European Journal of Integrative Medicine最新文献

{"title":"Comparing the use of colored Trace Images in Kids' Books with passive distractions to decrease pain and fear during cannulation in children: A randomized clinical trial","authors":"Sherzad Khudeida Suleman ,&nbsp;Nizar BakirYahya ,&nbsp;Stefan Nilsson ,&nbsp;Karin Enskär","doi":"10.1016/j.eujim.2024.102379","DOIUrl":"https://doi.org/10.1016/j.eujim.2024.102379","url":null,"abstract":"<div><h3>Introduction</h3><p>Cannulation can be frightening and a source of pain and fear for pediatric patients. The study evaluated the effectiveness of Trace Image and Coloring for Kids-Book (TICK-B) as active distraction with two passive distractions in reducing children's pain and fear during cannulation.</p></div><div><h3>Methods</h3><p>This study employed a prospective, controlled, randomized experiment conducted from January 2023 to April 2023 at Heevi Pediatric hospital in the Kurdistan region of Iraq. A total of 176 participants were randomly assigned in to one of four study groups, with 44 participants assigned to each group. The interventions were administered 2–3 min before continued until the cannulation procedure finished. Data were collected through interviews conducted before and after the procedure. Children reported pain using Wong-Baker FACES® scale, and fear evaluated with the Child Fear Scale as an outcome after the cannulation procedure. Children's outcomes during and after procedure were measured 2–3 min after completed procedure.</p></div><div><h3>Results</h3><p>All distraction methods significantly reduced children's pain and fear compared to the control group. TICK-B showed large effects in reducing average pain (mean difference = -4.65, 95 % CI: -5.67 to -3.65) and fear (mean difference = -2.18, 95 % CI: -2.67 to -1.69) during cannulation. Post-procedure, TICK-B maintained large pain relief (mean difference = -4.10, 95 % CI: -4.98 to -3.22) and fear reduction (mean difference = -1.89, 95 % CI: -2.39 to -1.39) effects. Music listening and cartoon watching both showed improvements compared to the control group, with minimal differences between them in terms of pain and fear during the procedure. Also, the differences were the same after the procedure. No adverse events were reported.</p></div><div><h3>Conclusion</h3><p>All distraction techniques effectively and safely decreased children's pain and fear during cannulation. The TICK-B technique most effectively reduced children's pain and fear during cannulation procedures compared to music-listening and cartoon-watching techniques.</p></div><div><h3>Trial registration</h3><p>NCT04977323.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102379"},"PeriodicalIF":1.9,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876382024000490/pdfft?md5=cfe245189763eea4e01a73c061bb2c99&pid=1-s2.0-S1876382024000490-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141606543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol for the reporting assessment of clinical trials with non-pharmacological therapies in Chinese medicine","authors":"Hanzhi Tan ,&nbsp;Nana Wang ,&nbsp;Han Li ,&nbsp;Chung Wah Cheng ,&nbsp;Yalin Jiao ,&nbsp;Dongni Shi ,&nbsp;Juan Wang ,&nbsp;Jiashuai Deng ,&nbsp;Ji Li ,&nbsp;Fei Han ,&nbsp;Ping Wang ,&nbsp;Zhaoxiang Bian ,&nbsp;Xuan Zhang","doi":"10.1016/j.eujim.2024.102381","DOIUrl":"https://doi.org/10.1016/j.eujim.2024.102381","url":null,"abstract":"<div><h3>Introduction</h3><p>Non-pharmacological treatment in Chinese Medicine (NPTCM) plays a crucial and distinct role in clinical practice, and increasingly within randomized controlled trials (RCTs). With the successive publication of Consolidated Standards Of Reporting Trials (CONSORT) extensions for acupuncture, moxibustion, cupping, and Tuina/massage, this study aims to assess the reporting characteristics and quality of published RCTs based on these specific reporting checklists.</p></div><div><h3>Methods</h3><p>Databases including All EBM Reviews, AMED, Embase, Ovid MEDLINE(R), CNKI, VIP Chinese Medical Journal Database, and Wanfang Data will be searched, with the publication date limited to January 1, 2022 to December 31, 2022. The interventions of interest are RCTs involving acupuncture, moxibustion, cupping or Tuina/massage, with language restricted to Chinese or English. Two reviewers will conduct the screening process with double-checking by the third reviewer. The purpose of data extraction is to summarize the study designs and implementation characteristics of these four types of interventions, and a pre-designed data extraction form will be utilized. For quality assessment, a standard operating procedure (SOP) will be developed, using an assessment form based on the checklist items of the four CONSORT extensions. Each article will be reviewed by two reviewers in a paired back-to-back manner, and Cohen's kappa statistic will be calculated to assess inter-rater agreement. Descriptive statistics will be used to present the quality of reporting. Subgroup comparisons will be conducted regarding different types of interventions, locations and publication languages.</p></div><div><h3>Discussion</h3><p>This study aims to identify and assess the current reporting characteristics and quality of the above four types of NPTCM interventional trials. Based on the results, it is hoped to provide suggestions for future application or promotion of the CONSORT extensions for NPTCM.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102381"},"PeriodicalIF":1.9,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876382024000519/pdfft?md5=8866f83e65c4f29c875c6be8434107ea&pid=1-s2.0-S1876382024000519-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141539417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of acupuncture in the treatment of osteoporosis-related fractures: A systematic review and Bayesian network meta-analysis","authors":"Ruya Sheng ,&nbsp;Mingxia Wu ,&nbsp;Yali Qiu ,&nbsp;Qing Sun","doi":"10.1016/j.eujim.2024.102378","DOIUrl":"https://doi.org/10.1016/j.eujim.2024.102378","url":null,"abstract":"<div><h3>Introduction</h3><p>In recent years, there has been an increasing interest in the utilization of different acupuncture regimens as alternative therapies for fractures linked to osteoporosis. Nevertheless, the efficacy of these diverse treatment choices continues to be a subject of contention. To tackle this matter, a comprehensive Bayesian network meta-analysis has been undertaken to thoroughly assess the potential advantages of various acupuncture techniques in the management of osteoporosis-related fractures.</p></div><div><h3>Methods</h3><p>Until April 12, 2023, an extensive search was carried out to identify randomized controlled trials investigating the application of acupuncture in the treatment of fractures related to osteoporosis. The search encompassed multiple databases, such as PubMed, EMBASE, Web of Science, Cochrane Library, China Knowledge Network (CNKI), WanFang, VIP Database, and SinoMed. The network meta-analysis specifically aimed to evaluate the efficacy of different acupuncture techniques in conjunction with conservative biomedical treatment or invasive biomedical surgical treatment for managing fractures related to osteoporosis.</p></div><div><h3>Results</h3><p>A total of 35 articles were included, involving 2,727 patients. These articles examined and investigated five different types of acupuncture treatment options. The evaluated acupuncture treatments included ordinary acupuncture, electroacupuncture, floating acupuncture, needle-knife, and warm acupuncture. Results showed that when electroacupuncture was combined with daily care, it resulted in a significant decrease in both the Visual Analogue Scale (VAS) score and the Oswestry Disability Index (ODI) score. Specifically, the VAS score decreased by -2.29 (95 % CI: -3.84 ∼ -0.75), while the ODI score decreased by -22.03 (95 % CI: -33.88 ∼ -10.54) compared to those who received only daily care. Additionally, there was a significant decrease in the VAS score when comparing the combination of ordinary acupuncture with percutaneous vertebroplasty (PVP) surgery to PVP surgery alone. The VAS score decreased by -1.39 (95 % CI: -2.73 ∼ -0.04) in the group that underwent both acupuncture and surgery. Similarly, in the comparison between warm acupuncture combined with percutaneous kyphoplasty (PKP) surgery and PKP surgery alone, there was a significant reduction in the VAS score. The VAS score decreased by -3.62 (95 % CI: -5.49 ∼ -1.74) in the group that received both acupuncture and surgery.</p></div><div><h3>Conclusions</h3><p>The implementation of a well-balanced acupuncture treatment regimen can effectively alleviate pain and disability experienced by patients with fractures related to osteoporosis, irrespective of whether surgical intervention is conducted.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102378"},"PeriodicalIF":1.9,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141539413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupoint prescriptions, treatment protocol and outcome evidence for acupuncture in diabetic peripheral neuropathy: A scoping review of clinical studies","authors":"Shiqi Ma ,&nbsp;Haipeng Huang ,&nbsp;Fuyu Xue ,&nbsp;Qi Wang ,&nbsp;Shuo Yu ,&nbsp;Qingyu Hou ,&nbsp;Mengyuan Li ,&nbsp;Hongfeng Wang","doi":"10.1016/j.eujim.2024.102376","DOIUrl":"10.1016/j.eujim.2024.102376","url":null,"abstract":"<div><h3>Introduction</h3><p>Acupuncture is a complementary therapy for diabetic peripheral neuropathy (DPN). This scoping review systematically collect clinical studies using acupuncture for the treatment of DPN to analyze and summarize acupuncture point prescriptions, treatment protocols, and outcome indicators regarding clinical trials of acupuncture for DPN. The results will help guide the selection of future clinical protocols.</p></div><div><h3>Methods</h3><p>Eight databases were searched from their inception to March 1, 2023, including PubMed, Excerpt Medica Database (EMBASE), Web of Science, Cochrane Library, Google Scholar, China National Knowledge Infrastructure (CNKI), China Biology Medicine disk (CBM disk), Wan Fang, and Chinese Scientific Journal Database (VIP). Demographic characteristics of study participants, patients, treatment details, acupuncture prescriptions, and outcome indicators were screened and extracted.</p></div><div><h3>Results</h3><p>A total of 219 clinical studies were included, and the number of published studies showed a year-on-year increase. Two hundred eleven studies (96.34%) were conducted in China. One hundred fifty one (68.95%) were conducted in Traditional Chinese Medicine (TCM) hospitals. Two hundred and six (94.06%) studies were randomized controlled trials (RCTs) that treated patients with different clinical symptoms of DPN in 17,945 patients. The primary intervention was manual acupuncture treatment, most commonly with stainless steel needles (φ0.35 mm × 40 mm) left in place for more than 30 minutes. Acupuncture points SP6 and ST36 combined were applied most frequently, and the five points with frequencies over 100 were ST36, SP6, LI11, LI4, and GB34. The outcome indicators of acupuncture for DPN were mainly nerve conduction velocity, effectiveness rating scale, and efficiency. Adverse events were reported in only a few studies and mainly included nausea, pain, and diarrhea.</p></div><div><h3>Conclusions</h3><p>This review provides evidence on treatment protocols, point prescriptions, and outcome metrics for acupuncture for DPN. However, the low quality of the study designs included in the clinical literature resulted in a degree of selection bias in the findings, which still needs to be validated by high-quality clinical trials. Future studies should be designed as more rigorous multicenter, large-sample randomized controlled trials to improve the accuracy and consistency of the effectiveness evaluation of acupuncture for DPN and enrich the standardized clinical treatment protocols for DPN.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"70 ","pages":"Article 102376"},"PeriodicalIF":1.9,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142050204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical profiling and therapeutic potential of Baliospermum montanum: A promising inhibitor of COX-2/15-LOX enzymes and NO production in LPS-stimulated RAW 264.7 macrophages","authors":"Anithakumari Aswathy Krishna ,&nbsp;Beena Levakumar Abhirami ,&nbsp;Abdul Rahim Muhammed Jasim ,&nbsp;Sulochana Priya ,&nbsp;Alaganandam Kumaran","doi":"10.1016/j.eujim.2024.102377","DOIUrl":"10.1016/j.eujim.2024.102377","url":null,"abstract":"<div><h3>Introduction</h3><p><em>Baliospermum montanum</em> (BM) is traditionally used to treat various ailments such as inflammation, rheumatoid arthritis, pain, etc. The root part of BM is well documented for its anti-inflammatory activity. However, the present study evaluates the multitargeted anti-inflammatory activity of the less explored BM leaf part. This is the first study investigating the COX-2, 15-LOX dual inhibiting potential and NO production inhibition of BM leaf extracts, fractions and compounds.</p></div><div><h3>Methods</h3><p>The BM leaf's water, ethanol, and hydroethanolic extracts were evaluated for anti-inflammatory activity by assessing the inhibition of COX-2, 15-LOX, and NO production. Additionally, the antioxidant potential of the extracts was determined through DPPH, ABTS, and FRAP assays. The most active ethanol extract was fractionated into 12 fractions and tested for anti-inflammatory, antioxidant, phenol and flavonoid content. Compounds were isolated from the most active fractions and identified using NMR techniques. The isolated compounds were checked for their anti-inflammatory activity. In addition, HPLC analysis of ethanol extract, fractions, and isolated compounds was carried out.</p></div><div><h3>Results</h3><p>The ethanol extract exhibited higher inhibition of COX-2, 15-LOX enzymes and NO production (IC₅₀ 35.75 ± 1.95 μg/mL) in LPS-treated RAW 264.7 cells. It also showed higher antioxidant activity. Following the fractionation of the ethanol extract using different solvents, only the ethyl acetate fractions demonstrated inhibition of COX-2, 15-LOX enzymes, and NO production. The ethyl acetate and acetone fractions are excellent sources of antioxidants, phenolic and flavonoid compounds. An effort to find the active principles from these ethyl acetate fractions resulted in the isolation and identification of four potent anti-inflammatory agents, namely, (-)-epiafzelechin, afzelechin-(4α→8)-afzelechin, afzelechin-(4α→8)-epiafzelechin and β-sitosterol-<span>d</span>-glycoside. The first three compounds were reported for the first time from this plant and afzelechin-(4α→8)-afzelechin was found to be a potent inhibitor of the COX-2/15 LOX enzyme as well as NO production (IC₅₀ = 5.9 ± 1.09 µM).</p></div><div><h3>Conclusion</h3><p>Based on these findings, we conclude that ethanol extract, fractions, and isolated compounds exert anti-inflammatory activity through multiple therapeutic mechanisms. The present study scientifically supports the traditional use of plant BM for treating inflammation and other related disorders.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102377"},"PeriodicalIF":1.9,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141405494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of Chinese herbal formula CDD-2103 for remission maintenance of ulcerative colitis: Study protocol for a randomized, double-blinded, placebo-controlled trial","authors":"Xuan Zhang ,&nbsp;Hor Yue Tan ,&nbsp;Wing Lam To ,&nbsp;Ziwan Ning ,&nbsp;Ka Wing Cheng ,&nbsp;Jialing Zhang ,&nbsp;Emily Au ,&nbsp;Keyi Zhou ,&nbsp;Hoi Ki Wong ,&nbsp;Heung Lam Mok ,&nbsp;Jiaruo Xu ,&nbsp;Matthew Koh ,&nbsp;Zhaoxiang Bian","doi":"10.1016/j.eujim.2024.102375","DOIUrl":"10.1016/j.eujim.2024.102375","url":null,"abstract":"<div><h3>Introduction</h3><p>Ulcerative colitis (UC) is a chronic lifelong disorder and a prominent subtype of inflammatory bowel disease (IBD) globally. Studies have indicated that Chinese herbal medicines (CHM) may offer advantages in alleviating the clinical symptoms experienced by UC patients. CDD (Centre for Chinese Herbal Medicine Drug Development)-2103 is a CHM formula for maintenance of UC remission. We aim to evaluate its efficacy and safety in remission patients with a traditional Chinese medicine (TCM) pattern of spleen deficiency with dampness obstruction (SDDO).</p></div><div><h3>Methods</h3><p>This study is a multi-center, randomized, double-blind, placebo-controlled clinical trial. A total of 82 eligible patients will be randomized to receive either CDD-2103 or placebo for 24 weeks, followed by post-treatment monitoring at week 36 and 48. The primary outcome is the recurrence rate according to the modified Mayo Score at week 24. The secondary outcomes consist of Partial Mayo Score, Inflammatory bowel disease questionnaire (IBDQ), Simple clinical colitis activity index (SCAAI), TCM syndrome scale and safety assessment.</p></div><div><h3>Conclusion</h3><p>This study will provide evidence on the effectiveness and safety of CDD-2103 in reducing chance of clinical relapse for UC patients, and will further shed light on the UC remission maintenance with TCM.</p></div><div><h3>Trial registration</h3><p>Chinese Clinical Trial Registry, ChiCTR2100043200. Registered on 8 February 2021. <span>https://www.chictr.org.cn/showproj.html?proj=121,692</span><svg><path></path></svg>.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102375"},"PeriodicalIF":1.9,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876382024000453/pdfft?md5=c0d787410cd1dd60ff45e10d5339e8af&pid=1-s2.0-S1876382024000453-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141410500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnobotanical exploration of botanical remedies used by traditional healers and herbalists for voice disorders","authors":"Hala Jarrar ,&nbsp;Mahmoud Alatrash ,&nbsp;Faten Amer","doi":"10.1016/j.eujim.2024.102374","DOIUrl":"10.1016/j.eujim.2024.102374","url":null,"abstract":"<div><h3>Background</h3><p>Traditional herbal medicine is an integral part of global healthcare, with a growing reliance on natural remedies. This study investigates herbal medicine practitioners' perspectives on plants used to treat voice disorders in Palestine.</p></div><div><h3>Methods</h3><p>A quantitative cross-sectional study was conducted in the West Bank of Palestine, involving 100 herbal medicine practitioners who completed a semi-structured questionnaire between March and June 2023. Information on herbs was collected, including their Arabic names, parts used, and preparation methods. Plant samples were preserved and identified at the pharmacognosy lab at An-Najah National University. Quantitative analysis employed fidelity level, use-value, and choice value to assess cultural and ecological aspects.</p></div><div><h3>Results</h3><p>The herbalists recommended 20 herbs. The top five herbs identified were <em>Anthemis cotula, Pimpinella anisum, Zingiber officinale, Clinopodium serpyllifolium</em>, and <em>Mentha spicata</em>, with fidelity levels ranging from 76 % to 96 %. Leaves and fruits were the most commonly utilized plant parts, with the Lamiaceae and Apiaceae families being the most frequent.</p></div><div><h3>Conclusion</h3><p>Folkloric herbal medicine contributes to community healthcare and drug development. This study documents 20 indigenous Palestinian phyto-remedies that enhance vocal health, highlighting rich traditional knowledge. Collaboration between traditional healers and healthcare professionals can offer informed recommendations, while educational programs bridge traditional and contemporary healthcare. This pioneering research provides valuable insights globally, being the first to explore herbalists' indigenous knowledge of voice disorder remedies. While focusing on the West Bank, its implications extend worldwide, guiding future research into herbal remedies for voice disorders.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102374"},"PeriodicalIF":1.9,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141410816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and implementation of an evidence-based biofield therapy standardized documentation tool","authors":"Paul Guillory ,&nbsp;Tanecia Blue ,&nbsp;John Casken ,&nbsp;Courtnee Nunokawa","doi":"10.1016/j.eujim.2024.102369","DOIUrl":"10.1016/j.eujim.2024.102369","url":null,"abstract":"<div><h3>Introduction</h3><p>Biofield therapy (BT) is a complementary health practice involving the use of subtle energy to promote healing; however, monitoring the quality of care after implementing a BT program can be particularly challenging. The aim of this project was to strategically design, implement, and evaluate an evidence-based BT documentation tool to capture relevant data elements to display in a quality metric dashboard, while also being satisfactory to the practitioners who use it.</p></div><div><h3>Methods</h3><p>Utilizing the Consolidated Framework for Implementation Research (CFIR) method, key stakeholders at a government healthcare facility were gathered to design and use a structured documentation tool. After the tool's deployment, the stakeholders were routinely assessed over a three-month period to evaluate its effectiveness and identify areas for improvement. At the end of the period a practitioner satisfaction questionnaire was deployed and a quality metric dashboard was launched.</p></div><div><h3>Results</h3><p>Seven of the eleven BT-trained practitioners (64 %) used the template during the evaluation period and 255 sessions were documented. Forty-five percent of the staff responded to the Likert scored satisfaction questionnaire with 100 % indicating the template improved documentation, fit into the workflow, and facilitated interdisciplinary communication. The dashboard presented nine data elements, such as session indication and patient symptom scores, which can be filtered by date and location.</p></div><div><h3>Discussion</h3><p>The satisfaction scores validated findings from the literature relative to structured documentation, quality review, and program evaluation. These outcomes support the expansion of BT into different clinical settings, foster future BT research endeavors, and allow for BT to be included in broader medical data analytic efforts.</p></div><div><h3>Conclusion</h3><p>A structured documentation tool designed with findings from the evidence and input from key stakeholders can be an effective and satisfactory means of capturing quality metrics for evaluating the implementation of BT.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"68 ","pages":"Article 102369"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proposing a novel research method for acupoint selection","authors":"Nick Lowe,&nbsp;Spod Dutton","doi":"10.1016/j.eujim.2024.102372","DOIUrl":"10.1016/j.eujim.2024.102372","url":null,"abstract":"<div><h3>Introduction</h3><p>Acupoint selection in both clinical trials and practice is predominantly informed by traditional theory and experience rather than clinical or mechanistic research. In-clinic acupoint testing methods are used by some practitioners to help determine acupoint selection based on patient feedback, but to date no quantitative data on these approaches has been published. This paper reports preliminary data where an acupoint testing method was utilised to help inform acupoint selection. These results were then used to develop a theoretical framework to validate the acupoint testing approach as a novel research method.</p></div><div><h3>Methods</h3><p>Preliminary data on the acupoint testing method was collected as part of a routine clinic audit from a single private practice in the UK using an electronic health record (EHR) and included; patient clinical demographic data, health complaints categorised according to the International Classification of Primary Care (ICPC-2) codes and patient outcomes using a Patient Global Impression of Change (PGIC) scale. The acupoint testing method used acupressure and/or acupuncture on acupoints to establish whether there was an immediate positive therapeutic effect for a patient for either; i) local areas of pain, ii) restricted/painful range of movements (ROM) and/or iii) acute symptoms related to a patients’ health complaint.</p></div><div><h3>Results</h3><p>A total of 506 acupoint tests were recorded from 398 treatments delivered to 74 patients (63.5% female, 36.5% male, mean age 58 years) presenting with predominantly chronic (77.1%) musculoskeletal (65.7%) issues. Tests were recorded for 61/74 (82.4%) patients and the mean number of tests per patient was 8.3. The majority of test results were positive (78.5%). For most patients at least one positive and negative test was recorded (52.5%). Solely positive tests were recorded for 44.3% of patients and soley negative tests were recorded for 3.3% of patients. The mixture of positive and negative test results suggests acupoint specificity may be clinically relevant.</p></div><div><h3>Conclusion</h3><p>Preliminary data suggests the testing method was versatile and useful for informing acupoint selection in clinical practice. Further research is required to establish its validity and reliability. The acupoint testing approach may represent a valuable new research method to help inform acupoint selection for both clinical trials and practice.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"69 ","pages":"Article 102372"},"PeriodicalIF":2.5,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141144932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of acupuncture therapy for leukopenia after chemotherapy or radiotherapy: A systematic review and meta-analysis","authors":"Yunpeng Deng ,&nbsp;Huanhuan Zhang ,&nbsp;Tengteng Wei ,&nbsp;Guangshuai He ,&nbsp;Zhixin Zhu ,&nbsp;Shuning Zhang ,&nbsp;Meijun Liu ,&nbsp;Jingjing Xue ,&nbsp;Weixing Zhang ,&nbsp;Xuguang Yang","doi":"10.1016/j.eujim.2024.102373","DOIUrl":"10.1016/j.eujim.2024.102373","url":null,"abstract":"<div><h3>Introduction</h3><p>Acupuncture-Moxibustion Therapy (AMT) has been used to treat leukopenia associated with cancer treatment. This systematic review and meta-analysis aimed to assess the clinical efficacy, safety, and degree of evidence of AMT in the treatment of post-chemoradiotherapy leukopenia.</p></div><div><h3>Methods</h3><p>Four English databases (The Cochrane Library, PubMed, EMBASE, Web of Science) and four Chinese databases (Chinese Biomedical Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), and WanFang Database) were searched from inception to February 6, 2023 for randomized controlled trials (RCTs) regarding post-chemoradiotherapy leukopenia with AMT. Two authors extracted data and assessed the quality of trials through the Cochrane risk of bias tool 2.0 independently. All meta-analysis was performed using Review Manager 5.4.1 and GRADE was usually used to measure the certainty of evidence.</p></div><div><h3>Results</h3><p>The analysis included 18 RCTs with 1,377 patients. The results showed that in treating post-chemoradiotherapy leukopenia, AMT is more effective compared to Chinese herbal medicine (CHM) (e.g., the effective rate: risk ratio (RR)=1.33, 95 % confidence interval (CI) 1.16 to 1.53, 3 RCTs, 349 cases; the white blood cell count (WBC): standardized mean difference (SMD)=1.03, 95 %CI 0.04 to 2.01, 2 RCTs, 148 cases), experimental synthetic drugs (ESDs) (e.g., the effective rate: RR=1.35, 95 %CI 1.13 to 1.61, 3 RCTs, 184 cases; the WBC: SMD=1.43, 95 %CI 1.21 to 1.65, 3 RCTs, 244 cases). AMT in combination with myeloid growth factors (MGFs) significantly improved the effective rate (RR=1.21, 95 %CI 1.09 to 1.35, 3 RCTs, 187 cases) and WBC (SMD=1.86, 95 %CI 1.56 to 2.17, 2 RCTs, 117 cases) compared to MGFs. However, there are no data to support the benefits of AMT or in combination with drugs in terms of Karnofsky performance status scores. The certainty of the overall evidence is very low due to the small sample sizes and poor quality of the included RCTs.</p></div><div><h3>Conclusions</h3><p>Very low certainty evidence suggests that AMT may be an effective complementary therapy for post-chemoradiotherapy leukopenia. The present evidence does not support a definitive safety profile for AMT. However, the quality of the current studies are low, and these conclusions need to be further validated by conducting more high quality RCTs.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"68 ","pages":"Article 102373"},"PeriodicalIF":2.5,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S187638202400043X/pdfft?md5=aff8faba0e1cc7840759810f3f4a627a&pid=1-s2.0-S187638202400043X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}