Embase, Ovid MEDLINE(R), CNKI, VIP Chinese Medical Journal Database, and Wanfang Data will be searched, with the publication date limited to January 1, 2022 to December 31, 2022. The interventions of interest are RCTs involving acupuncture, moxibustion, cupping or Tuina/massage, with language restricted to Chinese or English. Two reviewers will conduct the screening process with double-checking by the third reviewer. The purpose of data extraction is to summarize the study designs and implementation characteristics of these four types of interventions, and a pre-designed data extraction form will be utilized. For quality assessment, a standard operating procedure (SOP) will be developed, using an assessment form based on the checklist items of the four CONSORT extensions. Each article will be reviewed by two reviewers in a paired back-to-back manner, and Cohen's kappa statistic will be calculated to assess inter-rater agreement. Descriptive statistics will be used to present the quality of reporting. Subgroup comparisons will be conducted regarding different types of interventions, locations and publication languages.</p></div><div><h3>Discussion</h3><p>This study aims to identify and assess the current reporting characteristics and quality of the above four types of NPTCM interventional trials. Based on the results, it is hoped to provide suggestions for future application or promotion of the CONSORT extensions for NPTCM.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102381"},"PeriodicalIF":1.9,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876382024000519/pdfft?md5=8866f83e65c4f29c875c6be8434107ea&pid=1-s2.0-S1876382024000519-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141539417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of acupuncture in the treatment of osteoporosis-related fractures: A systematic review and Bayesian network meta-analysis","authors":"Ruya Sheng ,&nbsp;Mingxia Wu ,&nbsp;Yali Qiu ,&nbsp;Qing Sun","doi":"10.1016/j.eujim.2024.102378","DOIUrl":"https://doi.org/10.1016/j.eujim.2024.102378","url":null,"abstract":"<div><h3>Introduction</h3><p>In recent years, there has been an increasing interest in the utilization of different acupuncture regimens as alternative therapies for fractures linked to osteoporosis. Nevertheless, the efficacy of these diverse treatment choices continues to be a subject of contention. To tackle this matter, a comprehensive Bayesian network meta-analysis has been undertaken to thoroughly assess the potential advantages of various acupuncture techniques in the management of osteoporosis-related fractures.</p></div><div><h3>Methods</h3><p>Until April 12, 2023, an extensive search was carried out to identify randomized controlled trials investigating the application of acupuncture in the treatment of fractures related to osteoporosis. The search encompassed multiple databases, such as PubMed, EMBASE, Web of Science, Cochrane Library, China Knowledge Network (CNKI), WanFang, VIP Database, and SinoMed. The network meta-analysis specifically aimed to evaluate the efficacy of different acupuncture techniques in conjunction with conservative biomedical treatment or invasive biomedical surgical treatment for managing fractures related to osteoporosis.</p></div><div><h3>Results</h3><p>A total of 35 articles were included, involving 2,727 patients. These articles examined and investigated five different types of acupuncture treatment options. The evaluated acupuncture treatments included ordinary acupuncture, electroacupuncture, floating acupuncture, needle-knife, and warm acupuncture. Results showed that when electroacupuncture was combined with daily care, it resulted in a significant decrease in both the Visual Analogue Scale (VAS) score and the Oswestry Disability Index (ODI) score. Specifically, the VAS score decreased by -2.29 (95 % CI: -3.84 ∼ -0.75), while the ODI score decreased by -22.03 (95 % CI: -33.88 ∼ -10.54) compared to those who received only daily care. Additionally, there was a significant decrease in the VAS score when comparing the combination of ordinary acupuncture with percutaneous vertebroplasty (PVP) surgery to PVP surgery alone. The VAS score decreased by -1.39 (95 % CI: -2.73 ∼ -0.04) in the group that underwent both acupuncture and surgery. Similarly, in the comparison between warm acupuncture combined with percutaneous kyphoplasty (PKP) surgery and PKP surgery alone, there was a significant reduction in the VAS score. The VAS score decreased by -3.62 (95 % CI: -5.49 ∼ -1.74) in the group that received both acupuncture and surgery.</p></div><div><h3>Conclusions</h3><p>The implementation of a well-balanced acupuncture treatment regimen can effectively alleviate pain and disability experienced by patients with fractures related to osteoporosis, irrespective of whether surgical intervention is conducted.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102378"},"PeriodicalIF":1.9,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141539413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}