European Journal of Integrative Medicine最新文献

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A cross-sectional study of mutual perceptions between conventional and traditional caregivers in the Democratic Republic of Congo: a step towards integrative medicine 刚果民主共和国传统和传统护理人员相互认知的横断面研究:迈向综合医学的一步
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-11 DOI: 10.1016/j.eujim.2025.102480
Cedrick S. Mutombo , Salvius A. Bakari , Vianney N. Ntabaza , Amandine Nachtergael , Jean-Baptiste S. Lumbu , Pierre Duez , Joh B. Kahumba
{"title":"A cross-sectional study of mutual perceptions between conventional and traditional caregivers in the Democratic Republic of Congo: a step towards integrative medicine","authors":"Cedrick S. Mutombo ,&nbsp;Salvius A. Bakari ,&nbsp;Vianney N. Ntabaza ,&nbsp;Amandine Nachtergael ,&nbsp;Jean-Baptiste S. Lumbu ,&nbsp;Pierre Duez ,&nbsp;Joh B. Kahumba","doi":"10.1016/j.eujim.2025.102480","DOIUrl":"10.1016/j.eujim.2025.102480","url":null,"abstract":"<div><h3>Introduction</h3><div>Although the Democratic Republic of Congo has been engaged for several years in the process of integrating traditional medicine (TM) into the official health system, to date, no study has reported on the interactions between caregivers from conventional medicine (CM) and TM. And so, the present work explores the perception of TM by CM caregivers, their collaboration with traditional healers (THs), and the opinions of caregivers of these two medicines on the integration of THs into CM structures.</div></div><div><h3>Methods</h3><div>Two semi-structured interview surveys were carried out between January 2018 and June 2019, among CM caregivers and THs in Lubumbashi, Democratic Republic of Congo.</div></div><div><h3>Results</h3><div>A total of 970 CM caregivers and 116 THs took part. More than 50.0 % of surveyed CM caregivers resorted to TM for various diseases and 78.7 % experienced treatment success. More than 80.0 % of THs wish to collaborate with CM caregivers and about 60.0 % of CM caregivers wish to collaborate with THs. Also, 30.5 % of CM caregivers desire the integration of THs in CM structures, while 77.6 % of THs want to work in said structures; moreover, 36.2 % and 16.0 % of TM and CM caregivers, respectively, mentioned having already experienced collaboration with traditional healers and their integration into CM structures.</div></div><div><h3>Conclusion</h3><div>There are some positive, and somewhat encouraging, interactions between TM and CM caregivers in Lubumbashi. The integration of TM knowledge in CM caregiver training courses, the generation and dissemination of data supporting the uses of traditional products and practices, as well as the development of mutual awareness and respect of caregivers in the two sectors are necessary actions to attain integrative medicine.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"76 ","pages":"Article 102480"},"PeriodicalIF":1.9,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143947066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Yoga as a complementary therapy in older adults: A bibliometric analysis based on the Web of Science database 瑜伽作为老年人的补充疗法:基于Web of Science数据库的文献计量学分析
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-10 DOI: 10.1016/j.eujim.2025.102478
Semiha Yenişehir
{"title":"Yoga as a complementary therapy in older adults: A bibliometric analysis based on the Web of Science database","authors":"Semiha Yenişehir","doi":"10.1016/j.eujim.2025.102478","DOIUrl":"10.1016/j.eujim.2025.102478","url":null,"abstract":"<div><h3>Introduction</h3><div>Yoga as a complementary therapy has an important biopsychosocial role in the active and successful ageing of the rapidly growing older population worldwide. The aim of this study is to analyse articles from a bibliometric perspective on yoga in older adults.</div></div><div><h3>Methods</h3><div>The Web of Science database was searched for the titles of English-language articles including “yoga” and (“geriatric” OR “aging” OR “older” OR “old age”) words. An R-based application (Biblioshiny-R), and VOSviewer software were used to analysis.</div></div><div><h3>Results</h3><div>A total of 125 English-articles published between 2005 and 2024 were included. The average citation per document was 19.50. The years with the highest number of publications were 2017 and 2022. The most productive research field was “Gerontology”. The most relevant author was Park J. USA was the most productive and most cited country and the most relevant country. “Journal of Alternative and Complementary Medicine” was the most relevant journal followed by “Complementary Therapies in Clinical Practice”. The most frequent author's keyword was “yoga”.</div></div><div><h3>Conclusion</h3><div>Most relevant countries’ findings about multiple-country publication indicate a significant lack of international collaboration. The number of most cited references should be increased for author network analysis to gain a deeper understanding of this field.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"76 ","pages":"Article 102478"},"PeriodicalIF":1.9,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144084716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between lifestyle factors, traditional Chinese medicine constitution types and vaginal microbiota health in women: A case-control study 生活方式因素、中医体质类型与女性阴道微生物群健康的关系:一项病例对照研究
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-09 DOI: 10.1016/j.eujim.2025.102476
Jiali Wei , Guohua Wang , Zehao Zheng , Yue Qiu , Xue Pan , Xinyu Li , Mei Han
{"title":"Association between lifestyle factors, traditional Chinese medicine constitution types and vaginal microbiota health in women: A case-control study","authors":"Jiali Wei ,&nbsp;Guohua Wang ,&nbsp;Zehao Zheng ,&nbsp;Yue Qiu ,&nbsp;Xue Pan ,&nbsp;Xinyu Li ,&nbsp;Mei Han","doi":"10.1016/j.eujim.2025.102476","DOIUrl":"10.1016/j.eujim.2025.102476","url":null,"abstract":"<div><h3>Introduction</h3><div>Vaginitis is an inflammatory condition of the female reproductive tract influenced by multiple factors, including hormone levels, lifestyle habits, and individual predispositions. In Traditional Chinese Medicine (TCM) theory, different constitution types can influence the onset and progression of vaginitis, as they determine an individual's internal balance of Yin and Yang, Qi, and Blood. This study aims to explore the correlation between lifestyle factors, TCM constitution types, and vaginal microecological abnormalities.</div></div><div><h3>Methods</h3><div>A case-control study was conducted at the Third Affiliated Hospital of Beijing University of Chinese Medicine between August and October 2024, involving women aged 18–45 with a history of sexual activity. The exposure variables encompassed age, lifestyle habits, and TCM constitution types, while the outcome variable focused on vaginal microecological abnormalities. Associations were assessed using logistic regression and Least Absolute Shrinkage and Selection Operator (LASSO) regression, with results reported as odds ratios (ORs) and 95 % confidence intervals (CIs).</div></div><div><h3>Results</h3><div>This study identified several significant risk factors for vaginal microecological imbalance. Univariate analysis showed differences between the abnormal (<em>n</em> = 334) and normal groups (<em>n</em> = 111) in reproductive infection score, sedentary hours, meat and dessert consumption, and TCM constitution types. Multivariate logistic regression confirmed reproductive infection score (OR = 1.2454, <em>P</em> &lt; 0.0001) and sedentary hours (OR = 1.3501, <em>P</em> = 0.0002) as key contributors, with meat consumption nearly doubling the risk (OR = 1.9941, <em>P</em> = 0.0230). Additionally, dampness-heat constitution (DHC) (OR = 6.6673, <em>P</em> = 0.0212) and qi-deficiency constitution (QDC) (OR = 3.9269, <em>P</em> = 0.0420) were associated with significantly higher risks of abnormal vaginal flora. LASSO regression analysis further emphasized the critical roles of reproductive infection score and sedentary hours in driving microecological imbalance.</div></div><div><h3>Conclusion</h3><div>Reproductive infection score and sedentary hours are significant contributors to vaginal microecological imbalance, while dietary habits and TCM constitution types, such as DHC and QDC, further influence the risk. These results provide valuable insights into the multifactorial nature of vaginal microecology and suggest that addressing these factors could improve preventive care and management.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"76 ","pages":"Article 102476"},"PeriodicalIF":1.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143937083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is chiropractic spinal manipulation effective for the treatment of cervicogenic, tension-type, or migraine headaches? A systematic review 脊椎推拿对治疗颈源性头痛、紧张性头痛或偏头痛有效吗?系统回顾
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-05 DOI: 10.1016/j.eujim.2025.102462
Luis Ceballos-Laita , Edzard Ernst , Andoni Carrasco-Uribarren , Daniel García-García , Sandra Jiménez-del-Barrio
{"title":"Is chiropractic spinal manipulation effective for the treatment of cervicogenic, tension-type, or migraine headaches? A systematic review","authors":"Luis Ceballos-Laita ,&nbsp;Edzard Ernst ,&nbsp;Andoni Carrasco-Uribarren ,&nbsp;Daniel García-García ,&nbsp;Sandra Jiménez-del-Barrio","doi":"10.1016/j.eujim.2025.102462","DOIUrl":"10.1016/j.eujim.2025.102462","url":null,"abstract":"<div><h3>Introduction</h3><div>Patients with headaches often seek complementary and alternative therapies, including chiropractic care. Chiropractic spinal manipulation is one of the most commonly used techniques for these patients; however, its effectiveness remains unclear. This systematic review aimed to evaluate the effectiveness of chiropractic spinal manipulation in reducing headache days, episode duration, episode intensity, and medication intake in patients with headaches.</div></div><div><h3>Methods</h3><div>MEDLINE (Pubmed), PEDro, SCOPUS, Cochrane Library and Web of Science databases were searched from inception to April 2024. PICO search strategy was used to identify randomized controlled trials applying chiropractic spinal manipulations versus sham manipulation, no additional intervention, or other conservative non-pharmacological interventions in patients with headaches. Eligible studies and data extraction were conducted independently by two reviewers. Quality of the studies was assessed with Physiotherapy Evidence Database scale, and risk of bias with Cochrane Collaboration tool. Certainty of the evidence was evaluated using GRADE approach.</div></div><div><h3>Results</h3><div>Eight studies ranging from low to high methodological quality were included in the synthesis without a meta-analysis. The results were categorized into three subgroups: chiropractic manipulation versus sham, chiropractic manipulation versus control, and chiropractic manipulation versus deep friction massage. Among the five studies comparing chiropractic manipulation to sham, two found a significant reduction in the number of headache days. Of the three studies comparing chiropractic manipulation to a control, one reported a decrease in headache episode duration. No significant differences were observed for any other variable across the subgroups. The certainty of evidence was downgraded to very low.</div></div><div><h3>Conclusions</h3><div>It is uncertain if chiropractic spinal manipulation is more effective than sham, control, or deep friction massage interventions for patients with headaches.</div></div><div><h3>PROSPERO registration number</h3><div>CRD42024518480</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"76 ","pages":"Article 102462"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence construction of Fufang Xueshuantong Capsule against retinal vein occlusion: A meta-analysis and network pharmacology 复方血栓通胶囊抗视网膜静脉闭塞的证据构建:荟萃分析和网络药理学
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-05 DOI: 10.1016/j.eujim.2025.102452
Nannan Shi , Jiaxian Li , Zhouzhou Jiang , Dachi Wang , Lina Liang
{"title":"Evidence construction of Fufang Xueshuantong Capsule against retinal vein occlusion: A meta-analysis and network pharmacology","authors":"Nannan Shi ,&nbsp;Jiaxian Li ,&nbsp;Zhouzhou Jiang ,&nbsp;Dachi Wang ,&nbsp;Lina Liang","doi":"10.1016/j.eujim.2025.102452","DOIUrl":"10.1016/j.eujim.2025.102452","url":null,"abstract":"<div><h3>Introduction</h3><div>Retinal vein occlusion (RVO) is the second most prevalent retinal vascular disease. In China, Fufang Xueshuantong Capsule (FXC) is a common compound Chinese medicine used to treat RVO. This review aims to illustrate the therapeutic efficacy and pharmacological mechanisms of FXC for RVO.</div></div><div><h3>Methods</h3><div>Eight databases were searched until 17 September 2024 to collect literature meeting the criteria. Two investigators independently assessed the quality of the review and used Stata 16.0 to meta-analyse each metric. Then, network pharmacology was performed to explore the underlying mechanisms of FXC in the treatment of RVO.</div></div><div><h3>Results</h3><div>A meta-analysis included 18 randomized control trials (RCTs) with 1574 patients. Our results indicated that compared to conventional/traditional Chinese medicine injection (TCM) therapies, FXC alone or in combination can enhance clinical effectiveness, raise best-corrected visual acuity (BCVA), reduce central macular thickness (CMT), improve hemorheology, ameliorate hemodynamic indices, enhance fundus morphology, and decrease TCM scores with a lower adverse reaction incident. Network pharmacology revealed core components included quercetin, β-sitosterol, formononetin, luteolin, tanshinone IIA, etc., and the core targets such as TGFβ1, PKC, JNK, ERK1/2, VEGF, MCP-1, VACM-1, IL-6, TNF-α, and Akt. Several of these targets and pathways are related to RVO, and the pharmacological mechanism is mainly related to the AGE-RAGE signaling pathway in diabetic complications.</div></div><div><h3>Conclusion</h3><div>FXC is clinically effective and safe for treating RVO. It synergistically treats RVO through a multi-component, multi-target, and multi-pathway network. The AGE-RAGE signaling pathway in diabetic complications may be one of the key pathways of FXC to ameliorate inflammation and thrombosis in RVO. Further basic experiments and high-quality RCTs are still needed to enrich the evidence chain for FXC in treating RVO.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"76 ","pages":"Article 102452"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144068638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the sedation effect of music intervention and remimazolam in elderly patients undergoing transurethral prostate resection under spinal anesthesia: A randomized controlled clinical trial 探讨音乐干预和雷马唑仑对老年脊髓麻醉下经尿道前列腺切除术患者的镇静作用:一项随机对照临床试验
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-04 DOI: 10.1016/j.eujim.2025.102455
Jing Wu , Sen Cai , Chang-Ming Wang , Xue-Song Wang
{"title":"Exploring the sedation effect of music intervention and remimazolam in elderly patients undergoing transurethral prostate resection under spinal anesthesia: A randomized controlled clinical trial","authors":"Jing Wu ,&nbsp;Sen Cai ,&nbsp;Chang-Ming Wang ,&nbsp;Xue-Song Wang","doi":"10.1016/j.eujim.2025.102455","DOIUrl":"10.1016/j.eujim.2025.102455","url":null,"abstract":"<div><h3>Introduction</h3><div>Pharmacological and non-pharmacological interventions are widely utilized in clinical practice for intraoperative sedation. However, the degree of sedation and side effects vary between the two modalities. This study aimed to explore the sedation effect of music intervention and remimazolam in elderly patients undergoing transurethral prostate resection (TURP) under spinal anesthesia.</div></div><div><h3>Methods</h3><div>Patients aged 60–80 years, scheduled for TURP under spinal anesthesia, were prospectively enrolled in this study and randomly assigned to no music group (Group A), music intervention group (Group B), remimazolam group (Group C), and remimazolam-combined-music intervention group (Group D). The primary outcome was assessed using the bispectral index (BIS). Secondary outcomes included blood pressure, heart rate (HR), pulse oxygen saturation (SpO<sub>2</sub>), cognitive function, the incidence of adverse events including body movement and coughing, and respiratory depression, as well as surgeon and patient satisfaction.</div></div><div><h3>Results</h3><div>The study randomly assigned 120 patients to four groups, with 117 patients ultimately included in the analysis. At specific time points, BIS values for Groups B [T7: 20 min after the start of TURP, T11: 60 min after the start of TURP and T14: leaving the operating room(OR)], C (T3–14: immediately after changing to lithotomy position to leaving the OR), and D (T3–14) were lower than those for Group A (<em>P</em> &lt; 0.05). Compared to Group A, significant decreases in blood pressure and SpO<sub>2</sub> were observed after intervention in Groups C and D, respectively (<em>P</em> &lt; 0.05). Although the incidence of adverse events, including body movement and coughing, was higher in Groups C and D compared to Group A (<em>P</em> &lt; 0.05), there was no significant difference in the incidence of respiratory depression. Significantly, surgeons reported lower satisfaction in Group C compared to Group A (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>While remimazolam induced deeper sedation, music intervention offered only a slight sedative effect. However, remimazolam also increased the incidence of body movement and coughing, which potentially reduced surgeon satisfaction.</div></div><div><h3>Clinical trial registration</h3><div>ChiCTR2300071284</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"76 ","pages":"Article 102455"},"PeriodicalIF":1.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and content validation of integrated yoga module for patients with essential tremor 特发性震颤患者综合瑜伽模块的开发与内容验证
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-04 DOI: 10.1016/j.eujim.2025.102463
Mrityunjay Patidar , Deepika Joshi , Neeru Nathani
{"title":"Development and content validation of integrated yoga module for patients with essential tremor","authors":"Mrityunjay Patidar ,&nbsp;Deepika Joshi ,&nbsp;Neeru Nathani","doi":"10.1016/j.eujim.2025.102463","DOIUrl":"10.1016/j.eujim.2025.102463","url":null,"abstract":"<div><h3>Introduction</h3><div>Essential tremor (ET) is a neurological disorder defined as upper limb action tremor occurring bilaterally, for minimum 3 years duration. ET significantly impacts daily functioning and quality of life (QoL) among patients. Yogic practices have significant impact on movement disorders and improve QoL; however, a specific Yoga module for ET is not available. The aim of this study was the development and content validation of an integrated Yoga module (IYM) for patients with ET.</div></div><div><h3>Methods</h3><div>The IYM was designed on the basis of traditional and contemporary yogic literature and relevant clinical studies. For content validity it was sent to 32 Yoga experts along with a single case vignette of a hypothetical ET patient. Yoga experts were asked to rate the usefulness of practices on a scale from 1–5 (5=extremely essential).</div></div><div><h3>Results</h3><div><strong>:</strong> A total of 27 Yoga experts responded. Out of 38 practices, 31 scored content validity ratio (CVR) &gt; 0.37 and were retained for IYM. The experts opined that the IYM would be helpful for patients with ET.</div></div><div><h3>Conclusion</h3><div><strong>:</strong> The IYM developed for patients with ET possesses adequate face and content validity. This study has limitations, including validation with only 27 experts, which could be strengthened with a larger group. Additionally, applying a validated consensus method, such as the Delphi technique, could have helped minimize potential biases in expert opinions. A feasibility study is suggested to evaluate the adaptability of the IYM, while a randomized controlled trial is recommended to assess its clinical efficacy.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"76 ","pages":"Article 102463"},"PeriodicalIF":1.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143937084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bloodletting therapy to manage fever caused by infectious diseases: A systematic review of randomized controlled trials 放血疗法治疗感染性疾病引起的发热:随机对照试验的系统回顾
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.eujim.2025.102441
Shuai Dong , Meng-Fang Xu , Xin-Hao Li , Ye-Xin Zhang , Nicola Robinson , Xin-Xin Yang , Hui-Juan Cao
{"title":"Bloodletting therapy to manage fever caused by infectious diseases: A systematic review of randomized controlled trials","authors":"Shuai Dong ,&nbsp;Meng-Fang Xu ,&nbsp;Xin-Hao Li ,&nbsp;Ye-Xin Zhang ,&nbsp;Nicola Robinson ,&nbsp;Xin-Xin Yang ,&nbsp;Hui-Juan Cao","doi":"10.1016/j.eujim.2025.102441","DOIUrl":"10.1016/j.eujim.2025.102441","url":null,"abstract":"<div><h3>Introduction</h3><div>Bloodletting therapy (BLT), a traditional Chinese medicine (TCM) non-pharmaceutical therapy, may have a good antipyretic effect, but the evidence has not been evaluated. The aim of this systematic review was to assess the antipyretic effect and safety of TCM BLT used in patients with infections.</div></div><div><h3>Methods</h3><div>The protocol of this review was registered in PROSPERO (No.CRD42023411059). We included randomized controlled trials (RCTs) comparing BLT alone or in combination with another therapy to controls (no treatment or usual care). A search of CNKI, Wanfang, VIP, Sinomed, Cochrane Library, PubMed, and Embase databases was conducted up to March 2023. Cochrane Risk of Bias 2.0 tool and GRADE were used for assessing methodological quality of included trials and certainty of evidence.</div></div><div><h3>Result</h3><div>Fourteen RCTs (1419 participants) were included. BLT (either used alone or as add on therapy) was superior to drugs alone in increasing antipyretic rate and lowering the body temperature only for adults. For children or when combined with pediatric Tuina or herbal medicine, its advantages were not shown. The fever clearance time may be shortened (Mean Difference (MD)=-7.59 h, 95 %CI -12.73 h to -2.44 h, 194 participants, <em>I<sup>2</sup></em>=69 %, 3 trials, <em>P</em> <em>=</em> 0.004) and the commencement of fever abatement (MD=-1.48 h, 95 %CI -2.02 h to -0.94 h, 134 participants, <em>I<sup>2</sup></em>=0 %, 2 trials, <em>P</em> &lt; 0.00001) improved when used as an adjunctive treatment with pediatric Tuina. Safety of BLT to treat fever was still unclear since few trials reported this relevant outcome. Certainty of evidence was very low.</div></div><div><h3>Conclusion</h3><div>The long-term (24hrs+) antipyretic effect of BLT alone and combined with drugs may be better than that of drugs alone for adults. For children combining BLT and pediatric Tuina/herbal medicine was no better in increasing antipyretic rate compared to pediatric Tuina/herbal medicine alone. Current evidence does not provide firm conclusions about the safety of BLT.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"75 ","pages":"Article 102441"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143746572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salvia miltiorrhiza in angina pectoris and myocardial infarction: A bibliometric analysis 丹参治疗心绞痛和心肌梗死:文献计量学分析
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.eujim.2025.102445
Qi Lan , Jin-Wen Wu , Ding-Shan Zhang , Yu-Mei Qian , Xin-Rui Yang , Ting Peng , Zhen-Xun Wan , Ping Liu , Yan Jiang , Meng-Nan Liu
{"title":"Salvia miltiorrhiza in angina pectoris and myocardial infarction: A bibliometric analysis","authors":"Qi Lan ,&nbsp;Jin-Wen Wu ,&nbsp;Ding-Shan Zhang ,&nbsp;Yu-Mei Qian ,&nbsp;Xin-Rui Yang ,&nbsp;Ting Peng ,&nbsp;Zhen-Xun Wan ,&nbsp;Ping Liu ,&nbsp;Yan Jiang ,&nbsp;Meng-Nan Liu","doi":"10.1016/j.eujim.2025.102445","DOIUrl":"10.1016/j.eujim.2025.102445","url":null,"abstract":"<div><h3>Introduction</h3><div>Angina pectoris and myocardial infarction, as the common causes and symptoms of cardiovascular disease, are one of the important research fields of traditional and complementary medicine. Using bibliometric methods, this study conducted a multidimensional analysis of the research trajectory of Salvia miltiorrhiza in the treatment of angina pectoris and myocardial infarction from 2007 to 2024, with a focus on its research characteristics, hot spots and frontiers.</div></div><div><h3>Methods</h3><div>Title, topic, abstract and author keywords related to Salvia miltiorrhiza, myocardial infarction and angina pectoris were utilized in the Web of Science Core Collection database to maximize the search related to the research topic. Co-authorship, co-occurrence and co-citation analysis of publications, countries, institutions, journals, authors, references and keywords were conducted using Citespace 6.3.R1, SCImago Graphica Beta 1.0.42, VOSviewer, Bibliometrix R Package and Microsoft Excel.</div></div><div><h3>Results</h3><div>The annual publication volume of studies related to the treatment of angina pectoris and myocardial infarction using Salvia miltiorrhiza exhibits phased changes, demonstrating a general upward trend. China is the country with the highest number of publications and citations, and it has established collaborations with multiple countries. Canada and India have emerged as significant participants in recent years. The number of authors and publications meets the requirements of Price's Law and the core author in this research field is Li, Xiang. The top three keywords are Salvia miltiorrhiza (75 occurrences), myocardial infarction (70 occurrences) and Danshen(37 occurrences).</div></div><div><h3>Conclusions</h3><div>The current hotspots of Salvia miltiorrhiza in the treatment of angina pectoris and myocardial infarction mainly focus on three aspects: the pharmacological effects of this herb and its active ingredients, the treatment mechanism of angina pectoris and myocardial infarction, and the physiological and pathological relationship of its network pharmacology. These findings not only provide a solid foundation for the clinical application of Salvia miltiorrhiza but also demonstrate its potential in preventing and controlling cardiovascular diseases.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"75 ","pages":"Article 102445"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complementary and integrative health approaches used for pain management by U.S. adults with chronic fatigue syndrome/myalgic encephalomyelitis: Findings from the 2022 National Health Interview Survey 美国成年慢性疲劳综合征/脑脊髓灰质炎患者用于缓解疼痛的补充和综合保健方法:2022 年全国健康访谈调查的结果
IF 1.9 4区 医学
European Journal of Integrative Medicine Pub Date : 2025-04-01 DOI: 10.1016/j.eujim.2025.102443
Jenna L. Adamowicz , Zoe Sirotiak , Emily B.K. Thomas , Brian C. Lund , Katherine Hadlandsmyth , Mary A. Driscoll
{"title":"Complementary and integrative health approaches used for pain management by U.S. adults with chronic fatigue syndrome/myalgic encephalomyelitis: Findings from the 2022 National Health Interview Survey","authors":"Jenna L. Adamowicz ,&nbsp;Zoe Sirotiak ,&nbsp;Emily B.K. Thomas ,&nbsp;Brian C. Lund ,&nbsp;Katherine Hadlandsmyth ,&nbsp;Mary A. Driscoll","doi":"10.1016/j.eujim.2025.102443","DOIUrl":"10.1016/j.eujim.2025.102443","url":null,"abstract":"<div><h3>Introduction</h3><div>While most persons with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) experience pain, traditional pain treatments may be harmful or unfavorable to this population. Complementary and integrative health approaches for pain management offer a potentially important alternative. However, there is a paucity of research regarding which pain treatments patients with CFS/ME use. This study examined the prevalence of pain-related complementary and integrative health usage in CFS/ME adults and the factors that may be associated with usage, such as sex and anxious and depressive symptoms.</div></div><div><h3>Methods</h3><div>Using 2022 U.S. National Health Interview Survey data, seven different complementary and integrative health approaches were examined. Survey weights and variance estimation variables were utilized, and Rao-Scott chi-square test examined group-based differences.</div></div><div><h3>Results</h3><div>A total of 453 individuals (1.6 %) reported currently having CFS/ME. About one third (32.3 %) of the CFS/ME sample reported using complementary and integrative health approaches for pain management. The most commonly reported treatments were meditation (15.1 %), chiropractic care (14.5 %), and massage (10.7 %). Females with CFS/ME were significantly more likely to use pain-related complementary and integrative health approaches relative to their male counterparts (39.1 % vs. 24.3 %, respectively; χ<sup>2</sup> (1) = 5.90, <em>p</em> = 0.015). Usage of pain-related complementary and integrative health approaches did not differ significantly among those with or without clinically elevated anxious or depressive symptoms.</div></div><div><h3>Conclusions</h3><div>Overall, persons with CFS/ME appear to use pain-related complementary and integrative health modalities at a lower rate relative to the general population. Although complementary and integrative health use was common, over half of the sample were not using these modalities, highlighting an opportunity for broader dissemination for pain management purposes.</div></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":"75 ","pages":"Article 102443"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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